Correction of a genetic disease in mouse via use of CRISPR-Cas9

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Items 301–400 of 620

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4. Through the Cat-Map Gateway: A Brief History of Cataract Genetics
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5. Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice
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6. A Tandem Guide RNA-Based Strategy for Efficient CRISPR Gene Editing of Cell Populations with Low Heterogeneity of Edited Alleles
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7. Genetically engineered birds; pre-CRISPR and CRISPR era
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8. CRISPR-Cas9 Technology for the Creation of Biological Avatars Capable of Modeling and Treating Pathologies: From Discovery to the Latest Improvements
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9. CRISPR/Cas genome editing system and its application in potato
   Xin Hou, Xiaomeng Guo, Yan Zhang, Qiang Zhang · 2023 · Frontiers in Genetics
10. CRISPR/Cas9 technology: applications in oocytes and early embryos
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11. ACOT4 accumulation via AKT-mediated phosphorylation promotes pancreatic tumourigenesis
    Chenming Ni, Kailian Zheng, Yunshu Gao, Ying Chen, Keqing Shi, Can-rong Ni, Gang Jin, Guanzhen Yu · 2020 · Cancer Letters
12. Application of CRISPR/Cas Technology in Spermatogenesis Research and Male Infertility Treatment
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13. Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer’s disease
    Li, Yu, Xu, Min, Xiang, Bo-Lin, Li, Xiao, Zhang, Deng-Feng, Zhao, Hui, Bi, Rui, Yao, Yong-Gang · 2023 · Neuropsychopharmacology
14. Trait Loss in Evolution: What Cavefish Have Taught Us about Mechanisms Underlying Eye Regression
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15. Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
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16. CRISPR technology for gene therapy
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17. Induced Pluripotent Stem Cells Derived from Alzheimer’s Disease Patients: The Promise, the Hope and the Path Ahead
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18. Applications of CRISPR genome editing technology in drug target identification and validation
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19. CRISPR-Cas9-Mediated Gene Editing in Mouse Spermatogonial Stem Cells
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20. Synthetic biology strategies towards the development of new bioinspired technologies for medical applications
    Joana L. Rodrigues, Débora Ferreira, Lígia R. Rodrigues · 2016 · Elsevier eBooks
21. Utilising polymorphisms to achieve allele-specific genome editing in zebrafish
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22. CRISPR/Cas9 Edited Induced Pluripotent Stem Cell-Based Vascular Tissues to Model Aging and Disease-Dependent Impairment
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23. In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers
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24. CRISPR-Cas9 Genome Engineering: Trends in Medicine and Health
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25. Spinal cord injury induced neuropathic pain: Molecular targets and therapeutic approaches
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26. Efficient gene correction of an aberrant splice site in β‐thalassaemia iPSCs by CRISPR/Cas9 and single‐strand oligodeoxynucleotides
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27. Disrupting the male germ line to find infertility and contraception targets
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28. ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid RPE1 and HCT116 cells
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29. Neuroprotective therapies in glaucoma: II. Genetic nanotechnology tools
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30. ANGPTL3 impacts proteinuria and hyperlipidemia in primary nephrotic syndrome
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31. CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons
    Guoxu Song, Yuying Ma, Xing Gao, Xuewen Zhang, Fei Zhang, Chunhong Tian, Jiajia Hou, Zheng Liu, Zixin Zhao, Yong Tian · 2022 · Life Medicine
32. Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation
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33. Viral Cre-LoxP tools aid genome engineering in mammalian cells
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34. ‘Artificial spermatid’-mediated genome editing†
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35. Technical advances contribute to the study of genomic imprinting
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36. 多样化CRISPR技术在动物体内基因编辑研究中的应用和进展
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37. Visualization Analysis of CRISPR Gene-editing Knowledge Map based on Citespace
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38. Gene surgery
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39. Efficient Zygotic Genome Editing via RAD51-Enhanced Interhomolog Repair
    Jonathan J. Wilde, Tomomi Aida, Martin Wienisch, Qiangge Zhang, Peimin Qi, Guoping Feng · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
40. CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential
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41. In vivoandin vitrodisease modeling with CRISPR/Cas9
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42. Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock
    Yuguo Yuan, Song-Zi Liu, Muhammad Farhab, Mei-Yun Lv, Ting Zhang, Shao-Xiao Cao · 2024 · Functional & Integrative Genomics
43. Precision in Action: The Role of Clustered Regularly Interspaced Short Palindromic Repeats/Cas in Gene Therapies
    Amrutha Banda, Olivia Impomeni, Aparana Singh, Abdul Rasheed Baloch, Wenhui Hu, Dabbu Kumar Jaijyan · 2024 · Vaccines
44. The CRISPR-Cas System and Clinical Applications of CRISPR-Based Gene Editing in Hematology with a Focus on Inherited Germline Predisposition to Hematologic Malignancies
    Rina Kansal · 2024 · Genes
45. Correcting genetic defects with CRISPR–Cas9
    Isabel B. Lokody · 2013 · Nature Reviews Genetics
46. A stable but reversible integrated surrogate reporter for assaying CRISPR/Cas9-stimulated homology-directed repair
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47. Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice
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48. Valproic Acid Significantly Improves CRISPR/Cas9-Mediated Gene Editing
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49. Functional Comparison between VP64-dCas9-VP64 and dCas9-VP192 CRISPR Activators in Human Embryonic Kidney Cells
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50. A Prospective Treatment Option for Lysosomal Storage Diseases: CRISPR/Cas9 Gene Editing Technology for Mutation Correction in Induced Pluripotent Stem Cells
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51. Site-specific genome editing in treatment of inherited diseases: possibility, progress, and perspectives
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52. Developmental history and application of CRISPR in human disease
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53. Haploid embryonic stem cells can be enriched and maintained by simple filtration
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54. Gene Therapy of Adult Neuronal Ceroid Lipofuscinoses with CRISPR/Cas9 in Zebrafish
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55. Speciation and adaptation research meets genome editing
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56. Genome editing and bioinformatics
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57. Genome-wide mapping of protein–DNA damage interaction by PADD-seq
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58. Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer
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61. Efficient Delivery of Plasmid DNA Using Incorporated Nucleotides for Precise Conjugation of Targeted Nanoparticles
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62. CRISPR links to long noncoding RNA function in mice: A practical approach
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63. Expansion of the CRISPR/Cas Genome-Sculpting Toolbox: Innovations, Applications and Challenges
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64. An extensive review to facilitate understanding of CRISPR technology as a gene editing possibility for enhanced therapeutic applications
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65. THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration
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66. Advanced synthetic routes of metal organic frameworks and their diverse applications
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67. Gene editing therapy for cardiovascular diseases
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68. Small-molecule compounds boost genome-editing efficiency of cytosine base editor
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69. Development and Clinical Evaluation of a CRISPR-Based Diagnostic for Rapid Group BStreptococcusScreening
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70. Integrative Analysis of CRISPR/Cas9 Target Sites in the HumanHBBGene
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71. Application of CRISPR-Cas system in gene therapy: Pre-clinical progress in animal model
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72. Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system
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73. Application of CRISPR-Cas9 in eye disease
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74. CRISPR/Cas systems usher in a new era of disease treatment and diagnosis
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75. Production of genome-edited pluripotent stem cells and mice by CRISPR/Cas [Review]
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76. Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery
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77. Concise Review: Getting to the Core of Inherited Bone Marrow Failures
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78. Generation of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer
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79. An Agrobacterium-Mediated CRISPR/Cas9 Platform for Genome Editing in Maize
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80. Recent advances in stem cells and gene editing: Drug discovery and therapeutics
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81. Identification and Evolution of Cas9 tracrRNAs
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82. The role of the CRISPR‐Cas system in cancer drug development: Mechanisms of action and therapy
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83. Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist’s perspective
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84. RNA circuits and RNA-binding proteins in T cells
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85. A suicidal zinc finger nuclease expression coupled with a surrogate reporter for efficient genome engineering
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86. RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes
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87. Generation of Human Embryonic Stem Cell Line Expressing zsGreen in Cholinergic Neurons Using CRISPR/Cas9 System
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88. Efficient generation of FVII gene knockout mice using CRISPR/Cas9 nuclease and truncated guided RNAs
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89. Modern Prometheus: editing the human genome with Crispr-Cas9
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90. Efficient genome editing in wild strains of mice using the i-GONAD method
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91. Development and challenges of using CRISPR-Cas9 system in mammalians
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92. CRISPR: a journey of gene-editing based medicine
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93. Genome editing: An essential technology for cancer treatment
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94. Modeling craniofacial and skeletal congenital birth defects to advance therapies
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95. Genome Editing Using Crispr/Cas System: New Era Genetic Technology in Agriculture to Boost Crop Output
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96. Mucosal RNA and protein expression as the next frontier in IBS: abnormal function despite morphologically intact small intestinal mucosa
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97. CRISPR/Cas9 in allergic and immunologic diseases
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98. CRISPR‐Cas Biochemistry and CRISPR‐Based Molecular Diagnostics
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99. Efficient generation of the mouse model with a defined point mutation through haploid cell-mediated gene editing
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100. CRISPR/Cas9, a universal tool for genomic engineering
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