The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia
Watkins, Linda R., Hutchinson, Mark R., Rice, Kenner C., Maier, Steven F.·2009·Trends in Pharmacological Sciences
Cited by (438)
Items 201–300 of 438
- PPARγ activation by pioglitazone does not suppress cravings for alcohol, and is associated with a risk of myopathy in treatment seeking alcohol dependent patients: a randomized controlled proof of principle studyMelanie L. Schwandt, Nancy Diazgranados, John C. Umhau, Laura E. Kwako, David Ted George, Markus A Heilig · 2020 · Psychopharmacology
- Enhancement of meditation analgesia by opioid antagonist in experienced meditatorsMay, Lisa M., Kosek, Peter, Zeidan, Fadel, Berkman, Elliot T. · 2018 · Psychosomatic Medicine
- Chapter 23. Cognitive-Behavioral TherapyKathleen M. Carroll, Brian D. Kiluk · 2021 · American Psychiatric Association Publishing eBooks
- Chapter 27. Family TherapyPeter Steinglass · 2021 · American Psychiatric Association Publishing eBooks
- Chapter 25. Motivational EnhancementMatisyahu Shulman, Katherine Pruzan, Kenneth M. Carpenter · 2021 · American Psychiatric Association Publishing eBooks
- Chapter 44. Mood DisordersJonathan M. Wai, Matisyahu Shulman, Edward V. Nunes · 2021 · American Psychiatric Association Publishing eBooks
- Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of MagnitudeK. J. Gerhold, Ruth Drdla-Schutting, Silke D. Honsek, Liesbeth Forsthuber, Jürgen Sandkühler · 2015 · Journal of Neuroscience
- Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenonLaunette Marie Rieb, Wendy V. Norman, Ruth Elwood Martin, Jonathan Berkowitz, Evan Wood, Ryan McNeil, M‐J Milloy · 2016 · Pain
- Involvement of delta opioid receptors in alcohol withdrawal-induced mechanical allodynia in male C57BL/6 miceDoungkamol Alongkronrusmee, Terrance Chiang, Richard M. van Rijn · 2016 · Drug and Alcohol Dependence
- Stereochemistry and innate immune recognition: (+)‐norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll‐like receptor 4 signalingXiaozheng Zhang, Yinghua Peng, Peter M. Grace, Matthew D. Metcalf, Andrew J. Kwilasz, Yibo Wang, Tianshu Zhang, Siru Wu, Brandon R. Selfridge, Philip S. Portoghese et al. · 2019 · The FASEB Journal
- Alpha-asarone alleviates cutaneous hyperalgesia by inhibiting hyperexcitability and neurogenic inflammation via TLR4/NF-κB/NLRP3 signaling pathway in a female chronic migraine rat modelQi Liu, Ruijie Yan, Ling Wang, Rui Li, Di Zhang, Can Liao, Shengjun Mao · 2024 · Neuropharmacology
- Acute Morphine Exposure Increases the Brain Distribution of [18F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman PrimatesSylvain Auvity, Wadad Saba, Sébastien Goutal, Claire Leroy, Irène Buvat, Jérôme Cayla, Fabien Caillé, Michel Bottlaender, Salvatore Cisternino, Nicolas Tournier · 2016 · The International Journal of Neuropsychopharmacology
- The bivalent ligand MCC22 potently attenuates hyperalgesia in a mouse model of cisplatin-evoked neuropathic pain without tolerance or rewardGiuseppe Cataldo, Samuel J. Erb, Mary M. Lunzer, Nhungoc Luong, Eyup Akgün, Philip S. Portoghese, Julie K. Olson, Donald A. Simone · 2019 · Neuropharmacology
- The Relationship Between Opioids and Immune Signalling in the Spinal CordJacob Thomas, Sanam Mustafa, Jacinta Lee Johnson, Lauren L. Nicotra, Mark Rowland Hutchinson · 2015 · Handbook of experimental pharmacology
- Molecular and cellular basis of mu-opioid receptor signaling: mechanisms underlying tolerance and dependence developmentMichael Swingler, Martina Donadoni, Ellen M. Unterwald, Sanjay B. Maggirwar, Ilker Kudret Sariyer · 2025 · Frontiers in Neuroscience
- Extracellular vesicle-mediated delivery of anti-miR-106b inhibits morphine-induced primary ciliogenesis in the brainRong Ma, Naseer A. Kutchy, Zhongbin Wang, Guoku Hu · 2023 · Molecular Therapy
- Trimethoxyflavanone relieves Paclitaxel-induced neuropathic pain via inhibiting expression and activation of P2X7 and production of CGRP in miceChangqing Mei, Pan Chen, Linbin Xu, Mengmeng Miao, Qichen Lu, Yang Yu, Pengyu Lin, Wenwei Wu, Feng Ni, Yinping Gao et al. · 2023 · Neuropharmacology
- The Use of the Coenzyme Q10 as a Food Supplement in the Management of Fibromyalgia: A Critical ReviewLuca Campisi, Concettina La Motta · 2022 · Antioxidants
- State of the science reviewJohn L. Clifford, Marcie Fowler, Jacob J. Hansen, Bopaiah P. Cheppudira, Jennifer E. Nyland, Margaux M. Salas, Laura L. McGhee, Lawrence N. Petz, Dayna Loyd Averitt · 2014 · The Journal of Trauma: Injury, Infection, and Critical Care
- Chronic Daily Headache: Mechanisms and Principles of ManagementAmy W. Voigt, Harry J. Gould · 2016 · Current Pain and Headache Reports
- Management of Patients With Orofacial Pain and Temporomandibular DisordersGary F. Bouloux, Joli C. Chou, Vincent E. DiFabio, Gregory M. Ness, Daniel Pérez, Louis Gerard Mercuri, William L. Chung, Gary D. Klasser, Steven D. Bender, Steven L. Kraus et al. · 2024 · Journal of Oral and Maxillofacial Surgery
- Clinical Neuroscience of Addiction: Similarities and Differences Between Alcohol and Other DrugsHollis C. Karoly, Sophie L. YorkWilliams, Kent E. Hutchison · 2015 · Alcoholism Clinical and Experimental Research
- CXCL12/CXCR4 Signaling Contributes to the Pathogenesis of Opioid Tolerance: A Translational StudyChih‐Peng Lin, Kai‐Hsiang Kang, Huang‐Ju Tu, Ming‐Yueh Wu, Tzu‐Hung Lin, Houng‐Chi Liou, Wei‐Zen Sun, Wen Fu · 2016 · Anesthesia & Analgesia
- Assessment of pioglitazone and proinflammatory cytokines during buprenorphine taper in patients with opioid use disorderJennifer R. Schroeder, Karran A. Phillips, David H. Epstein, Michelle L. Jobes, Melody A. Furnari, Ashley Kennedy, Markus A Heilig, Kenzie L. Preston · 2018 · Psychopharmacology
- Opioid Adjuvant Strategy: Improving Opioid EffectivenessFrederic J.‐J. Bihel · 2016 · Future Medicinal Chemistry
- Glial cells modulate hippocampal synaptic plasticity in morphine dependent ratsآزاده الهی ماهانی, Soomaayeh Heysieattalab, Narges Hosseinmardi, Mahyar Janahmadi, Fatemehsadat Seyedaghamiri, Habibeh Khoshbouei · 2018 · Brain Research Bulletin
- Cannabinoids, Pain, and Opioid Use Reduction: The Importance of Distilling and Disseminating Existing DataHutchison, Kent E., Hagerty, Sarah L., Galinkin, Jeffrey, Bryan, Angela D., Bidwell, L. Cinnamon · 2019 · Cannabis & Cannabinoid Research
- Cathepsin S in the spinal microglia contributes to remifentanil-induced hyperalgesia in ratsL. Ye, Li Xiao, SY. Yang, JJ. Duan, Y. Chen, Yu Cui, Yuhan Chen · 2016 · Neuroscience
- Potential role of CXCL10/CXCR3 signaling in the development of morphine tolerance in periaqueductal grayWei Wang, Yawen Peng, Hui Yang, Huilian Bu, Genhua Guo, Dai-Qiang Liu, Bin Shu, Xuebi Tian, Ailin Luo, Xuming Zhang et al. · 2017 · Neuropeptides
- Microglial alterations induced by psychoactive drugs: A possible mechanism in substance use disorder?Clarissa Catale, Silvia Bussone, Luisa Lo Iacono, Valeria Carola · 2019 · Seminars in Cell and Developmental Biology
- Glial dysfunction and persistent neuropathic postsurgical painLinda Block · 2015 · Scandinavian Journal of Pain
- Central amygdala inflammation drives pain hypersensitivity and attenuates morphine analgesia in experimental autoimmune encephalomyelitisZoë Dworsky-Fried, Christian A. Faig, Holly A. Vogel, Bradley J. Kerr, Anna M.W. Taylor · 2021 · Pain
- Multiple Sclerosis and the Endogenous Opioid SystemZoë Dworsky-Fried, Caylin I. Chadwick, Bradley J. Kerr, Anna M.W. Taylor · 2021 · Frontiers in Neuroscience
- The opioid antagonist, β-funaltrexamine, inhibits NF-κB signaling and chemokine expression in human astrocytes and in miceRandall L. Davis, Subhas Das, J. Thomas Curtis, Craig W. Stevens · 2015 · European Journal of Pharmacology
- Neuropsychological and neuroanatomical sequelae of chronic non-malignant pain and opioid analgesiaC. Block, L. Cianfrini · 2013 · NeuroRehabilitation (Reading, MA)
- Toll-Like Receptors and ItchTong Liu, Ru‐Rong Ji · 2014 · CRC Press eBooks
- Opioid antagonists for painRobert Taylor, Joseph V. Pergolizzi, Frank Porreca, Robert B. Raffa · 2013 · Expert Opinion on Investigational Drugs
- The use of opioids for treatment of cancer painSebastiano Mercadante · 2014 · Expert Opinion on Pharmacotherapy
- Chronic immune stimulation as a contributing cause of chronic disease in opiate addiction including multi-system ageingAlbert Stuart Reece · 2010 · Medical Hypotheses
- Intraoperative electroacupuncture relieves remifentanil-induced postoperative hyperalgesia via inhibiting spinal glial activation in ratsChang-xi Shi, Yue Liu, Wei Zhang, Yishan Lei, Cui’e Lu, Rao Sun, Yue Sun, Ming Jiang, Xiaoping Gu, Zhengliang Ma · 2017 · Molecular Pain
- Physiopathology of fibromyalgiaDiego Felipe García Rodríguez, Carlos Abud‐Mendoza · 2020 · Reumatología Clínica (English Edition)
- Sex differences in morphine sensitivity are associated with differential glial expression in the brainstem of rats with neuropathic painDamien C. Boorman, Kevin A. Keay · 2022 · Journal of Neuroscience Research
- Mechanisms of Remifentanil-Induced Postoperative Hyperalgesia: A Comprehensive ReviewKexin Zhu, Xiaolin Wen, Xuan Mei, Fang Fang, Tianyao Zhang · 2025 · Drug Design Development and Therapy
- Repeated Use of Morphine Induces Anxiety by Affecting a Proinflammatory Cytokine Signaling Pathway in the Prefrontal Cortex in RatsShamseddin Ahmadi, Shiva Mohammadi Talvar, Kayvan Masoudi, Mohammad Zobeiri · 2022 · Molecular Neurobiology
- Pathophysiology of painStephan Alexander Schug, Helen C.S. Daly, Kathryn J.D. Stannard · 2011 · University of Adelaide Press eBooks
- Reactive microglia after taste nerve injury: comparison to nerve injury models of chronic painDianna L Bartel, Thomas E. Finger · 2013 · F1000Research
- The effect of substance P1–7 amide on nociceptive threshold in diabetic miceMasahiro Ohsawa, Anna Carlsson, Megumi Asato, Takayuki Koizumi, Yuki Nakanishi, Rebecca Fransson, Anja Sandström, Mathias Hallberg, Fred Nyberg, Junzo Kamei · 2010 · Peptides
- Inhibition of morphine tolerance is mediated by painful stimuli via central mechanismsShigeki Iwai · 2012 · Drug Discoveries & Therapeutics
- Evaluation of TSPO PET imaging, a marker of glial activation, to study the neuroimmune footprints of morphine exposure and withdrawalSylvain Auvity, Sébastien Goutal, Benoît Thezé, Catarina Chaves, Benoît Hosten, Bertrand Kühnast, Wadad Saba, Raphaël Boisgard, Irène Buvat, Salvatore Cisternino et al. · 2016 · Drug and Alcohol Dependence
- Attitudes Towards and Management of Opioid-induced HyperalgesiaElena Kum, Norman Buckley, Oscar A. de León-Casasola, Mark J. Lema, Jason Walter Busse · 2020 · Clinical Journal of Pain
- Pathophysiological Mechanisms of Neuropathic PainCaterina Maria Leone, Antonella Biasiotta, Silvia La Cesa, Giulia Di Stefano, G. Cruccu, Andrea Truini · 2011 · Future Neurology
- Glial TLR4 signaling does not contribute to opioid-induced depression of respirationJennifer D. Zwicker, Yong Zhang, Jun Tao Ren, Mark Rowland Hutchinson, Kenner C. Rice, Linda R. Watkins, John J. Greer, Gregory Douglas Funk · 2014 · Journal of Applied Physiology
- Ginger Extract Reduces Chronic Morphine-Induced Neuroinflammation and Glial Activation in Nucleus Accumbens of Rats.Shima Torkzadeh-Mahani, Saeed Esmaeili‐Mahani, Sima Nasri, Fatemeh Darvishzadeh Mahani, Reyhaneh Naderi · 2019 · Europe PMC (PubMed Central)
- Pharmacologic agents directed at the treatment of pain associated with maladaptive neuronal plasticityJoseph V. Pergolizzi, Giustino Varrassi, Peter Magnusson, Frank Breve, Robert B. Raffa, Paul J. Christo, Maninder Chopra, Antonella Paladini, Jo Ann LeQuang, Kailyn Mitchell et al. · 2021 · Expert Opinion on Pharmacotherapy
- Interleukin-1 receptor-associated kinase 4 (IRAK4) in the nucleus accumbens regulates opioid-seeking behavior in male ratsRuyan Wu, Jianfeng Liu, Jimmy Vu, Yufei Huang, David Dietz, Jun‐Xu Li · 2021 · Brain Behavior and Immunity
- Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioidsJacob Thomas, Mark Rowland Hutchinson · 2012 · Expert Review of Neurotherapeutics
- Medical management of acute pain in patients with chronic painMario De Pinto, Alex Cahana · 2012 · Expert Review of Neurotherapeutics
- Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expressionKim Juhani Blomqvist, Hanna Viisanen, Fredrik H.G. Ahlström, Viljami Jokinen, Yulia A. Sidorova, Ilida Suleymanova, Pekka Veli Rauhala, Eija Anneli Kalso, Tuomas Olavi Lilius · 2020 · European Journal of Pharmacology
- Changes in the NMR Metabolic Profile of Human Microglial Cells Exposed to Lipopolysaccharide or MorphineIssam El Ghazi, Wen S. Sheng, Shuxian Hu, Brian G. Reilly, James R. Lokensgard, Robert Bryan Rock, Phillip K. Peterson, George L. Wilcox, Ian M. Armitage · 2010 · Journal of Neuroimmune Pharmacology
- The endocannabinoid system and breathingBeth M. Wiese, Angelica Alvarez Reyes, Todd W. Vanderah, Tally M. Largent‐Milnes · 2023 · Frontiers in Neuroscience
- Neuropeptide and cytokine regulation of pain in the context of substance use disordersElizabeth Delery, Scott Edwards · 2020 · Neuropharmacology
- Viral vector-mediated gene therapy for opioid use disordersTao Wang, Xun Zhu, Hyun Yi, Jun Gu, Shue Liu, Sari Izenwasser, Vance Lemmon, Sabita Roy, Shuanglin Hao · 2021 · Experimental Neurology
- Dexmedetomidine attenuates haemorrhage-induced thalamic pain by inhibiting the TLR4/NF-κB/ERK1/2 pathway in miceTianfeng Huang, Yong Hui Li, Wenqing Hu, Dapeng Yu, Ju Gao, Fan Yang, Yingying Xu, Zehua Wang, Liang Zong · 2021 · Inflammopharmacology
- The Ameliorative Effects of Isorhynchophylline on Morphine Dependence Are Mediated Through the Microbiota-Gut-Brain AxisZhu Chen, Chen Zhijie, Zhou Yuting, Chan Li, Xiao Shilin, Zhou Qichun, Jinying Ou, Jing Li, Luo Chaohua, MO Zhi-xian · 2021 · Frontiers in Pharmacology
- Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-MorbiditySupriya D. Mahajan, Ravikumar Aalinkeel, Neil U. Parikh, Alexander Jacob, Katherine Cwiklinski, Prateet Sandhu, Kevin X. Le, Alexander W. Loftus, Stanley A. Schwartz, Richard John Quigg et al. · 2017 · Immunological Investigations
- Lipid raft disruption as an opportunity for peripheral analgesiaAndrea Kinga Nehr-Majoros, Ágnes Király, Zsuzsanna Helyes, Éva Szőke · 2024 · Current Opinion in Pharmacology
- Potentiation of acute morphine‐induced analgesia measured by a thermal test in bone cancer‐bearing miceSara González‐Rodríguez, Sara Gómez Llames, Agustı́n Hidalgo, Ana Baamonde, Luis Menéndez · 2011 · Fundamental and Clinical Pharmacology
- The “Culture” of Pain Control: A Review of Opioid-Induced Dysbiosis (OID) in Antinociceptive ToleranceRyan A. Mischel, Karan H. Muchhala, William L. Dewey, Hamid I. Akbarali · 2019 · Journal of Pain
- Relative and Age-dependent Stimulation of Soluble and Cellular Immunity in Opiate DependenceAlbert Stuart Reece · 2011 · Journal of Addiction Medicine
- Bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell diseaseGiuseppe Cataldo, Mary M. Lunzer, Julie K. Olson, Eyup Akgün, John D. Belcher, Gregory M. Vercellotti, Philip S. Portoghese, Donald A. Simone · 2018 · Pain
- Identification of Novel Analgesics Through a Drug Repurposing StrategyParisa Gazerani · 2019 · Pain Management
- The ambiguity of opioids revealed by immunology is changing the knowledge and the therapeutic approach in cancer and non-cancer pain: A narrative reviewAngela Santoni, Edoardo Arcuri · 2020 · Immunology Letters
- Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate AdministrationDaniel García‐Pérez, Maria Luisa Laorden, M. Victoria Milanés · 2015 · The International Journal of Neuropsychopharmacology
- Endomorphin analog exhibited superiority in alleviating neuropathic hyperalgesia via weak activation of NMDA receptorsMengtao Ma, Zhaojuan Wang, Jing Wang, Shuang Wei, Jiaming Cui, Yuan Wang, Keyao Luo, Long Zhao, Xin Liu, Rui Wang · 2020 · Journal of Neurochemistry
- The Condition of Neuropathic PainCory C. Toth, Dwight E. Moulin · 2013 · Cambridge University Press eBooks
- Morphine Attenuates Apically-Directed Cytokine Secretion from Intestinal Epithelial Cells in Response to Enteric PathogensAmanda J. Brosnahan, Bryan J. Jones, Cheryl M.T. Dvorak, David R. Brown · 2014 · Pathogens
- Central IRAK-4 kinase inhibition for the treatment of pain following nerve injury in ratsKatrien Pletinckx, Duygu Krings, André Welbers, David A. Rider, Torsten R. Dunkern · 2020 · Brain Behavior and Immunity
- Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodentsTimothy M. Doyle, Mark Rowland Hutchinson, Kathryn Braden, Kali Janes, Vicky Staikopoulos, Zhoumou Chen, William L. Neumann, Sarah Spiegel, Daniela Salvemini · 2020 · Journal of Neuroinflammation
- Current and Evolving Concepts in the Management of Complex Regional Pain Syndrome: A Narrative ReviewBurcu Candan, Semih Güngör · 2025 · Diagnostics
- Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioidsHouan Tu, Kai‐Hsiang Kang, Shih‐Yin Ho, H.C. Liou, Horng‐Huei Liou, C.P. Lin, Wen Fu · 2016 · British Journal of Anaesthesia
- [Toll-like receptor 4: the potential therapeutic target for neuropathic pain].Zejun Jia, Feixiang Wu, Qinghai Huang, Jianmin Liu · 2012 · PubMed
- Hippocampal glial cells modulate morphine-induced behavioral responsesFatemehsadat Seyedaghamiri, Soomaayeh Heysieattalab, Narges Hosseinmardi, Mahyar Janahmadi, آزاده الهی ماهانی, Farhad Salari, Mehdi Golpayegani, Habibeh Khoshbouei · 2018 · Physiology & Behavior
- Contribution of TSPO imaging in the understanding of the state of gliosis in substance use disordersClaire Leroy, Wadad Saba · 2021 · European Journal of Nuclear Medicine and Molecular Imaging
- Receptor Transporter Protein 4 (RTP4) in the Hypothalamus Is Involved in the Development of Antinociceptive Tolerance to MorphineWakako Fujita, Hitoshi Uchida, Masashi Kawanishi, Yusuke Kuroiwa, Manabu Abe, Kenji Sakimura · 2022 · Biomolecules
- Conventional cancer treatment alone or with regional hyperthermia for pain relief in lung cancer: A case–control studyYeon‐Pyo Kim, Yuri Choi, Sun Kim, Yoon-Sung Park, In‐Jae Oh, Kyu‐Sik Kim, Young‐Chul Kim · 2015 · Complementary Therapies in Medicine
- The Melatonin Type 2 Receptor Agonist IIK7 Attenuates and Reverses Morphine Tolerance in Neuropathic Pain Rats Through the Suppression of Neuroinflammation in the Spinal CordYaswanth Kuthati, Chih‐Shung Wong · 2024 · Pharmaceuticals
- Nalmefene non-enantioselectively targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling: wet-lab techniques and in silico simulationsXiaozheng Zhang, Hongshuang Wang, Yibo Wang, Hongyuan Li, Siru Wu, Jingwei Gao, Tianshu Zhang, Jun Xie, Xiaohui Wang · 2021 · Physical Chemistry Chemical Physics
- Glial modulators as novel therapeutics for comorbid pain and opioid use disorderElizabeth K. C. Schwartz, João Paulo De Aquino, Mehmet Sofuoglu · 2024 · British Journal of Clinical Pharmacology
- The protective effect of hydromorphone to ischemia in rat glial cellsYoung Sung Kim, Woon Young Kim, Yeon-Hwa Kim, Ji Won Yoo, Too Jae Min · 2016 · SpringerPlus
- Morphine consumption is associated with systemic inflammation in children undergoing allogeneic hematopoietic stem cell transplantationSilvia De Pietri, B Nielsen, Marianne Ifversen, Katrine Kielsen, Klaus Müller · 2019 · Immunopharmacology and Immunotoxicology
- New pharmacological perspectives and therapeutic options for opioids: Differences matterAndrew A Somogyi, Stefan T Musolino, Daniel Thomas Barratt · 2022 · Anaesthesia and Intensive Care
- Epidemiologic and Molecular Pathophysiology of Chronic Opioid Dependence and the Place of Naltrexone Extended-Release Formulations in its Clinical ManagementAlbert Stuart Reece · 2012 · Substance Abuse Research and Treatment
- Mu opioid receptor regulation of glutamate efflux in the central amygdala in response to predator odorJeffrey Parrilla-Carrero, Kris Ford Kaigler, George H. Hartshorn, Jim R. Fadel, Marlene A. Wilson · 2019 · Neurobiology of Stress
- Comprehensive Mechanisms and Non-Invasive Treatment for Complex Regional Pain Syndrome: A Narrative ReviewHoa Ngan Doan, Min Cheol Chang · 2025 · Journal of Pain Research
- Elevated serum TLR4 level as a potential marker for postsurgical chronic pain in pediatric patients with different approaches to analgesiaYa.V. Semkovych, Dmytro Dmytrіiev · 2022 · Frontiers in Medicine
- Exploration of the Differentially Expressed Long Noncoding RNAs and Genes of Morphine Tolerance via Bioinformatic AnalysisYong Qiu, Ling‐bing Meng, Chenyi Di, Yu-hu Huo, Bo-chen Yao, Tengjiao Zhang, Zhen Hua · 2019 · Journal of Computational Biology
- A review of the genomics of neonatal abstinence syndromeElizabeth Yen, Nathan Gaddis, Lauren L. Jantzie, Jonathan M. Davis · 2023 · Frontiers in Genetics
- Dissecting the innate immune recognition of morphine and its metabolites by TLR4/MD2: an in silico simulation studyXiaozheng Zhang, Ran Li, Haoran Xu, Guicai Wu, Siru Wu, Hongshuang Wang, Yibo Wang, Xiaohui Wang · 2023 · Physical Chemistry Chemical Physics
- Role of phosphodiesterase inhibitor Ibudilast in morphine-induced hippocampal injuryMohsen Zhaleh, Marzieh Panahi, Mehri Ghafouriyan Broujerdnia, Rostam Ghorbani, Kambiz Ahmadi Angali, Ghasem Saki · 2013 · Journal of Injury and Violence Research
- Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancerAtsushi Nakamura, Hiroko Ono, Azusa Ando, Mikie Hinata, Kazuki Niidome, Shigeki Omachi, Gaku Sakaguchi, Shunji Shinohara · 2016 · Journal of Pharmacological Sciences