The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
The CCN family of proteins: structure–function relationships
Open accessAbstract
The CCN proteins are key signalling and regulatory molecules involved in many vital biological functions, including cell proliferation, angiogenesis, tumourigenesis and wound healing. How these proteins influence such a range of functions remains incompletely understood but is probably related to their discrete modular nature and a complex array of intra- and inter-molecular interactions with a variety of regulatory proteins and ligands. Although certain aspects of their biology can be attributed to the four individual modules that constitute the CCN proteins, recent results suggest that some of their biological functions require cooperation between modules. Indeed, the modular structure of CCN proteins provides important insight into their structure-function relationships.
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Cited by
Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets
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Metadata
- Authors
- Holbourn, K. P., Acharya, K. R., & Perbal, B.
- Venue
- Trends in Biochemical Sciences
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 33
- Issue
- 10
- Pages
- 461-473
- ISSN
- 0968-0004 (ISSN-L)
- OpenAlex
- W1984841510
- Cited by
- 419
- References
- 101
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Holbourn, K. P., Acharya, K. R., & Perbal, B. (2008). The CCN family of proteins: structure–function relationships. Trends in Biochemical Sciences. https://doi.org/10.1016/j.tibs.2008.07.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
