The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Paucity of Genes on the Drosophila X Chromosome Showing Male-Biased Expression
Open accessAbstract
Sex chromosomes are primary determinants of sexual dimorphism in many organisms. These chromosomes are thought to arise via the divergence of an ancestral autosome pair and are almost certainly influenced by differing selection in males and females. Exploring how sex chromosomes differ from autosomes is highly amenable to genomic analysis. We examined global gene expression in Drosophila melanogaster and report a dramatic underrepresentation of X-chromosome genes showing high relative expression in males. Using comparative genomics, we find that these same X-chromosome genes are exceptionally poorly conserved in the mosquito Anopheles gambiae. These data indicate that the X chromosome is a disfavored location for genes selectively expressed in males.
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Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
Edgar, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.207 · Cited by 13,288
Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
Zdobnov, E. M., von Mering, C., Letunic, I., Torrents, D., Suyama, M., Copley, R. R., Christophides, G. K., Thomasova, D., Holt, R. A., Subramanian, G. M., et al. (2002) · Science · doi:10.1126/science.1077061 · Cited by 553
Cited by
The origin of new genes: Glimpses from the young and old
Long, M., Betrán, E., Thornton, K., & Wang, W. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1204 · Cited by 933
The evolution of sex-biased genes and sex-biased gene expression
Ellegren, H., & Parsch, J. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2167 · Cited by 925
In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning
Greco, M., Chiappetta, A., Bruno, L., & Bitonti, M. B. (2012) · Journal of Experimental Botany · doi:10.1093/jxb/err313 · Cited by 538
Xi, Z., Gavotte, L., Xie, Y., & Dobson, S. L. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-1 · Cited by 531
Metadata
- Authors
- Parisi, M., Nuttall, R., Naiman, D., Bouffard, G., Malley, J., Andrews, J., Eastman, S., & Oliver, B.
- Venue
- Science
- Published
- 2003-01-31
- Volume
- 299
- Issue
- 5607
- Pages
- 697-700
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2041358828
- Cited by
- 541
- References
- 2
- FWCI
- 17.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Parisi, M., Nuttall, R., Naiman, D., Bouffard, G., Malley, J., Andrews, J., Eastman, S., & Oliver, B. (2003). Paucity of Genes on the Drosophila X Chromosome Showing Male-Biased Expression. Science. https://doi.org/10.1126/science.1079190
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
