Cytochrome c biogenesis: the Ccm system

Sanders, Carsten; Turkarslan, Serdar; Lee, Dong-Woo; Daldal, Fevzi

doi:10.1016/j.tim.2010.03.006

Cited by 197Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation MechanismsBacterial Genetics and Biotechnology

Cytochrome c biogenesis: the Ccm system

Open access

Sanders, Carsten, Turkarslan, Serdar, Lee, Dong-Woo, Daldal, Fevzi·2010·Trends in Microbiology

DOI 10.1016/j.tim.2010.03.006PMC PMC2916975

Open this paper in CoChat — free account

Abstract

Cytochromes of c-type contain covalently attached hemes that are formed via thioether bonds between the vinyls of heme b and cysteines within C(1)XXC(2)H motifs of apocytochromes. In diverse organisms this post-translational modification relies on membrane-associated specific biogenesis proteins, referred to as cytochrome c maturation (Ccm) systems. A highly complex version of these systems, Ccm or System I, is found in Gram-negative bacteria, archaea and plant mitochondria. We describe emerging functional interactions between the Ccm components categorized into three conserved modules, and present a mechanistic view of the molecular basis of ubiquitous vinyl-2 approximately Cys(1) and vinyl-4 approximately Cys(2) heme b-apocytochrome thioether bonds in c-type cytochromes.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.tim.2010.03.006

Cites

65 of 65 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

These proteins belong to the cytochrome c maturation (Ccm) system I, which is composed of eight constituents (CcmABCDEFGH).
“These proteins belong to the cytochrome c maturation (Ccm) system I, which is composed of eight constituents (CcmABCDEFGH)33,34.”
From AF2Complex predicts direct physical interactions in multimeric proteins with deep learning (2022) · cites this paper as [33]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cytochrome C -Mediated Apoptosis
Jiang, X., & Wang, X. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073706 · Cited by 1,359 · see citing works
Cytochrome C : A Multidisciplinary Approach
Scott, R. A., & Mauk, A. G. (1996) · Medical Entomology and Zoology · Cited by 571 · see citing works
The Purple Phototrophic Bacteria
Hunter, C. N., Daldal, F., Thurnauer, M. C., & Beatty, J. T. (2008) · Advances in photosynthesis and respiration · doi:10.1007/978-1-4020-8815-5 · Cited by 410 · see citing works
Self-citation
Multidisciplinary Approach
(1994) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(18)30526-9 · Cited by 364 · see citing works
Biogenesis of respiratory cytochromes in bacteria
Thöny‐Meyer, L. (1997) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.61.3.337-376.1997 · Cited by 354 · see citing works
Cytochrome c Biogenesis: Mechanisms for Covalent Modifications and Trafficking of Heme and for Heme-Iron Redox Control
Kranz, R. G., Richard-Fogal, C., Taylor, J.-S., & Frawley, E. R. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00001-09 · Cited by 275 · see citing works
Mmicular mechanisms of cytochrome c biogenesis: three distinct systems
Kranz, R. G., Lill, R., Goldman, B. S., Bonnard, G., & Merchant, S. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00869.x · Cited by 257 · see citing works
The chemistry and biochemistry of heme c: functional bases for covalent attachment
Bowman, S., & Bren, K. L. (2008) · Natural Product Reports · doi:10.1039/b717196j · Cited by 200 · see citing works
Prototype of a Heme Chaperone Essential for Cytochrome c Maturation
Schulz, H., Hennecke, H., & Thöny‐Meyer, L. (1998) · Science · doi:10.1126/science.281.5380.1197 · Cited by 196 · see citing works
MauG, a Novel Diheme Protein Required for Tryptophan Tryptophylquinone Biogenesis
Wang, Y., Graichen, M. E., Liu, A., et al. (2003) · Biochemistry · doi:10.1021/bi034243q · Cited by 133 · see citing works
Periplasmic protein thiol:disulfide oxidoreductases ofEscherichia coli
Fabianek, R. A., Hennecke, H., & Thöny‐Meyer, L. (2000) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2000.tb00544.x · Cited by 133 · see citing works
Heme transfer to the heme chaperone CcmE during cytochrome c maturation requires the CcmC protein, which may function independently of the ABC-transporter CcmAB
Schulz, H., Fabianek, R. A., Pellicioli, E. C., Hennecke, H., & Thöny‐Meyer, L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6462 · Cited by 128 · see citing works
Cytochrome c biogenesis in mitochondria
Giegé, P., Grienenberger, J. M., & Bonnard, G. (2007) · Mitochondrion · doi:10.1016/j.mito.2007.10.001 · Cited by 115 · see citing works
Genes required for cytochrome c synthesis inBacillus subtilis
Brun, N. E. L., Bengtsson, J., & Hederstedt, L. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01883.x · Cited by 102 · see citing works
In vitro formation of a c -type cytochrome
Daltrop, O., Allen, J. W. A., Willis, A. C., & Ferguson, S. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132259099 · Cited by 97 · see citing works
A Bacterial Cytochrome c Heme Lyase
Ren, Q., Ahuja, U., & Thöny‐Meyer, L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110979200 · Cited by 96 · see citing works
AtCCMH, an essential component of the c -type cytochrome maturation pathway in Arabidopsis mitochondria, interacts with apocytochrome c
Meyer, E. H., Giegé, P., Gelhaye, É., Rayapuram, N., Ahuja, U., Thöny‐Meyer, L., Grienenberger, J. M., & Bonnard, G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503473102 · Cited by 91 · see citing works
Order within a mosaic distribution of mitochondrial c‐type cytochrome biogenesis systems?
Allen, J. W. A., Jackson, A., Rigden, D. J., Willis, A. C., Ferguson, S. J., & Ginger, M. (2008) · The FEBS Journal · doi:10.1111/j.1742-4658.2008.06380.x · Cited by 88 · see citing works
Novel Rhodobacter capsulatus genes required for the biogenesis of various c‐type cytochromes
Deshmukh, M., Brasseur, G., & Daldal, F. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01683.x · Cited by 88 · see citing works
Self-citation
Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD
Katzen, F., Deshmukh, M., Daldal, F., & Beckwith, J. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf405 · Cited by 87 · see citing works
Self-citation
ABC transporter‐mediated release of a haem chaperone allows cytochrome c biogenesis
Feissner, R. E., Richard‐Fogal, C. L., Frawley, E. R., & Kranz, R. G. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05221.x · Cited by 85 · see citing works
Four genes are required for the system II cytochrome c biogenesis pathway in Bordetella pertussis, a unique bacterial model
Beckett, C. S., Loughman, J. A., Karberg, K. A., et al. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.02174.x · Cited by 84 · see citing works
Biochemical requirements for the maturation of mitochondrial c-type cytochromes
Hamel, P. P., Corvest, V., Giegé, P., & Bonnard, G. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.06.017 · Cited by 79 · see citing works
Structural Basis and Kinetics of DsbD-Dependent Cytochrome c Maturation
Stirnimann, C. U., Rozhkova, A., Grauschopf, U., Grütter, M. G., Glockshuber, R., & Capitani, G. (2005) · Structure · doi:10.1016/j.str.2005.04.014 · Cited by 78 · see citing works
A thioreduction pathway tethered to the membrane for periplasmic cytochromes c biogenesis; in vitro and in vivo studies
Monika, E. M., Goldman, B. S., Beckman, D. L., & Kranz, R. G. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1227 · Cited by 77 · see citing works
Molecular and immunological analysis of an ABC transporter complex required for cytochrome c biogenesis
Goldman, B. S., Beckman, D. L., Bali, A., Monika, E. M., Gabbert, K. K., & Kranz, R. G. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.0992 · Cited by 75 · see citing works
Studies of the Cytochrome Subunits of Menaquinone:Cytochromec Reductase (bc Complex) of Bacillus subtilis
Yu, J. J., & Brun, N. E. L. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.15.8860 · Cited by 70 · see citing works
The Escherichia coli CcmG protein fulfils a specific role in cytochrome c assembly
Reid, E., Cole, J. A., & Eaves, D. J. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3550051 · Cited by 67 · see citing works
A specific c -type cytochrome maturation system is required for oxygenic photosynthesis
Kuras, R., Saint‐Marcoux, D., Wollman, F.-A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702340104 · Cited by 67 · see citing works
A conserved haem redox and trafficking pathway for cofactor attachment
Richard‐Fogal, C. L., Frawley, E. R., Bonner, E. R., Zhu, H., Francisco, B. S., & Kranz, R. G. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.189 · Cited by 66 · see citing works
Structural Basis of Redox-coupled Protein Substrate Selection by the Cytochrome c Biosynthesis Protein ResA
Crow, A., Acheson, R. M., Brun, N. E. L., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402823200 · Cited by 63 · see citing works
The Three Mitochondrial Encoded CcmF Proteins Form a Complex That Interacts with CCMH and c-Type Apocytochromes in Arabidopsis
Rayapuram, N., Hagenmuller, J., Grienenberger, J. M., Bonnard, G., & Giegé, P. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m802621200 · Cited by 61 · see citing works
Maturation of the unusual single-cysteine (XXXCH) mitochondrial c-type cytochromes found in trypanosomatids must occur through a novel biogenesis pathway
Allen, J. W., Ginger, M. L., & Ferguson, S. J. (2004) · Biochemical Journal · doi:10.1042/bj20040832 · Cited by 60 · see citing works
NMR Structure of the Heme Chaperone CcmE Reveals a Novel Functional Motif
Enggist, E., Thöny‐Meyer, L., Güntert, P., & Pervushin, K. V. (2002) · Structure · doi:10.1016/s0969-2126(02)00885-7 · Cited by 60 · see citing works
Cytochrome c assembly: A tale of ever increasing variation and mystery?
Ferguson, S. J., Stevens, J. M., Allen, J. W. A., et al. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2008.03.020 · Cited by 57 · see citing works
Unusual Heme−Histidine Bond in the Active Site of a Chaperone
Lee, D., Pervushin, K. V., Bischof, D., Braun, M., & Thöny‐Meyer, L. (2005) · Journal of the American Chemical Society · doi:10.1021/ja044658e · Cited by 57 · see citing works
Self-citation
AtCCMA Interacts with AtCcmB to Form a Novel Mitochondrial ABC Transporter Involved in Cytochrome c Maturation in Arabidopsis
Rayapuram, N., Hagenmuller, J., Grienenberger, J. M., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704091200 · Cited by 56 · see citing works
Loss of ATP hydrolysis activity by CcmAB results in loss of c‐type cytochrome synthesis and incomplete processing of CcmE
Christensen, O., Harvat, E. M., Thöny‐Meyer, L., Ferguson, S. J., & Stevens, J. M. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05769.x · Cited by 55 · see citing works
A Cytochrome b562 Variant with a c-Type Cytochrome CXXCH Heme-binding Motif as a Probe of the Escherichia coli Cytochrome c Maturation System
Allen, J. W. A., Barker, P. D., & Ferguson, S. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307196200 · Cited by 53 · see citing works
Rhodobacter capsulatus CycH: a bipartite gene product with pleiotropic effects on the biogenesis of structurally different c-type cytochromes
Lang, S. E., Jenney, F. E., & Daldal, F. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.17.5279-5290.1996 · Cited by 51 · see citing works
Self-citation
The Cytochrome c Maturation Components CcmF, CcmH, and CcmI Form a Membrane-integral Multisubunit Heme Ligation Complex
Sanders, C., Turkarslan, S., Lee, D., Önder, Ö., Kranz, R. G., & Daldal, F. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805413200 · Cited by 49 · see citing works
Self-citation
Evolutionary origins of members of a superfamily of integral membrane cytochrome c biogenesis proteins
Lee, J., Harvat, E. M., Stevens, J. M., Ferguson, S. J., & Saier, M. H. (2007) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.04.022 · Cited by 48 · see citing works
Solution Structure and Characterization of the Heme Chaperone CcmE
Arnesano, F., Banci, L., Barker, P. D., Bertini, I., Rosato, A., Su, X., & Viezzoli, M. S. (2002) · Biochemistry · doi:10.1021/bi026362w · Cited by 45 · see citing works
Escherichia coliccm in‐frame deletion mutants can produce periplasmic cytochrome b but not cytochrome c
Throne‐Holst, M., Thöny‐Meyer, L., & Hederstedt, L. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00656-x · Cited by 44 · see citing works
CcmD Is Involved in Complex Formation between CcmC and the Heme Chaperone CcmE during Cytochrome c Maturation
Ahuja, U., & Thöny‐Meyer, L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410912200 · Cited by 42 · see citing works
Compensatory thio–redox interactions between DsbA, CcdA and CcmG unveil the apocytochrome c holdase role of CcmG during cytochrome c maturation
Turkarslan, S., Sanders, C., Ekici, S., & Daldal, F. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06441.x · Cited by 42 · see citing works
Self-citation
Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation
Colbert, C. L., Wu, Q. D., Erbel, P. J. A., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600552103 · Cited by 38 · see citing works
A Strategic Protein in Cytochrome c Maturation
Matteo, A. D., Gianni, S., Schininà, M. E., Giorgi, A., Fabio Altieri, F., Calosci, N., Brunori, M., & Travaglini‐Allocatelli, C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702702200 · Cited by 37 · see citing works
The Dithiol:Disulfide Oxidoreductases DsbA and DsbB of Rhodobacter capsulatus Are Not Directly Involved in Cytochrome c Biogenesis, but Their Inactivation Restores the Cytochrome c Biogenesis Defect of CcdA-Null Mutants
Deshmukh, M., Turkarslan, S., Astor, D., Valkova-Valchanova, M. B., & Daldal, F. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.11.3361-3372.2003 · Cited by 37 · see citing works
Self-citation
CcmF C involved in cytochrome c maturation is present in a large sized complex in wheat mitochondria
Giegé, P., Rayapuram, N., Meyer, E. H., et al. (2004) · FEBS Letters · doi:10.1016/s0014-5793(04)00291-1 · Cited by 36 · see citing works
A variant System I for cytochrome c biogenesis in archaea and some bacteria has a novel CcmE and no CcmH
Allen, J. W. A., Harvat, E. M., Stevens, J. M., & Ferguson, S. J. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.07.073 · Cited by 35 · see citing works
Oxidation−Reduction Properties of Disulfide-Containing Proteins of the Rhodobacter capsulatus Cytochrome c Biogenesis System
Setterdahl, A. T., Goldman, B. S., Hirasawa, M., Jacquot, P., Smith, A. J., Kranz, R. G., & Knaff, D. B. (2000) · Biochemistry · doi:10.1021/bi000663t · Cited by 35 · see citing works
Overproduction of CcmG and CcmFH Rc Fully Suppresses the c -Type Cytochrome Biogenesis Defect of Rhodobacter capsulatus CcmI-Null Mutants
Sanders, C., Deshmukh, M., Astor, D., Kranz, R. G., & Daldal, F. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.12.4245-4256.2005 · Cited by 35 · see citing works
Self-citation
Two Snapshots of Electron Transport across the Membrane
Cho, S., & Beckwith, J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m900651200 · Cited by 33 · see citing works
Evolution of mitochondrial-type cytochrome c domains and of the protein machinery for their assembly
Bertini, I., Cavallaro, G., & Rosato, A. (2007) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2007.02.001 · Cited by 33 · see citing works
In Vitro Synthesis of Oleoylglycine by Cytochrome c Points to a Novel Pathway for the Production of Lipid Signaling Molecules
Mueller, G. P., & Driscoll, W. J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701801200 · Cited by 33 · see citing works
Probing the Heme-Binding Site of the Cytochrome c Maturation Protein CcmE
Harvat, E. M., Redfield, C., Stevens, J. M., & Ferguson, S. J. (2009) · Biochemistry · doi:10.1021/bi801609a · Cited by 33 · see citing works
Membrane-Spanning and Periplasmic Segments of CcmI Have Distinct Functions during Cytochrome c Biogenesis in Rhodobacter capsulatus
Sanders, C., Boulay, C., & Daldal, F. (2006) · Journal of Bacteriology · doi:10.1128/jb.01441-06 · Cited by 25 · see citing works
Self-citation
Control of DegP-Dependent Degradation of c -Type Cytochromes by Heme and the Cytochrome c Maturation System in Escherichia coli
Gao, T., & O’Brian, M. R. (2007) · Journal of Bacteriology · doi:10.1128/jb.00656-07 · Cited by 23 · see citing works
TPR domain of NrfG mediates complex formation between heme lyase and formate‐dependent nitrite reductase in Escherichia coli O157:H7
Han, D., Kim, K., Oh, J., Park, J., & Kim, Y. (2007) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.21597 · Cited by 21 · see citing works
Extracytoplasmic prosthetic group ligation to apoproteins: maturation of c‐type cytochromes
Turkarslan, S., Sanders, C., & Daldal, F. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05148.x · Cited by 21 · see citing works
Self-citation
Overexpression of ccl1−2 can bypass the need for the putative apocytochrome chaperone CycH during the biogenesis of c‐type cytochromes
Deshmukh, M., May, M., Zhang, Y., Gabbert, K. K., Karberg, K. A., Kranz, R. G., & Daldal, F. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03212.x · Cited by 18 · see citing works
Self-citation
Variant c-type cytochromes as probes of the substrate specificity of the E. coli cytochrome c maturation (Ccm) apparatus
Allen, J. W. A., Sawyer, E. B., Ginger, M. L., et al. (2008) · Biochemical Journal · doi:10.1042/bj20081999 · Cited by 17 · see citing works
Biogenesis of c-type Cytochromes and Cytochrome Complexes
Sanders, C., Turkarslan, S., Önder, Ö., Frawley, E. R., Kranz, R. G., Koch, H. G., & Daldal, F. (2008) · Advances in photosynthesis and respiration · doi:10.1007/978-1-4020-8815-5_21 · Cited by 5 · see citing works
Self-citation
Proteins involved in maturation pathways of plant mitochondrial and plastid c-type cytochromes.
Rurek, M. (2008) · Acta Biochimica Polonica · doi:10.18388/abp.2008_3048 · Cited by 5 · see citing works

Flagged first, then by citations

Research works printed but not linked: 1

[1]Pettigrew GW Moore GR Cytochrome c Biological Aspects 1987 Springer Verlag

Sorted by citations

AF2Complex predicts direct physical interactions in multimeric proteins with deep learning
Gao, M., Nakajima An, D., Parks, J. M., & Skolnick, J. (2022) · Nature Communications · doi:10.1038/s41467-022-29394-2 · Cited by 252 · see citing works
The CcmC:Heme:CcmE Complex in Heme Trafficking and Cytochrome c Biosynthesis
Richard-Fogal, C., & Kranz, R. G. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.06.041 · Cited by 53 · see citing works
Architecture of the membrane-bound cytochrome c heme lyase CcmF
Brausemann, A., Zhang, L., Ilcu, L., & Einsle, O. (2021) · Nature Chemical Biology · doi:10.1038/s41589-021-00793-8 · Cited by 29 · see citing works
The <scp>CcmFH</scp> complex is the system <scp>I</scp> holocytochrome c synthetase: engineering cytochrome c maturation independent of <scp>CcmABCDE</scp>
San Francisco, B., Sutherland, M. C., & Kranz, R. G. (2014) · Molecular Microbiology · doi:10.1111/mmi.12510 · Cited by 29 · see citing works
Interaction of HoloCcmE with CcmF in Heme Trafficking and Cytochrome c Biosynthesis
San Francisco, B., & Kranz, R. G. (2014) · Journal of Molecular Biology · doi:10.1016/j.jmb.2013.10.025 · Cited by 24 · see citing works
Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis
Sutherland, M. C., Jarodsky, J. M., Ovchinnikov, S., Baker, D., & Kranz, R. G. (2018) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.01.022 · Cited by 23 · see citing works
The thioreduction component CcmG confers efficiency and the heme ligation component CcmH ensures stereo-specificity during cytochrome c maturation
Verissimo, A. F., Khalfaoui-Hassani, B., Hwang, J., Steimle, S., Selamoglu, N., Sanders, C., Khatchikian, C. E., & Daldal, F. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.794586 · Cited by 21 · see citing works
Self-citation

Thioether ligation in Co(III) complexes with carboxamido nitrogens as donors: implications on the coordination structure of the cobalt site in nitrile hydratase
Tyler, L. A., Olmstead, M. M., & Mascharak, P. K. (2001) · Inorganica Chimica Acta · doi:10.1016/s0020-1693(01)00523-0 · Cited by 28 · see citing works
Recent Progress in Developing Thioether-Containing Ligands for Catalysis Applications
Bellemin‐Laponnaz, S., & Achard, T. (2023) · Synthesis · doi:10.1055/a-2193-4927 · Cited by 19 · see citing works
Phenylation of Platinum(II) Thioether Complexes by Tetraphenylborate(III) in Solid State and Nitromethane Solution
Kukushkin, V. Y., Lövqvist, K., Norén, B., et al. (1993) · Phosphorus, sulfur, and silicon and the related elements · doi:10.1080/10426509308037400 · Cited by 24 · see citing works
A novel thioether linker: Chemical synthesis of a HIV-1 protease analogue by thioether ligation
Englebretsen, D. R., Garnham, B., Bergman, D. A., et al. (1995) · Tetrahedron Letters · doi:10.1016/0040-4039(95)01843-7 · Cited by 54 · see citing works
PHENYLATION OF PLATINUM(II) THIOETHER COMPLEXES BY TETRAPHENYLBORATE(III) IN SOLID STATE AND NITROMETHANE SOLUTION
Yu, V., Kukushkin, Lövqvist, K., et al. (1992) · Phosphorus, sulfur, and silicon and the related elements · doi:10.1080/10426509208034450 · Cited by 1 · see citing works

Authors: Sanders, C., Turkarslan, S., Lee, D.-W., & Daldal, F.
Affiliations: Kutztown University (US)
University of Pennsylvania (US)
Corresponding author: Daldal, Fevzi
ORCID: Turkarslan, Serdar
Daldal, Fevzi
Venue: Trends in Microbiology
Publisher: Elsevier BV
Published: 2010-06
Volume: 18
Issue: 6
Pages: 266-274
ISSN: 0966-842X (ISSN-L)
DOI: 10.1016/j.tim.2010.03.006
PMC: PMC2916975
OpenAlex: W2089527589
Cited by: 197
References: 65
Citations by year: 2026: 7 · 2025: 10 · 2024: 11 · 2023: 17 · 2022: 18 · 2021: 18 · 2020: 11 · 2019: 8 · 2018: 5 · 2017: 6 · 2016: 7 · 2015: 10 · 2014: 7 · 2013: 16 · 2012: 16
FWCI: 0.68
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Microbiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of General Medical Sciences (GM38237, R01GM038237)
Topics: Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Metalloenzymes and iron-sulfur proteins
Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Catalyzed Oxygenation Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: cytochrome c biogenesis, c-type cytochromes, heme b, post-translational modification, Gram-negative bacteria, archaea, plant mitochondria, heme attachment
MeSH terms: Rhodophyta, Archaea, Bacteria, Bacterial Outer Membrane Proteins, Bacterial Proteins, Cysteine, Heme, Mitochondria, Plant Proteins, Plants, Protein Processing, Post-Translational, Sulfides, Archaeal Proteins, Cytochromes c

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Cytochrome c biogenesis: the Ccm system

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks