Microglial activation in a neuroinflammational animal model of schizophrenia – a pilot study

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Items 101–165 of 165

  1. Psychopharmacological Treatment of Neurocognitive Deficits in People with Schizophrenia: A Review of Old and New Targets
    Anthony O. Ahmed, Ishrat Bhat · 2014 · CNS Drugs
  2. Oxidative stress and schizophrenia: A comparative cross‐sectional study of multiple oxidative markers in patients and their first‐degree relatives
    Eray Metin Güler, Ayşe Kurtulmuş, Ayşe Zehra Gül, Abdürrahim Koçyiğit, İsmet Kırpınar · 2021 · International Journal of Clinical Practice
  3. Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice
    Kaurani, Lalit, Islam, Md Rezaul, Heilbronner, Urs, Krüger, Dennis M, Zhou, Jiayin, Methi, Aditi, Strauss, Judith, Pradhan, Ranjit, Schröder, Sophie, Burkhardt, Susanne et al. · 2024 · The EMBO Journal
  4. Recent advances in psychoneuroimmunology relevant to schizophrenia therapeutics
    Monojit Debnath, Ganesan Venkatasubramanian · 2013 · Current Opinion in Psychiatry
  5. Neuroinflammatory Loop in Schizophrenia, Is There a Relationship with Symptoms or Cognition Decline?
    Claudio Carril Pardo, Karina Oyarce, América Vera-Montecinos · 2025 · International Journal of Molecular Sciences
  6. Characterizing the neuroimmune environment of offspring in a novel model of maternal allergic asthma and particulate matter exposure
    Juan M. Tamayo, Hadley C. Osman, Jared J. Schwartzer, Kent E. Pinkerton, Paul Ashwood · 2023 · Journal of Neuroinflammation
  7. Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental challenge
    Micaël Carrier, Chin Wai Hui, Valérie Watters, Eva Šimončičová, Katherine Picard, Fernando Gonzàlez Ibáñez, Nathalie Vernoux, Arnaud Droit, Michèle Desjardins, Marie‐Ève Tremblay · 2023 · Brain Behavior and Immunity
  8. Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation
    Khalil, Omari S., Forrest, Caroline M., Pisar, Mazura, Smith, Robert A., Darlington, L. Gail, Stone, Trevor W. · 2013 · Immunopharmacology and Immunotoxicology
  9. Antipsychotic-like effect of minocycline in a rat model.
    Recep Dokuyucu, Mehmet Hanifi Kokaçya, Sema İnanır, Ümit Sertan Çöpoğlu, Oytun Erbaş · 2014 · PubMed Central
  10. Poly I:C‐induced maternal immune challenge reduces perineuronal net area and raises spontaneous network activity of hippocampal neurons in vitro
    David Wegrzyn, Marie Pierre Manitz, Michael Kostka, Nadja Freund, Georg Juckel, Andréas Faissner · 2020 · European Journal of Neuroscience
  11. The implications of hypothalamic abnormalities for schizophrenia
    Hans‐Gert Bernstein, Gerburg Keilhoff, Johann Steiner · 2021 · Handbook of clinical neurology
  12. Cannabinoid receptor type 2 gene is associated with comorbidity of schizophrenia and cannabis dependence and fatty acid amide hydrolase gene is associated with cannabis dependence in the Spanish population
    F. Árias, José Ramón Dávila Píriz, Alba Parra, Sergio Sánchez Romero, Eva María Sánchez‐Morla, Israel Ampuero, José Antonio Ramos Atance · 2021 · Adicciones
  13. Emotional Contagion is not Altered in Mice Prenatally Exposed to Poly (I:C) on Gestational Day 9
    Cristina Gonzalez-Liencres, Georg Juckel, Manuela Eßlinger, Simone Wachholz, Marie Pierre Manitz, Martin Brüne, Astrid Friebe · 2016 · Frontiers in Behavioral Neuroscience
  14. Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspring
    Ryan J. Duchatel, Crystal L. Meehan, Lauren R. Harms, Patricia Therese Michie, Mark J. Bigland, Doug William Smith, Frederick Rohan Walker, Phillip Jobling, Deborah M. Hodgson, Paul A. Tooney · 2018 · Psychiatry Research
  15. CNS Macrophages and Infant Infections
    Alexander Oschwald, Philippe Petry, Katrin Kierdorf, Daniel Erny · 2020 · Frontiers in Immunology
  16. Commentary: Maternal immune activation evoked by polyinosinic: polycytidylic acid does not evoke microglial cell activation in the embryo
    Hans‐Gert Bernstein, Yael Piontkewitz, Gerburg Keilhoff · 2016 · Frontiers in Cellular Neuroscience
  17. Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophrenia
    Anna M. Fiorito, Éric Fakra, Guillaume Sescousse, El Chérif Ibrahim, Romain Rey · 2023 · Translational Psychiatry
  18. A Weighted Gene Co-expression Network Analysis Reveals lncRNA Abnormalities in the Peripheral Blood Associated With Ultra-High-Risk for Psychosis
    Yan Xin Ren, Wei Li, Sha Liu, Zhi Li, Jiaying Wang, Hong Yang, Yong Ji Xu · 2020 · Frontiers in Psychiatry
  19. Interleukin-6 produces behavioral deficits in pre-pubescent mice independent of neuroinflammation
    Fernando Janczur Velloso, Rebecca Zaritsky, Rouba Y. Houbeika, Nicolas Rios, Steven W. Levison · 2025 · Brain Behavior and Immunity
  20. Neuroimmune and behavioral changes elicited by maternal immune activation in mice are ameliorated by early postnatal immune stimulation
    Lourdes K. Davis, Louise Madeleine Ince, Sriya Gullapalli, Laura K. Fonken · 2025 · Brain Behavior and Immunity
  21. Microglia and microbiome in schizophrenia: can immunomodulation improve symptoms?
    Georg Juckel, Nadja Freund · 2023 · Journal of Neural Transmission
  22. Effect of dimethyl fumarate on the changes in the medial prefrontal cortex structure and behavior in the poly(I:C)-induced maternal immune activation model of schizophrenia in the male mice
    Farshid Bagheri, Anahid Safari, Mohammad Reza Namavar · 2021 · Behavioural Brain Research
  23. Maternal infection during pregnancy aggravates the behavioral response to an immune challenge during adolescence in female rats
    Cyprien G.J. Guerrin, Erik F. J. de Vries, Kavya Prasad, Daniel Aaron Vazquez-Matias, Lesley E. Manusiwa, Lara Barazzuol, Janine Doorduin · 2023 · Behavioural Brain Research
  24. Towards an Integrated View of Early Molecular Changes Underlying Vulnerability to Social Stress in Psychosis
    Henry Barron, Sina Hafizi, Romina Mizrahi · 2017 · Modern trends in psychiatry
  25. Neuroinflammation and Microglial Activation in Schizophrenia: An Overview
    Nourhan Shebl · 2023 · Springer eBooks
  26. Anti-SFT2D2 autoantibodies alter dendrite spine and cause psychotic behavior in mice
    Duilin Liu, Zhongman Jin, Hui Wei, Caiyun Zhu, Kejiang Liu, Pengsheng You, Jiahang Ju, Jinming Xu, Wanwan Zhu, Qi Xu · 2024 · Journal of Psychiatric Research
  27. Redox and Microglia in the Pathophysiology of Schizophrenia
    Takahiro A. Kato, Fuminori Hyodo, Mayumi Yamato, Hideo Utsumi, Shigenobu Kanba · 2015 · YAKUGAKU ZASSHI
  28. Schizophrenia: from mechanism to therapy
    Zhe Lu, Junyuan Sun, Guorui Zhao, Yunqing Zhu, Rui Yuan, Jingying Zhou, Dai Zhang, Weihua Yue · 2026 · Science China Life Sciences
  29. Evolutionary Perspectives on Schizophrenia Spectrum Disorders
    Martin Brüne · 2022 · Cambridge University Press eBooks
  30. Effect of Electroconvulsive Therapy (ECT) on IL-1β, IP-10, IL-17, TNFα, IL-10 and Soluble IL-2 Receptor in Treatment-Resistant Schizophrenia (TRS) Patients—A Preliminary Study
    Anna Maria Szota, Małgorzata M. Ćwiklińska-Jurkowska, Izabela Radajewska, Kinga Lis, Przemysław Grudzka, W. Dróżdż · 2025 · Journal of Clinical Medicine
  31. The Question of Pro-Inflammatory Immune Activity in Schizophrenia and the Potential Importance of Anti-Inflammatory Drugs
    Volker Arolt, Oliver Ambrée · 2013 · Modern trends in psychiatry
  32. Characterisation of the consequences of maternal immune activation on distinct cell populations in the developing rat spinal cord
    Rebecca Cogwell Anderson, Gerard W. O’Keeffe, Kieran W.G. McDermott · 2022 · Journal of Anatomy
  33. Neurodevelopmental and Neuropsychiatric Disorders
    Akira Monji, Izumi Maezawa, Yoshito Mizoguchi, Takahiro A. Kato, Lee‐Way Jin · 2014 · Springer eBooks
  34. Editorial: Minding Glial Cells in the Novel Understandings of Mental Illness
    Takahiro A. Kato, Aye-Mu Myint, Johann Steiner · 2017 · Frontiers in Cellular Neuroscience
  35. Aflatoxin B1 exposure deteriorates immune abnormalities in a BTBR T+ Itpr3tf/J mouse model of autism by increasing inflammatory mediators' production in CD19-expressing cells
    Taghreed N. Almanaa, Mohammad Y. Alwetaid, Saleh A. Bakheet, Sabry Mohamed Attia, Mushtaq Ahmad Ansari, Ahmed Nadeem, Sheikh F. Ahmad · 2024 · Journal of Neuroimmunology
  36. Pioglitazone attenuates behavioral and electrophysiological dysfunctions induced by two-hit model of schizophrenia in adult rodent offspring
    A. B. Sonego, Douglas S. Prado, D. Uliana, Thiago M. Cunha, Anthony A. Grace, L. Resstel · 2024 · European Neuropsychopharmacology
  37. Maternal Immune Activation and Neuropsychiatric Disorders: The Intricate Puzzle of Autism Spectrum Disorder
    Mellanie Fontes‐Dutra, Bruna Frizzo Rabelo, Júlio Santos‐Terra, Iohanna Deckmann, Gustavo Brum Schwingel, Carmem Gottfried · 2020 · Progress in inflammation research
  38. Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implications
    Madeleine Nussbaumer, Paul C. Guest, Kolja Schiltz, Leon Dudeck, Leila Shokati Asl, Gabriela Meyer-Lotz, Henrik Dobrowolny, Stefan Leucht, Hans‐Gert Bernstein, Thomas Nickl‐Jockschat et al. · 2026 · Molecular Psychiatry
  39. Vagus nerve stimulation as an anti-inflammatory therapy for maternal immune activation-induced alterations in offspring microglia and neurodevelopment
    Makenna Gargus, Linnea Poyhia, Joseph P. Errico, M. Karen Newell Rogers, Marie‐Ève Tremblay · 2026 · Frontiers in Neuroscience
  40. Maternal Immune Activation as a Risk Factor for Schizophrenia: Evidence From Preclinical and Clinical Studies
    Camila Nayane de Carvalho Lima, Tejaswini Doifode, Allan Colodel, Pavani Sayana, Vijayasree Vayalanellore Giridharan, Danielle S. Macêdo, Omar F. Pinjari, Tatiana Barichello · 2020 · Progress in inflammation research
  41. Immune Involvement in Autism Spectrum Disorder as a Basis for Animal Models
    Elaine Y. Hsiao · 2012 · Autism - Open Access
  42. Explorando o componente inflamatório da esquizofrenia
    Hassan Rahmoune, W. Harris, Paul C. Guest, Sabine Bahn · 2012 · Archives of Clinical Psychiatry (São Paulo)
  43. Neuroinflammation and neuroprotection in schizophrenia and autism spectrum disorder
    Ehud Mekori‐Domachevsky, Hadar Segal‐Gavish, Raz Gross · 2019 · Elsevier eBooks
  44. Sex specific correction of maternal inflammation-induced behavioral abnormalities by the inhibition of colony-stimulating factor 1 receptor
    Jean-Christophe Delpech, Hana Yeh, Srinidhi Venkatesan Kalavai, Yang You, Zhi Ruan, Nina Touch, Samuel Walter Hersh, Pauline Monguillon, William Evan Johnson, Andréa Rau et al. · 2025 · Brain Behavior and Immunity
  45. Animal Models Based on Immune Challenge: The Link to Brain Changes and Schizophrenia
    Georg Juckel · 2015 · Current topics in neurotoxicity
  46. Inflammational Animal Models for Schizophrenia
    Georg Juckel · 2015 · Zeitschrift für Psychologie
  47. Neuroinflammation and Microglial Activation in Schizophrenia: An Overview
    Nourhan Shebl · 2024 · Springer eBooks
  48. Malaria in Pregnancy: An Unrecognized Risk Factor for Neuropsychiatric Disease in Offspring?
    Vanessa Tran, Andrea M. Weckman, Kevin C. Kain · 2016 · Pediatric Infectious Diseases Open Access
  49. TLR2 genetic diversity associated with the risk of Schizophrenia development in a Tunisian population
    Fayza Ayari, Arij Ben Chaaben, Hajer Abbaza, Ons Mihoub, Nesrine Ouni, Amani Mankaï, Wahid Boukouaci, Maher kharat, Marion Leboyer, Ryad Tamouza · 2022 · Research Square
  50. Inflammation and immune-mediated neurobehavioral alterations : a critical role for microglia
    Chloé Lacabanne · 2018 · theses.fr (ABES)
  51. Mild Encephalitis Theory of Psychiatric Disorders
    Karl Bechter · 2015 · Current topics in neurotoxicity
  52. Characterization of a rat model of Maternal Immune Activation with relevance to schizophrenia in terms of maternal and foetal cytokine responses, adult behavioural outcome and chronic brain inflammation
    Stephan Missault · 2013
  53. Microglial Abnormalities in the Pathophysiology of
    Schizophrenia Monji, Yoshito Mizoguchi, Takahiro A. Kato · 2014
  54. Quantitative Evaluation of Microglial Activation and Vascularization in Suicide
    Tatiana P. Schnieder · 2014 · CUNY Academic Works (City University of New York)
  55. Developmental Neuroimmune Mechanisms in Schizophrenia
    Ulrike Weber‐Stadlbauer, Urs Meyer · 2015 · Royal Society of Chemistry eBooks
  56. Antidepressants Modulate Microglia Beyond the Neurotransmitters Doctrine of Mood Disorders
    Masahiro Ohgidani, Takahiro A. Kato, Yoshito Mizoguchi, Hideki Horikawa, Akira Monji, Shigenobu Kanba · 2016 · Springer eBooks
  57. Neuroinflammation and psychosis; antipsychotic medication.
    Peter S. Bloomfield · 2015 · Spiral (Imperial College London)
  58. Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity
    SM Brown, Stephen J. Bush, KIM M. SUMMERS, DA Hume, AB Lawrence · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Psychiatric Disorders
    Josef Priller · 2012 · Oxford University Press eBooks
  60. TLR2 genetic diversity and the risk of Schizophrenia
    Fayza Ayari, Arij Ben Chaaben, Hajer Abbaza, Ons Mihoub, Nesrine Ouni, Amani Mankaï, Wahid Boukouaci, Maher kharat, Marion Leboyer, Ryad Tamouza · 2022 · Research Square
  61. A novel miR-99b-5p- Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia
    Lalit Kaurani, Rezaul Islam, Urs Heilbronner, Dennis M. Krüger, Jiayin Zhou, Aditi Methi, Judith Strauß, Ranjit Pradhan, Susanne Burkhardt, Tonatiuh Peña et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Suppression of microglial activation with anti-inflammatory drug bindarit enhances neural development in the shunt-treated neonatal hydrocephalus model rat
    Eri Iwasawa, Farrah N. Brown, Crystal Shula, A. Scott Emmert, Elizabeth M. Fugate, Diana M. Lindquist, Francesco T. Mangano, June Goto · 2025 · Experimental Neurology
  63. Deep Brain Stimulation Modulates Nucleus Accumbens Theta-Band Power in a Rodent Model of Schizophrenia
    Nadja Freund, Patrick R. Reinhardt, Mate Abraham, Klaus Funke, Georg Juckel · 2026 · Brain Sciences
  64. Adolescent Exposure to a THC ‐Rich Cannabis Extract Produces Genotype‐Dependent Effects on Cognition and Glial Morphology in Serine Racemase Mutant Mice
    Igor F. Rangel, Melissa Chaves, Iohanna Bianca Pagnoncelli, Isabelle Medeiros, Felipe Pinheiro, Lorena Fortuna da Silva, Luiza A. Castello Branco, Ernesto Díaz Rocha, Virgínia Martins Carvalho, Flávia Regina Souza Lima et al. · 2026 · Journal of Neurochemistry
  65. Peripheral S100B, Cell-Free DNA, and Circulating RNA Biomarkers in Psychotic Disorders: A Systematic Review of Schizophrenia-Spectrum Findings and Primary–Secondary Comparisons
    Sergey A. Yuchshuk, Aleksei B. Ilichev, Olga Anatolyevna Ponamareva, Marina Yu. Lyubchenko, Dana S. Shaymerdenova, Tatyana Aleksandrovna Stupina, Lola A. Mekhraliyeva, Alina S. Yakovleva, Aidana K. Kenzhegulova, Natalia N. Shutilina et al. · 2026 · Biomedicines