Chromatin repressive complexes in stem cells, development, and cancer
Laugesen, Anne, Helin, Kristian·2014·Cell stem cell
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- An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injuryHuy Quang Le, Matthew Alexander Hill, Ines Kollak, Martina Keck, Victoria Schroeder, Johannes Wirth, Wioletta Skrońska-Wąsek, Eva Schruf, Benjamin Strobel, Heiko F. Stahl et al. · 2021 · EMBO Reports
- A high-resolution map of transcriptional repressionLiang, Z, Karen E. Brown, Thomas D. Carroll, Ben Taylor, Ferreirós Vidal, I, Brian Hendrich, David Rueda, Amanda G. Fisher, Matthias Merkenschlager · 2017 · Apollo (University of Cambridge)
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- The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identityAlexandra Santanach, Enrique Blanco, Hua Liang Jiang, Kelly R. Molloy, Miriam Sansó, John LaCava, Lluís Morey, Luciano Di Croce · 2017 · Nature Communications
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- Chromatin Regulators in Pancreas Development and DiabetesStephanie A. Campbell, Brad G. Hoffman · 2016 · Trends in Endocrinology and Metabolism
- Sperm-borne microRNA-34c regulates maternal mRNA degradation and preimplantation embryonic development in miceLong Cui, Fang Li, Lili Zhuang, Biwei Shi, Chao‐Po Lin, Yinghui Ye · 2023 · Reproductive Biology and Endocrinology
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- Epigenetic control in Kaposi sarcoma-associated herpesvirus infection and associated diseaseJacqueline Fröhlich, Adam T. Grundhoff · 2020 · Seminars in Immunopathology
- Towards a Better Vision of Retinoic Acid Signaling during Eye DevelopmentGregg Duester · 2022 · Cells
- Polycomb Group Protein-Mediated Histone Modifications during Cell DifferentiationAbdul Aziz Khan, Andrew Lee, Tae‐Young Roh · 2015 · Epigenomics
- Rational discovery of antimetastatic agents targeting the intrinsically disordered region of MBD2Min Young Kim, Insung Na, Ji Sook Kim, Seung Han Son, Sungwoo Choi, Seol Eui Lee, Ji-Hun Kim, Kiseok Jang, Gil Alterovitz, Yu Chen et al. · 2019 · Science Advances
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- Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infectionSayaka Funata, Keisuke Matsusaka, Ryota Yamanaka, Shogo Yamamoto, Atsushi Okabe, Masaki Fukuyo, Hiroyuki Aburatani, Masashi Fukayama, Atsushi Kaneda · 2017 · Oncotarget
- LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microgliaZhongyi Zhang, Xiufang Sun, Guoquan Zhao, Yingcun Ma, Guoli Zeng · 2020 · Experimental Cell Research
- LncAY controls BMI1 expression and activates BMI1/Wnt/β-catenin signaling axis in hepatocellular carcinomaMei Hua Chen, Lisheng Fu, Fan Zhang, Ying Yang, Xing Wu · 2021 · Life Sciences
- Chromatin states shaped by an epigenetic code confer regenerative potential to the mouse liverChi Zhang, Filippo Macchi, Elena Magnani, Kirsten C. Sadler · 2021 · Nature Communications
- RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T-cell-dependent antitumor immunityZhuo Zhang, Lin Luo, Chuan Xing, Yu Chen, Peng Xu, Li Mao, Ling Zeng, Chao Li, Sadashib Ghosh, Deborah Della Manna et al. · 2021 · Nature Cancer
- MTA1 expression in human cancers – Clinical and pharmacological significanceVijaya Lakshmi Malisetty, Vasudevarao Penugurti, Prashanth Panta, Suresh Kumar Chitta, Bramanandam Manavathi · 2017 · Biomedicine & Pharmacotherapy
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- PRC2 represses transcribed genes on the imprinted inactive X chromosome in miceEmily T. Maclary, Michael Hinten, Clair E. Harris, Shriya Sethuraman, Srimonta Gayen, Sundeep Kalantry · 2017 · Genome biology
- An Essential Role of Maspin in Embryogenesis and Tumor SuppressionSijana H. Dzinic, M. Margarida Bernardo, Xiaohua Li, Rodrigo Fernandez‐Valdivia, Ye-Shih Ho, Qing‐Sheng Mi, Subhayu Bandyopadhyay, Fulvio Lonardo, Semir Vranić, Daniel S.M. Oliveira et al. · 2016 · Cancer Research
- HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroidsAlexis Gonneaud, Naomie Turgeon, Christine M. Jones, Cassandra Couture, Dominique Lévesque, François‐Michel Boisvert, François Boudreau, Claude Asselin · 2019 · Scientific Reports
- Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stressKatherine Elizabeth Ryland, Laurie Kathleen Svoboda, Eileen D. Vesely, Jeremy C. McIntyre, L Zhang, Jeffrey R. Martens, Elizabeth R. Lawlor · 2014 · Oncogene
- A positive role for polycomb in transcriptional regulation via H4K20me1Xiangdong Lv, Zhijun Han, Hao Chen, Bo Yang, Xiaofeng Yang, Yuanxin Xia, Chenyu Pan, Lin Fu, Shuo Zhang, Hui Ling Han et al. · 2016 · Cell Research
- Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2Ryan Wellington Logan, Angela Renee Ozburn, Rachel N. Arey, Kyle D. Ketchesin, Alicia Winquist, Andrew Crain, Brian T. D. Tobe, Darius D. Becker‐Krail, Matthew B. Jarpe, Xiangning Xue et al. · 2020 · Molecular Psychiatry
- Druggable Biochemical Pathways and Potential Therapeutic Alternatives to Target Leukemic Stem Cells and Eliminate the Residual Disease in Chronic Myeloid LeukemiaFabien Muselli, Jean‐François Peyron, Didier Mary · 2019 · International Journal of Molecular Sciences
- Technologies of targeting histone deacetylase in drug discovery: Current progress and emerging prospectsJinxiao Ru, Yuxi Wang, Zijia Li, Jiaxing Wang, Changyu Ren, Jifa Zhang · 2023 · European Journal of Medicinal Chemistry
- Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppressionTakeshi Ueda, Yuichiro Nakata, Akiko Nagamachi, Norimasa Yamasaki, Akinori Kanai, Yasuyuki Sera, Masato Sasaki, Hirotaka Matsui, Zen‐ichiro Honda, Hideaki Oda et al. · 2016 · Proceedings of the National Academy of Sciences
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- Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigrationShashank Gandhi, Erica J. Hutchins, Krystyna Maruszko, Jong H Park, Matthew Thomson, Marianne E. Bronner-Fraser · 2020 · eLife
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- Distinct Roles for Intestinal Epithelial Cell‐Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal HomeostasisAlexis Gonneaud, Naomie Turgeon, François Boudreau, Nathalie Perreault, Nathalie Rivard, Claude Asselin · 2015 · Journal of Cellular Physiology
- Mutations and deletions of PRC2 in prostate cancerPayal Jain, Luciano Di Croce · 2016 · BioEssays
- Construction of a prognostic model with histone modification-related genes and identification of potential drugs in pancreatic cancerYuan Chen, Ruiyuan Xu, Rexiati Ruze, Jinshou Yang, Huanyu Wang, Jianlu Song, Lei You, Chengcheng Wang, Yupei Zhao · 2021 · Cancer Cell International
- CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotencyDawei Huo, Zhaowei Yu, Rui Li, Meihan Gong, Simone Sidoli, Xukun Lu, Yuying Hou, Zhongye Dai, Yu Kong, Guifen Liu et al. · 2022 · Molecular Cell
- The mTOR chromatin-bound interactome in prostate cancerCatherine R. Dufour, Charlotte Scholtes, Ming Yan, Yonghong Chen, Lingwei Han, Ting Li, Hui Xia, Qiyun Deng, Mathieu Vernier, Vincent Giguère · 2022 · Cell Reports
- JARID2 coordinates with the NuRD complex to facilitate breast tumorigenesis through response to adipocyte‐derived leptinWei Liu, Yi Zeng, Xinhui Hao, Xin Wang, Jiaxiang Liu, Tianyang Gao, Mengdi Wang, Jingyao Zhang, Miaomiao Huo, Ting Hu et al. · 2023 · 癌症:英文版
- Promoter Methylation Analysis Reveals That KCNA5 Ion Channel Silencing Supports Ewing Sarcoma Cell ProliferationKatherine Elizabeth Ryland, Allegra G. Hawkins, Daniel J. Weisenberger, Vasu Punj, Scott C. Borinstein, Peter W. Laird, Jeffrey R. Martens, Elizabeth R. Lawlor · 2015 · Molecular Cancer Research
- Drosophila DNA-Binding Proteins in Polycomb RepressionMaksim Erokhin, Pavel G Georgiev, Darya Chetverina · 2018 · Epigenomes
- Histone modification landscape and the key significance of H3K27me3 in myocardial ischaemia/reperfusion injuryLe Ni, Bowen Lin, Yanping Zhang, Lingjie Hu, Jianghua Lin, Fengmei Fu, Meiting Shen, Can Li, Lei Chen, Jian Ping Yang et al. · 2023 · Science China Life Sciences
- Role of Retinoic Acid Signaling, FGF Signaling and Meis Genes in Control of Limb DevelopmentMarie Berenguer, Gregg Duester · 2021 · Biomolecules
- REST represses a subset of the pancreatic endocrine differentiation programDavid W. Martin, Y. Kim, Dror Sever, C. Mao, Jacques-Antoine Haefiiger, A. Grapin-Botton · 2015 · Developmental Biology
- Persistent Requirement and Alteration of the Key Targets of PRDM1 During Primordial Germ Cell Development in Mice1Chika Yamashiro, Takayuki Hirota, Kazuki Kurimoto, Tomonori Nakamura, Yukihiro Yabuta, So I Nagaoka, Hiroshi Ohta, Takuya Yamamoto, Mitinori Saitou · 2016 · Biology of Reproduction
- The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genesIsabel Adrados, Javier Larrasa-Alonso, Antonio Galarreta, Irene López‐Antona, Camino Menéndez, María Abad, Jesús Gil, Gema Moreno‐Bueno, Ignacio Palmero · 2015 · Oncogene
- Chromatin de-condensation by switching substrate elasticityMorgane Rabineau, Florence Flick, Claire Ehlinger, Éric Mathieu, Isabelle Duluc, Matthieu Jung, Bernard Senger, Leyla Kocgozlu, Pierre Schaaf, Philippe Lavall�e et al. · 2018 · Scientific Reports
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- The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programsAndreas Herchenröther, Stefanie Gossen, Tobias Friedrich, Alexander Reim, Nadine Daus, Felix Diegmüller, Jörg Leers, Hakimeh Moghaddas Sani, Sarah Gerstner, Leah Schwarz et al. · 2023 · Nature Communications
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- Trnp1 organizes diverse nuclear membrane‐less compartments in neural stem cellsMiriam Esgleas, Sven Falk, Ignasi Forné, Marc Thiry, Sònia Najas, Sirui Zhang, Aina Mas‐Sanchez, Arie Geerlof, Dierk Niessing, Zefeng Wang et al. · 2020 · The EMBO Journal
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- A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early EmbryogenesisChristo P. Christov, Kevin S. Dingwell, Mark J. Skehel, Helen S. Wilkes, Julian E. Sale, James C. Smith, Torsten Krude · 2018 · Cell Reports
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