Cited by 17

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Transcriptome analysis of human induced excitatory neurons supports a strong effect of clozapine on cholesterol biosynthesis

Das, Debamitra, Peng, Xi, Lam, Anh-Thu N., Bader, Joel S., Avramopoulos, Dimitrios·2021·Schizophrenia Research

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Crossref · 10.1016/j.schres.2020.12.041

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Research works printed but not linked: 13

  1. Aringhieri, 2018, Molecular targets of atypical antipsychotics: from mechanism of action to clinical differences, Pharmacol. Ther., 192, 20, 10.1016/j.pharmthera.2018.06.012 · DOI
  2. Bae, 1997, Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol delta 24-reductase, Biochem. J., 326, 609, 10.1042/bj3260609 · DOI
  3. Das, 2020, Modeling psychiatric disorder biology with stem cells, Curr. Psychiatry Rep., 22, 24, 10.1007/s11920-020-01148-1 · DOI
  4. Ferno, 2005, Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?, Pharm. J., 5, 298
  5. Jin, 2019, Cholesterol metabolism in the brain and its association with Parkinson’s disease, Exp. Neurobiol., 28, 554, 10.5607/en.2019.28.5.554 · DOI · Paper page
  6. Lijnen, 1997, The effect of membrane cholesterol content on ion transport processes in plasma membranes, Cardiovasc. Res., 35, 384
  7. Pfrieger, 2003, Role of cholesterol in synapse formation and function, Biochim. Biophys. Acta, 1610, 271, 10.1016/S0005-2736(03)00024-5 · DOI · Paper page
  8. Schmitz, 2001, Intracellular cholesterol and phospholipid trafficking: comparable mechanisms in macrophages and neuronal cells, Neurochem. Res., 26, 1045, 10.1023/A:1012357106398 · DOI
  9. Sirtori, 2014, The pharmacology of statins, Pharmacol. Res., 88, 3, 10.1016/j.phrs.2014.03.002 · DOI
  10. Tierney, 2001, Behavior phenotype in the RSH/Smith-Lemli-Opitz syndrome, Am. J. Med. Genet., 98, 191, 10.1002/1096-8628(20010115)98:2<191::AID-AJMG1030>3.0.CO;2-M · DOI
  11. Vik-Mo, 2009, Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells, BMC Pharmacol., 9, 10, 10.1186/1471-2210-9-10 · DOI
  12. Zhang, 2015, Cholesterol metabolism and homeostasis in the brain, Protein Cell., 6, 254, 10.1007/s13238-014-0131-3 · DOI · Paper page
  13. Zhang, 2013, Rapid single-step induction of functional neurons from human pluripotent stem cells, Neuron, 78, 785, 10.1016/j.neuron.2013.05.029 · DOI · Paper page

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Metadata

Authors
Das, D., Peng, X., Lam, A.-T. N., Bader, J. S., & Avramopoulos, D.
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2021-02
Volume
228
Pages
324-326
ISSN
0920-9964
Cited by
17
References
4
Language
en
Funders
National Institute of Mental Health (P50 MH094268, R01 MH113215, RF1 MH122936)

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