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Evidence-Based Guidelines for Preventing and Managing Side Effects of Multiple Myeloma
Abstract
Objective To review disease-related symptoms and side effects of treatment in patients with multiple myeloma (MM). Data sources Peer-reviewed articles, research studies, and clinical guidelines. Conclusion New therapies provide patients with extended survival, but in many cases this benefit is counterbalanced by an increased incidence of side effects. Preservation of organ function, while managing side effects, is essential for the care of patients with MM. Implications for nursing practice Disease- and treatment-related adverse events are prevalent in patients with MM. Patient, family, and health care professional education is essential to monitor and manage these side effects.
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“Non-targeted drugs, while effective, can also harm normal healthy cells, leading to adverse effects such as gastrointestinal problems (nausea, vomiting, diarrhea, and constipation) [57], myelosuppression (reduction in white blood cells and platelets), alopecia, anemia, liver and kidney impairment, and an increased risk of infections [58, 59].”
From Multiple myeloma: signaling pathways and targeted therapy (2024) · cites this paper as [59]
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Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma
Lonial, S., Dimopoulos, M., Palumbo, A., White, D., Grosicki, S., Spicka, I., Walter-Croneck, A., Moreau, P., Mateos, M.-V., Magen, H., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1505654 · Cited by 1,322
Richardson, P. G., Siegel, D. S., Vij, R., Hofmeister, C. C., Baz, R., Jagannath, S., Chen, C., Lonial, S., Jakubowiak, A., Bahlis, N., et al. (2014) · Blood · doi:10.1182/blood-2013-11-538835 · Cited by 381
In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2
Maes, K., Nemeth, E., Roodman, G. D., Huston, A., Esteve, F., Freytes, C., Callander, N., Katodritou, E., Tussing-Humphreys, L., Rivera, S., et al. (2010) · Blood · doi:10.1182/blood-2010-03-274571 · Cited by 132
Research works printed but not linked: 82
- Steinbach, 2017, Strategies for selecting the optimal treatment in newly-diagnosed multiple myeloma patients, Semin Oncol Nurs, 33, 10.1016/j.soncn.2017.05.003 · DOI
- Noonan, 2017, Immunomodulatory drugs and protease inhibitors in the treatment of multiple myeloma, Semin Oncol Nurs, 33, 10.1016/j.soncn.2017.05.005 · DOI
- Catamero, 2017, Immunotherapy in multiple myeloma, Semin Oncol Nurs, 33
- Terpos, 2014, Management of bone disease in multiple myeloma, Expert Rev Hematol, 7, 113, 10.1586/17474086.2013.874943 · DOI
- Roodman, 2004, Mechanisms of bone metastasis, N Engl J Med, 350, 1655, 10.1056/NEJMra030831 · DOI
- Rajkumar, 2014, International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma, Lancet Oncol, 15, e538, 10.1016/S1470-2045(14)70442-5 · DOI · Paper page
- Dimopoulos, 2015, Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement, J Clin Oncol, 33, 657, 10.1200/JCO.2014.57.9961 · DOI
- Brigle, 2017, Pathobiology and diagnosis of multiple myeloma, Semin Oncol Nurs, 10.1016/j.soncn.2017.05.012 · DOI
- Terpos, 2003, Autologous stem cell transplantation in multiple myeloma: improved survival in nonsecretory multiple myeloma but lack of influence of age, status at transplant, previous treatment and conditioning regimen. A single center experience in 127 patients, Bone Marrow Transplant, 31, 163, 10.1038/sj.bmt.1703818 · DOI
- Terpos, 2013, International Myeloma Working Group recommendations for the treatment of multiple myeloma–related bone disease, J Clin Oncol, 31, 2347, 10.1200/JCO.2012.47.7901 · DOI
- Terpos, 2015, European Myeloma Network guidelines for the management of multiple myeloma-related complications, Haematologica, 100, 1254, 10.3324/haematol.2014.117176 · DOI
- Rosen, 2003, Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double blind, multicenter, comparative trial, Cancer, 98, 1735, 10.1002/cncr.11701 · DOI
- Morgan, 2011, Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial, Lancet Oncol, 12, 743, 10.1016/S1470-2045(11)70157-7 · DOI
- Von Moos, 2010, Effects of denosumab versus zoledronic acid (ZA) on pain in patients (pts) with advanced cancer (excluding breast and prostate) or multiple myeloma (MM): results from a randomized phase III clinical trial, ASCO Meet Abstr, 28, 9043
- Raje, 2013, Evaluating results from the multiple myeloma subset of patients treated with denosumab or zoledronic acid (ZA) in a randomized phase III study, ASCO Meet Abstr, 31, 8589
- Rome, 2011, Mobility and safety in the multiple myeloma survivor: survivorship care plan of the International Myeloma Foundation Nurse Leadership Board, Clin J Oncol Nurs, 15, 41, 10.1188/11.S1.CJON.41-52 · DOI
- Miceli, 2011, Maintaining bone health in patients with multiple myeloma, Clin J Oncol Nurs, 15, 9, 10.1188/11.S1.CJON.9-23 · DOI
- Coleman, 2003, Facilitating exercise adherence for patients with multiple myeloma, Clin J Oncol Nurs, 7, 529, 10.1188/03.CJON.529-534 · DOI
- Finkel, 2016, Paraprotein-related kidney disease: evaluation and treatment of myeloma cast nephropathy, Clin J Am Soc Nephrol, 11, 2256, 10.2215/CJN.01640216 · DOI
- Dimopoulos, 2008, Pathogenesis and treatment of renal failure in multiple myeloma, Leukemia, 22, 1485, 10.1038/leu.2008.131 · DOI
- Dimopoulos, 2016, International Myeloma Working Group Recommendations for the diagnosis and management of myeloma-related renal impairment, J Clin Oncol, 34, 1544, 10.1200/JCO.2015.65.0044 · DOI
- Faiman, 2011, Renal complications in multiple myeloma and related disorders: survivorship care plan of the International Myeloma Foundation Nurse Leadership Board, Clin J Oncol Nurs, 15, 66, 10.1188/11.CJON.S1.66-76 · DOI
- Inker, 2014, KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD, Am J Kidney Dis, 63, 713, 10.1053/j.ajkd.2014.01.416 · DOI
- Kurtin, 2012, Myeloid toxicity of cancer treatment, J Adv Pract Oncol, 3, 209
- Valkovic, 2015, Infections in hospitalised patients with multiple myeloma: main characteristics and risk factors, Turk J Haematol, 32, 234, 10.4274/tjh.2013.0173 · DOI
- Huang, 2017, Risk factors and characteristics of blood stream infections in patients with newly diagnosed multiple myeloma, BMC Infect Dis, 17, 33, 10.1186/s12879-016-2155-1 · DOI
- Crea, 2009, Pharmacologic rationale for early G-CSF prophylaxis in cancer patients and role of pharmacogenetics in treatment optimization, Crit Rev Oncol Hematol, 72, 21, 10.1016/j.critrevonc.2008.10.014 · DOI
- Miceli, 2008, Myelosuppression associated with novel therapies in patients with multiple myeloma: consensus statement of the IMF Nurse Leadership Board, Clin J Oncol Nurs, 12, 13, 10.1188/08.CJON.S1.13-19 · DOI
- Moreau, 2016, Oral ixazomib, lenalidomide, and dexamethasone for multiple myeloma, N Engl J Med, 374, 1621, 10.1056/NEJMoa1516282 · DOI · Paper page
- Palumbo, 2012, How to manage neutropenia in multiple myeloma, Clin Lymphoma Myeloma Leuk, 12, 5, 10.1016/j.clml.2011.11.001 · DOI
- Gay, 2010, Management of disease- and treatment-related complications in patients with multiple myeloma, Med Oncol, 27, S43, 10.1007/s12032-010-9542-z · DOI
- Palumbo, 2014, International Myeloma Working Group Consensus Statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation, J Clin Oncol, 32, 587, 10.1200/JCO.2013.48.7934 · DOI
- Faller, 2016, Immune thrombocytopenia purpura associated with multiple myeloma, Ann Hematol, 95, 1371, 10.1007/s00277-016-2694-y · DOI
- Gonsalves, 2016, Limiting early mortality: do's and don'ts in the management of patients with newly diagnosed multiple myeloma, Am J Hematol, 91, 101, 10.1002/ajh.24129 · DOI
- Smith, 2015, Recommendations for the use of WBC growth factors: American Society of Clinical Oncology Clinical Practice Guideline Update, J Clin Oncol, 33, 3199, 10.1200/JCO.2015.62.3488 · DOI
- Rizzo, 2010, American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer, Blood, 116, 4045, 10.1182/blood-2010-08-300541 · DOI
- Slichter, 2010, Dose of prophylactic platelet transfusions and prevention of hemorrhage, N Engl J Med, 362, 600, 10.1056/NEJMoa0904084 · DOI
- Leebeek, 2016, Update of thrombosis in multiple myeloma, Thromb Res, 140, S76, 10.1016/S0049-3848(16)30103-7 · DOI
- Baz, 2005, The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma, Mayo Clin Proc, 80, 1568, 10.4065/80.12.1568 · DOI
- Palumbo, 2008, Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma, Leukemia, 22, 414, 10.1038/sj.leu.2405062 · DOI
- Rome, 2008, Thromboembolic events associated with novel therapies in patients with multiple myeloma: consensus statement of the IMF Nurse Leadership Board, Clin J Oncol Nurs, 12, 21, 10.1188/08.CJON.S1.21-27 · DOI
- Elice, 2006, Acquired resistance to activated protein C (aAPCR) in multiple myeloma is a transitory abnormality associated with an increased risk of venous thromboembolism, Br J Haematol, 134, 399, 10.1111/j.1365-2141.2006.06208.x · DOI
- Niesvizky, 2010, Complications of multiple myeloma therapy, part 2: risk reduction and management of venous thromboembolism, osteonecrosis of the jaw, renal complications, and anemia, J Natl Compr Canc Netw, 8, S13, 10.6004/jnccn.2010.0112 · DOI
- Li, 2016, Cardiovascular complications of novel multiple myeloma treatments, Circulation, 133, 908, 10.1161/CIRCULATIONAHA.115.018351 · DOI
- Auwerda, 2007, Prothrombotic coagulation abnormalities in patients with newly diagnosed multiple myeloma, Haematologica, 92, 279, 10.3324/haematol.10454 · DOI
- Van Marion, 2008, Prospective evaluation of coagulopathy in multiple myeloma patients before, during and after various chemotherapeutic regimens, Leuk Res, 32, 1078, 10.1016/j.leukres.2007.12.002 · DOI
- Minnema, 2003, Extremely high levels of von Willebrand factor antigen and of procoagulant factor VIII found in multiple myeloma patients are associated with activity status but not with thalidomide treatment, J Thromb Haemost, 1, 445, 10.1046/j.1538-7836.2003.00083.x · DOI
- Rickles, 2003, TIssue factor, thrombin, and cancer, Chest, 124, 58S, 10.1378/chest.124.3_suppl.58S · DOI
- Auwerda, 2011, Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma, Thromb Haemost, 105, 14, 10.1160/TH10-03-0187 · DOI
- Srkalovic, 2004, Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic disease, Cancer, 101, 558, 10.1002/cncr.20405 · DOI
- Baz, 2014, Pomalidomide, cyclophosphamide, and dexamethasone is superior to pomalidomide and dexamethasone in relapsed and refractory myeloma: results of a multicenter randomized phase II study, Blood, 124, 303, 10.1182/blood.V124.21.303.303 · DOI
- Rajkumar, 2010, Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial, Lancet Oncol, 11, 29, 10.1016/S1470-2045(09)70284-0 · DOI · Paper page
- Anaissie, 2012, Prophylactic recombinant erythropoietin therapy and thalidomide are predictors of venous thromboembolism in patients with multiple myeloma: limited effectiveness of thromboprophylaxis, Cancer, 118, 549, 10.1002/cncr.26302 · DOI
- Lee, 2010, Thrombosis in cancer: an update on prevention, treatment, and survival benefits of anticoagulants, Hematology Am Soc Hematol Educ Program, 2010, 144, 10.1182/asheducation-2010.1.144 · DOI
- Lyman, 2015, Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update 2014, J Clin Oncol, 33, 654, 10.1200/JCO.2014.59.7351 · DOI
- Kristinsson, 2010, Thrombosis in multiple myeloma, Hematology Am Soc Hematol Educ Program, 2010, 437, 10.1182/asheducation-2010.1.437 · DOI
- Bagratuni, 2013, Clinical and genetic factors associated with venous thromboembolism in myeloma patients treated with lenalidomide-based regimens, Am J Hematol, 88, 765, 10.1002/ajh.23504 · DOI
- Zangari, 2011, Low venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: review of data from phase 3 trials and studies of novel combination regimens, Clin Lymphoma Myeloma Leuk, 11, 228, 10.1016/j.clml.2011.03.006 · DOI
- Lee, 2015, Clinical outcomes of venous thromboembolism with dalteparin therapy in multiple myeloma patients, Thromb Res, 136, 974, 10.1016/j.thromres.2015.09.021 · DOI
- Richardson, 2012, Management of treatment-emergent peripheral neuropathy in multiple myeloma, Leukemia, 26, 595, 10.1038/leu.2011.346 · DOI
- Broyl, 2012, General aspects and mechanisms of peripheral neuropathy associated with bortezomib in patients with newly diagnosed multiple myeloma, Semin Hematol, 49, 249, 10.1053/j.seminhematol.2012.04.001 · DOI
- Mohty, 2010, Peripheral neuropathy and new treatments for multiple myeloma: background and practical recommendations, Haematologica, 95, 311, 10.3324/haematol.2009.012674 · DOI
- Tariman, 2008, Peripheral neuropathy associated with novel therapies in patients with multiple myeloma: consensus statement of the IMF Nurse Leadership Board, Clin J Oncol Nurs, 12, 29, 10.1188/08.CJON.S1.29-35 · DOI
- Stephens, 2014, The work of living with a rare cancer: multiple myeloma, J Adv Nurs, 70, 2800, 10.1111/jan.12430 · DOI
- Poncelet, 1998, An algorithm for the evaluation of peripheral neuropathy, Am Fam Physician, 755
- Klimberg, 2005, Is glutamine effective in enhancing host immune response to tumors?, J Nutr, 135, 2920S, 10.1093/jn/135.12.2920S · DOI
- Hansen, 2006, Glutamine supplementation to reduce oral mucositis in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation: a feasibility study, Biol Blood Marrow Transplant, 12, 144, 10.1016/j.bbmt.2005.11.441 · DOI
- Wang, 2007, Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients, Oncologist, 12, 312, 10.1634/theoncologist.12-3-312 · DOI
- Amara, 2008, Oral glutamine for the prevention of chemotherapy-induced peripheral neuropathy, Ann Pharmacother, 42, 1481, 10.1345/aph.1L179 · DOI
- Smith, 2013, Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial, JAMA, 309, 1359, 10.1001/jama.2013.2813 · DOI
- Majithia, 2016, New practical approaches to chemotherapy-induced neuropathic pain: prevention, assessment, and treatment, Oncology, 30
- Dobson, 2014, Benefits of exercise intervention in reducing neuropathic pain, Front Cell Neurosci, 8, 102, 10.3389/fncel.2014.00102 · DOI
- Hershman, 2014, Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology Clinical Practice Guideline, J Clin Oncol, 32, 1941, 10.1200/JCO.2013.54.0914 · DOI
- Faiman, 2016, Diarrhea in multiple myeloma: a review of the literature, Clin J Oncol Nurs, 20, E100, 10.1188/16.CJON.E100-E105 · DOI
- Ritts, 2016, Cardiac consideration for modern multiple myeloma therapies, Am Coll Cardiol
- Shakir, 2009, Chemotherapy induced cardiomyopathy: pathogenesis monitoring and management, J Clin Med Res, 1, 8
- Ewer, 2015, Cardiotoxicity of anticancer treatments: what the cardiologist needs to know, Nat Rev Cardiol, 7, 564, 10.1038/nrcardio.2010.121 · DOI
- Bovelli, 2010, Cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease: ESMO Clinical Practice Guidelines, Ann Oncol, 21, v277, 10.1093/annonc/mdq200 · DOI
- Florescu, 2015, Chemotherapy-induced cardiotoxicity, J Clin Med, 8, 59
- Brana, 2010, Cardiotoxicity, Ann Oncol, 21, vii173, 10.1093/annonc/mdq295 · DOI
- Ritts, 2017, Current concepts of cardiac amyloidosis: diagnosis, clinical management, and the need for collaboration, Heart Fail Clin, 13, 409, 10.1016/j.hfc.2016.12.003 · DOI
- Okwusoa, 2015, Burgeoning cardio-oncology programs, challenges and opportunities for early career cardiologists/faculty directors, J Am Coll Cardiol, 66, 1193, 10.1016/j.jacc.2015.07.033 · DOI
Cited by
Sorted by citations
Multiple myeloma: signaling pathways and targeted therapy
Lu, Q., Yang, D., Li, H., Niu, T., & Tong, A. (2024) · Molecular biomedicine · doi:10.1186/s43556-024-00188-w · Cited by 90
Metadata
- Authors
- Bertolotti, P., Pierre, A., Rome, S., & Faiman, B.
- Corresponding author
- Bertolotti, Page
- Venue
- Seminars in Oncology Nursing
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 33
- Issue
- 3
- Pages
- 332-347
- ISSN
- 0749-2081 (ISSN-L)
- OpenAlex
- W2739288118
- Cited by
- 9
- References
- 3
- Citations by year
- 2025: 2 · 2024: 2 · 2022: 3 · 2021: 1 · 2017: 1
- FWCI
- 0.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Oncology Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Multiple Myeloma Research and Treatments
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Bone health and treatments
- Keywords
- multiple myeloma, treatment side effects, adverse events, symptom management, organ function preservation, nursing care, patient education, family education, health professions education, evidence-based recommendations
- MeSH terms
- Antineoplastic Agents, Humans, Multiple Myeloma, Survival Analysis, Practice Guidelines as Topic, Evidence-Based Medicine
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