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Early exposure to sunlight and allergic morbidity: The PARIS birth cohort
Open accessAbstract
The relationship between sunlight and allergies in children has received limited attention from researchers. We sought to explore how early exposure to solar radiation is associated with allergic morbidity within the PARIS birth cohort study. Our research dealt with children who attended at least one of two health checkups: at 18 months (n = 2012) and at 8-9 years (n = 1080). Early exposure to solar radiation was assessed using meteorological data (e.g., solar radiation, temperature, and relative humidity). Children with similar meteorological exposure trajectories were grouped by a longitudinal and multidimensional cluster analysis. The association between solar radiation exposure and allergic morbidity (i.e., allergic sensitization at 18 months and 8-9 years; current asthma, rhinitis, and eczema at 8-9 years) was quantified by multivariable logistic regression models adjusted for potential confounders. The effect modification of maternal vitamin D supplementation during pregnancy was tested. Four meteorological exposure trajectories were found. The trajectory with the highest exposure to early solar radiation had a reduced risk of sensitization at 8-9 years compared to the trajectory with the lowest exposure (p = 0.06). The association was statistically significant in the vitamin D supplementation group. Solar radiation during prenatal and postnatal periods was significantly associated with a lower risk of sensitization at 8-9 years (for one interquartile range (IQR) increase, adjusted odds ratio (aOR): 0.47; 95 % confidence interval (CI): 0.25-0.87 and 0.84; 0.7-1.00, respectively). Increased prenatal exposure to solar radiation was significantly associated with a lower risk of asthma at 8-9 years (for one IQR increase, aOR: 0.32; 95 % CI: 0.1-0.96). Early sunlight exposure may reduce the risk of sensitization and asthma in school-aged children, especially in those prenatally exposed to vitamin D. These findings highlight the importance of vitamin D in preventing allergic diseases in children, either through supplementation or sunlight exposure.
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“There was evidence that higher ambient solar radiation during pregnancy and the first year of life was associated with reduced allergen sensitisation at 8–9 years of age [e.g., the odds ratio for sensitisation to at least one inhalant allergen per one interquartile range increase in radiation was 0.49 (95% confidence interval 0.27–0.87)].”
In the citing paper
“There was a stronger association with prenatal maternal exposure than with postnatal exposure of the infant.”
In the citing paper
“The effects were most evident in children whose mothers had been supplemented with vitamin D during pregnancy, suggesting possible synergy between exposure to solar radiation and vitamin D.”
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Pinart, M., Benet, M., Annesi-Maesano, I., von Berg, A., Berdel, D., Carlsen, K. C. L., Carlsen, K.-H., Bindslev-Jensen, C., Eller, E., Fantini, M. P., et al. (2014) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(13)70277-7 · Cited by 334
Self-citationPhotoimmunology: how ultraviolet radiation affects the immune system
Bernard, J. J., Gallo, R. L., & Krutmann, J. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0185-9 · Cited by 329
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Research works printed but not linked: 29
- Almqvist, 2020, Season of birth, childhood asthma and allergy in a nationwide cohort-mediation through lower respiratory infections, Clinical and Experimental Allergy, 50, 222, 10.1111/cea.13542 · DOI
- Arnedo-Pena, 2011, Sunny hours and variations in the prevalence of asthma in schoolchildren according to the international study of asthma and allergies (ISAAC) phase III in Spain, International journal of biometeorology, 55, 423, 10.1007/s00484-010-0353-x · DOI
- Arnedo-Pena, 2013, Prevalence of asthma symptoms in schoolchildren, and climate in west European countries: an ecologic study, Int. J. Biometeorol., 57, 775, 10.1007/s00484-012-0606-y · DOI
- Asher, 1995, International study of asthma and allergies in childhood (ISAAC): rationale and methods, The European Respiratory Journal, 8, 483, 10.1183/09031936.95.08030483 · DOI · Paper page
- Asher, 2012, Changes over time in the relationship between symptoms of asthma, rhinoconjunctivitis and eczema: a global perspective from the International Study of Asthma and Allergies in Childhood (ISAAC), Allergol. Immunopathol., 40, 267, 10.1016/j.aller.2011.11.004 · DOI
- Bougas, 2018, Traffic-related air pollution, lung function, and host vulnerability, New Insights from the PARIS Birth Cohort. Ann Am Thorac Soc., 15, 599
- Clarisse, 2007, The Paris prospective birth cohort study: which design and who participates?, Eur. J. Epidemiol., 22, 203, 10.1007/s10654-007-9109-2 · DOI
- Cyprian, 2019, Immunomodulatory effects of Vitamin D in pregnancy and beyond, Front. Immunol., 10, 2739, 10.3389/fimmu.2019.02739 · DOI
- D’Amato, 2015, Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the world allergy organization, The World Allergy Organization Journal., 8(1):25
- Gillman, 2005, Developmental origins of health and disease, N. Engl. J. Med., 353, 1848, 10.1056/NEJMe058187 · DOI
- Holick, 2007, Vitamin D Deficiency, N. Engl. J. Med., 357, 266, 10.1056/NEJMra070553 · DOI · Paper page
- Hornsby, 2018, Vitamin D supplementation during pregnancy: effect on the neonatal immune system in a randomized controlled trial, The Journal of Allergy and Clinical Immunology, 141, 269, 10.1016/j.jaci.2017.02.039 · DOI
- Hoyos-Bachiloglu, 2014, Higher latitude and lower solar radiation influence on anaphylaxis in Chilean children, Pediatric Allergy and Immunology, 25, 338, 10.1111/pai.12211 · DOI
- Hwang, 2016, The relationships among birth season, sunlight exposure during infancy, and allergic disease, Korean J. Pediatr., 59, 218, 10.3345/kjp.2016.59.5.218 · DOI
- Kemp, 2013, The influence of sun exposure in childhood and adolescence on atopic disease at adolescence, Pediatr. Allergy Immunol., 24, 493, 10.1111/pai.12085 · DOI
- Koh, 2018, Exposure amount and timing of solar irradiation during pregnancy and the risk of sensitization in children, Allergol. Int., 67, 225, 10.1016/j.alit.2017.08.007 · DOI
- Kuzume, 2007, Before-birth climatologic data may play a role in the development of allergies in infants, Pediatric Allergy and Immunology, 18, 281, 10.1111/j.1399-3038.2006.00526.x · DOI
- Li, 2019, Vitamin D supplementation during pregnancy and the risk of wheezing in offspring: a systematic review and dose-response meta-analysis, The Journal of Asthma: Official Journal of the Association for the Care of Asthma, 56, 1266, 10.1080/02770903.2018.1536142 · DOI
- Matsui, 2015, Sun exposure inversely related to food sensitization during infancy, Pediatr. Allergy Immunol., 26, 628, 10.1111/pai.12445 · DOI
- Molloy, 2017, Vitamin D insufficiency in the first 6 months of infancy and challenge-proven IgE-mediated food allergy at 1 year of age: a case-cohort study, Allergy, 72, 1222, 10.1111/all.13122 · DOI
- Mullins, 2009, Regional variation in epinephrine autoinjector prescriptions in Australia: more evidence for the vitamin D-anaphylaxis hypothesis, 103(6), 488
- Pearce, 2007, Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC), Thorax, 62, 758, 10.1136/thx.2006.070169 · DOI
- Rudders, 2010, North-south differences in US emergency department visits for acute allergic reactions, Ann. Allergy Asthma Immunol., 104, 413, 10.1016/j.anai.2010.01.022 · DOI
- Rueter, 2021, The influence of sunlight exposure and sun protecting Behaviours on allergic outcomes in early childhood, Int. J. Environ. Res. Public Health, 18(10):5429
- Susanto, 2017, Effect of season of birth on cord blood IgE and IgE at birth: a systematic review and meta-analysis, Environmental Research, 157, 198, 10.1016/j.envres.2017.05.026 · DOI
- Vassallo, 2010, Season of birth and food allergy in children, Annals of Allergy Asthma & Immunology, 104, 307, 10.1016/j.anai.2010.01.019 · DOI
- Wu, 2008, Evidence of a causal role of winter virus infection during infancy in early childhood asthma, Am. J. Respir. Crit. Care Med., 178, 1123, 10.1164/rccm.200804-579OC · DOI
- Yokomichi, 2021, Association of the incidence of atopic dermatitis until 3 years old with birth month and with sunshine duration and humidity in the first 6 months of life: Japan environment and children’s study, BMJ Open, 11, 10.1136/bmjopen-2020-047226 · DOI
- Zhang, 2016, Air pollutants, climate, and the prevalence of pediatric asthma in urban areas of China, Biomed. Res. Int., 2016, 2935163
Cited by
Sorted by citations
Neale, P. J., Hylander, S., Banaszak, A. T., Häder, D.-P., Rose, K. C., Vione, D., Wängberg, S.-Å., Jansen, M. A. K., Busquets, R., Andersen, M. P. S., et al. (2025) · Photochemical & Photobiological Sciences · doi:10.1007/s43630-025-00687-x · Cited by 32
“The importance of early life exposure was exemplified by a study of 2260 children born in one of five maternity hospitals in Paris between 2003 and 2006 who underwent examinations at 18 months and/or 8 years of age [263].”
Metadata
- Authors
- Lefebvre, L., Amazouz, H., Rancière, F., & Momas, I.
- Affiliations
- Inserm (FR)
- Corresponding author
- Rancière, Fanny
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2024-06
- Volume
- 930
- Pages
- 172543
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W4394840093
- Cited by
- 7
- References
- 2
- Citations by year
- 2026: 5 · 2025: 2
- FWCI
- 2.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The Science of The Total Environment (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Agence nationale de la recherche (16-CE36-0007-01)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Vitamin D Research Studies
- Keywords
- solar radiation, allergen sensitization, childhood asthma, rhinitis, atopic dermatitis, maternal vitamin D supplementation, prenatal exposure
- MeSH terms
- Child, Environmental Exposure, Female, Humans, Hypersensitivity, Infant, Paris, Pregnancy, Sunlight, Vitamin D, Dietary Supplements
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