The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
Damage control: cellular mechanisms of plasma membrane repair
Open accessAbstract
Summary When wounded, eukaryotic cells reseal in a few seconds. Ca2+ influx induces exocytosis of lysosomes, a process previously thought to promote repair by “patching” wounds. New evidence suggests that resealing involves direct wound removal. Exocytosis of lysosomal acid sphingomyelinase triggers endocytosis of lesions, followed by intracellular degradation. Characterization of injury-induced endosomes revealed a role for caveolae, sphingolipid-enriched plasma membrane invaginations that internalize toxin pores and are abundant in mechanically stressed cells. These findings provide a novel mechanistic explanation for the muscle pathology associated with mutations in caveolar proteins. Membrane remodeling by the ESCRT complex was also recently shown to participate in small wound repair, emphasizing that cell resealing involves previously unrecognized mechanisms for lesion removal, which are distinct from the “patch” model.
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Cites
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Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
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The multiple faces of caveolae
Parton, R. G., & Simons, K. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2122 · Cited by 1,454
Plasma Membrane Repair Is Mediated by Ca2+-Regulated Exocytosis of Lysosomes
Reddy, A., Caler, E. V., & Andrews, N. W. (2001) · Cell · doi:10.1016/s0092-8674(01)00421-4 · Cited by 1,042
Self-citationCells Respond to Mechanical Stress by Rapid Disassembly of Caveolae
Sinha, B., Köster, D., Ruez, R., Gonnord, P., Bastiani, M., Abankwa, D., Stan, R. V., Butler-Browne, G., Vedie, B., Johannes, L., et al. (2011) · Cell · doi:10.1016/j.cell.2010.12.031 · Cited by 969
Caveolae as plasma membrane sensors, protectors and organizers
Parton, R. G., & del Pozo, M. A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3512 · Cited by 924
Role of Caveolae and Caveolins in Health and Disease
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Regulated internalization of caveolae.
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Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells
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Maas, S. L. N., Breakefield, X. O., & Weaver, A. M. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2016.11.003 · Cited by 1,429
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Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts
Stewart, M. P., Langer, R., & Jensen, K. F. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00678 · Cited by 747
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
Gong, Y.-N., Guy, C., Olauson, H., Becker, J. U., Yang, M., Fitzgerald, P., Linkermann, A., & Green, D. R. (2017) · Cell · doi:10.1016/j.cell.2017.03.020 · Cited by 689
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Metadata
- Authors
- Andrews, N. W., Almeida, P. E., & Corrotte, M.
- Venue
- Trends in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 24
- Issue
- 12
- Pages
- 734-742
- ISSN
- 0962-8924 (ISSN-L)
- OpenAlex
- W2027407745
- Cited by
- 340
- References
- 77
- FWCI
- 1.76
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
