Chromatin Repressive Complexes in Stem Cells, Development, and Cancer

Laugesen, Anne, Helin, Kristian·2014·Cell stem cell

DOI 10.1016/j.stem.2014.05.006

Cited by (354)

Items 201–300 of 354

A review of the therapeutic potential of histone deacetylase inhibitors in rhabdomyosarcoma
Omar A. Selim, Clara H. Song, Amy Edalji Kumar, Rebecca Phelan, Arun S. Singh, Noah C. Federman · 2023 · Frontiers in Oncology
Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains
Bryan, Elana, Valsakumar, Devisree, Idigo, Nwamaka J., Warburton, Marie, Webb, Kimberly M., McLaughlin, Katy A., Spanos, Christos, Lenci, Simone, Major, Viktoria, Ambrosi, Christina et al. · 2025 · Molecular Cell
FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway
Xiujuan Zhao, Xing Wang, Qian Li, Wanbiao Chen, Na Zhang, Yu Kong, Junqiang Lv, Lei Cao, Dan Lin, Xi Wang et al. · 2018 · Cell Death and Disease
HDAC9 exacerbates myocardial infarction via inactivating Nrf2 pathways
Fan Liu, Yali Di, Wei Ma, Xiaoli Kang, Xia Li, Zheng Ji · 2021 · Journal of Pharmacy and Pharmacology
Gender-specific genetic and epigenetic signatures in cardiovascular disease
Justin Bridges, Jose A. Ramirez-Guerrero, Manuel Rosa‐Garrido · 2024 · Frontiers in Cardiovascular Medicine
Epigenetic therapy and dermatologic disease: moving beyond CTCL
Joshua S. Mervis, Jean S. McGee · 2018 · Journal of Dermatological Treatment
Targeting epigenetic mechanisms to overcome venetoclax resistance
Gabriel Prado, Charlotte Leonie Kaestner, Jonathan D. Licht, Richard Lynn Bennett · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Drugging the Epigenome: Overcoming Resistance to Targeted and Immunotherapies in Melanoma
Ailish M. Hanly, Frederick Thomas Gibson, Sarah E. Nocco, Samantha Rogers, Muzhou Wu, Rhoda M. Alani · 2021 · JID Innovations
RBBP4 dysfunction reshapes the genomic landscape of H3K27 methylation and acetylation and disrupts gene expression
Weipeng Mu, Noel S. Murcia, Keriayn N. Smith, Debashish U. Menon, Della Yee, Terry Magnuson · 2022 · G3 Genes Genomes Genetics
Activin/Smad2 and Wnt/β-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells
Xuanhao Xu, Lu Wang, Bofeng Liu, Wei Xie, Ye‐Guang Chen · 2018 · Journal of Biological Chemistry
Transcriptome Analysis of Schwann Cells at Various Stages of Myelination Implicates Chromatin Regulator Sin3A in Control of Myelination Identity
Bin Zhang, Wenfeng Su, Junxia Hu, Jinghui Xu, Parizat Askar, Shuangxi Bao, Songlin Zhou, Gang Chen, Yun Gu · 2022 · Neuroscience Bulletin
KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors
Bo Zhang, Chen Ning Zhao, Wenchen Shen, Wei Li, Yue Zheng, Xiangfei Kong, Junbao Wang, Xudong Wu, Tao Zeng, Ying Liu et al. · 2023 · Nature Communications
Zscan4 mediates ubiquitination and degradation of the corepressor complex to promote chromatin accessibility in 2C-like cells
Jiao Yang, Jiameng Dan, Nannan Zhao, Linlin Liu, Huasong Wang, Qiangqiang Liu, Lingling Wang, Jie Li, Yiwei Wu, Feilong Chen et al. · 2024 · Proceedings of the National Academy of Sciences
Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells.
Dashzeveg Bayarsaihan · 2016 · Europe PMC (PubMed Central)
Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis
Carmela Calés, Leticia Pavón, Katarzyna Starowicz, Claudia Pérez‐Martínez, Mónica Bravo, Tomokatsu Ikawa, Haruhiko Koseki, Miguel Vidal · 2015 · Molecular and Cellular Biology
Polycomb repressive complex 2 haploinsufficiency identifies a high-risk subgroup of pediatric acute myeloid leukemia
Jonathan Bond, Elise Boudry Labis, Alice Marceau‐Renaut, Nicolas Duployez, Myriam Labopin, Guillaume Hypolite, Gérard Michel, Stéphane Ducassou, Hélène Boutroux, Brigitte Nelken et al. · 2018 · Leukemia
Small Molecule GSK-J1 Affects Differentiation of Specific Neuronal Subtypes in Developing Rat Retina
Reza Raeisossadati, Marília Inês Móvio, Lais Takata Walter, Silvia Honda Takada, Carolina Beltrame Del Debbio, Alexandre Hiroaki Kihara · 2018 · Molecular Neurobiology
Dual repression of endocytic players by ESCC microRNAs and the Polycomb complex regulates mouse embryonic stem cell pluripotency
Ridim Dadasaheb Mote, Gaurang Mahajan, Anup Padmanabhan, Ramaraju Ambati, Deepa Subramanyam · 2017 · Scientific Reports
Chromatin Bottlenecks in Cancer
Jay F. Sarthy, Steven Henikoff, Kami Ahmad · 2019 · Trends in cancer
PHF6 promotes the progression of endometrial carcinoma by increasing cancer cells growth and decreasing T‐cell infiltration
Xiaomin Wang, Aizhong Fang, Yichen Peng, Jianyu Yu, Chunna Yu, Jinxuan Xie, Yi Zheng, Lairong Song, Parker Li, Jia Li et al. · 2023 · Journal of Cellular and Molecular Medicine
The emerging roles of long noncoding RNAs in lymphatic vascular development and disease
Konstantin I. Ivanov, Olga V. Samuilova, Andrey A. Zamyatnin · 2023 · Cellular and Molecular Life Sciences
Polycomb repressive complex 2 (PRC2) pathway’s role in cancer cell plasticity and drug resistance
Pouya Goleij, Mohammad Mahdi Heidari, Mohammad Amin Khazeei Tabari, Mahboube Hadipour, Aryan Rezaee, Alireza Javan, Pantea Majma Sanaye, Danaè S. Larsen, Maria Daglia, Haroon Khan · 2025 · Functional & Integrative Genomics
Charting Developmental Dissolution of Pluripotency
Joerg Betschinger · 2016 · Journal of Molecular Biology
RAS and PP2A activities converge on epigenetic gene regulation
Anna Aakula, Mukund Sharma, Francesco Tabaro, Reetta Nätkin, Jesse Kamila, Henrik Honkanen, Matthieu Schapira, C.H. Arrowsmith, Matti Nykter, Jukka K. Westermarck · 2023 · Life Science Alliance
Control of adult intestinal identity by the Polycomb repressive machinery
Fulvio Chiacchiera, Diego Pasini · 2016 · Cell Cycle
Single-cell analysis of chromatin silencing programs in development and tumor progression
Steven J. Wu, Scott N. Furlan, Anca B. Mihalas, Hatice S Kaya-Okur, Abdullah Hamid Feroze, Samuel Emerson, Ye Zheng, Kalee Carson, Patrick Joseph Cimino, Christopher Dirk Keene et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation
Ting Li, Yingying Zhao, Qian Li, Zhaoran Sun, Ni Wang, Liangyu Xing, Nan Tang, Runyuan Mao, Yuxin Wang, Jiacheng Su et al. · 2025 · Molecular Cell
Ancestral function but divergent epigenetic regulation of HAIKU2 reveals routes of seed developmental evolution
Di Wu, Yiming Wei, Xiang Zhao, Boka Li, Huankai Zhang, Gang Xu, Juntong Lv, Dajian Zhang, Xiansheng Zhang, Min Ni · 2022 · Molecular Plant
CoREST1 Promotes Tumor Formation and Tumor Stroma Interactions in a Mouse Model of Breast Cancer
Sohini Mazumdar, Lisa M. Arendt, Sarah M. Phillips, Maja Sedic, Charlotte Kuperwasser, Grace Gill · 2015 · PLoS ONE
Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft
Nataly Tarasenko, Abraham Nudelman, Gabriela Rozic, Suzanne M. Cutts, Ada Rephaeli · 2017 · Investigational New Drugs
Genetic interaction between Gli3 and Ezh2 during limb pattern formation
Steven J. Deimling, Kimberly M. Lau, Chi‐chung Hui, Sevan Hopyan · 2018 · Mechanisms of Development
Gene expression profile of a selection of Polycomb Group genes during zebrafish embryonic and germ line development
Naomi D. Chrispijn, Karolina M. Andralojc, Charlotte Castenmiller, Leonie M. Kamminga · 2018 · PLoS ONE
3-Deazaneplanocin A suppresses aggressive phenotype-related gene expression in an oral squamous cell carcinoma cell line
Mitsutoki Hatta, Kaori Naganuma, Kenichi Kato, Jun Yamazaki · 2015 · Biochemical and Biophysical Research Communications
The Role of Chromatin-Associated Proteins in Cancer
Kristian Helin, Saverio Minucci · 2016 · Annual Review of Cancer Biology
BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate
Ruiqi Liu, Yonglin Peng, Wenfei Du, Yunqiang Wu, Wen Zhang, Congxia Hu, Min Liu, Xinhua Liu, Ji Wu, Jielin Sun et al. · 2023 · Frontiers in Cell and Developmental Biology
LncRNA affects epigenetic reprogramming of porcine embryo development by regulating global epigenetic modification and the downstream gene SIN3A
Daoyu Zhang, Yongfeng Zhou, Rong Huang, Yanhui Zhai, Di Wu, Xinglan An, Sheng Zhang, Lijing Shi, Qi Li, Xiangjie Kong et al. · 2022 · Frontiers in Physiology
Recapitulation of patient-specific 3D chromatin conformation using machine learning
Duo Xu, Andre Neil Forbes, Sandra M. Cohen, Ann C. Palladino, Tatiana Karadimitriou, Ekta Khurana · 2023 · Cell Reports Methods
A Critical Analysis of the FDA’s Omics-Driven Pharmacodynamic Biomarkers to Establish Biosimilarity
Sarfaraz K. Niazi · 2023 · Pharmaceuticals
Regulation of keratinocyte proliferation and differentiation by secoiridoid oleacein in monoculture and fibroblast co-culture models
Juhee Cho, Meriem Bejaoui, Hiroko Isoda · 2025 · Biomedicine & Pharmacotherapy
Lysines Acetylome and Methylome Profiling of H3 and H4 Histones in Trichostatin A—Treated Stem Cells
Flora Cozzolino, Ilaria Iacobucci, Vittoria Monaco, Tiziana Angrisano, Maria Monti · 2021 · International Journal of Molecular Sciences
Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development
Venkata Thulabandu, Timothy E Nehila, James W. Ferguson, Radhika P. Atit · 2021 · Developmental Biology
Epigenetic Derepression of PROX1 Promotes Neuroendocrine Prostate Cancer Progression
Varadha Balaji Venkadakrishnan, Adam G. Presser, Nathaniel C.E. Voss, James V. Neiswender, Lisa Brenan, Keira Prenza Sosa, Kenny Weng, Andres Martin Acosta, Francisca Vázquez, Himisha Beltran · 2025 · Cancer Research
Chromatin Remodulator CHD4: A Potential Target for Cancer Interception
Krishnendu Goswami, Karthikkumar Venkatachalam, Surya Pratap Singh, Chinthalapally V. Rao, Venkateshwar Madka · 2025 · Genes
Barhl2 maintains T-cell factors as repressors, and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation
Elena Sena, Nathalie Rocques, Caroline Borday, Harem Sabr Muhamad Amin, Karine Parain, David Sitbon, Albert Chesneau, Béatrice Durand · 2019 · Development
SIN3A Regulates Porcine Early Embryonic Development by Modulating CCNB1 Expression
Lei Luo, Yanna Dang, Yan Shi, Panpan Zhao, Yunhai Zhang, Kun Zhang · 2021 · Frontiers in Cell and Developmental Biology
Nuclear Coregulatory Complexes in Tregs as Targets to Promote Anticancer Immune Responses
Lanette M. Christensen, Wayne W. Hancock · 2022 · Frontiers in Immunology
Essential role of MESP1-RING1A complex in cardiac differentiation
Qianqian Liang, Siqing Wang, Xinyan Zhou, Yongbo Li, Shenghui Xing, Yi’ou Sha, Fuling Yang, Wenjun Huang, Nanbo Liu, Zhetao Li et al. · 2022 · Developmental Cell
Expression of the Neural REST/NRSF–SIN3 Transcriptional Corepressor Complex as a Target for Small-Molecule Inhibitors
Sakthidasan Jayaprakash, Le Thi My Le, Bjoern Ole Sander, Monika M. Golas · 2020 · Molecular Biotechnology
Tazemetostat, an EZH2 inhibitor, in solid tumors harboring SWI/SNF alterations: a phase II basket study
Mrinal M. Gounder, Patrick Schöffski, Robin L. Jones, Silvia Stacchiotti, George D. Demetri, Gregory Michael Cote, Mark Agulnik, Rashmi K Chugh, Thierry Marie Jahan, Abha A. Gupta et al. · 2026 · Nature Communications
Biological Functions of the KDM2 Family of Histone Demethylases
Jaclyn Andricovich, Alexandros Tzatsos · 2023 · Advances in experimental medicine and biology
CBX4 regulation of senescence and associated diseases: Molecular pathways and mechanisms
Qianxing Hu, Linming Su, Wanli Zhao, Yinuo Jin, Liang Jin, Yue Yang, Fangfang Zhang · 2025 · Pharmacological Research
Histone profiles in cancer
Simone Stefanie Riedel, Tobias Neff, Kathrin Maria Bernt · 2015 · Pharmacology & Therapeutics
A rapidly evolved domain, the SCML2 DNA-binding repeats, contributes to chromatin binding of mouse SCML2†
So Maezawa, Kris G. Alavattam, Mayu Tatara, Rika Nagai, Artem Barski, Satoshi H. Namekawa · 2018 · Biology of Reproduction
Polycomb Repressive Complex 2: a Dimmer Switch of Gene Regulation in Calvarial Bone Development
Timothy E Nehila, James W. Ferguson, Radhika P. Atit · 2020 · Current Osteoporosis Reports
CBX2 suppresses interferon signaling to diminish tumor immunogenicity via a noncanonical corepressor complex
Yanxun Lin, Huan Jin, Yong She, Yiqun Zhang, Lei Cui, Chunyuan Xie, Yongxiang Liu, Huanling Zhang, Hui Guo, Jiaxin Wu et al. · 2025 · Proceedings of the National Academy of Sciences
PJA2 Suppresses Colorectal Cancer Progression by Controlling HDAC2 Degradation and Stability
Zhihao Chen, Chaofan Peng, Chi Jin, Ye Wang, Tuo Wang, Peng Yang, Wen Peng, Qingyang Sun, Hengjie Xu, Hongxu Nie et al. · 2025 · Advanced Science
Targeted disruption of PRC1.1 complex enhances bone remodeling
Liangyu Xing, Jinxin Xu, Meihan Gong, Y. Liu, Xuanyuan Li, Lingyu Meng, Ruyue Du, Ying Zhou, Zhaoguang Ouyang, Xu Liu et al. · 2025 · Nature Communications
Epigenetic mechanisms involved in modulation of inflammatory diseases
Dashzeveg Bayarsaihan · 2016 · Current Opinion in Clinical Nutrition & Metabolic Care
Relating protein functional diversity to cell type number identifies genes that determine dynamic aspects of chromatin organisation as potential contributors to organismal complexity
Daniela Lopes Cardoso, Colin R. Sharpe · 2017 · PLoS ONE
Control of the Gene Activity by Polycomb and Trithorax Group Proteins in , "Генетика"
Darya Chetverina, P. V. Elizar’ev, Д. В. Ломаев, Pavel G Georgiev, Maksim Erokhin · 2017 · Генетика
CBX Family Members in Two Major Subtypes of Renal Cell Carcinoma: A Comparative Bioinformatic Analysis
Anna Grimaldi, Ornella Affinito, Marco Salvatore, Monica Franzese · 2022 · Diagnostics
NSPc1 polycomb protein complex binds and cross‑talks to lncRNAs in glioma H4 cells
Yuliang Wang, Zhikong Liang, Hui Li, Jinglong Tao, Yi Sun, Yanhua Gong · 2019 · Oncology Reports
Comment on “Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2”
Ying Zhang, Neil Justin, Jon R. Wilson, Steve J. Gamblin · 2016 · Science
The role of aberrant proteolysis in lymphomagenesis
Anagh Anant Sahasrabuddhe, Kojo S.J. Elenitoba‐Johnson · 2015 · Current Opinion in Hematology
Polycomb and Trithorax factors in transcriptional and epigenetic regulation
Priscilla Nga Ieng Lau, Chi Wai Eric So · 2015 · Elsevier eBooks
The Tumor Suppressive Role of PATZ1 in Thyroid Cancer: A Matter of Epithelial-Mesenchymal Transition
Monica Fedele, Laura Cerchia · 2016 · Chemotherapy Open access
Zebrafish Polycomb repressive complex-2 critical roles are largely Ezh2- over Ezh1-driven and concentrate during early embryogenesis
Gabriel A. Yette, Scott Stewart, Kryn Stankunas · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy
Felicity J. Ashcroft, Asimina Bourboula, Nur Mahammad, Efrosini Barbayianni, Astrid Jullumstrø Feuerherm, Thanh Thuy Nguyen, Daiki Hayashi, Maroula G. Kokotou, Konstantinos Alevizopoulos, Edward A. Dennis et al. · 2025 · Nature Communications
Xuanbai Chengqi Decoction alleviates lipopolysaccharide-induced acute lung injury by regulating the EZH2/EGR1/TXNIP signaling pathway
Suwan Wu, Zhiqiang Yan, Tao Guo, Wantao Wang, Ziming Huang, Huahe Zhu, Shun Wang, Jiayun Wang, Liangbo Jiao, Zhongju Xu et al. · 2025 · Journal of Ethnopharmacology
Polycomb group genes are required to maintain a binary fate choice in the Drosophila eye
Jennifer K. Finley, Adam C. Miller, Tory G. Herman · 2015 · Neural Development
Fsh–Pc–Sce complex mediates active transcription of Cubitus interruptus (Ci)
Xiangdong Lv, Hao Chen, Shuo Zhang, Zhao Zhang, Chenyu Pan, Yuanxin Xia, Jialin Fan, Wenqing Wu, Yi Lu, Lei Zhang et al. · 2018 · Journal of Molecular Cell Biology
Regulation of Histone Acetylation on Expression Profiles of Potassium Channels During Cardiomyocyte Differentiation From Mouse Embryonic Stem Cells
Duo Wang, Chang Liu, Zhigang Li, Yumei Wang, Wenjing Wang, Xiujuan Wu, Kang Wang, Wei Miao, Li Li, Luying Peng · 2017 · Journal of Cellular Biochemistry
Plant homeodomain finger protein 6 in the regulation of normal and malignant hematopoiesis
Satoru Miyagi, Atsushi Iwama · 2020 · Current Opinion in Hematology
PcG Proteins in Caenorhabditis elegans
Baris Tursun · 2017 · Elsevier eBooks
Ring shape Golden Ratio multicellular structures are algebraically afforded by asymmetric mitosis and one to one cell adhesion
William E. Butler, Thomas Bernard Kinane · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Regulation of human development by ubiquitin chain editing of chromatin remodelers
David B. Beck, Mohammed Abul Basar, Anthony J. Asmar, Joyce J. Thompson, Hirotsugu Oda, Daniela Tiaki Uehara, Ken Saida, Precilla D’Souza, Joann Norma Bodurtha, Weiyi Mu et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets
Duo Xu, Andre Neil Forbes, Sandra M. Cohen, Ann C. Palladino, Tatiana Karadimitriou, Ekta Khurana · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress
Neekkan Dey, Constantinos Koumenis, Davide Ruggero, Serge Yu. Fuchs, John Alan Diehl · 2024 · Molecular Cancer Research
Cancer Stem Cells as Therapeutic Targets
Shinji Tanaka · 2016 · Royal Society of Chemistry eBooks
Individual capacity for repair of DNA damage and potential uses of stem cell lines for clinical applications: a matter of (genomic) integrity
Rumena Petkova, Nikolai Zhelev, Roumen G. Pankov, Stoyan Chakarov · 2018 · Biotechnology & Biotechnological Equipment
Muscles cannot break a NuRDy heart
Barbora Malecová, Alessandra Dall’Agnese, Prem Puri · 2016 · The EMBO Journal
Engineering Cell Fate: The Roles of iPSC Transcription Factors, Chemicals, Barriers and Enhancing Factors in Reprogramming and Transdifferentiation
Behnam Ebrahimi · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
Discovery of genes required for body axis and limb formation by global identification of retinoic acid regulated epigenetic marks
Marie Berenguer, Karolin F. Meyer, Jun Yin, Gregg Duester · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells
Yogesh Kumar, Pratibha Tripathi, Pushkar Dakle, Majid Mehravar, Varun K. Pandey, Michael J. Bullen, Zhongming Zhang, Dhaval Hathiwala, Marc A. Kerenyi, Andrew J. Woo et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Integrated analysis of single-cell and transcriptome based RNA-seq multilayer network and WGCNA for construction and validation of an immune cell-related prognostic model in clear cell renal cell carcinoma
Guanlin Wu, Weiming Guo, Shuai Zhu, Gang Fan · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Interaction and regulatory expression of Polycomb and NuRD complexes in mouse embryonic stem cell under PKC inhibition
Fangfang Wu, Zhihui Liu, Jing Li Huang, Yuan Gao, Lan Yang, Fuliang Du · 2025 · Scientific Reports
HP1 enhances radio- and chemotherapy resistance in osteosarcoma via PARP1-dependent transcriptional repression and HR repair
Yuanxin Zhu, Wenjia Li, Yuntan Qiu, Zhihuai Deng, Yu Li, Hengxing Chen, J. Zhang, Daning Lu, Kaishun Hu, Dongsheng Huang et al. · 2025 · Cancer Letters
Coming to light: the transcriptional regulatory roles of histone lysine crotonylation in health and disease
Shang‐Kun Dai, Naixia Ren, Chang-Mei Liu, Fengtang Yang · 2026 · Cellular & Molecular Biology Letters
Chromatin context-dependent deacetylation by the asymmetric Rpd3L
Hongyun Zhao, Huadong Li, Chi Wang, Xuechen Yang, He Li, Binqian Zou, Shuqi Dong, Nan Zhang, Yuxing Zhou, Li Yi et al. · 2026 · Nucleic Acids Research
Epigenetic gene regulation and stem cell function
Aissa Benyoucef, Marjorie Brand · 2015 · Elsevier eBooks
Preventing phenotypic plasticity in cancer to mitigate therapy resistance
Mackenzie L. Coatham, Michael Jewer, Lynne-Marie M Postovit · 2021 · Elsevier eBooks
Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells
Alexander Calderon, Tamara Mestvirishvili, Francesco E. Boccalatte, Kelly V. Ruggles, Gregory David · 2024 · Epigenetics & Chromatin
Investigating the role of O-GlcNAc in the regulation of human Oct4
Sandra Nicole Brimble · 2014
The Nucleosome Remodelling and Deacetylation complex restricts Mediator access to enhancers to control transcription
Maria Xenophontos, Nicola Reynolds, Sarah Gharbi, Ewan R Johnstone, Jason Signolet, Robin Floyd, Meryem Ralser, Susanne Bornelöv, Sabine Dietmann, Remco Loos et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors
Shiri Kult, T. Olender, M. Osterwalder, Svetalana Markman, D. Leshkowitz, Sharon Krief, R. Blecher-Gonen, S. Ben-Moshe, Lydia Farack, Hadas Keren-Shaul et al. · 2020 · bioRxiv
RBBP4 modulates gene activity through acetylation and methylation of histone H3 lysine 27
Weipeng Mu, Noel S. Murcia, Keriayn N. Smith, Debashish U. Menon, Della Yee, Terry Magnuson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
BETter insight into PRC2-mutated T-ALL
Charles Edo de Bock, Jan Cools · 2021 · Blood
Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant haematopoiesis
David Lara‐Astiaso, Ainhoa Goñi‐Salaverri, Julen Mendieta-Esteban, Nisha Narayan, C Del Valle, T Gross, George Giotopoulos, Mar Navarro-Alonso, Jon Zazpe, Francesco P. Marchese et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
The Epigenetic Regulation of KCNA5 in Pediatric Solid Tumors and its Role in Cancer Biology.
Katherine Elizabeth Ryland · 2015 · Deep Blue (University of Michigan)
ATP-Dependent Heterochromatin Remodeling: A Dissertation
Benjamin J. Manning · 2015 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)