GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice
Li, Gang, Bien-Ly, Nga, Andrews-Zwilling, Yaisa, Xu, Qin, Bernardo, Aubrey, Ring, Karen, Halabisky, Brian, Deng, Changhui, Mahley, Robert W., Huang, Yadong·2009·Cell Stem Cell
Cited by (288)
Items 101–200 of 288
- Benzodiazepines in Alzheimer’s disease: beneficial or detrimental effectsHayder Mutter Al-Kuraishy, Ali Ismail Al-Gareeb, Hebatallah M. Saad, Gaber El‐Saber Batiha · 2022 · Inflammopharmacology
- Treating Brain Disorders by Targeting Adult Neural Stem CellsHechen Bao, Juan Song · 2018 · Trends in Molecular Medicine
- Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in miceAnna K. Engstrom, Jessica M. Snyder, Nobuyo Maeda, Zhengui Xia · 2017 · Molecular Neurodegeneration
- D-serine increases adult hippocampal neurogenesisSébastien Sultan, Elias Gebara, Kristell Moullec, Nicolas Toni · 2013 · Frontiers in Neuroscience
- Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse modelsYadong Huang · 2011 · Biochemical Society Transactions
- APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 yearsJoy L. Taylor, Blake K. Scanlon, Michelle E. Farrell, Beatriz Hernandez, Maheen M. Adamson, John Wesson Ashford, Art M. Noda, Greer M. Murphy, Michael Walter Weiner · 2014 · Neurobiology of Aging
- Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive PathwaysCarsten Schulte, Maddalena Ripamonti, Elisa Maffioli, Martino Alfredo Cappelluti, Simona Nonnis, Luca Puricelli, Jacopo Lamanna, Claudio Piazzoni, Alessandro Podestà, Cristina Lenardi et al. · 2016 · Frontiers in Cellular Neuroscience
- Identification of key genes and pathways for Alzheimer’s disease via combined analysis of genome-wide expression profiling in the hippocampusMeng Wu, Ke-Chi Fang, Weixiao Wang, Wei Lin, Liyuan Guo, Jing Wang · 2019 · Biophysics Reports
- Postnatal Lipopolysaccharide Exposure Impairs Adult Neurogenesis and Causes Depression-like Behaviors Through Astrocytes Activation Triggering GABAA Receptor DownregulationMin Liang, Haiquan Zhong, Jing Rong, Yingchun Li, Chunting Zhu, Li Zhou, Rong Zhou · 2019 · Neuroscience
- A multi‐hit hypothesis for an APOE4 ‐dependent pathophysiological stateSteele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine et al. · 2022 · European Journal of Neuroscience
- Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement miceHunter, Jesse M., Cirrito, John R., Restivo, Jessica L., Kinley, Robert D., Sullivan, Patrick M., Holtzman, David M., Koger, Deanna, Delong, Cynthia, Lin, Suizhen, Zhao, Lingzhi et al. · 2012 · Brain Research
- Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 MiceTong, Leslie M., Yoon, Seo Yeon, Andrews-Zwilling, Yaisa, Yang, Alyssa, Lin, Victoria, Lei, Hanci, Huang, Yadong · 2016 · The Journal of Neuroscience
- Theta and gamma oscillatory dynamics in mouse models of Alzheimer’s disease: A path to prospective therapeutic interventionSonam Fathima Mehak, Apoorva Bettagere Shivakumar, Sparsha Kumari, Bhadra Muralidharan, Gireesh Gangadharan · 2022 · Neuroscience & Biobehavioral Reviews
- Cognitive Deficits and Disruption of Neurogenesis in a Mouse Model of Apolipoprotein E4 Domain InteractionSamuel Olusegun Adeosun, Xu Hou, Baoying Zheng, Craig A. Stockmeier, Xiao‐Ming Ou, Ian A. Paul, Thomas H. Mosley, Karl Heinrich Weisgraber, Jun Ming Wang · 2013 · Journal of Biological Chemistry
- Insights on benzodiazepines' potential in Alzheimer's diseaseHayder Mutter Al-Kuraishy, Ali Ismail Al-Gareeb, Abdulrahman Ahmed Alsayegh, Wafaa F. Abusudah, Najlaa H. Almohmadi, Omayma A. Eldahshan, Eman Ahmed, Gaber El‐Saber Batiha · 2023 · Life Sciences
- Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's DiseaseEce Kocagöncü, David Nesbitt, Tina Emery, Laura E. Hughes, Richard N. Henson, Cam-CAN, James Benedict Rowe · 2022 · Journal of Neuroscience
- β‐catenin signaling modulates the tempo of dendritic growth of adult‐born hippocampal neuronsJana Heppt, Marie‐Theres Wittmann, Iris Schäffner, Charlotte Billmann, Jingzhong Zhang, Daniela M. Vogt Weisenhorn, Nilima Prakash, Wolfgang Wurst, Makoto Mark Taketo, Dieter Chichung Lie · 2020 · The EMBO Journal
- Neural stem cells and adult brain fatty acid metabolism: Lessons from the 3xTg model of Alzheimer's diseaseLaura K. Hamilton, Karl J. L. Fernandes · 2017 · Biology of the Cell
- Learning from inhibition: Functional roles of hippocampal CA1 inhibition in spatial learning and memoryNuri Jeong, Annabelle C. Singer · 2022 · Current Opinion in Neurobiology
- Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR miceLin, Lan-yan, Zhang, Jing, Dai, Xiao-man, Xiao, Nai-an, Wu, Xi-lin, Wei, Zhen, Fang, Wen-ting, Zhu, Yuan-gui, Chen, Xiao-chun · 2016 · Molecular Neurodegeneration
- APOEgene and neuropsychiatric disorders and endophenotypes: A comprehensive reviewDiego A. Forero, Sandra López‐León, Yeimy González‐Giraldo, Daniel Robert Dries, Angela J. Pereira‐Morales, Karen M. Jiménez, Juan E. Franco‐Restrepo · 2016 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 alleleHiramani Dhungana, Taisia Rõlova, Ekaterina Savchenko, Sara Wojciechowski, Kaisa Savolainen, Anna‐Kaisa Ruotsalainen, Patrick M. Sullivan, Jari Koıstınaho, Tarja Malm · 2013 · Journal of Neuroinflammation
- The role of neurogenesis during development and in the adult brainXing Jin · 2016 · European Journal of Neuroscience
- Tetrahydrohyperforin Increases Adult Hippocampal Neurogenesis in Wild-Type and APPswe/PS1ΔE9 MiceAna C. Abbott, Carla Calderon Toledo, Florencia C. Aránguiz, Nibaldo C. Inestrosa, Lorena Varela‐Nallar · 2013 · Journal of Alzheimer s Disease
- Identification of ApoE as an autocrine/paracrine factor that stimulates neural stem cell survival via MAPK/ERK signaling pathwayHui Theng Gan, Muly Tham, Srivats Hariharan, Srinivas Ramasamy, Yuan Hong Yu, Sohail Ahmed · 2011 · Journal of Neurochemistry
- New genetic players in late-onset Alzheimer's diseaseAnamika Misra, Sankha Shubhra Chakrabarti, Indrajeet Singh Gambhir · 2018 · The Indian Journal of Medical Research
- Neurogenesis and developmental anesthetic neurotoxicityEunchai Kang, Daniel A. Berg, Orion Furmanski, William M. Jackson, Yun Kyoung Ryu, Christy Gray, Cyrus David Mintz · 2016 · Neurotoxicology and Teratology
- Adult Hippocampal Neurogenesis in Alzheimer's Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory RecoveryS. Farioli-Vecchioli, Valentina Ricci, S. Middei · 2022 · Journal of Neural Transplantation and Plasticity
- The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's diseaseYuanhong Tang, Yan Yan, Jian Mao, Junjun Ni, Hong Qing · 2023 · Ageing Research Reviews
- Role of Calcitriol and Vitamin D Receptor (VDR) Gene Polymorphisms in Alzheimer’s DiseaseSoon Pyo Jeong, Niti Sharma, Seong Soo A. An · 2024 · International Journal of Molecular Sciences
- Apolipoprotein E Regulates Injury-Induced Activation of Hippocampal Neural Stem and Progenitor CellsSue J. Hong, Patricia M. Washington, Ahleum Kim, Cui-Ping Yang, Tzong‐Shiue Yu, Steven G. Kernie · 2015 · Journal of Neurotrauma
- Stem cell maintenance in the adult mammalian hippocampus: A matter of signal integration?Tobias J. Schwarz, Birgit Ebert, Dieter Chichung Lie · 2012 · Developmental Neurobiology
- The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathwayNaguib, Sarah, Lopez-Lee, Chloe, Torres, Eileen Ruth, Lee, Se-In, Zhu, Jingjie, Zhu, Daphne, Ye, Pearly, Norman, Kendra, Zhao, Mingrui, Wong, Man Ying et al. · 2025 · Immunity
- Borna Disease Virus Phosphoprotein Impairs the Developmental Program Controlling Neurogenesis and Reduces Human GABAergic NeurogenesisChloé Scordel, Alexandra Huttin, Marielle Cochet, Marion Szelechowski, Aurélie Poulet, Jennifer P. Richardson, Alexandra Benchoua, Daniel Gonzalez‐Dunia, Marc Éloit, Muriel Coulpier · 2015 · PLoS Pathogens
- Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's DiseaseYanfang Li, Zhicai Chen, Yue Gao, Gaojie Pan, Hong-Hua Zheng, Yun-Wu Zhang, Hua-Xi Xu, Guo-Jun Bu, Hui Zheng · 2017 · Journal of Neuroscience
- Apolipoprotein E regulates the maturation of injury-induced adult-born hippocampal neurons following traumatic brain injuryYacine Tensaouti, Tzong‐Shiue Yu, Steven G. Kernie · 2020 · PLoS ONE
- Synaptic Disruption by Soluble Oligomers in Patients with Alzheimer’s and Parkinson’s DiseaseBerenice A. Gutierrez, Agenor Limón · 2022 · Biomedicines
- The function of BMP4 during neurogenesis in the adult hippocampus in Alzheimer's diseaseHaiwei Xu, Wei Y. Huang, Yan‐Jiang Wang, Weizhong Sun, Jun Tang, Dabing Li, Pei Xu, Liang Guo, Zheng Qin Yin, Xiaotang Fan · 2012 · Ageing Research Reviews
- Somatostatin and the pathophysiology of Alzheimer’s diseaseVictor Nascimento Almeida · 2024 · Ageing Research Reviews
- The mechanisms underlying olfactory deficits in apolipoprotein E–deficient mice: focus on olfactory epithelium and olfactory bulbJiajia Zhang, Caiyuan Hao, Jinxiang Jiang, Yangjian Feng, Xi Chen, Ying Zheng, Jiawei Liu, Zhilin Zhang, Cheng Long, Li Yang · 2017 · Neurobiology of Aging
- Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding FunctionMyung‐Hoon Han, Eun-Hye Lee, Seong‐Ho Koh · 2016 · International Neurourology Journal
- Gene regulation in adult neural stem cells. Current challenges and possible applicationsJuan Manuel Encinas, Carlos Patricio Fitzsimons · 2017 · Advanced Drug Delivery Reviews
- Cerebrovascular Changes and Neurodegeneration Related to Hyperlipidemia: Characteristics of the Human ApoB-100 Transgenic MiceMelinda E. Tóth, Brigitta Dukay, Zsófia Hoyk, Miklós Sántha · 2020 · Current Pharmaceutical Design
- Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillationsJessica Brown, Elena Camporesi, Juan Lantero‐Rodriguez, Maria Olsson, Alice Wang, Blanca Medem, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari, Mark John Wall et al. · 2023 · Acta Neuropathologica Communications
- Crosstalk of metabolic factors and neurogenic signaling in adult neurogenesis: Implication of metabolic regulation for mental and neurological diseasesChong Gao, Qi Wang, Sookja Kim Chung, Jiangang Shen · 2017 · Neurochemistry International
- Epigenetic Modifications of GABAergic Interneurons Contribute to Deficits in Adult Hippocampus Neurogenesis and Depression-Like Behavior in Prenatally Stressed MiceZhong, Haiquan, Rong, Jing, Zhu, Chunting, Liang, Min, Li, Yingchun, Zhou, Rong · 2020 · International Journal of Neuropsychopharmacology
- Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer’s Disease: A Narrative ReviewHadeel Y. Tarawneh, Dona M. P. Jayakody, Hamid Reza Sohrabi, Ralph Nigel Martins, Wilhelmina H. A. M. Mulders · 2022 · Journal of Alzheimer s Disease Reports
- Sex Differences in Presynaptic Density and Neurogenesis in Middle-Aged ApoE4 and ApoE Knockout MiceAnne Rijpma, Diane Jansen, Ilse A.C. Arnoldussen, Xiaotian T. Fang, Maximilian Wiesmann, Martina P.C. Mutsaers, Pieter J.W.C. Dederen, Carola I.F. Janssen, Amanda J. Kiliaan · 2013 · Journal of Neurodegenerative Diseases
- Postnatal Loss of Hap1 Reduces Hippocampal Neurogenesis and Causes Adult Depressive-Like Behavior in MiceJianxing Xiang, Sen Yan, Shihua Li, Xiao‐Jiang Li · 2015 · PLoS Genetics
- Activity-dependent signaling mechanisms regulating adult hippocampal neural stem cells and their progenyAndrew Crowther, Juan Song · 2014 · Neuroscience Bulletin
- Expression of neurogenic markers in Alzheimer's disease: a systematic review and metatranscriptional analysisAriana P. Gatt, Hyun Ah Lee, Gareth Haydn Williams, Sandrine Thuret, Clive G. Ballard · 2019 · Neurobiology of Aging
- Epigenetic Regulation of Neural Stem Cells in Developmental and Adult StagesShu Kunoh, Hideyuki Nakashima, Kinichi Nakashima · 2024 · Epigenomes
- Hippocampal neurogenesis and pro‐neurogenic therapies for Alzheimer's diseaseJie Zheng · 2022 · Animal Models and Experimental Medicine
- Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cellsNaruyoshi Fujiwara, Jun Shimizu, Kenji Takai, Nagisa Nakata Arimitsu, Yuji Ueda, Sueshige Wakisaka, Suzuki Tomoko, Noboru Suzuki · 2015 · Experimental Neurology
- Activation of Developmental Nuclear Fibroblast Growth Factor Receptor 1 Signaling and Neurogenesis in Adult Brain by α7 Nicotinic Receptor AgonistSridhar Tatarao Narla, Ilona Klejbor, Barbara G. Birkaya, Yu‐Wei Lee, Janusz Moryś, Ewa K. Stachowiak, Dorota Prokop, Merouane Bencherif, Michal K. Stachowiak · 2013 · Stem Cells Translational Medicine
- APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoidsZhao, Jing, Ikezu, Tadafumi C., Lu, Wenyan, Macyczko, Jesse R., Li, Yonghe, Lewis-Tuffin, Laura J., Martens, Yuka A., Ren, Yingxue, Zhu, Yiyang, Asmann, Yan W. et al. · 2023 · Stem Cell Research & Therapy
- APOE3 - R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibitionNaguib, Sarah, Lopez-Lee, Chloe, Torres, Eileen Ruth, Lee, Se-In, Zhu, Jingjie, Zhu, Daphne, Ye, Pearly, Norman, Kendra, Zhao, Mingrui, Wong, Man Ying et al. · 2024
- Alzheimer’s Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic CompoundNarjes Baazaoui, Khalid Iqbal · 2022 · Biomolecules
- Molecular biomarkers and cognitive impairment in multiple sclerosis: State of the field, limitations, and future direction – A systematic review and meta-analysisTom-D. Rademacher, Sven Guenther Meuth, Heinz Wiendl, Andreas Johnen, Nils C. Landmeyer · 2023 · Neuroscience & Biobehavioral Reviews
- Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?Alexis Koutseff, Christophe Mittelhaeuser, Karim Essabri, Johan H. Auwerx, Hamid Méziane · 2013 · Brain Research
- Transplantation of GABAergic interneurons for cell-based therapyJulien Spatazza, Walter Mancia, Arturo Álvarez-Buylla · 2017 · Progress in brain research
- Molecular mechanisms of altered adult hippocampal neurogenesis in Alzheimer's diseaseHang Liu, Han Zhang, Ying Ma · 2021 · Mechanisms of Ageing and Development
- Myristic acid alleviates hippocampal aging correlated with GABAergic signalingQi Shang, Guifeng Chen, Peng Zhang, Wenhua Zhao, Honglin Chen, Die Yu, Fuyong Yu, Huiwen Liu, Xuelai Zhang, Jiahui He et al. · 2022 · Frontiers in Nutrition
- Association between apolipoprotein E gene polymorphism and mild cognitive impairment: a meta-analysisYunxia Jiang, Tao He, Wenshuai Deng, Peng Sun · 2017 · Clinical Interventions in Aging
- Attentional performance, impulsivity, and related neurotransmitter systems in apoE2, apoE3, and apoE4 female transgenic miceIngrid Reverte, Fiona Peris‐Sampedro, Pia Basaure, Leticia Campa, Cristina E. Sunol, Margarita Moreno, José L. Domingo, María Teresa Colomina · 2015 · Psychopharmacology
- Gabaergic Drugs and Alzheimer’s DiseaseAgenor Limón, Jorge Mauricio Reyes‐Ruiz, Ricardo Miledi · 2011 · Future Medicinal Chemistry
- The potential roles of excitatory-inhibitory imbalances and the repressor element-1 silencing transcription factor in aging and aging-associated diseasesIshan Ghosh, Celina S. Liu, Walter Swardfager, Krista L. Lanctôt, Nicole D. Anderson · 2021 · Molecular and Cellular Neuroscience
- Stearoyl-CoA desaturase-1: a potential therapeutic target for neurological disordersMelanie Loix, Sam Vanherle, Marta Turri, Stephan Kemp, Karl J. L. Fernandes, Jerome J. A. Hendriks, Jeroen F. J. Bogie · 2024 · Molecular Neurodegeneration
- APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoidsKarina K. Meyer-Acosta, Eva Díaz‐Guerra, Parul Varma, Adyasha Aruk, Sara Mirsadeghi, Aranis Muniz Perez, Yousef Rafati, Ali Hosseini, Vanesa Nieto‐Estévez, Michèle Giugliano et al. · 2025 · Stem Cell Reports
- Relationship between adult subventricular neurogenesis and Alzheimer’s disease: Pathologic roles and therapeutic implicationsHyeon Soo Kim, Seong Min Shin, Sujin Kim, Yunkwon Nam, Anji Yoo, M. Moon · 2022 · Frontiers in Aging Neuroscience
- Recent progress on the role of GABAergic neurotransmission in the pathogenesis of Alzheimer’s diseaseGhulam Abbas, Wajahat Mahmood, Nurul Kabir · 2016 · Reviews in the Neurosciences
- Beta-Amyloid (Aβ1-42) Increases the Expression of NKCC1 in the Mouse HippocampusPatricia Lam, Chitra Vinnakota, Beatriz Calvo‐Flores Guzmán, Julia Newland, Katie Peppercorn, Warren Perry Tate, Henry John Waldvogel, Richard L. M. Faull, Andrea Kwakowsky · 2022 · Molecules
- Compensatory remodeling of a septo-hippocampal GABAergic network in the triple transgenic Alzheimer’s mouse modelConnor M. Wander, Yadong Li, Hechen Bao, Brent Asrican, Yan‐Jia Luo, Heather A. Sullivan, Tzu-Hao Harry Chao, Weiting Zhang, Samantha Lucenell Chéry, Dalton S. Tart et al. · 2023 · Journal of Translational Medicine
- Vanillin improves scopolamine‑induced memory impairment through restoration of ID1 expression in the mouse hippocampusJae‑Chul Lee, In Hye Kim, Jeong-Hwi Cho, Tae‐Kyeong Lee, Joon Ha Park, Ji Hyeon Ahn, Bich Na Shin, Bing Chun Yan, Jongdai Kim, Yong Hwan Jeon et al. · 2018 · Molecular Medicine Reports
- Neuroregeneration: Regulation in Neurodegenerative Diseases and AgingН. В. Бобкова, Р. А. Полтавцева, Sergey V. Leonov, Gennady Tikhonovich Sukhikh · 2020 · Biochemistry (Moscow)
- Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer’s DiseaseCapsoni, Simona, Arisi, Ivan, Malerba, Francesca, D’Onofrio, Mara, Cattaneo, Antonino, Cherubini, Enrico · 2022 · Brain Sciences
- Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s diseaseDespoina Charou, Thanasis Rogdakis, Alessia Latorrata, María Valcárcel, Vasileios Papadogiannis, Christina Athanasiou, Alexandros Tsengenes, Maria Anna Papadopoulou, Dimitrios Lypitkas, Matthieu D. Lavigne et al. · 2024 · Stem Cell Research & Therapy
- The number of cysteine residues per mole in apolipoprotein E affects systematically synchronous neural interactions in women’s healthy brainsArthur C. Leuthold, Margaret Y. Mahan, John J. Stanwyck, Angeliki Georgopoulos, Apostolos P. Georgopoulos · 2013 · Experimental Brain Research
- Neural changes in Alzheimer’s disease from circuit to molecule: Perspective of optogeneticsQinghu Yang, Da Feng Song, Hong Qing · 2017 · Neuroscience & Biobehavioral Reviews
- Adult Hippocampal Neurogenesis and Alzheimer's Disease: Novel Application of Mesenchymal Stem Cells and their Role in Hippocampal Neurogenesis.Mahdi Noureddini, Saeid Bagheri-Mohammadi · 2021 · PubMed Central
- Aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in ratsYasunori Takahashi, Risako Yamashita, Hiromu Okano, Kazumi Takashima, Bunichiro Ogawa, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Gye‐Hyeong Woo, Toshinori Yoshida et al. · 2021 · Toxicology
- Female mice with apolipoprotein E4 domain interaction demonstrated impairments in spatial learning and memory performance and disruption of hippocampal cyto-architectureSamuel Olusegun Adeosun, Xu Hou, Lili Shi, Craig A. Stockmeier, Baoying Zheng, Robert L. Raffaı̈, Karl Heinrich Weisgraber, Thomas H. Mosley, Jun Ming Wang · 2019 · Neurobiology of Learning and Memory
- Epidermal growth factor treatment of female mice that express APOE4 at an age of advanced pathology mitigates behavioral and cerebrovascular dysfunctionSteve Zaldua, Frederick C. Damen, Rohan Pisharody, Riya Thomas, Kelly D. Fan, Giri K. Ekkurthi, Sarah B. Scheinman, Sami Alahmadi, Felecia M. Marottoli, Simon T. Alford et al. · 2020 · Heliyon
- Waveform-based classification of dentate spikesRodrigo M.M. Santiago, Vítor Lopes‐dos‐Santos, Emily A Aery Jones, Yadong Huang, David Dupret, Adriano B. L. Tort · 2024 · Scientific Reports
- TREM2 Alleviates Neuroinflammation and Improves Neurogenesis in ApoE−/− Mice by Regulating M1/M2 Microglial PolarizationXiaoqian Peng, Zi-Kang Yang, Hongsong Guo, Xiangyuan Wu, John Bosco Ruganzu, Zhong-zhong Liu, Song-Di Wu, Wei-Na Yang · 2025 · Molecular Neurobiology
- Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic TargetingKarin E. Sandoval, KEN A. WITT · 2024 · Pharmacological Reviews
- Progressive disruption of neurodevelopment by mid‐gestation exposure to lipopolysaccharides and the ameliorating effect of continuous alpha‐glycosyl isoquercitrin treatmentHiromu Okano, Kazumi Takashima, Yasunori Takahashi, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Xinyu Zou, Mihoko Koyanagi, Robert R. Maronpot, Toshinori Yoshida et al. · 2022 · Environmental Toxicology
- Alzheimer's disease phenotype based upon the carrier status of the apolipoprotein E ɛ4 alleleXiaoyu Ji, Xinyuan Peng, Hailiang Tang, Hui Pan, W.D. Wang, Jie Wu, Jian Chen, Naili Wei · 2023 · Brain Pathology
- The neurogenic niche in Alzheimer’s diseaseConnor M. Wander, Juan Song · 2021 · Neuroscience Letters
- Adult Neurogenesis Is Altered by GABAergic Imbalance in Models of Alzheimer's DiseaseAlejandro Fabián Schinder, Nicolás A. Morgenstern · 2009 · Cell stem cell
- Excitation–inhibition homeostasis in Alzheimer’s disease: a selective multiscale review of mechanisms, sex differences, and therapeutic opportunitiesAndrew P. Burns, Monica I. Duran, Igor Fortel, Orly Lazarov, Liang Zhan, Barbara B. Bendlin, Alex Leow · 2026 · Neuropsychopharmacology
- Neuronal Transplantation for Alzheimer’s Disease and Prospects for Generating Exogenic Neurons as a Source of Cells for ImplantationPhoebe Strell, Sether T. Johnson, Chris Carchi, Walter C. Low · 2023 · Cell Transplantation
- Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypesAmy Christensen, Cassandra Joan McGill, Wenjie Qian, Christian J. Pike · 2024 · Frontiers in Aging Neuroscience
- Targeting ApoE–KCC2 Signaling Rescues GABAergic Synaptic Dysfunction and Depression-like Behaviors in MiceChengyuan Xu, Jing Liu, Mengru Guo, Jia Wang, Xianbing Bai, Chenlei Zhang, Xinyue Luan, Huailong Pei, Huan Liu, Xinyou Lv et al. · 2025 · Research
- TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's DiseaseZhongzhao Guo, Hong Ni, Lu Yu, Zhengyu Cui, Yixing Wang, Zilu Zhu, Xinyu Wei, Chenyi Xia, Ming Xu, Lixia Du et al. · 2025 · Advanced Science
- Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s DiseaseXi Richard Chen, Yongzhao Shao, Martin J. Sadowski, on behalf of the Alzheimer’s Disease Neuroimaging Initiative · 2023 · Genes
- The Adult Neurogenesis Theory of Alzheimer’s DiseaseCarlo Abbate · 2023 · Journal of Alzheimer s Disease
- Delayed dendritic development in newly generated dentate granule cells by cell-autonomous expression of the amyloid precursor proteinNicolás A. Morgenstern, Damiana Giacomini, Gabriela Lombardi, Eduardo Miguel Castaño, Alejandro Fabián Schinder · 2013 · Molecular and Cellular Neuroscience
- Sex and sex hormone differences in hippocampal neurogenesis and their relevance to Alzheimer’s diseaseBonnie H. Lee, Tanvi A. Puri, Liisa A.M. Galea · 2021 · Elsevier eBooks
- In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesisHyun-Ah Lee, Jack Price, Deepak P. Srivastava, Sandrine Thuret · 2023 · Hippocampus