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Cited by 665

The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.

Tight Junction Structure and Function Revisited

Otani, Tetsuhisa, Furuse, Mikio·2020·Trends in Cell Biology
DOI 10.1016/j.tcb.2020.08.004
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Abstract

Tight junctions (TJs) are intercellular junctions critical for building the epithelial barrier and maintaining epithelial polarity. The claudin family of membrane proteins play central roles in TJ structure and function. However, recent findings have uncovered claudin-independent aspects of TJ structure and function, and additional players including junctional adhesion molecules (JAMs), membrane lipids, phase separation of the zonula occludens (ZO) family of scaffolding proteins, and mechanical force have been shown to play important roles in TJ structure and function. In this review, we discuss how these new findings have the potential to transform our understanding of TJ structure and function, and how the intricate network of TJ proteins and membrane lipids dynamically interact to drive TJ assembly.

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Metadata

Authors
Otani, T., & Furuse, M.
Venue
Trends in Cell Biology
Publisher
Elsevier BV
Published
2020-10
Volume
30
Issue
10
Pages
805-817
ISSN
0962-8924 (ISSN-L)
DOI
10.1016/j.tcb.2020.08.004
OpenAlex
W3082443534
Cited by
665
References
120
FWCI
8.72
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Tight Junction Structure and Function Revisited. https://app.cochat.ai/papers/10.1016/j.tcb.2020.08.004
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Otani, T., & Furuse, M. (2020). Tight Junction Structure and Function Revisited. Trends in Cell Biology. https://doi.org/10.1016/j.tcb.2020.08.004

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.