Principles of signaling pathway modulation for enhancing human naive pluripotency induction

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Derivation of Human Trophoblast Stem Cells

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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

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The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

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SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

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Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

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Deterministic direct reprogramming of somatic cells to pluripotency

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Molecular Criteria for Defining the Naive Human Pluripotent State

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Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

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Interspecies Chimerism with Mammalian Pluripotent Stem Cells

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Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

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Single-cell transcriptomic characterization of a gastrulating human embryo

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Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

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Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

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The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

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Regulatory Principles of Pluripotency: From the Ground State Up

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Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast

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Hallmarks of pluripotency

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Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

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The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency

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Defining an essential transcription factor program for naïve pluripotency

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Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

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Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

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Chromatin analysis in human early development reveals epigenetic transition during ZGA

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Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3

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Metastable Pluripotent States in NOD-Mouse-Derived ESCs

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Epigenetic resetting of human pluripotency

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The Transcriptional and Functional Properties of Mouse Epiblast Stem Cells Resemble the Anterior Primitive Streak

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Establishment of mouse expanded potential stem cells

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Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

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Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory

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Induction of Pluripotency in Adult Unipotent Germline Stem Cells

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Dynamic binding of RBPJ is determined by Notch signaling statusPreprint

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Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation

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An alternative pluripotent state confers interspecies chimaeric competency

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Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

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Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

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Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor-κB via c-SRC– and Oxidant-Dependent Cell Death

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Derivation of ground-state female ES cells maintaining gamete-derived DNA methylation

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TFAP2C regulates transcription in human naive pluripotency by opening enhancers

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Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States

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Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm

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Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

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Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal

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A Call to Standardize Teratoma Assays Used to Define Human Pluripotent Cell Lines

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Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3

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Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation

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Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency

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Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency

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Stem Cells: A Renaissance in Human Biology Research

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The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells

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Cell competition constitutes a barrier for interspecies chimerism

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Large-Scale Analysis of Loss of Imprinting in Human Pluripotent Stem Cells

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Src Tyrosine Kinases Mediate Activations of NF-κB and Integrin Signal during Lipopolysaccharide-Induced Acute Lung Injury

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Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality

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Safeguards for Cell Cooperation in Mouse Embryogenesis Shown by Genome-Wide Cheater Screen

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Notch inhibition allows oncogene-independent generation of iPS cells

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Global Characterization of X Chromosome Inactivation in Human Pluripotent Stem Cells

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Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ

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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

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Structural Basis for the SOX-Dependent Genomic Redistribution of OCT4 in Stem Cell Differentiation

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Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation

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