The Primary Obesity Surgery Endolumenal (POSE) procedure: one-year patient weight loss and safety outcomes
Abstract
Background Obesity is at epidemic proportions and increasing. Bariatric surgical procedures have demonstrated better durable weight loss than diet and exercise; however, risk may limit adoption of these procedures. Endoscopic procedures may offer less risk, lower cost, and satisfactory results, but limited safety and outcome data is available. The present report describes the Primary Obesity Surgery Endolumenal (POSE(™)) procedure, perioperative care, and 1-year safety and weight loss outcomes for a single center.Methods One hundred forty-seven patients undergoing the POSE procedure between July 2011 and January 2013 were followed for 1 year. Overall patient status and weight data were collected at baseline and at 3, 6, and 12 months. Outcomes included change in total weight loss (TWL), percentage of TWL (%TWL), percentage of excess weight loss (%EWL), and adverse events.Results Patients tolerated the procedure well with no serious short-term or long-term adverse events. All but 1 patient were discharged within 24 hours of the procedure. Baseline body mass index (BMI) was 38.0 ± 4.8 kg/m(2). Initial weight (106.8 ± 18.2 kg) was significantly reduced at 3, 6, and 12 months. At 1 year, 116 patients (79% of total) who were available for follow-up had a mean TWL of 16.6 ± 9.7 kg, %TWL of 15.1 ± 7.8, and %EWL of 44.9 ± 24.4.Conclusion After 1-year follow-up, POSE was considered an effective, safe and well tolerated procedure for the treatment of patients with obesity.
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Two RCTs and 1 cohort study investigating the Pose® procedure reported excess weight loss between 16% and 45%.
“Two RCTs and 1 cohort study investigated the effect of the Pose® procedure and reported EWL between 16–45% [149–151].”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [151]
The safety profile of the Pose® procedure seems acceptable, but certainty in the evidence was very low.
“The procedure safety profile seems acceptable, however certainty in the evidence was very low.”
From Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP (2020) · cites this paper as [151]
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- Authors
- López-Nava, G., Bautista-Castaño, I., Jimenez, A., de Grado, T., & Fernandez-Corbelle, J. P.
- Affiliations
- Hospital Universitario HM Sanchinarro (ES)
- Corresponding author
- López-Nava, Gontrand
- Venue
- Surgery for Obesity and Related Diseases
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 11
- Issue
- 4
- Pages
- 861-865
- ISSN
- 1550-7289 (ISSN-L)
- OpenAlex
- W2086295929
- Cited by
- 144
- References
- 15
- Citations by year
- 2025: 6 · 2024: 15 · 2023: 8 · 2022: 5 · 2021: 17 · 2020: 18 · 2019: 19 · 2018: 14 · 2017: 19 · 2016: 21 · 2015: 2
- FWCI
- 13.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Surgery for Obesity and Related Diseases (publishedVersion)
- PubMed (publishedVersion)
- Acceda (Universidad de Las Palmas de Gran Canaria) (submittedVersion)
- Funders
- American Society for Gastrointestinal Endoscopy
- U.S. Food and Drug Administration
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- MeSH terms
- Adult, Aged, Female, Follow-Up Studies, Gastroscopy, Humans, Male, Middle Aged, Obesity, Morbid, Retrospective Studies, Time Factors, Gastroplasty, Weight Loss, Body Mass Index, Treatment Outcome, Young Adult
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