Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons

van der Kant, Rik, Langness, Vanessa F., Herrera, Cheryl M., Williams, Daniel A., Fong, Lauren K., Leestemaker, Yves, Steenvoorden, Evelyne, Rynearson, Kevin D. +7 more·2019·Cell Stem Cell
DOI 10.1016/j.stem.2018.12.013

Cited by (353)

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  19. Additional file 3 of Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
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  20. Additional file 5 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
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  21. Additional file 6 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
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  22. Additional file 4 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
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  23. Additional file 1 of Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
    Michal Nemergut, Sérgio M. Marques, Lukáš Uhrík, Tereza Váňová, Markéta Nezvedová, Darshak Chandulal Gadara, Durga Jha, Jan Tulis, Veronika Novakova, Joan Planas-Iglesias et al. · 2023 · Figshare
  24. Additional file 10 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  25. Additional file 8 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  26. Additional file 3 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
    Eugen Semikasev, Barbara Ahlemeyer, Till Acker, Anne Schänzer, Eveline Baumgart‐Vogt · 2024 · Figshare
  27. Additional file 11 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
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  29. Additional file 7 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  30. Additional file 1 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
    Eugen Semikasev, Barbara Ahlemeyer, Till Acker, Anne Schänzer, Eveline Baumgart‐Vogt · 2024 · Figshare
  31. Additional file 7 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
    Eugen Semikasev, Barbara Ahlemeyer, Till Acker, Anne Schänzer, Eveline Baumgart‐Vogt · 2024 · Figshare
  32. Additional file 4 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
    Eugen Semikasev, Barbara Ahlemeyer, Till Acker, Anne Schänzer, Eveline Baumgart‐Vogt · 2024 · Figshare
  33. Additional file 9 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  34. Additional file 3 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  35. Additional file 2 of Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
    Eugen Semikasev, Barbara Ahlemeyer, Till Acker, Anne Schänzer, Eveline Baumgart‐Vogt · 2024 · Figshare
  36. Additional file 2 of Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
    Michal Nemergut, Sérgio M. Marques, Lukáš Uhrík, Tereza Váňová, Markéta Nezvedová, Darshak Chandulal Gadara, Durga Jha, Jan Tulis, Veronika Novakova, Joan Planas-Iglesias et al. · 2023 · Figshare
  37. Additional file 1 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  38. Additional file 5 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
  39. Additional file 2 of Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology
    Choe, Mu Seog, Yeo, Han Cheol, Kim, Joong Sun, Jean Lee, Hae Jun Lee, Kim, Hyung-Ryong, Kyung Min Baek, Jung, Na-Yeon, Murim Choi, Lee, Min Young · 2024 · Figshare
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