Cited by 478Obsessive-Compulsive Spectrum DisordersDeep Brain Stimulation and Movement DisordersNeurotransmitter Receptor Influence on Behavior

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Recent advances in Tourette syndrome research

Albin, Roger L., Mink, Jonathan W.·2006·Trends in Neurosciences

DOI 10.1016/j.tins.2006.01.001

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Abstract

Tourette syndrome (TS) is a developmentally regulated neurobehavioral disorder characterized by involuntary, stereotyped, repetitive movements. Recent anatomical and neuroimaging studies have provided evidence for abnormal basal ganglia and dopaminergic function in TS. Basic research on striatal inhibitory mechanisms and dopaminergic function complements the recent neuroimaging and anatomical data. Parallel studies of basal ganglia participation in the normal performance and learning of stereotyped repetitive behaviors or habits has provided additional insight. These lines of research have provided new pieces to the TS puzzle, and their increasing convergence is showing how those pieces can be put together.

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Authors: Albin, R. L., & Mink, J. W.
Affiliations: University of Michigan (US)
University of Rochester Medicine (US)
Corresponding author: Mink, Jonathan W.
ORCID: Albin, Roger L.
Mink, Jonathan W.
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2006-03
Volume: 29
Issue: 3
Pages: 175-182
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2006.01.001
OpenAlex: W2060469305
Cited by: 478
References: 112
Citations by year: 2026: 16 · 2025: 13 · 2024: 14 · 2023: 13 · 2022: 20 · 2021: 20 · 2020: 37 · 2019: 19 · 2018: 19 · 2017: 26 · 2016: 24 · 2015: 33 · 2014: 29 · 2013: 31 · 2012: 27
FWCI: 3.26
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: Tourette syndrome, basal ganglia, dopaminergic activity, habit, neurobehavioral disorders, neuroimaging
MeSH terms: Basal Ganglia, Dopamine, Tourette Syndrome, Humans, Magnetic Resonance Imaging, Organ Size, Research, Tics

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Recent advances in Tourette syndrome research

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