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Cited by 335

The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.

Sex chromosomes and speciation in Drosophila

Open access
Presgraves, Daven C.·2008·Trends in Genetics

Abstract

Two empirical rules suggest that sex chromosomes play a special role in speciation. The first is Haldane's rule— the preferential sterility and inviability of species hybrids of the heterogametic (XY) sex. The second is the disproportionately large effect of the X chromosome in genetic analyses of hybrid sterility. Whereas the causes of Haldane's rule are well established, the causes of the ‘large X-effect’ have remained controversial. New genetic analyses in Drosophila confirm that the X is a hotspot for hybrid male sterility factors, providing a proximate explanation for the large X-effect. Several other new findings— on faster X evolution, X chromosome meiotic drive, and the regulation of the X chromosome in the male-germline— provide plausible evolutionary explanations for the large X-effect.

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Metadata

Authors
Presgraves, D. C.
Venue
Trends in Genetics
Publisher
Elsevier BV
Published
2008-07
Volume
24
Issue
7
Pages
336-343
ISSN
0168-9525 (ISSN-L)
OpenAlex
W1988495007
Cited by
335
References
68
FWCI
1.21
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Sex chromosomes and speciation in Drosophila. https://app.cochat.ai/papers/10.1016/j.tig.2008.04.007
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Presgraves, D. C. (2008). Sex chromosomes and speciation in Drosophila. Trends in Genetics. https://doi.org/10.1016/j.tig.2008.04.007

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