Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Wilson, Nicola K., Kent, David G., Buettner, Florian, Shehata, Mona, Macaulay, Iain C., Calero-Nieto, Fernando J., Sánchez Castillo, Manuel, Oedekoven, Caroline A. +9 more·2015·Cell Stem Cell

DOI 10.1016/j.stem.2015.04.004

Cited by (468)

Items 101–200 of 468

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Chris Sebastiaan Vink, Samanta Antonella Mariani, Elaine Anne Dzierzak · 2022 · HemaSphere
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