The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Selenium and selenocysteine: roles in cancer, health, and development
Open accessAbstract
The many biological and biomedical effects of selenium are relatively unknown outside the selenium field. This fascinating element, initially described as a toxin, was subsequently shown to be essential for health and development. By the mid 1990s, selenium emerged as one of the most promising cancer chemopreventive agents, but subsequent human clinical trials yielded contradictory results. However, basic research on selenium continued to move at a rapid pace elucidating its many roles in health, development, and cancer prevention and promotion. Dietary selenium acts principally through selenoproteins, most of which are oxidoreductases involved in diverse cellular functions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The thioredoxin antioxidant system
Lu, J., & Holmgren, A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.07.036 · Cited by 2,055
Moustafa, M. E., Carlson, B. A., El-Saadani, M. A., Kryukov, G. V., Sun, Q.-A., Harney, J. W., Hill, K. E., Combs, G. F., Feigenbaum, L., Mansur, D. B., et al. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.11.3840-3852.2001 · Cited by 131
Self-citationSelenoproteins Are Essential for Proper Keratinocyte Function and Skin Development
Sengupta, A., Lichti, U. F., Carlson, B. A., Ryscavage, A. O., Gladyshev, V. N., Yuspa, S. H., & Hatfield, D. L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012249 · Cited by 109
Self-citation
Cited by
Ferroptosis: Mechanisms and links with diseases
Yan, H.-F., Zou, T., Tuo, Q.-Z., Xu, S., Li, H., Belaidi, A. A., & Lei, P. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00428-9 · Cited by 1,471
Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage.
Karimian, A., Ahmadi, Y., & Yousefi, B. (2016) · DNA Repair · doi:10.1016/j.dnarep.2016.04.008 · Cited by 1,110
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation
Zhang, Y., Swanda, R. V., Nie, L., Liu, X., Wang, C., Lee, H., Lei, G., Mao, C., Koppula, P., Cheng, W., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21841-w · Cited by 698
Selenium for preventing cancer
Vinceti, M., Filippini, T., Del Giovane, C., Dennert, G., Zwahlen, M., Brinkman, M., Zeegers, M. P., Horneber, M., D'Amico, R., & Crespi, C. M. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005195.pub4 · Cited by 649
Current Knowledge on the Importance of Selenium in Food for Living Organisms: A Review
Kieliszek, M., & Błażejak, S. (2016) · Molecules · doi:10.3390/molecules21050609 · Cited by 448
Metadata
- Authors
- Hatfield, D. L., Tsuji, P. A., Carlson, B. A., & Gladyshev, V. N.
- Venue
- Trends in Biochemical Sciences
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 39
- Issue
- 3
- Pages
- 112-120
- ISSN
- 0968-0004 (ISSN-L)
- OpenAlex
- W2065562721
- Cited by
- 714
- References
- 3
- FWCI
- 7.83
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Selenium and selenocysteine: roles in cancer, health, and development. https://app.cochat.ai/papers/10.1016/j.tibs.2013.12.007
- The paper
- Hatfield, D. L., Tsuji, P. A., Carlson, B. A., & Gladyshev, V. N. (2014). Selenium and selenocysteine: roles in cancer, health, and development. Trends in Biochemical Sciences. https://doi.org/10.1016/j.tibs.2013.12.007
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
