The impact of substance use disorders on the course of schizophrenia—A 15-year follow-up study
Abstract
Background This follow-up study compared patients with schizophrenia with co-occurring substance use disorder to patients with schizophrenia and no substance use disorder.Aims To investigate the prognostic significance of the effects of substance use disorders on the course of schizophrenia.Method Patients with schizophrenia and co-occurring substance use disorder (n=107), and patients with schizophrenia only (n=119) were followed over a 15-year period through the use of national hospitalization registers, data for time and cause of death, and data for homelessness or institutionalization.Results The median length of psychiatric hospitalization was 12 days for a patient with dual diagnosis, and 21 days for patients with schizophrenia only. Patients with dual diagnosis displayed a significantly elevated usage of all types of hospital contacts except inpatient treatment for non-psychiatric disorders. In three types of hospital contacts, patients with co-occurring substance use had approximately two to three times as many hospitalizations as did patients with schizophrenia only. Rates for homelessness and institutionalization were similar in both groups. Patients with a dual diagnosis were also significantly more at risk of dying during follow-up than were patients with schizophrenia only.Conclusions The findings suggest that the long-term course of schizophrenia is considerably more severe in patients who have a dual diagnosis compared to patients with schizophrenia only Substance use disorders have a substantial impact on the hospitalization rates of patients with schizophrenia, as well as on life expectancy. Patients with co-morbid substance abuse are more likely to be admitted for treatment during a given year although they have briefer contact with treatment.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A study focusing on patients with schizophrenia and substance abuse found age at death particularly low (49 years).
“A study focusing on patients with schizophrenia and substance abuse, i.e., a dual diagnosis (Schmidt et al. 2011), found that age at death for these patients was particularly low (49 years).”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Schmidt et al. 2011
Conflicting results have been recently reported as to whether illicit drug use contributes to excess mortality in psychosis.
“Conflicting results have been recently reported as to whether illicit drug use contributes to excess mortality in psychosis.2,25,26”
From Mortality in Schizophrenia and Other Psychoses: A 10-Year Follow-up of the ӔSOP First-Episode Cohort (2015) · cites this paper as [26]
Cites
Psychiatric Comorbidities and Schizophrenia
Buckley, P. F., Miller, B. J., Lehrer, D. S., & Castle, D. J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn135 · Cited by 1,121 · see citing works
Substance Use Disorders in Schizophrenia--Clinical Implications of Comorbidity
Volkow, N. D. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp016 · Cited by 272 · see citing works
McGurk, S. R., Mueser, K. T., DeRosa, T., & Wolfe, R. S. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn182 · Cited by 271 · see citing works
Horsfall, J. M., Cleary, M. L., Hunt, G. E., & Walter, G. (2009) · Harvard Review of Psychiatry · doi:10.1080/10673220902724599 · Cited by 237 · see citing works
Kavanagh, D. J., Waghorn, G., Jenner, L., Chant, D. C., Carr, V. J., Evans, M., Herrman, H., Jablensky, A. V., & McGrath, J. J. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)00130-0 · Cited by 184 · see citing works
Ten-Year Recovery Outcomes for Clients With Co-Occurring Schizophrenia and Substance Use Disorders
Drake, R. E., McHugo, G. J., Xie, H., Fox, M., Packard, J. D., & Helmstetter, B. S. (2005) · Schizophrenia Bulletin · doi:10.1093/schbul/sbj064 · Cited by 150 · see citing works
A multicentre inter-rater reliability study using the OPCRIT computerized diagnostic system
Williams, J. H., FARMER, A. E., Ackenheil, M., Kaufmann, C. A., & McGuffin, P. (1996) · Psychological Medicine · doi:10.1017/s003329170003779x · Cited by 135 · see citing works
Botha, U. A., Koen, L., Joska, J. A., Parker, J. S., Horn, N. R., Hering, L., & Oosthuizen, P. P. (2009) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-009-0085-6 · Cited by 123 · see citing works
Assessment and Treatment Selection for “Revolving Door” Inpatients with Schizophrenia
Weiden, P. J., & Glazer, W. M. (1997) · Psychiatric Quarterly · doi:10.1023/a:1025499131905 · Cited by 121 · see citing works
Risk Factors for Violent Crime in Schizophrenia
Fazel, S., Grann, M., Carlström, E. L., Lichtenstein, P., & Långström, N. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04274 · Cited by 104 · see citing works
Xie, H., McHugo, G. J., Fox, M. B., & Drake, R. E. (2005) · Psychiatric Services · doi:10.1176/appi.ps.56.10.1282 · Cited by 104 · see citing works
Comorbid Schizophrenia and Substance Abuse: A Review of Epidemiology and Course
Westermeyer, J. J. (2006) · American Journal on Addictions · doi:10.1080/10550490600860114 · Cited by 88 · see citing works
Continuity of Care After Inpatient Discharge of Patients With Schizophrenia in the Medicaid Program
Olfson, M., Marcus, S. C., & Doshi, J. A. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m05969yel · Cited by 80 · see citing works
Epidemiology of suicide attempts among persons with psychotic disorder in the general population
Suokas, J. T., Perälä, J., Suominen, K. H., Saarni, S. I., Lönnqvist, J. K., & Suvisaari, J. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.09.009 · Cited by 78 · see citing works
Psychiatric Hospital Outcomes of Dual Diagnosis Patients Under Managed Care
Leon, S. C., Lyons, J. S., Christopher, N. J., & Miller, S. I. (1998) · American Journal on Addictions · doi:10.3109/10550499809034715 · Cited by 39 · see citing works
Bennett, M. E., Bellack, A. S., Brown, C. H., & DiClemente, C. C. (2009) · Addictive Behaviors · doi:10.1016/j.addbeh.2009.03.023 · Cited by 33 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Excess early mortality in schizophrenia.
Laursen, T. M., Nordentoft, M., & Mortensen, P. B. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153657 · Cited by 913 · see citing works
Hunt, G. E., Large, M. M. B., Cleary, M. L., Lai, H. M. X., & Saunders, J. B. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.07.011 · Cited by 483 · see citing works
Life expectancy and cardiovascular mortality in persons with schizophrenia
Laursen, T. M., Munk-Olsen, T., & Vestergaard, M. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32835035ca · Cited by 518 · see citing works
Psychosocial Treatments for Schizophrenia
Mueser, K. T., Deavers, F. E., Penn, D. L., & Cassisi, J. E. (2013) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050212-185620 · Cited by 406 · see citing works
Psychosocial Interventions for People With Both Severe Mental Illness and Substance Misuse
Hunt, G. E., Siegfried, N., Morley, K. C., Sitharthan, T., & Cleary, M. L. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt160 · Cited by 282 · see citing works
Schizophrenia--Time to Commit to Policy Change
Fleischhacker, W. W., Arango, C., Arteel, P., Barnes, T. R. E., Carpenter, W., Duckworth, K., Galderisi, S., Halpern, L., Knapp, M., Marder, S. R., et al. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu006 · Cited by 214 · see citing works
Lewer, D., Freer, J., King, E., Larney, S., Degenhardt, L. J., Tweed, E., Hope, V. D., Harris, M., Millar, T., Hayward, A. C., et al. (2019) · Addiction · doi:10.1111/add.14892 · Cited by 179 · see citing works
Mortality in Schizophrenia and Other Psychoses: A 10-Year Follow-up of the ӔSOP First-Episode Cohort
Reininghaus, U., Dutta, R., Dazzan, P., Doody, G. A., Fearon, P., Lappin, J., Heslin, M., Onyejiaka, A., Donoghue, K., Lomas, B., et al. (2015) · Schizophrenia Bulletin · doi:10.1093/schbul/sbu138 · Cited by 156 · see citing works
Psychosocial interventions for people with both severe mental illness and substance misuse
Hunt, G. E., Siegfried, N., Morley, K. C., Sitharthan, T., & Cleary, M. L. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001088.pub3 · Cited by 117 · see citing works
Crockford, D. N., & Addington, D. E. (2017) · The Canadian Journal of Psychiatry · doi:10.1177/0706743717720196 · Cited by 113 · see citing works
Causes of mortality in schizophrenia: an updated review of European studies
Department of Psychiatry, W. M. U., Piotrowski, P., M. Gondek, T., Department of Psychiatry, W. M. U., Królicka-Deręgowska, A., Department of Psychiatry, W. M. U., Misiak, B., Department of Genetics, W. M. U., Adamowski, T., Department of Nervous System Diseases, F. O. H. S., et al. (2017) · Psychiatria Danubina · doi:10.24869/psyd.2017.108 · Cited by 107 · see citing works
“Apart from schizophrenia, they also analysed mortality in people diagnosed with: substance abuse (Chang et al. 2010, Schmidt et al. 2011), affective disorder (Laursen et al. 2009, Chang et al. 2010, Laursen et al. 2011, Laursen 2011, Hoang et al. 2011, Hoang et al. 2013), schizoaffective disorder…”
BackgroundInfluentialPsychosocial interventions for people with both severe mental illness and substance misuse
Hunt, G. E., Siegfried, N., Morley, K., Brooke-Sumner, C., & Cleary, M. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001088.pub4 · Cited by 105 · see citing works
Treatment of Co-Occurring Psychotic and Substance Use Disorders
Mueser, K. T., & Gingerich, S. L. (2013) · Social Work in Public Health · doi:10.1080/19371918.2013.774676 · Cited by 86 · see citing works
Heiberg, I. H., Jacobsen, B. K., Nesvåg, R., Bramness, J. G., Reichborn‐Kjennerud, T., Næss, Ø., Ystrøm, E., Hultman, C. M., & Høye, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202028 · Cited by 94 · see citing works
The Effect of Substance Use on 10-Year Outcome in First-Episode Psychosis
Weibell, M. A., Hegelstad, W. T. V., Auestad, B., Bramness, J. G., Evensen, J. H., Haahr, U., Joa, I., Johannessen, J. O., Larsen, T. K., Melle, I. S., et al. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw179 · Cited by 81 · see citing works
Morbidity and mortality in schizophrenia with comorbid substance use disorders
Lähteenvuo, M., Batalla, A., Luykx, J. J., Mittendorfer‐Rutz, E., Tanskanen, A. J., Tiihonen, J., & Taipale, H. T. (2021) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13291 · Cited by 78 · see citing works
Hjemsæter, A. J., Bramness, J. G., Drake, R. E., Skeie, I., Monsbakken, B., Benth, J. Š., & Landheim, A. S. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2077-8 · Cited by 71 · see citing works
Clinical presentations and diagnostic issues in dual diagnosis disorders
Morojele, N. K., Saban, A., & Seedat, S. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328351a429 · Cited by 63 · see citing works
Mortality and Its Determinants in People With Psychotic Disorder
Suvisaari, J., Partti, K., Perälä, J., Viertiö, S., Saarni, S. E., Lönnqvist, J. K., Saarni, S. I., & Härkänen, T. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31827ad512 · Cited by 63 · see citing works
Yung, A. R., Cotter, J., Wood, S. J., McGorry, P. D., Thompson, A. D., Nelson, B., & Lin, A. P. (2015) · Psychological Medicine · doi:10.1017/s003329171500135x · Cited by 57 · see citing works
Román, V., Gyertyán, I., Sághy, K., Kiss, B., & Szombathelyi, Z. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2906-7 · Cited by 56 · see citing works
Eack, S. M., Hogarty, S. S., Greenwald, D. P., Litschge, M. Y., McKnight, S. A. F., Bangalore, S. S., Pogue‐Geile, M. F., Keshavan, M. S., & Cornelius, J. R. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.11.017 · Cited by 56 · see citing works
Adan, A., Capella, M. D. M., Prat, G., Forero, D. A., López-Vera, S., & Navarro, J. F. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169943 · Cited by 50 · see citing works
Refining and integrating schizophrenia pathophysiology – Relevance of the allostatic load concept
Misiak, B., Frydecka, D., Zawadzki, M., Krefft, M., & Kiejna, A. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.06.004 · Cited by 47 · see citing works
Factors and their weight in reducing life expectancy in schizophrenia
Correll, C. U., Bitter, I., Hoti, F. J., Mehtälä, J., Wooller, A., Pungor, K., & Tiihonen, J. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.10.019 · Cited by 44 · see citing works
Jeanblanc, J., Balguerie, K., Coune, F., Legastelois, R., Jeanblanc, V., & Naassïla, M. (2014) · Addiction Biology · doi:10.1111/adb.12146 · Cited by 40 · see citing works
Glover‐Wright, C., Coupe, K., Campbell, A. C., Keen, C., Lawrence, P., Kinner, S. A., & Young, J. T. (2023) · Drug and Alcohol Review · doi:10.1111/dar.13651 · Cited by 39 · see citing works
Kučerová, J., Babinská, Z., Amchová, P., Štark, T., Drago, F., Šulcová, A., & Micale, V. (2016) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2016.1190032 · Cited by 38 · see citing works
The Cannabis Pathway to Non-Affective Psychosis may Reflect Less Neurobiological Vulnerability
Løberg, E., Helle, S., Nygård, M., Berle, J. Ø., Kroken, R. A., & Johnsen, E. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00159 · Cited by 37 · see citing works
Mueser, K. T., Gottlieb, J. D., Cather, C., Glynn, S. M., Zárate, R., Smith, M. F., Clark, R. E., & Wolfe, R. S. (2011) · Psychosis · doi:10.1080/17522439.2011.639901 · Cited by 36 · see citing works
Psychosis, Mania and Criminal Recidivism: Associations and Implications for Prevention.
Lamberti, J., Katsetos, V., Jacobowitz, D. B., & Weisman, R. (2020) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000251 · Cited by 20 · see citing works
Cheng, T. C., & Robinson, M. A. (2013) · Health & Social Work · doi:10.1093/hsw/hlt005 · Cited by 35 · see citing works
Petersen, S. M., Toftdahl, N. G., Nordentoft, M., & Hjorthøj, C. R. (2019) · Addiction · doi:10.1111/add.14746 · Cited by 34 · see citing works
From apathy to addiction: Insights from neurology and psychiatry.
Kirschner, M., Rabinowitz, A. G., Singer, N., & Dagher, A. (2020) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109926 · Cited by 33 · see citing works
Szerman, N., Basurte-Villamor, I., Vega, P., Martı́nez-Raga, J., Parro-Torres, C., Almerge, J. C., Grau‐López, L., Matteis, M. D., & Árias, F. (2020) · Drugs - Real World Outcomes · doi:10.1007/s40801-020-00178-8 · Cited by 32 · see citing works
Lähteenvuo, M., Luykx, J. J., Taipale, H. T., Mittendorfer‐Rutz, E., Tanskanen, A. J., Batalla, A., & Tiihonen, J. (2022) · The British Journal of Psychiatry · doi:10.1192/bjp.2022.117 · Cited by 30 · see citing works
The Developmental Origins of Opioid Use Disorder and Its Comorbidities
Levis, S. C., Mahler, S. V., & Baram, T. Z. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.601905 · Cited by 29 · see citing works
Management of schizophrenia and comorbid substance use disorders: expert review and guidance
Neyra, A., Parro-Torres, C., Ros‐Cucurull, E., Machado, I. C., Echarri, E., & Torrens, M. (2024) · Annals of General Psychiatry · doi:10.1186/s12991-024-00529-7 · Cited by 28 · see citing works
Jeanblanc, J. (2015) · Current Addiction Reports · doi:10.1007/s40429-015-0076-5 · Cited by 28 · see citing works
Adán, A., Arredondo, A. Y., Capella, M. D. M., Prat, G., Forero, D. A., & Navarro, J. F. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.038 · Cited by 29 · see citing works
Tantirangsee, N., Assanangkornchai, S., & Marsden, J. (2014) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2014.10.011 · Cited by 25 · see citing works
Caplan, B., Zimmet, S. V., Meyer, E. C., Friedman‐Yakoobian, M. S., Monteleone, T., Leung, Y. J., Guyer, M. E., Rood, L. L., Keshavan, M. S., & Seidman, L. J. (2013) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2012.10.009 · Cited by 25 · see citing works
Thomsen, K. R., Thylstrup, B., Pedersen, M. M., Pedersen, M. U., Simonsen, E. H., & Hesse, M. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.09.026 · Cited by 25 · see citing works
Self-citationChallenges in working with patients with dual diagnosis
Pinderup, P. (2018) · Advances in Dual Diagnosis · doi:10.1108/add-11-2017-0021 · Cited by 24 · see citing works
Ruppelt, F., Rohenkohl, A. C., Kraft, V., Schöttle, D., Schröter, R., Gaianigo, J., Werkle, N., Daubmann, A., Karow, A., & Lambert, M. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.03.058 · Cited by 24 · see citing works
Opiate Dependence in Schizophrenia: Case Presentation and Literature Review
Kern, A., Akerman, S. C., & Nordstrom, B. R. (2013) · Journal of Dual Diagnosis · doi:10.1080/15504263.2013.867199 · Cited by 23 · see citing works
Making meaning of multimorbidity and severe mental illness: A viewpoint
Halstead, S., Siskind, D. J., & Warren, N. (2023) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674231195560 · Cited by 21 · see citing works
Pinderup, P. (2018) · Issues in Mental Health Nursing · doi:10.1080/01612840.2017.1398791 · Cited by 20 · see citing works
Functioning in patients with schizophrenia: A multicentre study evaluating the clinical perspective
Barrios, M., Gómez‐Benito, J., Pino, Ó., Rojo, E., & Guilera, G. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.05.079 · Cited by 20 · see citing works
Sentir, A. M., Bell, R. L., Engleman, E. A., & Chambers, R. A. (2018) · Addiction Biology · doi:10.1111/adb.12704 · Cited by 19 · see citing works
Hartberg, C. B., Lange, E. H., Lagerberg, T. V., Haukvik, U. K., Andreassen, O. A., Melle, I. S., & Agartz, I. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.11.019 · Cited by 18 · see citing works
오현주, Jang, S.-K., Lee, H.-S., Lee, E., & Choi, K. (2021) · Journal of Dual Diagnosis · doi:10.1080/15504263.2020.1839827 · Cited by 19 · see citing works
Using rodents to model schizophrenia and substance use comorbidity
Ng, E., McGirr, A., Wong, A. H. C., & Roder, J. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.03.025 · Cited by 17 · see citing works
Sweileh, W. M. (2024) · Annals of General Psychiatry · doi:10.1186/s12991-024-00517-x · Cited by 17 · see citing works
Güney, E., Alnıak, İ., & Erkıran, M. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102068 · Cited by 17 · see citing works
Destoop, M., Docx, L., Morrens, M., & Dom, G. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10040616 · Cited by 17 · see citing works
Addy, P. H., Radhakrishnan, R., Cortés, J. A., & D’Souza, D. C. (2012) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.10.2.140 · Cited by 17 · see citing works
Wojtalik, J. A., Hogarty, S. S., Cornelius, J. R., Phillips, M. L., Keshavan, M. S., Newhill, C. E., & Eack, S. M. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00186 · Cited by 16 · see citing works
von Greiff, N., Skogens, L., & Topor, A. (2018) · Nordic Social Work Research · doi:10.1080/2156857x.2018.1520739 · Cited by 16 · see citing works
Río-Martínez, L., Marquez-Arrico, J. E., Prat, G., & Adán, A. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061876 · Cited by 16 · see citing works
Substance use among Danish psychiatric patients: a cross-sectional study
Sørensen, T. M., Jespersen, H. S. R., Vinberg, M., Becker, U., Ekholm, O., & Fink‐Jensen, A. (2017) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2017.1400098 · Cited by 15 · see citing works
Anic, A., & Robertson, L. J. (2020) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v26i0.1526 · Cited by 15 · see citing works
Menne, V., & Chesworth, R. (2020) · Neuroanatomy and Behaviour · doi:10.35430/nab.2020.e10 · Cited by 15 · see citing works
Essential Elements of Forensic Assertive Community Treatment
Lamberti, J., & Weisman, R. (2021) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000299 · Cited by 12 · see citing works
Schizophrenia and oral health: Review of the literature
Đorđević, V., Đukić-Dejanović, S., Janković, L., & Todorović, L. (2016) · Balkan Journal of Dental Medicine · doi:10.1515/bjdm-2016-0002 · Cited by 15 · see citing works
Dupuy, M., Misdrahi, D., N’Kaoua, B., Tessier, A., Bouvard, A., Schweitzer, P., Auriacombe, M., Serre, F., Fatseas, M., & Swendsen, J. D. (2018) · Journal de Thérapie Comportementale et Cognitive · doi:10.1016/j.jtcc.2018.02.002 · Cited by 14 · see citing works
Training Changes Professionals’ Attitudes Towards Dual Diagnosis
Pinderup, P. (2016) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-016-9649-3 · Cited by 14 · see citing works
Florentin, S., Rosca, P., Raskin, S., Bdolah‐Abram, T., & Neumark, Y. D. (2019) · Journal of Dual Diagnosis · doi:10.1080/15504263.2019.1609149 · Cited by 14 · see citing works
Critical Review of Dual Diagnosis Training for Mental Health Professionals
Pinderup, P., Thylstrup, B., & Hesse, M. (2016) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-016-9665-3 · Cited by 13 · see citing works
Self-citationComorbid opioid use is undertreated among forensic patients with schizophrenia
Kivimies, K., Repo‐Tiihonen, E., Kautiainen, H., & Tiihonen, J. (2018) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/s13011-018-0177-y · Cited by 13 · see citing works
Thylstrup, B., Bloomfield, K., & Hesse, M. (2017) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.08.006 · Cited by 13 · see citing works
Self-citationSofer, M. M., Kaptsan, A., & Anson, J. (2018) · Journal of Dual Diagnosis · doi:10.1080/15504263.2018.1461965 · Cited by 12 · see citing works
Holst, C., Tolstrup, J. S., Sørensen, H. J., Pisinger, V. S. C., & Becker, U. (2019) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13002 · Cited by 13 · see citing works
Homelessness and Health Disparities: A Health Equity Lens
Bowen, E. A., Savino, R. F., & Irish, A. (2019) · Springer eBooks · doi:10.1007/978-3-030-03727-7_3 · Cited by 12 · see citing works
Kuussaari, K., & Hirschovits-Gerz, T. (2015) · Scandinavian Journal of Public Health · doi:10.1177/1403494815616303 · Cited by 12 · see citing works
Motivation deficits and use of alcohol and illicit drugs among individuals with schizophrenia
Bahorik, A. L., Greeno, C. G., Cochran, G., Cornelius, J. R., & Eack, S. M. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.04.012 · Cited by 12 · see citing works
Jahan, S., Wraith, D., Dunne, M. P., & Naish, S. (2021) · International Journal of Biometeorology · doi:10.1007/s00484-021-02160-7 · Cited by 11 · see citing works
Marquez-Arrico, J. E., Gonzalez-Sanchez, A., Navarro, J. F., Penadés, R., & Adán, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11226648 · Cited by 11 · see citing works
Rezansoff, S. N., Moniruzzaman, A., & Somers, J. M. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.05.031 · Cited by 11 · see citing works
Cognitive changes in patients with acute phase psychosis—Effects of illicit drug use
Helle, S., Gjestad, R., Johnsen, E., Kroken, R. A., Jørgensen, H. A., & Løberg, E. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.08.062 · Cited by 11 · see citing works
Burrer, A., Egger, S., Spiller, T. R., Kirschner, M., Homan, P., Seifritz, E., & Vetter, S. (2024) · BMC Medicine · doi:10.1186/s12916-024-03447-3 · Cited by 10 · see citing works
Courchesne‐Krak, N. S., Kepner, W. E., Rubano, A., & Marienfeld, C. B. (2022) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2021.100559 · Cited by 10 · see citing works
Helseth, V., Samet, S., Johnsen, J. T., Bramness, J. G., & Waal, H. (2012) · Journal of Dual Diagnosis · doi:10.1080/15504263.2012.749142 · Cited by 10 · see citing works
Views of schizophrenia patients on the effects of cannabis on their mental health
Parshotam, R. K., & Joubert, P. (2015) · South African Journal of Psychiatry · doi:10.7196/sajp.590 · Cited by 14 · see citing works
Green, J., Bagge, A. S. L., Olausson, S., Andiné, P., Wallinius, M., & Karlén, M. H. (2023) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2022.108899 · Cited by 9 · see citing works
Larsen, J. L., Johansen, K. S., & Mehlsen, M. Y. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.825701 · Cited by 9 · see citing works
Dionisie, V., Puiu, M. G., Manea, M. C., Moisă, E., Dumitru, A. M., Ibadula, L., Mareș, A. M., Varlam, C. I., & Manea, M. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1496750 · Cited by 9 · see citing works
Outcome of patients with dual diagnosis in secondary psychiatric care
Luoto, K. E., Koivukangas, A., Lassila, A., & Kampman, O. (2016) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2016.1160149 · Cited by 9 · see citing works
Florentin, S., Neumark, Y. D., Raskin, S., Bdolah‐Abram, T., & Rosca, P. (2020) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-020-01077-4 · Cited by 9 · see citing works
Optimizing Substance Use Treatment Selection Using Reinforcement Learning
Baucum, M., Khojandi, A., Myers, C. R., & Kessler, L. M. (2022) · ACM Transactions on Management Information Systems · doi:10.1145/3563778 · Cited by 7 · see citing works
Quality of life among dually diagnosed and non-substance-using male schizophrenia outpatients
Aras, H. İ., Yazar, M. S., & Altınbaş, K. (2013) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v19i2.416 · Cited by 9 · see citing works
Miller, A. P., Gizer, I. R., Fleming, W., Otto, J. M., Deak, J. D., Martins, J. S., & Bartholow, B. D. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.06.025 · Cited by 9 · see citing works
Tantirangsee, N., & Assanangkornchai, S. (2014) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2014.11.006 · Cited by 9 · see citing works
Alisauskiene, R., Løberg, E., Gjestad, R., Kroken, R. A., Jørgensen, H. A., & Johnsen, E. (2019) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2019.1622152 · Cited by 8 · see citing works
Genome-wide methylation analysis of treatment resistant schizophrenia
Luca, V. D., Chaudhary, Z., Al-Chalabi, N., Qian, J., Borlido, C., Gerretsen, P., Graff, A., Remington, G. J., & Chintoh, A. F. (2023) · Journal of Neural Transmission · doi:10.1007/s00702-022-02585-3 · Cited by 8 · see citing works
The European studies on mortality in schizophrenia
Gondek, T. M., Królicka, A., Piotrowski, P., & Kiejna, A. (2015) · Psychiatria Polska · doi:10.12740/pp/37845 · Cited by 8 · see citing works
Villalobos-Gallegos, L., Marín-Navarrete, R., Roncero, C., & González-Cantú, H. (2017) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2016-1972 · Cited by 8 · see citing works
Patel, R., Chan, K. M. Y., Palmer, E. O. C., Valko, M., Guruswamy, G., Ker, S., Batra, G., Rentería, M. E., & Kollins, S. H. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.08.023 · Cited by 7 · see citing works
Strålin, P., & Hetta, J. E. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.107919 · Cited by 7 · see citing works
Integrated Dual Disorder Treatment Implementation in a Large State Sample
Harrison, J., Curtis, A. B., Cousins, L. H., & Spybrook, J. K. (2016) · Community Mental Health Journal · doi:10.1007/s10597-016-0019-1 · Cited by 7 · see citing works
- Authors
- Schmidt, L. M., Hesse, M., & Lykke, J.
- Affiliations
- Sankt Hans Hospital (DK)
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 130
- Issue
- 1-3
- Pages
- 228-233
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2022066531
- Cited by
- 171
- References
- 16
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 10 · 2023: 8 · 2022: 12 · 2021: 10 · 2020: 13 · 2019: 13 · 2018: 15 · 2017: 15 · 2016: 12 · 2015: 11 · 2014: 10 · 2013: 17 · 2012: 10
- FWCI
- 8.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Health Professions › General Health Professions › Homelessness and Social Issues
- Keywords
- schizophrenia, substance use disorders
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cause of Death, Cross-Sectional Studies, Denmark, Female, Ill-Housed Persons, Humans, Longitudinal Studies, Male, Middle Aged, Predictive Value of Tests, Prognosis, Psychiatric Department, Hospital, Risk Factors, Schizophrenia, Time Factors, Diagnosis, Dual (Psychiatry), Substance-Related Disorders, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
