Preterm birth and its impact on renal health
Abstract
Preterm birth occurs in approximately 10% of all births worldwide. Preterm infants have reduced nephron numbers at birth in proportion to gestational age, and are at increased risk of neonatal acute kidney injury as well as higher blood pressure, proteinuria, and chronic kidney disease later in life. Rapid catch-up growth in preterm infants, especially if resulting in obesity, is a risk factor for end-stage kidney disease among children with proteinuric renal disease. Preterm birth, however, is a risk factor not only for the infant because mothers who deliver preterm have an increased risk of having subsequent preterm deliveries as well as hypertension, cardiovascular disease, and renal disease later in life. Preterm birth in a female infant is also a risk factor for her future risk of having a preterm delivery, gestational hypertension, and gestational diabetes, which in turn may impact the development of fetal kidneys and the offspring's risk of hypertension and renal disease. This intergenerational programming cycle, therefore, perpetuates the risks and consequences of prematurity. Interruption of this cycle may be possible through optimization of maternal nutrition and health as well as careful antenatal care, which may in turn reduce the global burden of hypertension and renal disease in subsequent generations.
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Preterm birth is associated with a future risk of poor mental health outcomes.
“PTB is associated with a future risk of poor mental health outcomes.70”
From The transition to parenthood in obstetrics: enhancing prenatal care for 2-generation impact (2022) · cites this paper as [70]
Cites
Epidemiology and causes of preterm birth
Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60074-4 · Cited by 7,801 · see citing works
Vos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., Charlson, F., Davis, A., Degenhardt, L., Dicker, D., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60692-4 · Cited by 6,414 · see citing works
Bhutta, Z. A., Das, J. K., Bahl, R., Lawn, J. E., Salam, R. A., Paul, V. K., Sankar, M. J., Blencowe, H., Rizvi, A., Chou, V. B., et al. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60792-3 · Cited by 1,367 · see citing works
Glomeruli and Blood Pressure: Less of One, More the Other?
Brenner, B. M., Garcia, D. L., & Anderson, S. (1988) · American Journal of Hypertension · doi:10.1093/ajh/1.4.335 · Cited by 1,313 · see citing works
Adair, L. S., Fall, C. H. D., Osmond, C., Stein, A. D., Martorell, R., Ramírez‐Zea, M., Sachdev, H. S., Dahly, D. L., Bas, I., Norris, S. A., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60103-8 · Cited by 894 · see citing works
Lee, A. C., Katz, J., Blencowe, H. K., Cousens, S. N., Kozuki, N., Vogel, J. P., Adair, L. S., Baqui, A. H., Bhutta, Z. A., Caulfield, L. E., et al. (2013) · The Lancet Global Health · doi:10.1016/s2214-109x(13)70006-8 · Cited by 848 · see citing works
Law, C., & Shiell, A. W. (1996) · Journal of Hypertension · doi:10.1097/00004872-199608000-00002 · Cited by 733 · see citing works
The effect of intrauterine growth retardation on the development of renal nephrons
Hinchliffe, S. A., Lynch, M. R. J., Sargent, P. H., Howard, C. V., & van Velzen, D. (1992) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1992.tb13726.x · Cited by 571 · see citing works
Mammen, C., Alabbas, A., Skippen, P. W., Nadel, H. R., Levine, D., Collet, J., & Matsell, D. G. (2011) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2011.10.048 · Cited by 569 · see citing works
Chang, H. H., Larson, J., Blencowe, H. K., Spong, C. Y., Howson, C. P., Cairns‐Smith, S., Lackritz, E., Lee, S. K., Mason, E. M., Serazin, A. C., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61856-x · Cited by 558 · see citing works
Histomorphometric Analysis of Postnatal Glomerulogenesis in Extremely Preterm Infants
Rodriguez, M. M., Gómez, A. H., Abitbol, C. L., Chandar, J. J., Duara, S., & Zilleruelo, G. E. (2004) · Pediatric and Developmental Pathology · doi:10.1007/s10024-003-3029-2 · Cited by 551 · see citing works
Luyckx, V. A., Bertram, J. F., Brenner, B. M., Fall, C. H. D., Hoy, W. E., Ozanne, S. E., & Vikse, B. E. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60311-6 · Cited by 548 · see citing works
Self-citationSelewski, D. T., Charlton, J. R., Jetton, J. G., Guillet, R., Mhanna, M. J., Askenazi, D. J., & Kent, A. L. (2015) · PEDIATRICS · doi:10.1542/peds.2014-3819 · Cited by 548 · see citing works
The fetal and infant origins of disease
Barker, D. J. P. (1995) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1995.tb01730.x · Cited by 530 · see citing works
Abalos, E., Cuesta, C., Carroli, G., Qureshi, Z., Widmer, M., Vogel, J., Souza, J., & on behalf of the WHO Multicountry Survey on Maternal and Newborn Health Research Network (2014) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.12629 · Cited by 528 · see citing works
Systematic Review and Meta-Analysis of Preterm Birth and Later Systolic Blood Pressure
de Jong, F., Monuteaux, M. C., van Elburg, R. M., Gillman, M. W., & Belfort, M. B. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.181784 · Cited by 516 · see citing works
Is Low Birth Weight an Antecedent of CKD in Later Life? A Systematic Review of Observational Studies
White, S. L., Perkovic, V., Cass, A., Chang, C. L., Poulter, N. R., Spector, T. D., Haysom, L., Craig, J. C., Salmi, I. A., Chadban, S. J., et al. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.12.042 · Cited by 492 · see citing works
The intrauterine and early postnatal origins of cardiovascular disease and chronic bronchitis.
Barker, D. J., Osmond, C., & Law, C. (1989) · Journal of Epidemiology & Community Health · doi:10.1136/jech.43.3.237 · Cited by 389 · see citing works
Villar, J., Giuliani, F., Bhutta, Z. A., Bertino, E., Ohuma, E. O., Ismail, L. C., Barros, F. C., Altman, D. G., Victora, C. G., Noble, J. A., et al. (2015) · The Lancet Global Health · doi:10.1016/s2214-109x(15)00163-1 · Cited by 360 · see citing works
The Clinical Importance of Nephron Mass
Luyckx, V. A., & Brenner, B. M. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2009121248 · Cited by 332 · see citing works
Self-citationNephron number, hypertension, renal disease, and renal failure.
Hoy, W., Hughson, M., Bertram, J., Douglas-Denton, R. N., & Amann, K. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005020172 · Cited by 320 · see citing works
Acute Kidney Injury Reduces Survival in Very Low Birth Weight Infants
Koralkar, R., Ambalavanan, N., Levitan, E. B., et al. (2010) · Pediatric Research · doi:10.1203/pdr.0b013e31820b95ca · Cited by 316 · see citing works
Birth weight, malnutrition and kidney-associated outcomes—a global concern
Luyckx, V. A., & Brenner, B. M. (2015) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.251 · Cited by 289 · see citing works
Self-citationTransgenerational developmental programming
Aiken, C., & Ozanne, S. E. (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt043 · Cited by 283 · see citing works
Recognition and Reporting of AKI in Very Low Birth Weight Infants
Carmody, J. B., Swanson, J. R., Rhone, E. T., & Charlton, J. R. (2014) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.05190514 · Cited by 247 · see citing works
Very Low Birth Weight is a Risk Factor for Secondary Focal Segmental Glomerulosclerosis
Hodgin, J. B., Rasoulpour, M., Markowitz, G. S., et al. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.01700408 · Cited by 231 · see citing works
Cardiometabolic Risk Factors in Young Adults Who Were Born Preterm
Sipola‐Leppänen, M., Vääräsmäki, M., Tikanmäki, M., Matinolli, H., Miettola, S., Hovi, P., Wehkalampi, K., Ruokonen, A., Sundvall, J., Pouta, A., et al. (2015) · American Journal of Epidemiology · doi:10.1093/aje/kwu443 · Cited by 226 · see citing works
Birth Characteristics and Subsequent Risks of Maternal Cardiovascular Disease
Bonamy, A. E., Parikh, N. I., Cnattingius, S., Ludvigsson, J. F., & Ingelsson, E. (2011) · Circulation · doi:10.1161/circulationaha.111.034884 · Cited by 223 · see citing works
Long-term follow-up of extremely low birth weight infants with neonatal renal failure
Montan�, B., Chandar, J. J., Duara, S., et al. (2003) · Pediatric Nephrology · doi:10.1007/s00467-003-1186-1 · Cited by 220 · see citing works
Keijzer‐Veen, M. G., Schrevel, M., Finken, M. J. J., et al. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004090783 · Cited by 218 · see citing works
Wlodek, M. E., Mibus, A., Tan, A. L. Y., Siebel, A. L., Owens, J. A., & Moritz, K. M. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007010015 · Cited by 213 · see citing works
Feeding Preterm Infants Today for Later Metabolic and Cardiovascular Outcomes
Lapillonne, A., & Griffin, I. J. (2013) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.11.048 · Cited by 213 · see citing works
Rotteveel, J., van Weissenbruch, M. M., Twisk, J. W. R., & de Waal, H. A. D. (2008) · PEDIATRICS · doi:10.1542/peds.2007-2012 · Cited by 210 · see citing works
The long-term renal and cardiovascular consequences of prematurity
Abitbol, C. L., & Rodriguez, M. M. (2012) · Nature Reviews Nephrology · doi:10.1038/nrneph.2012.38 · Cited by 194 · see citing works
Wlodek, M. E., Westcott, K. T., Siebel, A. L., Owens, J. A., & Moritz, K. M. (2008) · Kidney International · doi:10.1038/ki.2008.153 · Cited by 193 · see citing works
Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies.
Amri, K., Freund, N., Vilar, J., Merlet-Bénichou, C., & Lelièvre-Pégorier, M. (1999) · Diabetes · doi:10.2337/diabetes.48.11.2240 · Cited by 176 · see citing works
Familial Patterns of Preterm Delivery: Maternal and Fetal Contributions
Wilcox, A. J., Skjærven, R., & Lie, R. T. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm319 · Cited by 167 · see citing works
Relation of arterial stiffness with gestational age and birth weight
Cheung, Y. (2004) · Archives of Disease in Childhood · doi:10.1136/adc.2003.025999 · Cited by 167 · see citing works
Nephrotoxic medication exposure in very low birth weight infants
Rhone, E. T., Carmody, J. B., Swanson, J. R., & Charlton, J. R. (2013) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2013.860522 · Cited by 159 · see citing works
Bacchetta, J., Harambat, J., Dubourg, L. D., Guy, B., Liutkus, A., Canterino, I., Kassaï, B., Putet, G., & Cochat, P. (2009) · Kidney International · doi:10.1038/ki.2009.201 · Cited by 136 · see citing works
Catch up growth in low birth weight infants: Striking a healthy balance
Jain, V., & Singhal, A. (2012) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-012-9216-6 · Cited by 130 · see citing works
Salt Sensitivity of Children With Low Birth Weight
Simonetti, G. D., Raio, L., Surbek, D., Nelle, M., Frey, F. J., & Mohaupt, M. G. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.114983 · Cited by 125 · see citing works
Role of the kidney in the prenatal and early postnatal programming of hypertension
Baum, M. G. (2009) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00288.2009 · Cited by 113 · see citing works
Lewandowski, A. J., Davis, E., Yu, G. Z., et al. (2014) · Hypertension · doi:10.1161/hypertensionaha.114.04662 · Cited by 112 · see citing works
Kanguru, L., Bezawada, N., Hussein, J., & Bell, J. S. (2014) · Global Health Action · doi:10.3402/gha.v7.23987 · Cited by 110 · see citing works
Nephrocalcinosis in preterm neonates
Schell-Feith, E. A., Holthe, J. E. K., & van der Heijden, A. J. (2008) · Pediatric Nephrology · doi:10.1007/s00467-008-0908-9 · Cited by 96 · see citing works
Obesity and preterm birth: additive risks in the progression of kidney disease in children
Abitbol, C. L., Chandar, J. J., Rodriguez, M. M., et al. (2009) · Pediatric Nephrology · doi:10.1007/s00467-009-1120-2 · Cited by 95 · see citing works
Keijzer‐Veen, M. G., Kleinveld, H. A., Lequin, M. H., Dekker, F. W., Nauta, J., de Rijke, Y. B., & van der Heijden, B. J. (2007) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2007.06.015 · Cited by 82 · see citing works
Assessment of long-term renal complications in extremely low birth weight children
Kwinta, P., Klimek, M., Drożdż, D., Grudzień, A., Jagła, M., Zasada, M., & Pietrzyk, J. J. (2011) · Pediatric Nephrology · doi:10.1007/s00467-011-1840-y · Cited by 80 · see citing works
Early predictors of hypertension in prematurely born adolescents
Vohr, B. R., Allan, W. C., Katz, K. H., Schneider, K. C., & Ment, L. R. (2010) · Acta Paediatrica · doi:10.1111/j.1651-2227.2010.01926.x · Cited by 79 · see citing works
Effect of birth weight on life-course blood pressure levels among children born premature
Juonala, M., Cheung, M. M. H., Sabin, M. A., Burgner, D. P., Skilton, M. R., Kähönen, M. A. P., Hutri‐Kähönen, N., Lehtimäki, T. J., Jula, A., Laitinen, T. P., et al. (2015) · Journal of Hypertension · doi:10.1097/hjh.0000000000000612 · Cited by 76 · see citing works
Ikezumi, Y., Suzuki, T., Karasawa, T., Yamada, T., Hasegawa, H., Nishimura, H., & Uchiyama, M. (2013) · American Journal of Nephrology · doi:10.1159/000353898 · Cited by 73 · see citing works
Long-Term Effects of Mild Oligonephronia Induced In Utero by Gentamicin in the Rat
Gilbert, T., Lelièvre-Pégorier, M., & Merlet-Bénichou, C. (1991) · Pediatric Research · doi:10.1203/00006450-199111000-00011 · Cited by 72 · see citing works
Pregnancy complications among women born preterm
Boivin, A., Luo, Z., Audibert, F., Mâsse, B. R., Lefebvre, F., Tessier, R., & Nuyt, A. M. (2012) · Canadian Medical Association Journal · doi:10.1503/cmaj.120143 · Cited by 67 · see citing works
Is Nephrocalcinosis in Preterm Neonates Harmful for Long-term Blood Pressure and Renal Function?
Holthe, J. E. K., van Zwieten, P. H. T., Schell-Feith, E. A., et al. (2007) · PEDIATRICS · doi:10.1542/peds.2006-2639 · Cited by 64 · see citing works
Impact of Gestational Age and Birth Weight on Amikacin Clearance on Day 1 of Life
Schreuder, M. F., Wilhelm, A. J., Bökenkamp, A., et al. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.02230409 · Cited by 50 · see citing works
Neonatal nephrocalcinosis: long term follow up
Porter, E., McKie, A., Beattie, T. J., et al. (2006) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/adc.2006.094755 · Cited by 48 · see citing works
Lee, H., Dichtl, S., Mormanová, Z., et al. (2014) · Archives of Disease in Childhood · doi:10.1136/archdischild-2013-304074 · Cited by 40 · see citing works
Rogvi, R. Á., Forman, J. L., Damm, P., & Greisen, G. O. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034001 · Cited by 39 · see citing works
Birth Weight and Creatinine Clearance in Young Adult Twins
Gielen, M., Pinto‐Sietsma, S., Zeegers, M. P., Loos, R. J. F., Fagard, R. H., de Leeuw, P. W., Beunen, G. P., Derom, C. A., & VLIETINCK, R. F. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004030210 · Cited by 38 · see citing works
Risk for Preterm and Very Preterm Delivery in Women Who Were Born Preterm
Boivin, A., Luo, Z., Audibert, F., et al. (2015) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000000813 · Cited by 33 · see citing works
Sandvik, M. K., Iversen, B. M., Irgens, L. M., Skjærven, R., Leivestad, T., Søfteland, E., & Vikse, B. E. (2010) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfq275 · Cited by 32 · see citing works
Long-Term Renal Consequences of Preterm Birth
Sutherland, M. R., Ryan, D., Black, M. J., & Kent, A. L. (2014) · Clinics in Perinatology · doi:10.1016/j.clp.2014.05.006 · Cited by 31 · see citing works
Nishizaki, N., Hirano, D., Nishizaki, Y., et al. (2013) · Clinical and Experimental Nephrology · doi:10.1007/s10157-013-0896-3 · Cited by 31 · see citing works
Consequences of prematurity on adult morbidities
Roggero, P., Giannì, M. L., Garbarino, F., et al. (2013) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2013.01.011 · Cited by 27 · see citing works
Differences in Risk Factors for Recurrent Versus Incident Preterm Delivery
Grantz, K. L., Hinkle, S. N., Mendola, P., Sjaarda, L. A., Leishear, K., & Albert, P. S. (2015) · American Journal of Epidemiology · doi:10.1093/aje/kwv032 · Cited by 27 · see citing works
Kent, A. L., Douglas-Denton, R. N., Shadbolt, B., et al. (2009) · Pediatric Nephrology · doi:10.1007/s00467-008-1114-5 · Cited by 26 · see citing works
Early life obesity and chronic kidney disease in later life
Yim, H. E., & Yoo, K. H. (2014) · Pediatric Nephrology · doi:10.1007/s00467-014-2922-4 · Cited by 24 · see citing works
Steen, E., Bonamy, A. E., Norman, M., & Hellström-Westas, L. K. (2015) · Acta Paediatrica · doi:10.1111/apa.13095 · Cited by 19 · see citing works
Hibino, S., Abe, Y., Watanabe, S., et al. (2015) · Pediatric Nephrology · doi:10.1007/s00467-015-3149-8 · Cited by 18 · see citing works
Proteinuria and glomerular hypertrophy in extremely low‐birthweight children
Hayashi, A., Santo, Y., & Satomura, K. (2014) · Pediatrics International · doi:10.1111/ped.12466 · Cited by 18 · see citing works
Nephrocalcinosis in pre-term neonates: A study of incidence and risk factors
Mohamed, G., Ibrahiem, M., & Hameed, W. A. (2014) · Saudi Journal of Kidney Diseases and Transplantation · doi:10.4103/1319-2442.128524 · Cited by 18 · see citing works
Increased Albuminuria in 4-Year-Old Preterm-Born Children with Normal Height
Vieux, R., Hascoët, J., Franck, P., et al. (2012) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2011.12.005 · Cited by 12 · see citing works
Prematurity and programming: contribution of neonatal Intensive Care Unit interventions
Kalhan, S. C., & Wilson-Costello, D. E. (2012) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s204017441200061x · Cited by 11 · see citing works
Kidney Stones: A Fetal Origins Hypothesis
Howles, S., Edwards, M. H., Cooper, C. C., & Thakker, R. V. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1993 · Cited by 10 · see citing works
Secondary Focal Segmental Glomerulosclerosis in an Adolescent Born with a Very Low Birth Weight
Fuke, Y., Murata, Y., Hemmi, S., et al. (2014) · Internal Medicine · doi:10.2169/internalmedicine.53.2552 · Cited by 5 · see citing works
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The transition to parenthood in obstetrics: enhancing prenatal care for 2-generation impact
Monk, C., Dimidjian, S., Galinsky, E., Gregory, K. D., Hoffman, M. C., Howell, E. A., Miller, E. S., Osborne, C., Rogers, C. E., Saxbe, D. E., et al. (2022) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2022.100678 · Cited by 19 · see citing works
- Authors
- Luyckx, V. A.
- Venue
- Seminars in Nephrology
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 37
- Issue
- 4
- Pages
- 311-319
- ISSN
- 0270-9295 (ISSN-L)
- OpenAlex
- W2735944743
- Cited by
- 85
- References
- 77
- Citations by year
- 2026: 9 · 2025: 4 · 2024: 6 · 2023: 7 · 2022: 14 · 2021: 16 · 2020: 8 · 2019: 9 · 2018: 12
- FWCI
- 1.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Nephrology (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Keywords
- preterm birth, kidney health, nephron number, neonatal acute kidney injury, chronic kidney disease, proteinuria, hypertension, catch-up growth, childhood obesity, end-stage renal disease, intergenerational programs, maternal hypertension, gestational diabetes mellitus, maternal nutrition, prenatal care, fetal kidney development
- MeSH terms
- Adolescent, Blood Pressure, Calcinosis, Child, Child, Preschool, Gestational Age, Glomerular Filtration Rate, Humans, Hypertension, Kidney Diseases, Nephrons, Risk Factors, Premature Birth, Young Adult, Acute Kidney Injury
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