The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Multiplexed Point-of-Care Testing – xPOCT
Open accessAbstract
Multiplexed point-of-care testing (xPOCT), which is simultaneous on-site detection of different analytes from a single specimen, has recently gained increasing importance for clinical diagnostics, with emerging applications in resource-limited settings (such as in the developing world, in doctors' offices, or directly at home). Nevertheless, only single-analyte approaches are typically considered as the major paradigm in many reviews of point-of-care testing. Here, we comprehensively review the present diagnostic systems and techniques for xPOCT applications. Different multiplexing technologies (e.g., bead- or array-based systems) are considered along with their detection methods (e.g., electrochemical or optical). We also address the unmet needs and challenges of xPOCT. Finally, we critically summarize the in-field applicability and the future perspectives of the presented approaches.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The present and future role of microfluidics in biomedical research
Sackmann, E. K., Fulton, A. L., & Beebe, D. J. (2014) · Nature · doi:10.1038/nature13118 · Cited by 2,995
Microfluidic Large-Scale Integration
Thorsen, T., Maerkl, S. J., & Quake, S. R. (2002) · Science · doi:10.1126/science.1076996 · Cited by 2,222
Electrochemical Detection for Paper-Based Microfluidics
Dungchai, W., Chailapakul, O., & Henry, C. S. (2009) · Analytical Chemistry · doi:10.1021/ac9007573 · Cited by 1,224
Commercialization of microfluidic point-of-care diagnostic devices
Chin, C. D., Linder, V., & Sia, S. K. (2012) · Lab on a Chip · doi:10.1039/c2lc21204h · Cited by 1,124
Microfluidics-based diagnostics of infectious diseases in the developing world
Chin, C. D., Laksanasopin, T., Cheung, Y. K., Steinmiller, D., Linder, V., Parsa, H., Wang, J., Moore, H., Rouse, R., Umviligihozo, G., et al. (2011) · Nature Medicine · doi:10.1038/nm.2408 · Cited by 759
Centrifugal microfluidics for biomedical applications
Gorkin, R., Park, J., Siegrist, J., Amasia, M., Lee, B. S., Park, J.-M., Kim, J., Kim, H., Madou, M., & Cho, Y.-K. (2010) · Lab on a Chip · doi:10.1039/b924109d · Cited by 731
Emerging Technologies for Next-Generation Point-of-Care Testing
Vashist, S. K., Luppa, P. B., Yeo, L. Y., Ozcan, A., & Luong, J. H. T. (2015) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.09.001 · Cited by 705
Surface Plasmon Resonance Clinical Biosensors for Medical Diagnostics
Masson, J.-F. (2017) · ACS Sensors · doi:10.1021/acssensors.6b00763 · Cited by 663
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Shao, H., Chung, J., Lee, K., Balaj, L., Min, C., Carter, B. S., Hochberg, F. H., Breakefield, X. O., Lee, H., & Weissleder, R. (2015) · Nature Communications · doi:10.1038/ncomms7999 · Cited by 612
Electrochemical Coding Technology for Simultaneous Detection of Multiple DNA Targets
Wang, J., Liu, G., & Merkoçi, A. (2003) · Journal of the American Chemical Society · doi:10.1021/ja029668z · Cited by 612
Cited by
Electronic Textiles for Wearable Point-of-Care Systems
Chen, G., Xiao, X., Zhao, X., Tat, T., Bick, M., & Chen, J. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00502 · Cited by 688
Detection of Plant Viruses and Disease Management: Relevance of Genetic Diversity and Evolution
Rubio, L., Galipienso, L., & Ferriol, I. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.01092 · Cited by 389
The Era of Digital Health: A Review of Portable and Wearable Affinity Biosensors
Tu, J., Torrente‐Rodríguez, R. M., Wang, M., & Gao, W. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201906713 · Cited by 357
Futuristic biosensors for cardiac health care: an artificial intelligence approach
Vashistha, R., Dangi, A. K., Kumar, A., Chhabra, D., & Shukla, P. (2018) · 3 Biotech · doi:10.1007/s13205-018-1368-y · Cited by 113
Gul, S. S., Abdulkareem, A. A., Sha, A. M., & Rawlinson, A. (2020) · Diagnostics · doi:10.3390/diagnostics10100838 · Cited by 87
Metadata
- Authors
- Dincer, C., Bruch, R., Kling, A., Dittrich, P. S., & Urban, G. A.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 35
- Issue
- 8
- Pages
- 728-742
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2608617863
- Cited by
- 503
- References
- 58
- FWCI
- 4.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Multiplexed Point-of-Care Testing – xPOCT. https://app.cochat.ai/papers/10.1016/j.tibtech.2017.03.013
- The paper
- Dincer, C., Bruch, R., Kling, A., Dittrich, P. S., & Urban, G. A. (2017). Multiplexed Point-of-Care Testing – xPOCT. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2017.03.013
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.