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Cited by 238

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Design and application of genetically encoded biosensors

Open access
Palmer, Amy E., Qin, Yan, Park, Jungwon Genevieve, McCombs, Janet E.·2011·Trends in Biotechnology

Abstract

In the past 5–10 years, the power of the green fluorescent protein (GFP) and its numerous derivatives has been harnessed toward the development of genetically encoded fluorescent biosensors. These sensors are incorporated into cells or organisms as plasmid DNA, which leads the transcriptional and translational machinery of the cell to express a functional sensor. To date, over 100 different genetically encoded biosensors have been developed for targets as diverse as ions, molecules and enzymes. Such sensors are instrumental in providing a window into the real-time biochemistry of living cells and whole organisms, and are providing unprecedented insight into the inner workings of a cell.

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Crossref · 10.1016/j.tibtech.2010.12.004

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Metadata

Authors
Palmer, A. E., Qin, Y., Park, J. G., & McCombs, J. E.
Venue
Trends in Biotechnology
Publisher
Elsevier BV
Published
2011-03
Volume
29
Issue
3
Pages
144-152
ISSN
0167-7799 (ISSN-L)
OpenAlex
W1966652252
Cited by
238
References
2
FWCI
3.03
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Design and application of genetically encoded biosensors. https://app.cochat.ai/papers/10.1016/j.tibtech.2010.12.004
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Palmer, A. E., Qin, Y., Park, J. G., & McCombs, J. E. (2011). Design and application of genetically encoded biosensors. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2010.12.004

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.