The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia

Watkins, Linda R., Hutchinson, Mark R., Rice, Kenner C., Maier, Steven F.·2009·Trends in Pharmacological Sciences

Cited by (438)

Items 101–200 of 438

  1. Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation
    Lisa Carole Loram, Frederick R. Taylor, Keith A. Strand, Matthew G. Frank, Paige W. Sholar, Jacqueline A. Harrison, Steven F. Maier, Linda R. Watkins · 2011 · Brain Behavior and Immunity
  2. Neuroimmune modulation of pain and regenerative pain medicine
    Thomas Buchheit, Yul Huh, William D. Maixner, Jianguo Cheng, Ru‐Rong Ji · 2020 · Journal of Clinical Investigation
  3. Analgesia or Addiction?: Implications for Morphine Use after Spinal Cord Injury
    Sarah A. Woller, Georgina L. Moreno, Nigel Hart, Paul Jeff Wellman, James W. Grau, Michelle A. Hook · 2012 · Journal of Neurotrauma
  4. Sex Differences in Innate Immunity and Its Impact on Opioid Pharmacology
    Hillary H. Doyle, Anne Z. Murphy · 2017 · Journal of Neuroscience Research
  5. Opioid-induced hyperalgesia in clinical anesthesia practice
    Lena Weber, David C. Yeomans, Alexander Tzabazis · 2017 · Current Opinion in Anaesthesiology
  6. Impact of sex on pain and opioid analgesia: a review
    Evan F. Fullerton, Hillary H. Doyle, Anne Z. Murphy · 2018 · Current Opinion in Behavioral Sciences
  7. Inhibition of toll-like receptor 4 alleviates hyperalgesia induced by acute dural inflammation in experimental migraine
    Min Su, Ye Ran, Zizi He, Mingjie Zhang, Guanqun Hu, Wenjing Tang, Dengfa Zhao, Shengyuan Yu · 2018 · Molecular Pain
  8. Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming
    Dionéia Araldi, Oliver Bogen, Paul G. Green, Jon D. Levine · 2019 · Journal of Neuroscience
  9. Botulinum toxin A increases analgesic effects of morphine, counters development of morphine tolerance and modulates glia activation and μ opioid receptor expression in neuropathic mice
    Valentina Vacca, Sara Marinelli, Siro Luvisetto, Flaminia Pavone · 2013 · Brain Behavior and Immunity
  10. International Union of Basic and Clinical Pharmacology. XCVI. Pattern Recognition Receptors in Health and Disease
    Clare Elizabeth Bryant, Selinda J. Orr, Brian J. Ferguson, Martyn F. Symmons, Joseph P. Boyle, Tom P. Monie · 2015 · Pharmacological Reviews
  11. Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids
    Gianluigi Tanda, Maddalena Mereu, Takato Hiranita, Juliana C. Quarterman, Mark A. Coggiano, Jonathan L. Katz · 2016 · Neuropsychopharmacology
  12. Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction
    Laura K. Fonken, Matthew G. Frank, Heather M. D’Angelo, Jared D. Heinze, Linda R. Watkins, Christopher A. Lowry, Steven F. Maier · 2018 · Neurobiology of Aging
  13. The present and future of opioid analgesics in small animal practice
    Bradley T. Simon, Paulo V M Steagall · 2016 · Journal of Veterinary Pharmacology and Therapeutics
  14. Molecular mechanisms of morphine tolerance and dependence; novel insights and future perspectives
    Ismail Badshah, Maira Anwar, Babar Murtaza, Muhammad Imran Khan · 2023 · Molecular and Cellular Biochemistry
  15. Cytokine and chemokine profiles in fibromyalgia, rheumatoid arthritis and systemic lupus erythematosus: a potentially useful tool in differential diagnosis
    Daniel J. Wallace, Igor M. Gavin, О. В. Карпенко, Farnaz Barkhordar, Bruce S. Gillis · 2014 · Rheumatology International
  16. Spinal glia and chronic pain
    James Patrick O'Callaghan, Diane Bemis Miller · 2010 · Metabolism
  17. Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis
    Yuhei Irie, Maho Tsubota, Hiroyasu Ishikura, Fumiko Sekiguchi, Yuka Terada, Toshifumi Tsujiuchi, Keyue Liu, Masahiro Nishibori, Atsufumi Kawabata · 2017 · Journal of Neuroimmune Pharmacology
  18. Toll-like receptor 4: A promising crossroads in the diagnosis and treatment of several pathologies
    Miguel M. García, Carlos Goicoechea, Miguel Molina Álvarez, David Pascual · 2020 · European Journal of Pharmacology
  19. Systems and Circuits Linking Chronic Pain and Circadian Rhythms
    Andrew E. Warfield, Jonathan F. Prather, William D. Todd · 2021 · Frontiers in Neuroscience
  20. Interaction of Opioids with TLR4—Mechanisms and Ramifications
    Mai Mahmoud Gabr, Iqira Saeed, Jared A. Miles, Benjamin P. Ross, Paul Nicholas Shaw, Markus Werner Hollmann, Marie‐Odile Parat · 2021 · Cancers
  21. Anti-nociceptive interactions between opioids and a cannabinoid receptor 2 agonist in inflammatory pain
    Matthew B. Yuill, David E. Hale, Josée Guindon, Daniel J. Morgan · 2017 · Molecular Pain
  22. Chronic Cancer Pain: Opioids within Tumor Microenvironment Affect Neuroinflammation, Tumor and Pain Evolution
    Angela Santoni, Matteo Santoni, Edoardo Arcuri · 2022 · Cancers
  23. Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain
    Jeffrey J. Lochhead, Gwen McCaffrey, Lucy Sanchez‐Covarrubias, Jessica D. Finch, Kristin M. DeMarco, Colleen E. Quigley, Thomas P. Davis, Patrick T. Ronaldson · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
  24. Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists
    Xiaozheng Zhang, Fengchao Cui, Hongqian Chen, Tianshu Zhang, Kecheng Yang, Yibo Wang, Zhenyan Jiang, Kenner C. Rice, Linda R. Watkins, Mark Rowland Hutchinson et al. · 2018 · Journal of Chemical Information and Modeling
  25. Mechanisms behind the Development of Chronic Low Back Pain and Its Neurodegenerative Features
    Abdullah Mosabbir · 2022 · Life
  26. Bladder pain relief by HMGB1 neutralization and soluble thrombomodulin in mice with cyclophosphamide-induced cystitis
    Junichi Tanaka, Kaoru Yamaguchi, Hiroyasu Ishikura, Maho Tsubota, Fumiko Sekiguchi, Yukari Seki, Toshifumi Tsujiuchi, Akira Murai, Takehiro Umemura, Atsufumi Kawabata · 2013 · Neuropharmacology
  27. Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague–Dawley rats
    Caitlin K. Posillico, Laurne S. Terasaki, Staci D. Bilbo, Jaclyn M. Schwarz · 2015 · Biology of Sex Differences
  28. Challenges to develop novel anti‐inflammatory and analgesic drugs
    Bálint Botz, Kata Bölcskei, Zsuzsanna Helyes · 2016 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  29. The Relationship Between the Mechanisms of Action and Safety Profiles of Intrathecal Morphine and Ziconotide: A Review of the Literature
    Lynn Roy Webster · 2015 · Pain Medicine
  30. Central neuron-glia interactions and neuropathic pain
    Eduardo Elias Benarroch · 2010 · Neurology
  31. Morphine immunomodulation prolongs inflammatory and postoperative pain while the novel analgesic ZH853 accelerates recovery and protects against latent sensitization
    Amy K. Feehan, James E. Zadina · 2019 · Journal of Neuroinflammation
  32. Interactions of Opioids and HIV Infection in the Pathogenesis of Chronic Pain
    Bolong Liu, Xin Liu, Shao‐Jun Tang · 2016 · Frontiers in Microbiology
  33. Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics
    Nebojša Nick Knežević, Ajay S. Yekkirala, Tony L. Yaksh · 2017 · Anesthesia & Analgesia
  34. Minocycline does not affect experimental pain or addiction-related outcomes in opioid maintained patients
    Caroline A. Arout, Andrew J. Waters, Robert Ross MacLean, Peggy A Compton, Mehmet Sofuoglu · 2018 · Psychopharmacology
  35. P2Y12 receptor-mediated activation of spinal microglia and p38MAPK pathway contribute to cancer-induced bone pain
    Mingjuan Liu, Ming Yao, Hanqi Wang, Longsheng Xu, Ying Zheng, Bing Q. Huang, Huadong Ni, Shijie Xu, Xuyan Zhou, Qingquan Lian · 2017 · Journal of Pain Research
  36. Novel Endomorphin Analogs Are More Potent and Longer-Lasting Analgesics in Neuropathic, Inflammatory, Postoperative, and Visceral Pain Relative to Morphine
    Amy K. Feehan, Jenny Morgenweck, Xing Y. Zhang, Ariel T. Amgott-Kwan, James E. Zadina · 2017 · Journal of Pain
  37. The Italian Society for Rheumatology clinical practice guidelines for the diagnosis and management of fibromyalgia. Best practices based on current scientific evidence
    Alarico Ariani, Laura Bazzichi, Piercarlo Sarzi‐Puttini, Fausto Salaffi, MARIA MANARA, Immacolata Prevete, Alessandra Bortoluzzi, Greta Carrara, Carlo Alberto Scirè, Nicola Ughi et al. · 2021 · Reumatismo
  38. The American Psychiatric Association Publishing Textbook of Substance Use Disorder Treatment
    Kathleen T. Brady, FRANCES RUDNICK LEVIN, Marc S. Galanter, Herbert D. Kleber · 2021 · American Psychiatric Association Publishing eBooks
  39. Morphine increases macrophages at the lesion site following spinal cord injury: Protective effects of minocycline
    Miriam Aceves, Mabel N. Terminel, Andre K. Okoreeh, Alejandro R. Aceves, Yan Ming Gong, Alan Polanco, Farida Sohrabji, Michelle A. Hook · 2019 · Brain Behavior and Immunity
  40. Hypothalamic opioid–Melanocortin appetitive balance and addictive craving
    Albert Stuart Reece · 2010 · Medical Hypotheses
  41. Selective suppression of microglial activation by paeoniflorin attenuates morphine tolerance
    Chun‐Yi Jiang, Long Xu, Liwei Chen, Y. Han, Jinrong Tang, YU-JIE YANG, G. Zhang, W. Liu · 2014 · European Journal of Pain
  42. Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury
    Anna Piotrowska, Ewelina Rojewska, Katarzyna Pawlik, Grzegorz Kreiner, A Ciechanowska, Wioletta Makuch, Irena Nalepa, Joanna Mika · 2019 · Frontiers in Immunology
  43. The impact of cannabinoid type 2 receptors (CB2Rs) in neuroprotection against neurological disorders
    Qing Xin, Fei Xu, Devin H. Taylor, Jingfu Zhao, Jie Wu · 2020 · Acta Pharmacologica Sinica
  44. Anti-superoxide and anti-peroxynitrite strategies in pain suppression
    Kali Janes, William L. Neumann, Daniela Salvemini · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  45. Functions of the Chemokine Receptor CXCR4 in the Central Nervous System and Its Regulation by μ-Opioid Receptors
    Bradley Nash, Olimpia Meucci · 2014 · International review of neurobiology
  46. Antiallodynic effects of propentofylline Elicited by interrupting spinal glial function in a rat model of bone cancer pain
    Ming Yao, Xiang‐yang Chang, Yu‐Xia Chu, Jianping Yang, Li‐na Wang, Hao-qiang Cao, Mingjuan Liu, Qi‐nian Xu · 2011 · Journal of Neuroscience Research
  47. Toxicities associated with head and neck cancer treatment and oncology-related clinical trials
    Alessandro Villa, Stephen T. Sonis · 2016 · Current Problems in Cancer
  48. Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens
    Pan Zhang, Laura S. Moye, Bruce R. Southey, Isaac J. Dripps, Jonathan V. Sweedler, Amynah A. A. Pradhan, Sandra L. Rodriguez‐Zas · 2019 · Molecular Neurobiology
  49. Transgene-mediated expression of tumor necrosis factor soluble receptor attenuates morphine tolerance in rats
    J Sun, S Liu, Marina M. Mata, D J Fink, Shuanglin Hao · 2011 · Gene Therapy
  50. TLR4 Signaling in MPP+-Induced Activation of BV-2 Cells
    Peng Zhou, Ruihui Weng, Zhaoyu Chen, Rui Wang, Jing Zou, Xu Liu, Jinchi Liao, Yanping Wang, Ying Xia, Qing Wang · 2016 · Neural Plasticity
  51. Encyclopedia of Pain
    Gebhart, Gerald F, Schmidt, Robert F · 2013 · Springer eBooks
  52. Toll-like receptor 4 signaling: A common biological mechanism of regimen-related toxicities
    Hannah R. Wardill, Ysabella Z. A. Van Sebille, Kimberley A. Mander, Rachel J. Gibson, Richard M. Logan, Joanne M. Bowen, Stephen T. Sonis · 2014 · Cancer Treatment Reviews
  53. Fisiopatología de la fibromialgia
    Diego Felipe García Rodríguez, Carlos Abud‐Mendoza · 2020 · Reumatología Clínica
  54. Astrocyte-Derived Extracellular Vesicle–Mediated Activation of Primary Ciliary Signaling Contributes to the Development of Morphine Tolerance
    Rong Ma, Naseer A. Kutchy, Guoku Hu · 2021 · Biological Psychiatry
  55. Drug Repositioning: Playing Dirty to Kill Pain
    Leandro Francisco Silva Bastos, Márcio M. Coelho · 2013 · CNS Drugs
  56. Neuroglia and their roles in central respiratory control; an overview
    Gregory Douglas Funk, Vishaal Rajani, Tucaauê Alvares, Ann L. Revill, Yong Zhang, Nathan Y. Chu, Vivian Biancardi, Camila L. Taxini, Alexis Katzell, Robert Reklow · 2015 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
  57. Acute Clinical Predictors of Symptom Recovery in Emergency Department Patients with Uncomplicated Mild Traumatic Brain Injury or Non-Traumatic Brain Injuries
    Lindsay D. Nelson, Robyn E. Furger, Jana Ranson, Sergey S. Tarima, Thomas A. Hammeke, CHRISTOPHER C. RANDOLPH, William Barr, Kevin M. Guskiewicz, Christopher M. Olsen, E. Brooke Lerner et al. · 2017 · Journal of Neurotrauma
  58. Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators
    Ryan A. Mischel, William L. Dewey, Hamid I. Akbarali · 2018 · iScience
  59. The Effect of Morphine on Glial Cells as a Potential Therapeutic Target for Pharmacological Development of Analgesic Drugs
    Haroon Hameed, Mariam Hameed, Paul J. Christo · 2010 · Current Pain and Headache Reports
  60. Scratching activates microglia in the mouse spinal cord
    Ying Zhang, Siok L. Dun, Yi‐Hung Chen, Jin Jun Luo, Alan Cowan, Nae J. Dun · 2014 · Journal of Neuroscience Research
  61. Glial abnormalities in substance use disorders and depression: Does shared glutamatergic dysfunction contribute to comorbidity?
    Mark J. Niciu, Ioline D. Henter, Gerard Sanacora, Carlos A. Zarate · 2013 · The World Journal of Biological Psychiatry
  62. The Emerging Perspective of Morphine Tolerance: MicroRNAs
    Teng-Jiao Zhang, Yong Qiu, Zhen Hua · 2019 · Pain Research and Management
  63. Medications Development for Opioid Abuse
    S. Stevens Negus, Matthew L. Banks · 2012 · Cold Spring Harbor Perspectives in Medicine
  64. Green light exposure elicits anti-inflammation, endogenous opioid release and dampens synaptic potentiation to relieve post-surgical pain.
    Martin, Laurent F., Cheng, Kevin, Washington, Stephanie M., Denton, Millie, Goel, Vasudha, Khandekar, Maithili, Largent-Milnes, Tally M., Patwardhan, Amol, Ibrahim, Mohab M. · 2023 · The Journal of Pain
  65. Chronic cancer and non-cancer pain and opioid-induced hyperalgesia share common mechanisms: neuroinflammation and central sensitization
    Angela Santoni, Sebastiano Mercadante, Edoardo Arcuri · 2021 · Minerva Anestesiologica
  66. Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity
    Junzhi Yang, Bianca G. Reilly, Thomas P. Davis, Patrick T. Ronaldson · 2018 · Pharmaceutics
  67. The cationic amphiphile 3,4-bis(tetradecyloxy)benzylamine inhibits LPS signaling by competing with endotoxin for CD14 binding
    Matteo Piazza, Valentina Calabrese, Chiara Baruffa, Theresa L. Gioannini, Jerrold P Weiss, Francesco Peri · 2010 · Biochemical Pharmacology
  68. Clinical Observation of the Effects of Oral Opioid on Inflammatory Cytokines and Gut Microbiota in Patients with Moderate to Severe Cancer Pain: A Retrospective Cohort Study
    Hanxiang Wang, Juan Luo, Xu Chen, Huiping Hu, Shijun Li, Yu Zhang, Shi Chen · 2022 · Pain and Therapy
  69. Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model
    Raini Dutta, Sabita Roy · 2015 · Journal of Neuroinflammation
  70. Distinct and sex-specific expression of mu opioid receptors in anterior cingulate and somatosensory S1 cortical areas
    Maria Zamfir, Behrang Sharif, Samantha Locke, Aliza T. Ehrlich, Nicole E. Ochandarena, Grégory Scherrer, Alfredo Ribeiro‐da‐Silva, Brigitte Lina Kieffer, Philippe Séguéla · 2022 · Pain
  71. Acute morphine alters GABAergic transmission in the central amygdala during naloxone-precipitated morphine withdrawal: role of cyclic AMP
    Michal Bajo, Samuel G. Madamba, Marisa Roberto, George R. Siggins · 2014 · Frontiers in Integrative Neuroscience
  72. Is There a Role for Opioids in the Treatment of Fibromyalgia?
    Geoffrey Owen Littlejohn, Emma Kathryn Guymer, Gene‐Siew Ngian · 2016 · Pain Management
  73. Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys
    Norikazu Kiguchi, Huiping Ding, Christopher Michael Peters, Nancy D. Kock, Shiroh Kishioka, J. Mark Cline, Janice D. Wagner, Mei‐Chuan Ko · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  74. Design and functional evaluation of an optically active μ-opioid receptor
    Philip A. Barish, Ying Xu, Jianxin Li, Jiao Sun, Yagna P. R. Jarajapu, William O. Ogle · 2013 · European Journal of Pharmacology
  75. Neuraxial TNF and IFN-beta co-modulate persistent allodynia in arthritic mice
    Sarah A. Woller, Cody Ocheltree, Stephanie Y. Wong, Anthony Bui, Yuya Fujita, Gilson Gonçalves dos Santos, Tony L. Yaksh, Maripat Corr · 2018 · Brain Behavior and Immunity
  76. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents
    Timothy M. Doyle, Kali Janes, Zhoumou Chen, Peter M. Grace, Emanuela Esposito, Salvatore Cuzzocrea, Tally M. Largent‐Milnes, William L. Neumann, Linda R. Watkins, Sarah Spiegel et al. · 2020 · Pain
  77. Fibromyalgia and Nutrition: An Updated Review
    Laura Tomaino, Lluís Serra‐Majem, Stefania Martini, Maria Rosaria Ingenito, Paola Rossi, Carlo La Vecchia, Fabrizia Bamonti, Luisella Vigna · 2020 · Journal of the American College of Nutrition
  78. Morphine Preconditioning Protects Against LPS-Induced Neuroinflammation and Memory Deficit
    Farzaneh Rostami, Shahrbanoo Oryan, Abolhassan Ahmadiani, Leila Dargahi · 2012 · Journal of Molecular Neuroscience
  79. Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia
    Masaud Shah, Sangdun Choi · 2017 · Frontiers in Immunology
  80. Chapter 13. Methadone and Buprenorphine Maintenance Treatment of Opioid-Related Disorders
    Eric C. Strain, Kenneth B. Stoller · 2021 · American Psychiatric Association Publishing eBooks
  81. One immune system plays many parts: The dynamic role of the immune system in chronic pain and opioid pharmacology
    Sanam Mustafa, Juliana Esma Bajic, Benjamin Barry, Samuel G. Evans, Kariel R. Siemens, Mark Rowland Hutchinson, Peter M. Grace · 2023 · Neuropharmacology
  82. Botulinum neurotoxin A enhances the analgesic effects on inflammatory pain and antagonizes tolerance induced by morphine in mice
    Valentina Vacca, Sara Marinelli, Cecilia Eleuteri, Siro Luvisetto, Flaminia Pavone · 2012 · Brain Behavior and Immunity
  83. The Effects of the Toll-Like Receptor 4 Antagonist, Ibudilast, on Sevoflurane’s Minimum Alveolar Concentration and the Delayed Remifentanil-Induced Increase in the Minimum Alveolar Concentration in Rats
    Daniel Ruiz-Pérez, Javier Benito, Gonzalo Polo-Paredes, Carlota Largó, Delia Aguado, Luis Angel Rioja Sanz, Ignacio Álvarez Gómez de Segura · 2016 · Anesthesia & Analgesia
  84. Chapter 2. Genetics and Epigenetics of Addiction
    Joel E. Gelernter, Renato A Polimanti · 2021 · American Psychiatric Association Publishing eBooks
  85. Chapter 37. Substance-Related Disorders in Adolescents
    Amanda T. Roten, Kevin M. Gray · 2021 · American Psychiatric Association Publishing eBooks
  86. Chapter 3. Epidemiology of Addiction
    Nathan Smith, Linda Bauer Cottler · 2021 · American Psychiatric Association Publishing eBooks
  87. Glial Activation, Neuroinflammation, and Loss of Neuroprotection in Chronic Pain: Cellular Mechanisms and Emerging Therapeutic Strategies
    Alyssa McKenzie, Rachel Dombrower, Nitchanan Theeraphapphong, Sophia M. McKenzie, Munther A. Hijazin · 2025 · Biomedicines
  88. Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury
    Miriam Aceves, Benson Mathai, Michelle A. Hook · 2016 · Spinal Cord
  89. Pharmacotherapy in fibromyalgia (FM) — Implications for the underlying pathophysiology
    Tobias Schmidt‐Wilcke, Daniel Joseph Clauw · 2010 · Pharmacology & Therapeutics
  90. In Vitro Nociceptor Neuroplasticity Associated with In Vivo Opioid-Induced Hyperalgesia
    Eugen V. Khomula, Dionéia Araldi, Jon D. Levine · 2019 · Journal of Neuroscience
  91. Translational potential of naloxone and naltrexone as TLR4 antagonists
    Phil Skolnick, Hirsch D. Davis, Derrick R. Arnelle, Daniel R. Deaver · 2014 · Trends in Pharmacological Sciences
  92. Chapter 48. Trauma- and Stressor-Related Disorders
    Skye Fitzpatrick, Amber M. Jarnecke, Sudie E. Back, Elizabeth Straus, Sonya Norman, Denise A. Hien · 2021 · American Psychiatric Association Publishing eBooks
  93. Role of Spinal CXCL1 (GROα) in Opioid Tolerance
    Chih‐Peng Lin, Kai‐Hsiang Kang, Tzu-Hung Lin, Ming-Yueh Wu, Houng‐Chi Liou, Woei‐Jer Chuang, Wei‐Zen Sun, Wen Fu · 2014 · Anesthesiology
  94. Preventive and Alleviative Effect of Tramadol on Neuropathic Pain in Rats: Roles of α2-Adrenoceptors and Spinal Astrocytes
    Minoru Sakakiyama, Sanae Maeda, Kouichi Isami, Kayoko Asakura, Kanako So, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko · 2014 · Journal of Pharmacological Sciences
  95. Imaging Biomarkers of the Neuroimmune System among Substance Use Disorders: A Systematic Review
    Eric A. Woodcock, Ansel T. Hillmer, Graeme F. Mason, Kelly Cosgrove · 2019 · Complex Psychiatry
  96. Chapter 35. Prevention of Substance Use Disorders
    Katrina Elizabeth Champion, Nicola C. Newton, Maree Teesson · 2021 · American Psychiatric Association Publishing eBooks
  97. The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users
    Jermaine D. Jones, Maria A. Sullivan, Jeanne M. Manubay, Shanthi Mogali, Verena E. Metz, Roberto Ciccocioppo, Sandra D. Comer · 2015 · Physiology & Behavior
  98. Potentiation of buprenorphine antinociception with ultra‐low dose naltrexone in healthy subjects
    Justin L. Hay, S.F. La Vincentel, A.A. Somogyil, C.B. Chapleol, Jason M. White · 2010 · European Journal of Pain
  99. Pharmacological relationship between nicotinic and opioid systems in analgesia and corticosterone elevation
    Akihiro Yamamoto, Norikazu Kiguchi, Yuka Kobayashi, Takehiko Maeda, Keiko Ueno, Chizuko Yamamoto, Shiroh Kishioka · 2011 · Life Sciences
  100. The Immune System and the Developing Brain
    Jaclyn M. Schwarz, Staci D. Bilbo · 2011 · Colloquium Series on The Developing Brain