The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
Open accessAbstract
SUMMARY Mechanisms governing muscle satellite cell withdrawal from cell cycle to enter into quiescence remain poorly understood. We studied the role of angiopoietin 1 (Ang1) and its receptor Tie-2 in the regulation of myogenic precursor cell (mpc) fate. In human and mouse, Tie-2 was preferentially expressed by quiescent satellite cells in vivo and reserve cells (RCs) in vitro. Ang1/Tie-2 signaling, through ERK1/2 pathway, decreased mpc proliferation and differentiation, increased the number of cells in G0, increased expression of RC-associated markers (p130, Pax7, Myf-5, M-cadherin), and downregulated expression of differentiation-associated markers. Silencing Tie-2 had opposite effects. Cells located in the satellite cell neighborhood (smooth muscle cells, fibroblasts) up-regulated RC-associated markers by secreting Ang1 in vitro. In vivo, Tie-2 blockade and Ang1 overexpression increased the number of cycling and quiescent satellite cells, respectively. We propose that Ang1/ Tie-2 signaling regulates mpc self-renewal by controlling the return to quiescence of a subset of satellite cells.
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Cites
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Self-citationAsymmetric self-renewal and commitment of satellite stem cells in muscle
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Direct Isolation of Satellite Cells for Skeletal Muscle Regeneration
Montarras, D., Morgan, J., Collins, C., Relaix, F., Zaffran, S., Cumano, A., Partridge, T., & Buckingham, M. (2005) · Science · doi:10.1126/science.1114758 · Cited by 1,100 · cited 6×
“, 2005) or fresh isolated quiescent satellite cells (Montarras et al., 2005).”
InfluentialSelf-citationBrack, A. S., Conboy, I. M., Conboy, M. J., Shen, J., & Rando, T. A. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.10.006 · Cited by 682
Angiopoietins: a link between angiogenesis and inflammation
Fiedler, U., & Augustin, H. G. (2006) · Trends in Immunology · doi:10.1016/j.it.2006.10.004 · Cited by 606
Molecular Signature of Quiescent Satellite Cells in Adult Skeletal Muscle
Fukada, S.-I., Uezumi, A., Ikemoto, M., Masuda, S., Segawa, M., Tanimura, N., Yamamoto, H., Miyagoe-Suzuki, Y., & Takeda, S. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0019 · Cited by 506
Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
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Satellite Cells and the Muscle Stem Cell Niche
Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166
Self-citationSubstrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
Gilbert, P. M., Havenstrite, K. L., Magnusson, K. E. G., Sacco, A., Leonardi, N. A., Kraft, P., Nguyen, N. K., Thrun, S., Lutolf, M. P., & Blau, H. M. (2010) · Science · doi:10.1126/science.1191035 · Cited by 1,587
Building Muscle: Molecular Regulation of Myogenesis
Bentzinger, C. F., Wang, Y. X., & Rudnicki, M. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008342 · Cited by 1,195
Self-citationSatellite Cells and Skeletal Muscle Regeneration
Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719
Self-citationTherapeutic targeting of the angiopoietin–TIE pathway
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Metadata
- Authors
- Abou-Khalil, R., Le Grand, F., Pallafacchina, G., Valable, S., Authier, F.-J., Rudnicki, M. A., Gherardi, R. K., Germain, S., Chretien, F., Sotiropoulos, A., Lafuste, P., Montarras, D., & Chazaud, B.
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 5
- Issue
- 3
- Pages
- 298-309
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W2066123991
- Cited by
- 235
- References
- 8
- FWCI
- 6.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Abou-Khalil, R., Le Grand, F., Pallafacchina, G., Valable, S., Authier, F.-J., Rudnicki, M. A., Gherardi, R. K., Germain, S., Chretien, F., Sotiropoulos, A., Lafuste, P., Montarras, D., & Chazaud, B. (2009). Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal. Cell Stem Cell. https://doi.org/10.1016/j.stem.2009.06.001
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