Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21
Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A.·2015·Trends in Endocrinology & Metabolism
Cited by (286)
Items 101–200 of 286
- Metabolic roles of endocrine fibroblast growth factorsIsabel Fernandes-Freitas, Bryn M. Owen · 2015 · Current Opinion in Pharmacology
- Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic SignalsAlejandra Freire‐Regatillo, Pilar Argente-Arizón, Jesús Argente, Luis Miguel García‐Segura, Julie Ann Chowen · 2017 · Frontiers in Endocrinology
- Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on studyKosuke Robert Shima, Tsuguhito Ota, Kenichiro Kato, Yumie Takeshita, Hirofumi Misu, Shuichi Kaneko, Toshinari Takamura · 2018 · BMJ Open Diabetes Research & Care
- Secretomics to Discover Regulators in DiseasesParkyong Song, Yonghoon Kwon, Jae‐Yeol Joo, Do-Geun Kim, Jong Hyuk Yoon · 2019 · International Journal of Molecular Sciences
- Central FGF21 production regulates memory but not peripheral metabolismBolu Zhou, Kristin E. Claflin, Kyle H. Flippo, Andrew I. Sullivan, Arvand Asghari, Satya Murthy Tadinada, Sharon O. Jensen-Cody, Ted G. Abel, Matthew J. Potthoff · 2022 · Cell Reports
- Fibroblast growth factor 21 in heart failureWilliam Tucker, Bradley Tucker, Kerry‐Anne Rye, Kwok Leung Ong · 2022 · Heart Failure Reviews
- Association between Circulating Fibroblast Growth Factor 21 and Aggressiveness in Thyroid CancerYea Eun Kang, Jung Tae Kim, Mi Ae Lim, Chan Oh, Lihua Liu, Seung‐Nam Jung, Ho-Ryun Won, Kyung-Min Lee, Jae Won Chang, Hyon‐Seung Yi et al. · 2019 · Cancers
- The ventromedial hypothalamic nucleus: watchdog of whole-body glucose homeostasisLonglong Tu, Makoto Fukuda, Qingchun Tong, Yong Xu · 2022 · Cell & Bioscience
- Therapeutic uses of FGFsJun Zhang, Yang Li · 2015 · Seminars in Cell and Developmental Biology
- Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificityArchita Agrawal, Sebastian Demian Parlee, Diego Pérez–Tilve, Pengyun Li, Jia Hong Pan, Piotr A. Mroz, Ann Maria Kruse Hansen, Birgitte Andersen, Brian Finan, Alexei Kharitonenkov et al. · 2018 · Molecular Metabolism
- Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activityEkaterina S. Kuzina, Peter M.U. Ung, Jyotidarsini Mohanty, Francisco Tomé, Jungyuen Choi, Els Pardon, Jan Steyaert, Irit Lax, Avner Schlessinger, Joseph Schlessinger et al. · 2019 · Proceedings of the National Academy of Sciences
- Protein intake and amino acid supplementation regulate exercise recovery and performance through the modulation of mTOR, AMPK, FGF21, and immunityIván Torre-Villalvazo, Gabriela Alemán, Ricardo Valle‐Rios, Lilia Guadalupe Noriega · 2019 · Nutrition Research
- Curcumin improves insulin sensitivity in high-fat diet-fed mice through gut microbiotaYue Zhong, Yang Xiao, Jing Gao, Zhaozheng Zheng, Ziheng Zhang, Lu Yao, Dongmin Li · 2022 · Nutrition & Metabolism
- Comprehensive amelioration of high-fat diet-induced metabolic dysfunctions through activation of the PGC-1α pathway by probiotics treatment in miceJeonghyeon Kwon, Bobae Kim, Chungho Lee, Hyunchae Joung, Byoung-Kook Kim, In Suk Choi, Chang‐Kee Hyun · 2020 · PLoS ONE
- Steroidal Scaffolds as FXR and GPBAR1 Ligands: From Chemistry to Therapeutical ApplicationValentina Sepe, Eleonora Distrutti, Vittorio Limongelli, Stefano Fiorucci, Angela Zampella · 2015 · Future Medicinal Chemistry
- Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney FunctionSarah Zaheer, Ian H. de Boer, Matthew Allison, Jenifer Michelle Brown, Bruce M. Psaty, Cassianne Robinson‐Cohen, Erin D. Michos, Joachim H. Ix, Bryan R. Kestenbaum, David S. Siscovick et al. · 2017 · The Journal of Clinical Endocrinology & Metabolism
- Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiencyZhen Yan, Ana Kronemberger, Jay Blomme, Jarrod A. Call, Hannah M. Caster, Renata Oliveira Pereira, Henan Zhao, Vitor Ulisses De Melo, Rhianna Che Laker, Mei Zhang et al. · 2017 · Scientific Reports
- The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 DiabetesMaitane Izaguirre, Marı́a J. Gil, Ignacío Monreal, Fabrizio Montecucco, Gema Frühbeck, Victoria Catalán · 2017 · Current Diabetes Reports
- Metformin Therapy Aggravates Neurodegenerative Processes in ApoE –/– MiceAngela Kuhla, Elaine Brichmann, Claire Rühlmann, Robin Thiele, Lou Meuth, Brigitte Vollmar · 2019 · Journal of Alzheimer s Disease
- Transcriptomic Profiling of Skeletal Muscle Reveals Candidate Genes Influencing Muscle Growth and Associated Lipid Composition in Portuguese Local Pig BreedsAndré Albuquerque, Cristina Óvilo, Yolanda Núñez, Rita Benítez, Adrián López-García, Fabián García, Maria do Rosário Félix, Marta Laranjo, Rui Charneca, José Manuel Martins · 2021 · Animals
- Mitochondrial Stress and Mitokines: Therapeutic Perspectives for the Treatment of Metabolic DiseasesBenyuan Zhang, Joon Young Chang, Min Hee Lee, Sang Hyeon Ju, Hyon‐Seung Yi, Minho Shong · 2024 · Diabetes & Metabolism Journal
- Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted stateDandan Guan, Lidan Zhao, Daiwen Chen, Bing Yu, Jie Yu · 2016 · Journal of Translational Medicine
- A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon SecretionPicard, Alexandre, Soyer, Josselin, Berney, Xavier, Tarussio, David, Quenneville, Simon, Jan, Maxime, Grouzmann, Eric, Burdet, Frédéric, Ibberson, Mark, Thorens, Bernard · 2016 · Cell Reports
- FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic CancerNorihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Masashi Toyoda, Murray Korc et al. · 2020 · Cancers
- Modulation of energy balance by fibroblast growth factor 21Daniel Cuevas Ramos, Carlos Alberto Aguilar-Salinas · 2016 · Hormone Molecular Biology and Clinical Investigation
- Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosaEleonora Distrutti, Luca Santucci, Sabrina Cipriani, Barbara Renga, Elisabetta Schiaroli, Patrizia Ricci, Annibale Donini, Stefano Fiorucci · 2015 · Journal of Gastroenterology
- A systems perspective on brown adipogenesis and metabolic activationRachana Pradhan, Magda Zachara, Bart Deplancke · 2017 · Obesity Reviews
- FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS StudyGuo-Hung Li, Jingdong Yin, Junling Fu, Longcan Li, Struan F.A. Grant, Zhongxia Li, M. Li, Jie Mi, M. Li, Shan Gao · 2017 · Diabetes & Metabolism
- Effects of central FGF21 infusion on the hypothalamus–pituitary–thyroid axis and energy metabolism in ratsÜmit Yılmaz, Suat Tekin, Mehmet Tevfik Demir, Yılmaz Çiğremiş, Süleyman Sandal · 2018 · The Journal of Physiological Sciences
- A biparatopic agonistic antibody that mimics fibroblast growth factor 21 ligand activitySally Yu Shi, Ya‐Wen Lu, Zhi Liu, Jennitte L. Stevens, Christopher M. Murawsky, Vicki Wilson, Zhonghua Hu, William G. Richards, Mark Leo Michaels, Jun Zhang et al. · 2018 · Journal of Biological Chemistry
- The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic StressShiori Sekine, Yao Akari, Kazuki Hattori, Sho Sugawara, Isao Naguro, Masato Koike, Yasuo Uchiyama, Kohsuke Takeda, Hidenori Ichijo · 2016 · EBioMedicine
- Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4Kimberly M. Alonge, Gordon P. Meares, F. Bradley Hillgartner · 2017 · Journal of Biological Chemistry
- GSK3 is a negative regulator of the thermogenic program in brown adipocytesLasse Kruse Markussen, Sally Winther, Barton L. Wicksteed, Jacob Bo Hansen · 2018 · Scientific Reports
- KLB gene polymorphism is associated with obesity and non-alcoholic fatty liver disease in the Han ChineseFang Ji, Ye Liu, Jungui Hao, Liping Wang, Ming-Jia Dai, Gui-Fang Shen, Xuebing Yan · 2019 · Aging
- The KLB rs17618244 gene variant is associated with fibrosing MAFLD by promoting hepatic stellate cell activationNadia Panera, Marica Meroni, Miriam Longo, Annalisa Crudele, Luca V. C. Valenti, Emanuele Bellacchio, Luca Miele, Valentina Doria, Erika Paolini, Marco Maggioni et al. · 2021 · EBioMedicine
- Fibroblast growth factor 21 and bone homeostasisYan Tang, Mei Zhang · 2022 · Biomedical Journal
- Fibroblast growth factor 1 levels are elevated in newly diagnosed type 2 diabetes compared to normal glucose tolerance controlsSu Wang, Qichao Yang, Shuqin Yu, Ruirong Pan, Dan Jiang, Yuanxin Liu, Hao Hu, Wenjun Sun, Xiafei Hong, Haoying Xue et al. · 2016 · Endocrine Journal
- Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expressionLiyang Zhao, Jiayi Xu, Zhe Shi, Neal A. Englert, Shuyun Zhang · 2017 · Biochemical Pharmacology
- Fibroblast growth Factor-21 promotes ketone body utilization in neurons through activation of AMP-dependent kinaseYurika Katsu-Jiménez, Alfredo Giménez-Cassina · 2019 · Molecular and Cellular Neuroscience
- Mechanistic insight into nuclear receptor‐mediated regulation of bile acid metabolism and lipid homeostasis by grape seed procyanidin extract (GSPE)Laura E. Downing, Daniel Edgar, Patricia A. Ellison, Marie‐Louise Ricketts · 2017 · Cell Biochemistry and Function
- Effects of supplemented isoenergetic diets varying in cereal fiber and protein content on the bile acid metabolic signature and relation to insulin resistanceWeickert, Martin O., Hattersley, John G., Kyrou, Ioannis, Arafat, Ayman M., Rudovich, Natalia, Roden, Michael, Nowotny, Peter, von Loeffelholz, Christian, Matysik, Silke, Schmitz, Gerd et al. · 2018 · Nutrition & Diabetes
- Farnesoid X receptor modulators (2011 – 2014): a patent reviewValentina Sepe, Eleonora Distrutti, Stefano Fiorucci, Angela Zampella · 2015 · Expert Opinion on Therapeutic Patents
- The Irreversible Covalent Fibroblast Growth Factor Receptor Inhibitor PRN1371 Exhibits Sustained Inhibition of FGFR after Drug ClearanceEleni Venetsanakos, Ken A. Brameld, Vernon T. Phan, Erik J. Verner, Timothy D. Owens, Yan Xing, Danny Tam, Jacob LaStant, Kwan Leung, Dane E. Karr et al. · 2017 · Molecular Cancer Therapeutics
- Therapeutic effect of dichloroacetate against atherosclerosis via hepatic FGF21 induction mediated by acute AMPK activationByong-Keol Min, Chang Joo Oh, Sungmi Park, Ji-Min Lee, Younghoon Go, Bo-Yoon Park, Hyeon‐Ji Kang, Dong Wook Kim, Jeongeun Kim, Eun Kyung Yoo et al. · 2019 · Experimental & Molecular Medicine
- Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21Ricardo Moure, Montserrat Cairó, Samantha Morón‐Ros, Tania Quesada‐López, Laura Campderrós, Rubén Cereijo, Álvaro Hernáez, Francesc Villarroya, Marta Giralt · 2021 · American Journal of Physiology-Endocrinology and Metabolism
- Fibroblast growth factor 21 ameliorates high glucose-induced fibrogenesis in mesangial cells through inhibiting STAT5 signaling pathwayShuai Li, Xiaochen Guo, Teng Zhang, Nan Wang, Junyan Li, Pengfei Xu, Shengqi Zhang, Guiping Ren, Deshan Li · 2017 · Biomedicine & Pharmacotherapy
- Cardiac Fgf21 synthesis and release: an autocrine loop for boosting up antioxidant defenses in failing heartsFabio Di Lisa, Nobuyuki Itoh · 2015 · Cardiovascular Research
- Multiple faces of fibroblast growth factor-23Xiaobin Han, L. Darryl Quarles · 2016 · Current Opinion in Nephrology & Hypertension
- Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factorsMiguel Ruiz-Cruz, Carmen Torres-Granados, Manuel Tena‐Sempere, Juan Roa · 2023 · Current Opinion in Pharmacology
- Metabolism in Retinopathy of PrematurityYohei Tomita, Ayumi Usui‐Ouchi, Anders Nilsson, Jay Yang, Minji Ko, Ann Hellström, Zhongjie Fu · 2021 · Life
- Fibroblast Growth Factor 21 Facilitates the Homeostatic Control of Feeding BehaviorChih-Ting Wu, AKI T.B. CHAFFIN, Karen Koeninger Ryan · 2022 · Journal of Clinical Medicine
- FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetesChristopher Yanucil, Dominik Kentrup, Xueyi Li, Alexander Grabner, Karla J. Schramm, Eliana C. Martinez, Jinliang Li, Isaac D. Campos, Brian A. Czaya, Kylie Heitman et al. · 2022 · Scientific Reports
- Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axisMaría Crespo, Ivana Nikolić, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge Luis Torres, Eva Nóvoa et al. · 2022 · Hepatology
- The fibroblast growth factor system in cognitive disorders and dementiaWujianwen Zhai, Tong Zhang, Yujing Jin, Shijing Huang, Manman Xu, Juhua Pan · 2023 · Frontiers in Neuroscience
- Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita miceIliana López‐Soldado, Joan Josep Guinovart, Jordi Durán · 2021 · Journal of Biological Chemistry
- Nutritional Regulation of Hepatic FGF21 by Dietary Restriction of MethionineHan Fang, Kirsten P. Stone, Laura A. Forney, Desiree Wanders, Thomas W. Gettys · 2021 · Frontiers in Endocrinology
- MicroRNA-34a and Impaired FGF19/21 Signaling in ObesityTing Fu, Jongsook Kim Kemper · 2016 · Vitamins and hormones
- Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cellsZhi Yi Wan, Johann Shane Tian, Hayden Weng Siong Tan, Ai Lee Chow, Arthur Yi Loong Sim, Kenneth Hon-Kim Ban, Yun Chau Long · 2016 · Hepatology
- Fibroblast growth factor 21 regulates glucose metabolism in part by reducing renal glucose reabsorptionShuai Li, Nan Wang, Xiaochen Guo, Junyan Li, Teng Zhang, Guiping Ren, Deshan Li · 2018 · Biomedicine & Pharmacotherapy
- Neuroprotective Effects of the FGF21 Analogue LY2405319Claire Rühlmann, David Dannehl, Marcus Brodtrück, Andrew Charles Adams, Jan Stenzel, Tobias Lindner, Bernd Joachim Krause, Brigitte Vollmar, Angela Kuhla · 2021 · Journal of Alzheimer s Disease
- Adipose tissue autophagy and homeostasis in alcohol-induced liver injuryYuan Li, Wen‐Xing Ding · 2017 · Liver Research
- Neuregulin, an Effector on Mitochondria Metabolism That Preserves Insulin SensitivityAnna Gumà, Francisco Díaz‐Sáez, Marta Camps, António Zorzano · 2020 · Frontiers in Physiology
- Binge drinking episode causes acute, specific alterations in systemic and hepatic inflammation‐related markersEvelina Stankevič, Mads Egerod Israelsen, Helene Bæk Juel, Anne Lundager Madsen, Lars Henrik Ängquist, Peter Aldiss, Nikolaj Torp, Stine Johansen, Camilla Dalby Hansen, Johanne Kragh Hansen et al. · 2023 · Liver International
- FGF21 inhibitor suppresses the proliferation and migration of human umbilical vein endothelial cells through the eNOS/PI3K/AKT pathway.Yumei Li, Jiangnan Huang, Zhiyuan Jiang, Yang Jiao, Hui Wang · 2017 · PubMed Central
- The role of FGF19 in metabolic regulation: insights from preclinical models to clinical trialsMarcela Botelho de Carvalho, Gabriel Machado Chavez Passos Jorge, Luiza Wolf Zanardo, Leticia Miho Hamada, Larissa dos Santos Izabel, Sérgio Santoro, Juliana Magdalon · 2024 · American Journal of Physiology-Endocrinology and Metabolism
- FGF21 Alleviates Hepatic Endoplasmic Reticulum Stress under Physiological ConditionsRyuto Maruyama, Makoto Shimizu, Tsutomu Hashidume, Jun Inoue, Nobuyuki Itoh, Ryuichiro Sato · 2018 · Journal of Nutritional Science and Vitaminology
- Making Way for Suppressing the FGF19/FGFR4 Axis in CancerNéstor Prieto‐Domínguez, Austin Young Shull, Yong Teng · 2018 · Future Medicinal Chemistry
- VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced ObesityBelén Palomares, F. Ruiz-Pino, C. Navarrete, I. Velasco, M. Sánchez-Garrido, C. Jiménez-Jiménez, Carolina Pavicic, M. J. Vazquez, G. Appendino, M. Bellido et al. · 2018 · Scientific Reports
- Fibroblast Growth Factor 19 and Fibroblast Growth Factor 21 Regulation in Obese Diabetics, and Non-Alcoholic Fatty Liver Disease after Gastric BypassJiun‐Yu Guo, Hsin-Hung Chen, Wei‐Jei Lee, Shuchun Chen, Shou‐Dong Lee, Chih‐Yen Chen · 2022 · Nutrients
- Cholic Acid Supplementation of a High-Fat Obesogenic Diet Suppresses Hepatic Triacylglycerol Accumulation in Mice via a Fibroblast Growth Factor 21–Dependent MechanismSiri Manasa Ippagunta, Alexei Kharitonenkov, Andrew Charles Adams, F. Bradley Hillgartner · 2018 · Journal of Nutrition
- Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitmentMarta Giralt, Montserrat Cairó, Francesc Villarroya · 2016 · Best Practice & Research Clinical Endocrinology & Metabolism
- Mechanisms of autophagic responses to altered nutritional statusZhipeng Tao, Hiba Aslam, Jane Parke, Marcel Sanchez, Zhiyong Cheng · 2022 · The Journal of Nutritional Biochemistry
- Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of OsteoarthritisDa-Long Dong, Guang‐Zhen Jin · 2025 · Bioengineering
- The effects of metformin on fibroblast growth factor 19, 21 and fibroblast growth factor receptor 1 in high-fat diet and streptozotocin induced diabetic ratsYan Wang, Ningning Dang, Pei Sun, Jin Xia, Chunxue Zhang, Shuguang Pang · 2017 · Endocrine Journal
- Fibroblast growth factors 19 and 21 in acute liver damageZhao Shan, Gloria Álvarez‐Sola, Iker Uriarte, María Arechederra, Maite G. Fernández‐Barrena, Carmen Berasain, Cynthia Ju, Matias Antonio Avila · 2018 · Annals of Translational Medicine
- KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadismXu C, Andrea Messina, Emmanuel Somm, Hichem Miraoui, Tarja K Kinnunen, James S. Acierno, Nicolas J. Niederländer, Justine Bouilly, Dwyer AA, Yisrael Sidis et al. · 2018 · Yearbook of pediatric endocrinology
- Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in SkinYing Yu, Yingjie Shen, Siyi Zhang, Nan Wang, Lan Luo, Xinyi Zhu, Xiejun Xu, Weitao Cong, Litai Jin, Zhongxin Zhu · 2022 · International Journal of Molecular Sciences
- SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male MiceTomoya Mizumoto, Tatsuya Yoshizawa, Yoshifumi Sato, Takaaki Ito, Tomonori Tsuyama, Akiko Satoh, Satoshi Araki, Kenichi Tsujita, Masaru Tamura, Yuichi Oike et al. · 2022 · Cells
- Association of serum fibroblast growth factor 19 levels with visceral fat accumulation is independent of glucose tolerance statusX. Hu, Q. Xiong, Yu Xu, X. Zhang, Xiaoping Pan, Xiaojing Ma, Yuqian Bao, Weiping Jia · 2017 · Nutrition Metabolism and Cardiovascular Diseases
- Endocrine Adiponectin‐FGF15/19 Axis in Ethanol-Induced Inflammation and Alcoholic Liver InjuryMin You, Zhou Zhou, Michael J. Daniels, Alvin P. Jogasuria · 2017 · Gene Expression
- Transcriptome Comparison Reveals the Difference in Liver Fat Metabolism between Different Sheep BreedsTaotao Li, Meilin Jin, Xiaojuan Fei, Zehu Yuan, Yuqin Wang, Kai Quan, Tingpu Wang, Junxiang Yang, Maochang He, Caihong Wei · 2022 · Animals
- Hepatic HAX-1 inactivation prevents metabolic diseases by enhancing mitochondrial activity and bile salt exportFawzi Alogaili, Sivaprakasam Chinnarasu, Anja Jaeschke, Evangelia Galani Kranias, David Y. Hui · 2020 · Journal of Biological Chemistry
- Glucagon and energy expenditure; Revisiting amino acid metabolism and implications for weight loss therapyHope, D.C.D., Tan, T.M-M. · 2023 · Peptides
- Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel functionLaurent Vachon, Gabriel Jean, Andreea Milasan, Sara Babran, Elizabeth Lacroix, Dainelys Guadarrama Bello, Louis Robert Villeneuve, Janusz W. Rak, Antonio Nanci, Téodora Mihalache-Avram et al. · 2024 · Communications Biology
- FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6Runfeng Wang, Jin Wang, Zhiguo Zhang, Bo Ma, Shukai Sun, Li Gao, Guodong Gao · 2023 · Molecular Medicine
- Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasisRevati S. Dewal, Felix T. Yang, Lisa A. Baer, Pablo Vidal, Diego Hernández‐Saavedra, Nickolai P. Seculov, Adhideb Ghosh, Falko Noé, Olivia Togliatti, Lexis Hughes et al. · 2024 · iScience
- Donepezil improves skeletal muscle insulin resistance in obese mice via the AMPK/FGF21-mediated suppression of inflammation and ferroptosisHyeon Ji Gwon, Wonjun Cho, Sung Woo Choi, Do Su Lim, Esra Çınar Tanrıverdi, A.M. Abd El‐Aty, Ji Hoon Jeong, Tae Woo Jung · 2024 · Archives of Pharmacal Research
- FGF21 Depletion Attenuates Colitis through Intestinal Epithelial IL-22-STAT3 Activation in MiceLiming Liu, Fengyuan Li, Tuo Shao, Lihua Zhang, Jiyeon Lee, Gerald Wayne Dryden, Craig James McClain, Cuiqing Zhao, Wenke Feng · 2023 · Nutrients
- The effects of exercise on FGF21 in adults: a systematic review and meta-analysisLiu, Chuannan, Yan, Xujie, Zong, Yue, He, Yanan, Yang, Guan, Xiao, Yue, Wang, Songtao · 2024 · PeerJ
- βklotho is essential for the anti‐endothelial mesenchymal transition effects of N‐acetyl‐seryl‐aspartyl‐lysyl‐prolineRongfen Gao, Keizo Kanasaki, Jinpeng Li, Munehiro Kitada, Toshiro Okazaki, Daisuke Koya · 2019 · FEBS Open Bio
- Fibroblast growth factor-21 as a novel metabolic factor for regulating thrombotic homeostasisShuai Li, Haibo Jia, Zhihang Liu, Nan Wang, Xiaochen Guo, Muhua Cao, Fang Fang, Jiarui Yang, Junyan Li, Qi He et al. · 2022 · Scientific Reports
- Association of bone biomarkers with advanced atherosclerotic disease in people with overweight/obesityRossella Del Toro, Ilaria Cavallari, Flavia Tramontana, Kyoungmin Park, Rocky Strollo, Luciana Valente, Mariangela De Pascalis, Francesco Grigioni, Paolo Pozzilli, Raffaella Buzzetti et al. · 2021 · Endocrine
- Effects of Weight Loss on FGF-21 in Human Subjects: An Exploratory StudyMichelle Louise Headland, Peter Marshall Clifton, Jennifer Beatrice Keogh · 2019 · International Journal of Environmental Research and Public Health
- CREB Coactivator CRTC2 Plays a Crucial Role in Endothelial FunctionHideaki Kanki, Tsutomu Sasaki, Shigenobu Matsumura, Tomohiro Kawano, Kenichi Todo, Shuhei Okazaki, Kumiko Nishiyama, Hiroshi Takemori, Hideki Mochizuki · 2020 · Journal of Neuroscience
- Leaf extract from Vitis vinifera L. reduces high fat diet-induced obesity in miceMeng Li, Yuehua Jiao, Xiaohong Zhou, Cong Liang, Kexin Yan, Ye Zhao, Xiujie Deng, Xue Han, Yanyan Yang, Hanmin Liu et al. · 2021 · Food & Function
- Fibroblast growth factor 21 and prognosis of patients with cardiovascular disease: A meta-analysisBing Yan, Sicong Ma, Chenghui Yan, Yaling Han · 2023 · Frontiers in Endocrinology
- The fibroblast growth factor–Klotho axis at molecular levelFuqiang Sun, Panpan Liang, Bo Wang, Wenbo Liu · 2023 · Open Life Sciences
- Advances in FGFs for diabetes care applicationsYinai Liu, Qianqian Chen, Yaoqi Li, Liuliu Bi, Zhiying He, Chuxiao Shao, Libo Jin, Renyi Peng, Xingxing Zhang · 2022 · Life Sciences
- Farnesoid X receptor-dependent and -independent pathways mediate the transcriptional control of human fibroblast growth factor 19 by vitamin ADaniel Jahn, D. Sutor, Donata Dorbath, Johannes Weiß, Oliver Götze, Johannes Schmitt, Heike M. Hermanns, Andreas Geier · 2015 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- β‐Klotho sustains postnatal GnRH biology and spins the thread of pubertyMicheline Misrahi · 2017 · EMBO Molecular Medicine