The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
Open accessAbstract
In recent years, rapid discoveries have been made relating to Ca2+ handling at specific organelles, which have important implications for whole cell Ca2+ homeostasis. In particular, the structures of the endoplasmic reticulum (ER) Ca2+ channels revealed by electron cryomicroscopy (cryo-EM), the continuous update on the structure, regulation and role of the mitochondrial calcium uniporter (MCU) complex, and the analysis of lysosomal Ca2+ signaling are milestones on the route towards a deeper comprehension of the complexity of global Ca2+ signaling. In this Review, we summarize recent discoveries on the regulation of inter-organellar Ca2+ homeostasis and its role in pathophysiology.
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Cites
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
de Brito, O. M., & Scorrano, L. (2008) · Nature · doi:10.1038/nature07534 · Cited by 2,442
Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ Responses
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Self-citationMitochondria as sensors and regulators of calcium signalling
Rizzuto, R., De Stefani, D., Raffaello, A., & Mammucari, C. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3412 · Cited by 1,781
Self-citationHigh-throughput discovery of novel developmental phenotypes
The International Mouse Phenotyping Consortium, Dickinson, M. E., Flenniken, A. M., Ji, X., Teboul, L., Wong, M. D., White, J. K., Meehan, T. F., Weninger, W. J., Westerberg, H., et al. (2016) · Nature · doi:10.1038/nature19356 · Cited by 1,196
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MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration
Antony, A. N., Paillard, M., Moffat, C., Juskeviciute, E., Correnti, J., Bolon, B., Rubin, E., Csordás, G., Seifert, E. L., Hoek, J. B., et al. (2016) · Nature Communications · doi:10.1038/ncomms10955 · Cited by 206
Cited by
Endoplasmic reticulum-mitochondrial contactology: structure and signaling functions
Csordás, G., Weaver, D., & Hajnóczky, G. (2018) · Trends in Cell Biology · doi:10.1016/j.tcb.2018.02.009 · Cited by 625
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration
Verma, M., Lizama, B. N., & Chu, C. T. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-021-00278-7 · Cited by 451
Biczo, G., Vegh, E. T., Shalbueva, N., Mareninova, O. A., Elperin, J., Lotshaw, E., Gretler, S., Lugea, A., Malla, S. R., Dawson, D., et al. (2018) · Gastroenterology · doi:10.1053/j.gastro.2017.10.012 · Cited by 406
Regulation and Function of Mitochondria–Lysosome Membrane Contact Sites in Cellular Homeostasis
Wong, Y. C., Kim, S., Peng, W., & Krainc, D. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.02.004 · Cited by 341
Mitochondrial Dysfunction in Airway Disease
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Metadata
- Authors
- Raffaello, A., Mammucari, C., Gherardi, G., & Rizzuto, R.
- Venue
- Trends in Biochemical Sciences
- Publisher
- Elsevier BV
- Published
- 2016-12
- Volume
- 41
- Issue
- 12
- Pages
- 1035-1049
- ISSN
- 0968-0004 (ISSN-L)
- OpenAlex
- W2527503499
- Cited by
- 536
- References
- 7
- FWCI
- 2.38
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes. https://app.cochat.ai/papers/10.1016/j.tibs.2016.09.001
- The paper
- Raffaello, A., Mammucari, C., Gherardi, G., & Rizzuto, R. (2016). Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes. Trends in Biochemical Sciences. https://doi.org/10.1016/j.tibs.2016.09.001
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