Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia

Zambetti, Noemi A., Ping, Zhen, Chen, Si, Kenswil, Keane J.G., Mylona, Maria A., Sanders, Mathijs A., Hoogenboezem, Remco M., Bindels, Eric M.J. +15 more·2016·Cell stem cell

Cited by (342)

Items 201–300 of 342

  1. Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies
    Yasutaka Hayashi, Koutarou Nishimura, Atsushi Tanaka, Daichi Inoue · 2023 · International Journal of Hematology
  2. Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC–Alarmin Axis
    Nicole D. Vincelette, Xiaoqing Yu, Andrew Tucker Kuykendall, Jungwon Moon, Siyuan Su, Chia‐Ho Cheng, Rinzine Sammut, Tiffany N. Razabdouski, Hai Vu Nguyen, Erika Adriana Eksioglu et al. · 2024 · Blood Cancer Discovery
  3. The evolution of leukaemia from pre‐leukaemic and leukaemic stem cells
    Liran I. Shlush, Tzah Feldman · 2021 · Journal of Internal Medicine
  4. Cell senescence and malignant transformation in the inherited bone marrow failure syndromes: Overlapping pathophysiology with therapeutic implications
    Emma M. Groarke, Rodrigo T. Calado, Johnson M. Liu · 2022 · Seminars in Hematology
  5. The role of exosomes in the stemness maintenance and progression of acute myeloid leukemia.
    Qian Li, Mengyuan Wang, Ling-Bo Liu · 2023 · Biochemical Pharmacology
  6. Hematopoietic development: a gap in our understanding of inherited bone marrow failure
    Peter Kurre · 2017 · Experimental Hematology
  7. Shwachman-Diamond Syndrome
    Kasiani C. Myers, Akiko Shimamura · 2018 · Pediatric oncology
  8. Diagnosis of Myelodysplastic Syndromes: From Immunological Observations to Clinical Applications
    Yannick Simoni, Nicolas Chapuis · 2022 · Diagnostics
  9. STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes
    Zoe King, Sudhamsh Reddy Desai, David A. Frank, Aditi Shastri · 2025 · Neoplasia
  10. Mesenchymal stem/stromal cells from a transplanted, asymptomatic patient with Fanconi anemia exhibit an aging-like phenotype and dysregulated expression of genes implicated in hematopoiesis and myelodysplasia
    Christopher L. Haga, Siddaraju V. Boregowda, Cori N. Booker, Veena Krishnappa, Jacqueline Strivelli, Enrico Cappelli, Donald G. Phinney · 2022 · Cytotherapy
  11. The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression
    Youmna Sami Kfoury, Fei Ji, Esha Jain, Michael C. Mazzola, Giulia Schiroli, Ani Papazian, François Mercier, David B. Sykes, Anna Kiem, Mark A. Randolph et al. · 2023 · Blood Advances
  12. Stem cell damage after chemotherapy- can we do better?
    Joy Tang, Nan Zhu, Sridhar Rao, Karen-Sue Carlson · 2019 · Best Practice & Research Clinical Haematology
  13. IDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome
    Stéphanie Mourad, Mélanie Bilodeau, Mathieu Roussy, Louise Laramée, Luc Boulianne, Alexandre Rouette, Loubna Jouan, Patrick Gendron, Michel Duval, Pierre Teira et al. · 2019 · Frontiers in Oncology
  14. Molecular dissection of engraftment in a xenograft model of myelodysplastic syndromes
    Mathieu Meunier, Charles Dussiau, Natacha Mauz, Anne‐Sophie Alary, Christine Lefebvre, Gautier Szymanski, Mylène Pezet, Françoise Blanquet, Olivier Kosmider, Sophie Park · 2018 · Oncotarget
  15. An inflammatory T-cell-stromal axis contributes to hematopoietic stem/progenitor cell failure and clonal evolution in human myelodysplastic syndrome
    Lanpeng Chen, Yujie Bian, Eline Pronk, Claire van Dijk, Tim V. D. van Tienhoven, Remco Michiel Hoogenboezem, Eric M. Bindels, Dennis A. Bosch, Sadaf Fazeli, Aniek O. de Graaf et al. · 2025 · Nature Communications
  16. Integrative spatial multi-omics reveal niche-specific inflammatory signaling and differentiation hierarchies in AML
    Enes Dasdemir, Ivo Veletić, Christopher P. Ly, Andres Ernesto Quesada, Christopher D. Pacheco, Fatima Zahra Jelloul, Pâmella Borges, Sreyashi Basu, Sonali Jindal, Zhiqiang Wang et al. · 2025 · iScience
  17. Canonical Wnt: a safeguard and threat for erythropoiesis
    Rosa A. Krimpenfort, Micha Nethe · 2021 · Blood Advances
  18. The bone marrow niche landscape: a journey through aging, extrinsic and intrinsic stressors in the haemopoietic milieu
    Antonio Giovanni Solimando, Assunta Melaccio, Angelo Vacca, Roberto Ria · 2022 · Journal of Cancer Metastasis and Treatment
  19. What is the role of the microenvironment in MDS?
    Laura Maria Calvi, Allison J. Li, Michael W. Becker · 2019 · Best Practice & Research Clinical Haematology
  20. FAK Deficiency in Bone Marrow Stromal Cells Alters Their Homeostasis and Drives Abnormal Proliferation and Differentiation of Haematopoietic Stem Cells
    Yuenv Wu, Lydia Campos, Élisabeth Daguenet, Zhiguo Hé, Tiphanie Picot, Emmanuelle Tavernier, Gilbert Soglu, Denis Guyotat, Carmen Mariana Aanei · 2020 · Cells
  21. The Mesenchymal Niche in Myelodysplastic Syndromes
    Chloé Friedrich, Olivier Kosmider · 2022 · Diagnostics
  22. Pediatric Bone Marrow Failure: A Broad Landscape in Need of Personalized Management
    Lotte T. W. Vissers, Mirjam van der Burg, Arjan C. Lankester, Frans J. W. Smiers, Marije Bartels, Alexander B. Mohseny · 2023 · Journal of Clinical Medicine
  23. Putative Mechanisms Underlying Cardiovascular Disease Associated with Clonal Hematopoiesis of Indeterminate Potential
    Sarah S. Burns, Reuben Kapur · 2020 · Stem Cell Reports
  24. Bone marrow mesenchymal stromal cells in chronic myelomonocytic leukaemia: overactivated WNT/β‐catenin signalling by parallel RNA sequencing and dysfunctional phenotypes
    Ruohao Xu, Xin Huang, Chao Li, Chengxin Deng, Minming Li, Ping Wu, Suxia Geng, Peilong Lai, Zesheng Lu, Jianyu Weng et al. · 2021 · British Journal of Haematology
  25. A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
    Ioanna Mosialou, Abdullah Mahmood Ali, Rossella Labella, Brygida C. Bisikirska, Álvaro Cuesta‐Domínguez, Paraskevi Vgenopoulou, Ismarc Reyes, Sanjana M. Rao, Anqi Wang, Na Luo et al. · 2025 · Cancer Cell
  26. An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment
    Cristian Sandoval, Yolanda Calle, Karina Godoy, Jorge G. Farías · 2023 · International Journal of Molecular Sciences
  27. Inducible Sbds deletion impairs bone marrow niche capacity to engraft donor bone marrow after transplantation
    Ji Zha, Lori Kunselman, Hongbo Michael Xie, Brian Ennis, Yash Shah, Xia Qin, Jian‐Meng Fan, Daria V. Babushok, Timothy S. Olson · 2021 · Blood Advances
  28. The mechanisms of mutual relationship between malignant hematologic cells and mesenchymal stem cells: Does it contradict the nursing role of mesenchymal stem cells?
    Alireza Goodarzi, Mohsen Valikhani, Fatemeh Amiri, Armita Safari · 2022 · Cell Communication and Signaling
  29. Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation
    Jin Ye, Isabel A. Calvo, Itziar Cenzano, Amaia Vilas‐Zornoza, Xabier Martinez‐de‐Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C. Viñado, Patxi San Martín‐Úriz et al. · 2022 · iScience
  30. Innate immune-inflammatory signaling milieu in myeloid leukemia and aging-associated clonal hematopoiesis pathologies
    Satyaki Bhowmik, Anwesha Bose, Amitava Sengupta · 2025 · Frontiers in Immunology
  31. Pathophysiology of Myelodysplastic Syndromes
    Michaëla Fontenay, Batoul Farhat, Ismaël Boussaid · 2021 · Hemato
  32. The bone marrow microenvironment—driver of leukemia evolution?
    Mayra García, Ching‐Cheng Chen · 2017 · Stem Cell Investigation
  33. The origin of leukemia: Genetic alterations and inflammatory factors in the development of premalignant clonal hematopoiesis
    Daniel Sjövall, Anna Staffas · 2020 · Seminars in Hematology
  34. Inflammation in Myeloid Malignancies: From Bench to Bedside
    Eli M. Soyfer, Angela G. Fleischman · 2021 · Journal of Immunotherapy and Precision Oncology
  35. Critical role of niche S100A8 for acute myeloid leukemia progression and hematopoiesis regeneration
    Fuling Zhou, Xiaoyan Liu, Jinxian Wu, Xinqi Li, Ruiyang Pan, Li Liu, Tingting Huang, Linlu Ma, Guopeng Chen, Qian Wang et al. · 2025 · Blood Advances
  36. Instructive interaction between myelodysplastic hematopoiesis and the bone marrow microenvironment at the single-cell level
    Johann-Christoph Jann, Nanni Schmitt, Alexander Streuer, Qingyu Xu, Vladimir Riabov, Eva Altrock, Nadine Weimer, Verena Nowak, Julia Obländer, Iris Palme et al. · 2024 · Blood Neoplasia
  37. Towards deciphering the bone marrow microenvironment with spatial multi-omics
    Raymond K. H. Yip, Edwin D. Hawkins, Rory J. Bowden, Kelly L. Rogers · 2025 · Seminars in Cell and Developmental Biology
  38. Inflammatory pathways and the bone marrow microenvironment in inherited bone marrow failure syndromes
    Nicholas Neoman, Hye Na Kim, Jacob Viduya, Anju Goyal, Y. Lucy Liu, Kathleen M. Sakamoto · 2025 · Stem Cells
  39. Mitochondrial Effects on Seeds of Cancer Survival in Leukemia
    Hend E. El-Shaqanqery, Rania Hassan Mohamed, Ahmed A. Sayed · 2021 · Frontiers in Oncology
  40. Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans
    Long Zhe Guo, Smrithi Salian, Jingyi Xue, Nicola Rath, Justine Rousseau, Hyunyun Kim, Sophie Ehresmann, Shahida Moosa, Norio Nakagawa, Hiroshi Kuroda et al. · 2023 · The American Journal of Human Genetics
  41. Clonal hematopoiesis of indeterminate potential: the root cause of, and fertile ground for, hematological malignancies
    Qiqi Zhuang, Shengjie Jin, Wei Wang, Yan Wang, Hongyan Tong, Zuyun Liu, Jie Sun · 2024 · Trends in Molecular Medicine
  42. Ribosome specialization by cancer-associated ribosomal protein mutations: progress made and open questions
    Marino Caruso, Kim De Keersmaecker · 2025 · Philosophical Transactions of the Royal Society B Biological Sciences
  43. The Bone Marrow Niche – The Tumor Microenvironment That Ensures Leukemia Progression
    Bruno A. Cardoso · 2020 · Advances in experimental medicine and biology
  44. Mesenchymal Stromal Cells as a Cellular Target in Myeloid Malignancy: Chances and Challenges in the Genome Editing of Stromal Alterations
    Bella Banjanin, Rebekka K. Schneider · 2021 · Frontiers in Genome Editing
  45. When should transplant physicians think about familial blood cancers?
    Amy M. Trottier, Sarah A. Bannon, Qaiser Bashir, Hetty E. Carraway, Inga Hofmann, Lucy A. Godley · 2019 · Advances in Cell and Gene Therapy
  46. Phenotype of mesenchymal stem cells from patients with myelodyplastic syndrome maybe partly modulated by decitabine
    Yanbin Pang, Suxia Geng, Hongyang Zhang, Peilong Lai, Pengjun Liao, Lingji Zeng, Zesheng Lu, Jianyu Weng, Xin Du · 2019 · Oncology Letters
  47. Inflamm-aging of hematopoietic stem cells
    Zhiyang Chen, Zhenyu Ju · 2019 · Blood Science
  48. Marrow Microenvironmental Pathobiology and Therapeutic Opportunities for TP53-Mutated Myelodysplastic Syndrome/Acute Myeloid Leukemia
    Cameron J. Hunter, Annie Im, Rory Michael Shallis · 2026 · Cancers
  49. Myelodysplastic syndrome progress to acute myeloid leukemia: new insights and updates
    Yucheng Zhang, Lixiang Yan, Chenyang Fan, Bofan Zhao, Meng Chen, Xiaogang Hao, Gengda Zhu, Yanan Jia, Yan Xu, Zhexin Shi · 2026 · Frontiers in Immunology
  50. SOHO State of the Art Updates and Next Questions: An Update on Higher Risk Myelodysplastic Syndromes
    Michael Jamie Hochman, Amy Elizabeth Dezern · 2024 · Clinical Lymphoma Myeloma & Leukemia
  51. Ultralow-dose irradiation enables engraftment and intravital tracking of disease initiating niches in clonal hematopoiesis
    Kevin Lee, Wimeth M. Dissanayake, Melissa MacLiesh, Cih-Li Hong, Zi Yin, Yuko Kawano, Christina M. Kaszuba, Hiroki Kawano, Emily R. Quarato, Brian Marples et al. · 2024 · Scientific Reports
  52. Bone marrow niches in myelodysplastic syndromes
    Giovanna Tosato, Jingxin Feng, Hidetaka Ohnuki, Minji Sim · 2021 · Journal of Cancer Metastasis and Treatment
  53. Comparison of Laboratory Methods for the Clinical Follow Up of Checkpoint Blockade Therapies in Leukemia: Current Status and Challenges Ahead
    Başak Aru, Mojdeh Soltani, Cemil Pehlivanoğlu, Ege Gürlü, Mazdak Ganjalıkhani-Hakemi, Gülderen Yanıkkaya Demirel · 2022 · Frontiers in Oncology
  54. Insights Regarding the Role of Inflammasomes in Leukemia: What Do We Know?
    Fabíola Silva Alves-Hanna, Juniel Assis Crespo-Neto, Glenda Menezes Nogueira, Daniele Sá Pereira, Amanda Barros Lima, Thaís Lohana Pereira-Ribeiro, Vitória Giovanna Rodrigues Santos, Joey Ramone Ferreira Fonseca, Fábio Magalhães-Gama, Aya Sadahiro et al. · 2023 · Journal of Immunology Research
  55. BONE MARROW MICROENVIRONMENT INVOLVEMENT IN T-MN: FOCUS ON MESENCHYMAL STEM CELLS
    Maria Teresa Voso, Giulia Falconi, Emiliano Fabiani · 2023 · Mediterranean Journal of Hematology and Infectious Diseases
  56. Multi-Walled Carbon Nanotubes Accelerate Leukaemia Development in a Mouse Model
    Qingqing Wang, Jingdan Han, Mujia Wei, Huikai Miao, Min Zhang, Biao Wu, Yao Chen, Yanwen Zheng, Robert Peter Gale, Bin Yin · 2024 · Toxics
  57. Paracrine regulation of normal and malignant hematopoiesis
    Wanxing Chai‐Ho, John P. Chute · 2017 · Current Opinion in Hematology
  58. The role of innate immunity in MDS pathogenesis
    David Andrew Sallman, Alan F. List · 2019 · HemaSphere
  59. A compartmentalized inflammatory landscape and macrophage plasticity regulate Tet2 +/− -mediated clonal hematopoiesis
    Kevin Lee, Cih-Li Hong, Wimeth M. Dissanayake, Gulzada Kulzhanova, Alexander Noel Pfeffer, Haiyin Li, Senthil Sivakumar, Zi Yin, Emily R. Quarato, Lauren Benoodt et al. · 2026 · Blood
  60. IDH2 mutation accelerates TPO‐induced myelofibrosis with enhanced S100a8/a9 and NFκB signaling in vivo
    Chien‐Chin Lin, Chi‐Yuan Yao, Yu‐Hung Wang, Yueh-Chwen Hsu, Chang‐Tsu Yuan, Tsung‐Chih Chen, Chia‐Lang Hsu, Sze‐Hwei Lee, Jhih‐Yi Lee, Pin‐Tsen Shih et al. · 2024 · eJHaem
  61. Current Understanding of Myelomatous Mesenchymal Stromal Cells Extended through Advances in Experimental Methods
    Michiko Ichii, Naoki Hosen · 2020 · Cancers
  62. The mesenchymal compartment in myelodysplastic syndrome: Its role in the pathogenesis of the disorder and its therapeutic targeting
    Charalampos G. Pontikoglou, Angelos Matheakakis, Helen Α. Papadaki · 2023 · Frontiers in Oncology
  63. Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms
    Angelo Jose Guilatco, Mithun Vinod Shah, Megan Moore Weivoda · 2024 · Journal of bone oncology
  64. Cellular and immunotherapies for myelodysplastic syndromes
    Ryan J. Stubbins, Hannah Marie Cherniawsky, Aly Karsan · 2024 · Seminars in Hematology
  65. Autophagy Driven Extracellular Vesicles in the Leukaemic Microenvironment
    Rebecca H. Horton, Tom Wileman, Stuart A. Rushworth · 2020 · Current Cancer Drug Targets
  66. The Bone’s Role in Myeloid Neoplasia
    Lukas Kazianka, Philipp Bernhard Staber · 2020 · International Journal of Molecular Sciences
  67. Mutation-Driven S100A8 Overexpression Confers Aberrant Phenotypes in Type 1 CALR-Mutated MPN
    Ying‐Hsuan Wang, Ying‐Ju Chen, Yi‐Hua Lai, Ming‐Chung Wang, Yi‐Yang Chen, Yuying Wu, Yao-Ren Yang, Hsing-Yi Tsou, Chian-Pei Li, Chia‐Chen Hsu et al. · 2023 · International Journal of Molecular Sciences
  68. Bone Marrow Stromal Niche: A New Master Regulator of Hematological Myeloid Malignancies
    Paraskevi Vgenopoulou, Stavroula Kousteni · 2020 · Elsevier eBooks
  69. The Link between Modifiable Risk Factors and Myeloid Disorders—From Plate to Pathogenesis
    Joshua T. Weinreb, Omar Ibrahim Abdel-Wahab, Urvi Ashok Shah · 2025 · Blood Cancer Discovery
  70. Targeting the NLRP3 inflammasome signalling in acute myeloid leukemia: Mechanisms, therapeutics, and future directions
    Sally H. Fayad, Alaa Mohamed Salah, Ayad A. Jaffa, Nadine Darwiche · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  71. Response of the Bone Marrow Stem Cells and the Microenvironment to Stress
    Duygu Uçkan, Bihter Muratoğlu · 2022 · Springer eBooks
  72. Resource: A Cellular Developmental Taxonomy of the Bone Marrow Mesenchymal Stem Cell Population in Mice
    Paola Pisterzi, Lanpeng Chen, Claire van Dijk, Michiel J. W. Wevers, Eric Bindels, Marc H.G.P. Raaijmakers · 2023 · HemaSphere
  73. In Vitro Insights Into the Influence of Marrow Mesodermal/Mesenchymal Progenitor Cells on Acute Myelogenous Leukemia and Myelodysplastic Syndromes
    Jane L. Liesveld, Jaques Galipeau · 2023 · Stem Cells
  74. When inflammatory stressors dramatically change, disease phenotypes may transform between autoimmune hematopoietic failure and myeloid neoplasms
    Xi-Chen Zhao, Bo Ju, Nuan-Nuan Xiu, Xiao-Yun Sun, Fanjun Meng · 2024 · Frontiers in Immunology
  75. The immunoregulatory role of monocytes and thrombomodulin in myelodysplastic neoplasms
    Luca L. G. Janssen, Nathalie van Leeuwen-Kerkhoff, Theresia M. Westers, Tanja D. de Gruijl, Arjan A. van de Loosdrecht · 2024 · Frontiers in Oncology
  76. Preclinical efficacy of tasquinimod in myelodysplastic neoplasms: Restoring erythropoiesis and mitigating bone loss
    Manja Wobus, Heike Weidner, Rebekka Wehner, Anna-Lena Baumann, Kristin Möbus, Ekaterina Balaian, Marie Törngren, Erik Vahtola, Helena Eriksson, Susann Winter et al. · 2026 · HemaSphere
  77. Tuning of the Hematopoietic Stem Cell Compartment in its Inflammatory Environment
    Vinothini Govindarajah, Damien Reynaud · 2018 · Current Stem Cell Reports
  78. Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of RUNX1-FPD
    Martijn P. T. Ernst, Eline Pronk, Claire van Dijk, Paulina M. H. van Strien, Tim V. D. van Tienhoven, Michiel J. W. Wevers, Mathijs Arnoud Sanders, Eric M. Bindels, Nancy A. Speck, Marc H.G.P. Raaijmakers · 2023 · HemaSphere
  79. Cytotoxic Therapy–Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms
    Angela Stoddart, Jianghong Wang, Anthony A. Fernald, Elizabeth M. Davis, Camille R. Johnson, Chun‐Mei Hu, Jason Xiaojun Cheng, Megan E. McNerney, Michelle M. Le Beau · 2020 · Blood Cancer Discovery
  80. Targeting the leukemic bone marrow microenvironment
    Eva Kristin von der Heide, Martín Neumann, Claudia Dorothea Baldus · 2017 · Oncotarget
  81. ASC specks: a biomarker for myelodysplastic syndromes?
    Dominik Georg Friedrich Wolf, Eicke Latz · 2018 · The Lancet Haematology
  82. Myelodysplastic syndromes disable support of human hematopoietic stem and progenitor cells by CD271, VCAM- 1 and CD146 expressing marrow niche cells
    Yuko Kawano, Hiroki Kawano, Dalia H. Ghoneim, Thomas J. Fountaine, Daniel K. Byun, Mark W. LaMere, Jason Harold Mendler, Tzu‐Chieh Ho, Noah Salama, Benjamin J. Frisch et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  83. Chromosomal abnormalities of mesenchymal stromal cells in hematological malignancies
    Mateus de Oliveira Lisboa, Tamara Borgonovo, Letícia Fracaro, Aline Rangel Pozzo, Paulo Roberto Slud Brofman, Sabine Mai · 2025 · Oncogene
  84. Induced pluripotent stem cell-based modelling of disease evolution in myeloid leukemia: MDS to AML
    Jacqueline Boultwood · 2025 · Advances in Biological Regulation
  85. MDM4 haploinsufficiency leads to p53-mediated bone marrow failure
    Richa Sharma, Senthil Velan Bhoopalan, Robert Meyer, Lei Han, Swarna Beesetti, Nana Liu, Priyanka Singh, lance Palmer, Baranda S. Hansen, Majd Khiami et al. · 2026 · Blood
  86. Functional impact of the eIF6 N106S mutation on ribosome biogenesis in wild type and Shwachman–Diamond syndrome cells
    Alexis Bertrand, Sarah Le Page, Vithura Pirabakaran, Laëtitia Kermasson, Erika Brunet, Jean Donadieu, Pierre‐Emmanuel Gleizes, Marie-Françoise O’Donohue, Patrick Revy · 2026 · Molecular Medicine
  87. Under Pressure: When a Transformed Environment Pushes Cells to Malignancy
    María García-Fernández, Simón Méndez‐Ferrer · 2016 · Cell stem cell
  88. Genetics in Hematologic Disorders: Implications of Recurring Chromosome Abnormalities and Gene Mutations
    Yanming Zhang · 2018 · Springer eBooks
  89. Osteoblast biology: developmental origin and interactive nature of osteoblasts
    Bram C. J. van der Eerden, André J. van Wijnen · 2020 · Elsevier eBooks
  90. Physiopathologie des syndromes myélodysplasiques
    Michaëla Fontenay, Ismaël Boussaid, Nicolas Chapuis · 2023 · Bulletin du Cancer
  91. Influences on the Hematopoietic Stem Cell Niche
    Brian M Barth · 2024
  92. Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis
    Valentine Marchand, Lucie Laplane, L. Valensi, Isabelle Plo, Marine Aglave, Aymeric Silvin, Florence Pasquier, Françoise Porteu, William Vainchenker, Dorothée Selimoglu‐Buet et al. · 2024 · iScience
  93. Reactive oxygen species (ROS) on Ribosome: from damage to regulation
    Emir Behluli, Shefki Xharra, Hilada Nefić, Rifat Hadžiselimović, Gazmend Temaj · 2025 · Current Issues in Pharmacy and Medical Sciences
  94. Indicators of an increased risk of therapy-related myeloid neoplasms in lymphoma patients: how can we best evaluate severe impairment of bone marrow function?
    Tadeusz Kubicki, Anna Ewa Pula, Aleksandra Gołoś, Łukasz Bołkuń, Bartosz Puła · 2025 · Expert Review of Hematology
  95. Serum Inflamma-miR Signature: A Biomarker of Myelodysplastic Syndrome?
    Marianna Mariani, Domenico Mattiucci, Elisa Rossi, Valeria Mari, Erico Masala, Angelica Giuliani, Valeria Santini, Fabiola Olivieri, Elena Marinelli Busilacchi, Stefania Mancini et al. · 2020 · Frontiers in Oncology
  96. Response of the Bone Marrow Stem Cells and the Microenvironment to Stress
    Duygu Uçkan, Bihter Muratoğlu · 2022 · Springer eBooks
  97. A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia demonstrates cancer-crosstalk with stroma to impair normal tissue function
    Ninib Baryawno, Dariusz Przybylski, Monika S. Kowalczyk, Youmna Sami Kfoury, Nicolas Sévère, Karin U. Gustafsson, Mercier Francois, Marcin Tabaka, Matan Hofree, Danielle Ashley Dionne et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Mesenchymal stem cell-derived S100A8 facilitates leukemia stem cell maintenance via TLR4/PI3K/Akt signaling
    Fuling Zhou, Xiaoyan Liu, Jinxian Wu, Xinqi Li, Ruiyang Pan, Li Liu, Tingting Huang, Linlu Ma, Guopeng Chen, Qian Wang et al. · 2024 · Research Square
  99. Ecological determinants of disease and immunity in myelodysplastic syndromes
    Robert F. Stanley, Beatrice D. Zhang, Kimon V. Argyropoulos, P Zhang, Maxim I. Maron, Brianna Gipson, C. Y. Park, Kenyon Weis, Alexander M. Lewis, Zoe Katsamakis et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Chronic Myelomonocytic Leukemia (CMML)
    Matthieu Duchmann, Nolwenn Lucas, Raphaël Itzykson, Éric Solary · 2018 · Hematologic malignancies