Microglial activation in a neuroinflammational animal model of schizophrenia – a pilot study
Juckel, Georg, Manitz, Marie Pierre, Brüne, Martin, Friebe, Astrid, Heneka, Michael T., Wolf, Rainer J.·2011·Schizophrenia Research
Cited by (165)
Items 101–165 of 165
- Psychopharmacological Treatment of Neurocognitive Deficits in People with Schizophrenia: A Review of Old and New TargetsAnthony O. Ahmed, Ishrat Bhat · 2014 · CNS Drugs
- Oxidative stress and schizophrenia: A comparative cross‐sectional study of multiple oxidative markers in patients and their first‐degree relativesEray Metin Güler, Ayşe Kurtulmuş, Ayşe Zehra Gül, Abdürrahim Koçyiğit, İsmet Kırpınar · 2021 · International Journal of Clinical Practice
- Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in miceKaurani, Lalit, Islam, Md Rezaul, Heilbronner, Urs, Krüger, Dennis M, Zhou, Jiayin, Methi, Aditi, Strauss, Judith, Pradhan, Ranjit, Schröder, Sophie, Burkhardt, Susanne et al. · 2024 · The EMBO Journal
- Recent advances in psychoneuroimmunology relevant to schizophrenia therapeuticsMonojit Debnath, Ganesan Venkatasubramanian · 2013 · Current Opinion in Psychiatry
- Neuroinflammatory Loop in Schizophrenia, Is There a Relationship with Symptoms or Cognition Decline?Claudio Carril Pardo, Karina Oyarce, América Vera-Montecinos · 2025 · International Journal of Molecular Sciences
- Characterizing the neuroimmune environment of offspring in a novel model of maternal allergic asthma and particulate matter exposureJuan M. Tamayo, Hadley C. Osman, Jared J. Schwartzer, Kent E. Pinkerton, Paul Ashwood · 2023 · Journal of Neuroinflammation
- Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental challengeMicaël Carrier, Chin Wai Hui, Valérie Watters, Eva Šimončičová, Katherine Picard, Fernando Gonzàlez Ibáñez, Nathalie Vernoux, Arnaud Droit, Michèle Desjardins, Marie‐Ève Tremblay · 2023 · Brain Behavior and Immunity
- Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activationKhalil, Omari S., Forrest, Caroline M., Pisar, Mazura, Smith, Robert A., Darlington, L. Gail, Stone, Trevor W. · 2013 · Immunopharmacology and Immunotoxicology
- Antipsychotic-like effect of minocycline in a rat model.Recep Dokuyucu, Mehmet Hanifi Kokaçya, Sema İnanır, Ümit Sertan Çöpoğlu, Oytun Erbaş · 2014 · PubMed Central
- Poly I:C‐induced maternal immune challenge reduces perineuronal net area and raises spontaneous network activity of hippocampal neurons in vitroDavid Wegrzyn, Marie Pierre Manitz, Michael Kostka, Nadja Freund, Georg Juckel, Andréas Faissner · 2020 · European Journal of Neuroscience
- The implications of hypothalamic abnormalities for schizophreniaHans‐Gert Bernstein, Gerburg Keilhoff, Johann Steiner · 2021 · Handbook of clinical neurology
- Cannabinoid receptor type 2 gene is associated with comorbidity of schizophrenia and cannabis dependence and fatty acid amide hydrolase gene is associated with cannabis dependence in the Spanish populationF. Árias, José Ramón Dávila Píriz, Alba Parra, Sergio Sánchez Romero, Eva María Sánchez‐Morla, Israel Ampuero, José Antonio Ramos Atance · 2021 · Adicciones
- Emotional Contagion is not Altered in Mice Prenatally Exposed to Poly (I:C) on Gestational Day 9Cristina Gonzalez-Liencres, Georg Juckel, Manuela Eßlinger, Simone Wachholz, Marie Pierre Manitz, Martin Brüne, Astrid Friebe · 2016 · Frontiers in Behavioral Neuroscience
- Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspringRyan J. Duchatel, Crystal L. Meehan, Lauren R. Harms, Patricia Therese Michie, Mark J. Bigland, Doug William Smith, Frederick Rohan Walker, Phillip Jobling, Deborah M. Hodgson, Paul A. Tooney · 2018 · Psychiatry Research
- CNS Macrophages and Infant InfectionsAlexander Oschwald, Philippe Petry, Katrin Kierdorf, Daniel Erny · 2020 · Frontiers in Immunology
- Commentary: Maternal immune activation evoked by polyinosinic: polycytidylic acid does not evoke microglial cell activation in the embryoHans‐Gert Bernstein, Yael Piontkewitz, Gerburg Keilhoff · 2016 · Frontiers in Cellular Neuroscience
- Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophreniaAnna M. Fiorito, Éric Fakra, Guillaume Sescousse, El Chérif Ibrahim, Romain Rey · 2023 · Translational Psychiatry
- A Weighted Gene Co-expression Network Analysis Reveals lncRNA Abnormalities in the Peripheral Blood Associated With Ultra-High-Risk for PsychosisYan Xin Ren, Wei Li, Sha Liu, Zhi Li, Jiaying Wang, Hong Yang, Yong Ji Xu · 2020 · Frontiers in Psychiatry
- Interleukin-6 produces behavioral deficits in pre-pubescent mice independent of neuroinflammationFernando Janczur Velloso, Rebecca Zaritsky, Rouba Y. Houbeika, Nicolas Rios, Steven W. Levison · 2025 · Brain Behavior and Immunity
- Neuroimmune and behavioral changes elicited by maternal immune activation in mice are ameliorated by early postnatal immune stimulationLourdes K. Davis, Louise Madeleine Ince, Sriya Gullapalli, Laura K. Fonken · 2025 · Brain Behavior and Immunity
- Microglia and microbiome in schizophrenia: can immunomodulation improve symptoms?Georg Juckel, Nadja Freund · 2023 · Journal of Neural Transmission
- Effect of dimethyl fumarate on the changes in the medial prefrontal cortex structure and behavior in the poly(I:C)-induced maternal immune activation model of schizophrenia in the male miceFarshid Bagheri, Anahid Safari, Mohammad Reza Namavar · 2021 · Behavioural Brain Research
- Maternal infection during pregnancy aggravates the behavioral response to an immune challenge during adolescence in female ratsCyprien G.J. Guerrin, Erik F. J. de Vries, Kavya Prasad, Daniel Aaron Vazquez-Matias, Lesley E. Manusiwa, Lara Barazzuol, Janine Doorduin · 2023 · Behavioural Brain Research
- Towards an Integrated View of Early Molecular Changes Underlying Vulnerability to Social Stress in PsychosisHenry Barron, Sina Hafizi, Romina Mizrahi · 2017 · Modern trends in psychiatry
- Neuroinflammation and Microglial Activation in Schizophrenia: An OverviewNourhan Shebl · 2023 · Springer eBooks
- Anti-SFT2D2 autoantibodies alter dendrite spine and cause psychotic behavior in miceDuilin Liu, Zhongman Jin, Hui Wei, Caiyun Zhu, Kejiang Liu, Pengsheng You, Jiahang Ju, Jinming Xu, Wanwan Zhu, Qi Xu · 2024 · Journal of Psychiatric Research
- Redox and Microglia in the Pathophysiology of SchizophreniaTakahiro A. Kato, Fuminori Hyodo, Mayumi Yamato, Hideo Utsumi, Shigenobu Kanba · 2015 · YAKUGAKU ZASSHI
- Schizophrenia: from mechanism to therapyZhe Lu, Junyuan Sun, Guorui Zhao, Yunqing Zhu, Rui Yuan, Jingying Zhou, Dai Zhang, Weihua Yue · 2026 · Science China Life Sciences
- Evolutionary Perspectives on Schizophrenia Spectrum DisordersMartin Brüne · 2022 · Cambridge University Press eBooks
- Effect of Electroconvulsive Therapy (ECT) on IL-1β, IP-10, IL-17, TNFα, IL-10 and Soluble IL-2 Receptor in Treatment-Resistant Schizophrenia (TRS) Patients—A Preliminary StudyAnna Maria Szota, Małgorzata M. Ćwiklińska-Jurkowska, Izabela Radajewska, Kinga Lis, Przemysław Grudzka, W. Dróżdż · 2025 · Journal of Clinical Medicine
- The Question of Pro-Inflammatory Immune Activity in Schizophrenia and the Potential Importance of Anti-Inflammatory DrugsVolker Arolt, Oliver Ambrée · 2013 · Modern trends in psychiatry
- Characterisation of the consequences of maternal immune activation on distinct cell populations in the developing rat spinal cordRebecca Cogwell Anderson, Gerard W. O’Keeffe, Kieran W.G. McDermott · 2022 · Journal of Anatomy
- Neurodevelopmental and Neuropsychiatric DisordersAkira Monji, Izumi Maezawa, Yoshito Mizoguchi, Takahiro A. Kato, Lee‐Way Jin · 2014 · Springer eBooks
- Editorial: Minding Glial Cells in the Novel Understandings of Mental IllnessTakahiro A. Kato, Aye-Mu Myint, Johann Steiner · 2017 · Frontiers in Cellular Neuroscience
- Aflatoxin B1 exposure deteriorates immune abnormalities in a BTBR T+ Itpr3tf/J mouse model of autism by increasing inflammatory mediators' production in CD19-expressing cellsTaghreed N. Almanaa, Mohammad Y. Alwetaid, Saleh A. Bakheet, Sabry Mohamed Attia, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sheikh F. Ahmad · 2024 · Journal of Neuroimmunology
- Pioglitazone attenuates behavioral and electrophysiological dysfunctions induced by two-hit model of schizophrenia in adult rodent offspringA. B. Sonego, Douglas S. Prado, D. Uliana, Thiago M. Cunha, Anthony A. Grace, L. Resstel · 2024 · European Neuropsychopharmacology
- Maternal Immune Activation and Neuropsychiatric Disorders: The Intricate Puzzle of Autism Spectrum DisorderMellanie Fontes‐Dutra, Bruna Frizzo Rabelo, Júlio Santos‐Terra, Iohanna Deckmann, Gustavo Brum Schwingel, Carmem Gottfried · 2020 · Progress in inflammation research
- Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implicationsMadeleine Nussbaumer, Paul C. Guest, Kolja Schiltz, Leon Dudeck, Leila Shokati Asl, Gabriela Meyer-Lotz, Henrik Dobrowolny, Stefan Leucht, Hans‐Gert Bernstein, Thomas Nickl‐Jockschat et al. · 2026 · Molecular Psychiatry
- Vagus nerve stimulation as an anti-inflammatory therapy for maternal immune activation-induced alterations in offspring microglia and neurodevelopmentMakenna Gargus, Linnea Poyhia, Joseph P. Errico, M. Karen Newell Rogers, Marie‐Ève Tremblay · 2026 · Frontiers in Neuroscience
- Maternal Immune Activation as a Risk Factor for Schizophrenia: Evidence From Preclinical and Clinical StudiesCamila Nayane de Carvalho Lima, Tejaswini Doifode, Allan Colodel, Pavani Sayana, Vijayasree Vayalanellore Giridharan, Danielle S. Macêdo, Omar F. Pinjari, Tatiana Barichello · 2020 · Progress in inflammation research
- Immune Involvement in Autism Spectrum Disorder as a Basis for Animal ModelsElaine Y. Hsiao · 2012 · Autism - Open Access
- Explorando o componente inflamatório da esquizofreniaHassan Rahmoune, W. Harris, Paul C. Guest, Sabine Bahn · 2012 · Archives of Clinical Psychiatry (São Paulo)
- Neuroinflammation and neuroprotection in schizophrenia and autism spectrum disorderEhud Mekori‐Domachevsky, Hadar Segal‐Gavish, Raz Gross · 2019 · Elsevier eBooks
- Sex specific correction of maternal inflammation-induced behavioral abnormalities by the inhibition of colony-stimulating factor 1 receptorJean-Christophe Delpech, Hana Yeh, Srinidhi Venkatesan Kalavai, Yang You, Zhi Ruan, Nina Touch, Samuel Walter Hersh, Pauline Monguillon, William Evan Johnson, Andréa Rau et al. · 2025 · Brain Behavior and Immunity
- Animal Models Based on Immune Challenge: The Link to Brain Changes and SchizophreniaGeorg Juckel · 2015 · Current topics in neurotoxicity
- Inflammational Animal Models for SchizophreniaGeorg Juckel · 2015 · Zeitschrift für Psychologie
- Neuroinflammation and Microglial Activation in Schizophrenia: An OverviewNourhan Shebl · 2024 · Springer eBooks
- Malaria in Pregnancy: An Unrecognized Risk Factor for Neuropsychiatric Disease in Offspring?Vanessa Tran, Andrea M. Weckman, Kevin C. Kain · 2016 · Pediatric Infectious Diseases Open Access
- TLR2 genetic diversity associated with the risk of Schizophrenia development in a Tunisian populationFayza Ayari, Arij Ben Chaaben, Hajer Abbaza, Ons Mihoub, Nesrine Ouni, Amani Mankaï, Wahid Boukouaci, Maher kharat, Marion Leboyer, Ryad Tamouza · 2022 · Research Square
- Inflammation and immune-mediated neurobehavioral alterations : a critical role for microgliaChloé Lacabanne · 2018 · theses.fr (ABES)
- Mild Encephalitis Theory of Psychiatric DisordersKarl Bechter · 2015 · Current topics in neurotoxicity
- Characterization of a rat model of Maternal Immune Activation with relevance to schizophrenia in terms of maternal and foetal cytokine responses, adult behavioural outcome and chronic brain inflammationStephan Missault · 2013
- Microglial Abnormalities in the Pathophysiology ofSchizophrenia Monji, Yoshito Mizoguchi, Takahiro A. Kato · 2014
- Quantitative Evaluation of Microglial Activation and Vascularization in SuicideTatiana P. Schnieder · 2014 · CUNY Academic Works (City University of New York)
- Developmental Neuroimmune Mechanisms in SchizophreniaUlrike Weber‐Stadlbauer, Urs Meyer · 2015 · Royal Society of Chemistry eBooks
- Antidepressants Modulate Microglia Beyond the Neurotransmitters Doctrine of Mood DisordersMasahiro Ohgidani, Takahiro A. Kato, Yoshito Mizoguchi, Hideki Horikawa, Akira Monji, Shigenobu Kanba · 2016 · Springer eBooks
- Neuroinflammation and psychosis; antipsychotic medication.Peter S. Bloomfield · 2015 · Spiral (Imperial College London)
- Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activitySM Brown, Stephen J. Bush, KIM M. SUMMERS, DA Hume, AB Lawrence · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Psychiatric DisordersJosef Priller · 2012 · Oxford University Press eBooks
- TLR2 genetic diversity and the risk of SchizophreniaFayza Ayari, Arij Ben Chaaben, Hajer Abbaza, Ons Mihoub, Nesrine Ouni, Amani Mankaï, Wahid Boukouaci, Maher kharat, Marion Leboyer, Ryad Tamouza · 2022 · Research Square
- A novel miR-99b-5p- Zbp1 pathway in microglia contributes to the pathogenesis of schizophreniaLalit Kaurani, Rezaul Islam, Urs Heilbronner, Dennis M. Krüger, Jiayin Zhou, Aditi Methi, Judith Strauß, Ranjit Pradhan, Susanne Burkhardt, Tonatiuh Peña et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Suppression of microglial activation with anti-inflammatory drug bindarit enhances neural development in the shunt-treated neonatal hydrocephalus model ratEri Iwasawa, Farrah N. Brown, Crystal Shula, A. Scott Emmert, Elizabeth M. Fugate, Diana M. Lindquist, Francesco T. Mangano, June Goto · 2025 · Experimental Neurology
- Deep Brain Stimulation Modulates Nucleus Accumbens Theta-Band Power in a Rodent Model of SchizophreniaNadja Freund, Patrick R. Reinhardt, Mate Abraham, Klaus Funke, Georg Juckel · 2026 · Brain Sciences
- Adolescent Exposure to a THC ‐Rich Cannabis Extract Produces Genotype‐Dependent Effects on Cognition and Glial Morphology in Serine Racemase Mutant MiceIgor F. Rangel, Melissa Chaves, Iohanna Bianca Pagnoncelli, Isabelle Medeiros, Felipe Pinheiro, Lorena Fortuna da Silva, Luiza A. Castello Branco, Ernesto Díaz Rocha, Virgínia Martins Carvalho, Flávia Regina Souza Lima et al. · 2026 · Journal of Neurochemistry
- Peripheral S100B, Cell-Free DNA, and Circulating RNA Biomarkers in Psychotic Disorders: A Systematic Review of Schizophrenia-Spectrum Findings and Primary–Secondary ComparisonsSergey A. Yuchshuk, Aleksei B. Ilichev, Olga Anatolyevna Ponamareva, Marina Yu. Lyubchenko, Dana S. Shaymerdenova, Tatyana Aleksandrovna Stupina, Lola A. Mekhraliyeva, Alina S. Yakovleva, Aidana K. Kenzhegulova, Natalia N. Shutilina et al. · 2026 · Biomedicines