The Use of Injectable Collagens for Aesthetic Rejuvenation
Abstract
Bovine collagen was approved by the Food and Drug Administration in 1982 and since that time has remained a primary filler of choice for soft-tissue augmentation of dermal defects. During the past decade, however, perhaps mirroring the growth and overwhelming acceptance of botulinum toxin for wrinkle reduction, there has been an increase in demand and availability of new injectable filler products. A partial list includes the ever-expanding class of hyaluronans (hyaluronic acids), calcium hydroxylapatite, polymethylmethacrylate, poly-L-lactic acid, and silicone oil. There are many more on the immediate horizon that are under investigation both abroad and in the United States. Nevertheless, the collagen family of agents, regardless of their source of derivation, remain a reliable and useful alternative. They have an unparalleled record of safety and efficacy; they have different formulations, which makes them amenable to many indications and user friendly for the physician. And, for patient, the admixture of local anesthesia reduces the discomfort of the injection procedure.
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Collagen- and alginate-based materials have been approved by the FDA for a wide variety of applications, which allows for rapid clinical translation.
“Collagen- and alginate-based materials have been approved by the FDA for a wide variety of applications117, which allows for rapid clinical translation.”
From Towards organoid culture without Matrigel (2021) · cites this paper as [117]
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Towards organoid culture without Matrigel
Kozlowski, M. T., Crook, C. J., & Ku, H. T. (2021) · Communications Biology · doi:10.1038/s42003-021-02910-8 · Cited by 409 · see citing works
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- Authors
- Matarasso, S. L.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Matarasso, Seth L.
- Venue
- Seminars in Cutaneous Medicine and Surgery
- Published
- 2006-09
- Volume
- 25
- Issue
- 3
- Pages
- 151-157
- ISSN
- 1085-5629 (ISSN-L)
- OpenAlex
- W1979620316
- Cited by
- 32
- References
- 13
- Citations by year
- 2025: 1 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 5 · 2012: 2
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Cutaneous Medicine and Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Health Sciences › Medicine › Surgery › Breast Implant and Reconstruction
- Keywords
- injectable collagen, bovine collagen, soft tissue augmentation, dermal fillers, hyaluronic acid, calcium hydroxyapatite, poly(methyl methacrylate), poly(L-lactic acid), silicone oil, wrinkle reduction, local anesthesia
- MeSH terms
- Biocompatible Materials, Collagen, Cosmetic Techniques, Esthetics, Humans, Injections, Subcutaneous, Rejuvenation
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