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Cited by 425

The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.

Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy

Open access
Raj, Sibi, Khurana, Sartaj, Choudhari, Ramesh, Kesari, Kavindra Kumar, Kamal, Mohammad Amjad, Garg, Neha, Ruokolainen, Janne, Das, Bhudev C., Kumar, Dhruv·2021·Seminars in Cancer Biology

Abstract

Nanotechnology has been the latest approach for diagnosis and treatment of cancer, which opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles (NPs) display a broad role in cancer diagnosis and has various advantages over the other conventional chemotherapeutic drug delivery. NPs possess more specific and efficient drug delivery to the targeted tissue, cell, or organs and minimize the risk of side effects. NPs undergo passive and active mode of drug targets to the tumor area with less elimination of the drug from the system. Size and surface characteristics of nanoparticles play a crucial role in modulating nanocarrier efficiency and the biodistribution of chemo drugs in the body. Several types of nanocarriers, such as polymers, dendrimers, liposome-based, and carbon-based, are studied widely in cancer therapy. Although FDA approved very few nanotechnology drugs for cancer therapy, a large number of studies are undergoing for the development of novel nanocarriers for potent cancer therapy. In this review, we discuss details of the nano-based therapeutics and diagnostics strategies, and the potential use of nanomedicines in cancer drug delivery and cancer therapy.

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Crossref · 10.1016/j.semcancer.2019.11.002

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Metadata

Authors
Raj, S., Khurana, S., Choudhari, R., Kesari, K. K., Kamal, M. A., Garg, N., Ruokolainen, J., Das, B. C., & Kumar, D.
Venue
Seminars in Cancer Biology
Publisher
Elsevier BV
Published
2021-02
Volume
69
Pages
166-177
ISSN
1044-579X (ISSN-L)
OpenAlex
W2983922218
Cited by
425
References
138
FWCI
7.96
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy. https://app.cochat.ai/papers/10.1016/j.semcancer.2019.11.002
The paper
Raj, S., Khurana, S., Choudhari, R., Kesari, K. K., Kamal, M. A., Garg, N., Ruokolainen, J., Das, B. C., & Kumar, D. (2021). Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2019.11.002

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