The DOI matches its Crossref record.
Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
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WGS can directly uncover desired and unwanted editing events by comparing genome sequences before and after CRISPR/Cas9 editing.
“By comparing the genome sequences before and after CRISPR/Cas9 editing, WGS can directly uncover desired and unwanted editing events.”
From Off-target effects in CRISPR/Cas9 gene editing (2023) · cites this paper as Veres et al., 2014
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Off-target effects in CRISPR/Cas9 gene editing
Guo, C., Ma, X., Gao, F., & Guo, Y. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1143157 · Cited by 704
Metadata
- Authors
- Veres, A., Gosis, B. S., Ding, Q., Collins, R., Ragavendran, A., Brand, H., Erdin, S., Cowan, C. A., Talkowski, M. E., & Musunuru, K.
- Corresponding author
- Musunuru, Kiran
- ORCID
- Venue
- Cell stem cell
- Publisher
- Elsevier BV
- Published
- 2014-08
- Volume
- 15
- Issue
- 2
- Pages
- 254
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W4241813303
- Cited by
- 37
- References
- 0
- Citations by year
- 2024: 4 · 2023: 4 · 2022: 5 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 7 · 2017: 5 · 2016: 2 · 2015: 1 · 2014: 1
- FWCI
- 1.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell stem cell (publishedVersion)
- Funders
- Broad Institute
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA regulation and disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Pluripotent Stem Cells Research
- Keywords
- off-target mutagenesis, CRISPR/Cas9, TALEN, genome editing, human pluripotent stem cells, single-cell genotyping, whole genome sequencing
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