P2X7 receptor: an emerging target in central nervous system diseases

Sperlágh, Beáta, Illes, Peter·2014·Trends in Pharmacological Sciences

Cited by (396)

Items 201–300 of 396

  1. Radioligands targeting purinergic P2X7 receptor
    Qi‐Huang Zheng · 2020 · Bioorganic & Medicinal Chemistry Letters
  2. Tetramisole and Levamisole Suppress Neuronal Activity Independently from Their Inhibitory Action on Tissue Non-specific Alkaline Phosphatase in Mouse Cortex
    Lionel G. Nowak, Benoît Rosay, Dávid Czégé, Caroline Fonta · 2015 · Sub-cellular biochemistry/Subcellular biochemistry
  3. Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model
    Jacob A. Irwin, Alev Erişir, Inchan Kwon · 2016 · Current Alzheimer Research
  4. Substituted 5,6-(Dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-methanones as P2X7 Antagonists
    Jeannie Ziff, Dale A. Rudolph, Brice Stenne, Tatiana B. Koudriakova, Brian Lord, Pascal Bonaventure, Timothy W. Lovenberg, Nicholas I. Carruthers, Anindya Bhattacharya, Michael A. Letavic et al. · 2016 · ACS Chemical Neuroscience
  5. P2X7 receptors exert a permissive effect on the activation of presynaptic AMPA receptors in rat trigeminal caudal nucleus glutamatergic nerve terminals
    Currò, Diego, Navarra, Pierluigi, Samengo, Irene, Martire, Maria · 2020 · The Journal of Headache and Pain
  6. Microarray Profile of Long Noncoding RNA and Messenger RNA Expression in a Model of Alzheimer’s Disease
    Linlin Wang, Li Zeng, Hailun Jiang, Zhuorong Li, Rui Liu · 2020 · Life
  7. Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease
    Deidiane Elisa Ribeiro, Lyvia Lintzmaier Petiz, Talita Glaser, Ágatha Oliveira‐Giacomelli, Roberta Andrejew, Fernando de Azevedo Ribeiro Saab, Milena da Silva Milanis, Henrique Correia Campos, Vanessa Fernandes Arnaud-Sampaio, Sophia La Banca de Oliveira et al. · 2022 · Neuropharmacology
  8. Enteric glial cells immunoreactive for P2X7 receptor are affected in the ileum following ischemia and reperfusion
    Cristina Eusébio Mendes, Kelly Palombit, Wothan Tavares-de-Lima, Patrícia Castelucci · 2019 · Acta Histochemica
  9. Synthesis and initial in vitro characterization of a new P2X7R radioligand [18F]IUR-1602
    Mingzhang Gao, Min Wang, Barbara E. Glick‐Wilson, Jill A. Meyer, Jonathan S. Peters, Paul R. Territo, Mark A. Green, Gary D. Hutchins, Hamideh Zarrinmayeh, Qi‐Huang Zheng · 2018 · Applied Radiation and Isotopes
  10. The neurobiological mechanisms and therapeutic prospect of extracellular ATP in depression
    Kaixin Wang, Shiqian Huang, Daan Fu, Xinxin Yang, Lulin Ma, Tianhao Zhang, Wenjing Zhao, Daling Deng, Yuanyuan Ding, Yanyan Zhang et al. · 2024 · CNS Neuroscience & Therapeutics
  11. Characterization of the Novel P2X7 Receptor Radioligand [3H]JNJ-64413739 in Human Brain Tissue
    Jens Damsgaard Mikkelsen, Sanjay S. Aripaka, Sif Kaad, Burcu Azak Pazarlar, Lars Hageman Pinborg, Bente R. Finsen, Andrea Varrone, Benny Bang‐Andersen, Jesper F. Bastlund · 2022 · ACS Chemical Neuroscience
  12. Understanding autoimmunity: The ion channel perspective
    Anantha Maharasi Ramakrishnan, Kavitha Sankaranarayanan · 2016 · Autoimmunity Reviews
  13. P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period
    Po Gao, Xiaowei Ding, Tahir Muhammad Khan, Weifang Rong, Heike Franke, Péter Illés · 2017 · Neuroscience
  14. How to influence the mesenchymal stem cells fate? Emerging role of ectoenzymes metabolizing nucleotides
    Katarzyna Roszek, Magdalena Wujak · 2018 · Journal of Cellular Physiology
  15. Purinergic Signaling and Cochlear Injury-Targeting the Immune System?
    László Köles, Judit Szepesy, Eszter Berekméri, Tibor Zelles · 2019 · International Journal of Molecular Sciences
  16. LPS-Induced Systemic Neonatal Inflammation: Blockage of P2X7R by BBG Decreases Mortality on Rat Pups and Oxidative Stress in Hippocampus of Adult Rats
    Clivandir Severino da Silva, Michele Longoni Calió, Amanda Cristina Mosini, Jaime Moreira Pires, Débora Bandeira Rêgo, Luiz E. Mello, Ana Teresa Figueiredo Stochero Leslie · 2019 · Frontiers in Behavioral Neuroscience
  17. Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy
    Péter Illés, Patrizia Rubini, Henning Ulrich, Haiyan Yin, Yong Cheng Tang · 2025 · MedComm
  18. Alcohol intake in two different mouse drinking models after recovery from the lipopolysaccharide-induced sickness reaction
    Mira Lainiola, Anni-Maija Linden · 2017 · Alcohol
  19. Specific Temporal Distribution and Subcellular Localization of a Functional Vesicular Nucleotide Transporter (VNUT) in Cerebellar Granule Neurons
    Aida Menéndez‐Méndez, Juan Ignacio Díaz‐Hernandéz, Felipe Ortega, Javier Gualix, Rosa Gómez‐Villafuertes, María Teresa Miras‐Portugal · 2017 · Frontiers in Pharmacology
  20. Coordinate effects of P2X7 and extracellular acidification in microglial cells
    Ponarulselvam Sekar, Duen-Yi Huang, Shwu‐Fen Chang, Wan‐Wan Lin · 2018 · Oncotarget
  21. P2X receptors in maintenance and differentiation of neural progenitor cells
    Henning Ulrich, Péter Illés · 2014 · Neural Regeneration Research
  22. Selective nitration of Hsp90 acts as a metabolic switch promoting tumor cell proliferation
    Isabelle E. Logan, Kyle T. Nguyen, Tilottama Chatterjee, Bhagyashree Manivannan, Ngozi P. Paul, Sharon Kim, Evelyn Sixta, Lydia P. Bastian, Carrie L. Marean‐Reardon, Matthias A. Karajannis et al. · 2024 · Redox Biology
  23. P2X7 Receptor-Dependent Layer-Specific Changes in Neuron-Microglia Reactivity in the Prefrontal Cortex of a Phencyclidine Induced Mouse Model of Schizophrenia
    Stefano Calovi, Paula Mut-Arbona, Pál Tod, András Iring, Annette Nicke, Susana Mato, E. Sylvester Vizi, Jan Tønnesen, Beáta Sperlágh · 2020 · Frontiers in Molecular Neuroscience
  24. More than a drug target: Purinergic signalling as a source for diagnostic tools in epilepsy
    Zheng Wei Wong, Tobías Engel · 2022 · Neuropharmacology
  25. Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development
    Paula Mut-Arbona, Lumei Huang, Mária Baranyi, Pál Tod, András Iring, Francesco Calzaferri, Cristóbal de los Rı́os, Beáta Sperlágh · 2023 · Journal of Neuroscience
  26. Antinociceptive and neuroprotective effect of echinacoside on peripheral neuropathic pain in mice through inhibiting P2X7R/FKN/CX3CR1 pathway
    Ning Liu, Guoxin Zhang, Chunhao Zhu, Xiaobing Lan, Miaomiao Tian, Ping Zheng, Xiao-Dong Peng, Yu‐Xiang Li, Jianqiang Yu · 2023 · Biomedicine & Pharmacotherapy
  27. Microglial purinergic signaling in Alzheimer’s disease
    Shu-Ya Mei, Ning Zhang, Mengjing Wang, Pei-ran Lv, Qi Liu · 2024 · Purinergic Signalling
  28. Beyond monoamines: I. Novel targets and radiotracers for Positron emission tomography imaging in psychiatric disorders
    Brian J. Lopresti, Sarah K. Royse, Chester A. Mathis, Savannah Tollefson, Rajesh Narendran · 2022 · Journal of Neurochemistry
  29. High Level P2X7-Mediated Signaling Impairs Function of Hematopoietic Stem/Progenitor Cells
    Wenli Feng, Feifei Yang, Rong Wang, Xiao Qi Yang, Lina Wang, Chong Chen, Jinfeng Liao, Yong‐Min Lin, Qian Ren, Guoguang Zheng · 2016 · Stem Cell Reviews and Reports
  30. Impaired calcium signalling and neuropsychiatric disorders in Darier disease: An exploratory review
    Austin B. Ambur, Asma Zaidi, Charles Dunn, Rajiv Nathoo · 2022 · Experimental Dermatology
  31. Positron Emission Tomography of Neuroimmune Responses in Humans: Insights and Intricacies
    Nakul Ravi Raval, Reagan R. Wetherill, Corinde E. Wiers, Jacob G. Dubroff, Ansel T. Hillmer · 2022 · Seminars in Nuclear Medicine
  32. P2 receptor-mediated signaling in the physiological and pathological brain: From development to aging and disease
    Paula Mut-Arbona, Beáta Sperlágh · 2023 · Neuropharmacology
  33. Synthesis and in vitro biological evaluation of new P2X7R radioligands [11C]halo-GSK1482160 analogs
    Mingzhang Gao, Min Wang, Jill A. Meyer, Paul R. Territo, Gary D. Hutchins, Hamideh Zarrinmayeh, Qi‐Huang Zheng · 2019 · Bioorganic & Medicinal Chemistry Letters
  34. Duality of P2X7 Receptor in Amyotrophic Lateral Sclerosis
    Cinzia Volonté, Susanna Amadio, Francesco Liguori, Paola Fabbrizio · 2020 · Frontiers in Pharmacology
  35. Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotors
    Fengmei Pi, Mario Vieweger, ZhengYi John Zhao, Shaoying Wang, Peixuan Guo · 2015 · Expert Opinion on Drug Delivery
  36. Neurogenic Differentiation of Mesenchymal Stem Cells Induces Alterations in Extracellular Nucleotides Metabolism
    Joanna Czarnecka, Dorota Porowińska, Anna Bajek, Marcin Hołysz, Katarzyna Roszek · 2016 · Journal of Cellular Biochemistry
  37. Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs
    Felipe Ortega, Rosa Gómez‐Villafuertes, María Benito-León, Margaret Martínez de la Torre, Luis Alcides Olivos-Oré, Marina Arribas-Blázquez, María Victoria Gómez‐Gaviro, Arturo Azcorra, Manuel Desco, Antonio R. Artalejo et al. · 2021 · Brain Structure and Function
  38. Pharmacological evaluation of a novel series of urea, thiourea and guanidine derivatives as P2X7 receptor antagonists
    Erick C.N. Wong, Tristan A. Reekie, Eryn L. Werry, James O’Brien-Brown, Sarah L. Bowyer, Michael Kassiou · 2017 · Bioorganic & Medicinal Chemistry Letters
  39. Regulation of Pannexin 1 Surface Expression by Extracellular ATP: Potential Implications for Nervous System Function in Health and Disease
    Leigh Anne Swayne, Andrew K. J. Boyce · 2017 · Frontiers in Cellular Neuroscience
  40. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice
    Giorgia Conte, Thanh Ngoc Nguyen, Mariana Alves, Laura de Diego-García, Aidan Kenny, Annette Nicke, David Clifford Henshall, Eva Maria Jimenez-Mateos, Tobías Engel · 2020 · Frontiers in Molecular Neuroscience
  41. Inhibition of P2X7R alleviates neuroinflammation and brain edema after traumatic brain injury by suppressing the NF-κB/NLRP3 inflammasome pathway
    Bingyan Tao, Jie Pei, Hao Li, Guochao Yang, Xudong Shi, Zehan Zhang, Hui Wang, Zheng Zhou, Yuyang Liu, Jun Zhang · 2024 · Journal of Neurorestoratology
  42. Oxidative stress-induced increase of intracellular zinc in astrocytes decreases their functional expression of P2X7 receptors and engulfing activity
    Takahiro Furuta, Ayumi Mukai, Akihiro Ohishi, Kentaro Nishida, Kazuki Nagasawa · 2017 · Metallomics
  43. Modulation of rat synaptosomal ATPases and acetylcholinesterase activities induced by chronic exposure to the static magnetic field
    Marko Dinčić, Danijela Z. Krstic, Mirjana B. Čolović, Jelena Nešović Ostojić, Sanjin Kovačević, Silvio R. De Luka, Drago M. Djordjevic, Sasa T. Cirkovic, Predrag Brkić, Jasna Todorović · 2018 · International Journal of Radiation Biology
  44. The effects of P2X7 receptor knockout on emotional conditions over the lifespan of mice
    Liangcai Gao, Zejie Lin, Guixiang Xie, Tian Gang Zhou, Wenhao Hu, Chi Liu, Xinnan Liu, Xinyi Wang, Min Qian, Bing Ni · 2018 · Neuroreport
  45. Microglia-Astrocyte Crosstalk in Post-Stroke Neuroinflammation: Mechanisms and Therapeutic Strategies
    Tong Shang, Binglin Kuang, Yaxin Shang, Wei Zou · 2025 · Current Neuropharmacology
  46. P2X7 Receptors in Astrocytes: A Switch for Ischemic Tolerance
    Yuri Hirayama, Naohiko Anzai, Hiroyuki Kinouchi, Schuichi Koizumi · 2022 · Molecules
  47. Purinergic Receptors P2X7 and P2X4 as Markers of Disease Progression in the rd10 Mouse Model of Inherited Retinal Dystrophy
    Natalia Martínez‐Gil, Oksana Kutsyr, Agustina Noailles, Laura Fernández‐Sánchez, Lorena Vidal, Xavier Sánchez‐Sáez, Carla Sánchez‐Castillo, Pedro Lax, Nicolás Cuenca, Antonio G. Garcı́a et al. · 2022 · International Journal of Molecular Sciences
  48. Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation
    Zsüliet Kristóf, Zsófia Gál, Dóra Török, Nóra Eszlári, Sára Sütöri, Berta Erdelyi-Hamza, Péter Petschner, Beáta Sperlágh, Ian Muir Anderson, J.F.W. Deakin et al. · 2023 · Scientific Reports
  49. New Kid on the Block: Does Histamine Get Along with Inflammation in Amyotrophic Lateral Sclerosis?
    Cinzia Volonté, Chiara Parisi, Savina Apolloni · 2015 · CNS & Neurological Disorders - Drug Targets
  50. Functional P2X7Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia
    Sílvia Prades, Gregory Heard, Jonathan E. Gale, Tobías Engel, Robin Kopp, Annette Nicke, Katie E. Smith, Daniel J. Jagger · 2021 · Journal of Neuroscience
  51. Elevated Serum Purine Levels in Schizophrenia: A Reverse Translational Study to Identify Novel Inflammatory Biomarkers
    Zsüliet Kristóf, Mária Baranyi, Pál Tod, Paula Mut-Arbona, Kornél Demeter, István Bitter, Beáta Sperlágh · 2022 · The International Journal of Neuropsychopharmacology
  52. MicroRNA: Crucial modulator in purinergic signalling involved diseases
    Jing Guo, Peng Yang, Yifan Li, Jinfan Tang, Zhaoxuan He, Shuguang Yu, Haiyan Yin · 2022 · Purinergic Signalling
  53. P2X7 receptor activity landscape in rat and human glioma cell lines
    Damian P. Matysniak, Natalia Nowak, Vira Chumak, Paweł Pomorski · 2020 · Acta Biochimica Polonica
  54. P2X7 receptors are involved in stress-related behaviours and antidepressant effect
    Ribeiro, D.E., Stanquini, L.A., Biojone, C., Casarotto, P.C., Elfving, B., Müller, H.K., Wegener, G., Joca, S.R.L. · 2019 · European Neuropsychopharmacology
  55. Evaluation of Placental Toxicity of Five Essential Oils and Their Potential Endocrine-Disrupting Effects
    Sophie Fouyet, Elodie Olivier, Pascale Leproux, Mélody Dutot, Patrice Rat · 2022 · Current Issues in Molecular Biology
  56. P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells
    Cheng Cheng, Jiaoyao Ma, Xiaoling Lu, Panpan Zhang, Xiaohan Wang, Luo Guo, Peifan Li, Ying Wei, Geng‐Lin Li, Xia Gao et al. · 2023 · Neurobiology of Disease
  57. The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy
    Divyeshz Thakku Sivakumar, Krishi Jain, Noura Alfehaid, Yitao Wang, Xinchen Teng, Wolfgang Fischer, Tobías Engel · 2024 · International Journal of Molecular Sciences
  58. Mapping COVID-19 functional sequelae: the perspective of nuclear medicine.
    Simone Cristina Soares Brandão, Júlia de Oliveira Xavier Ramos, Gustavo Freitas Alves de Arruda, Emmanuelle Tenório Albuquerque Madruga Godoi, Lara Cristiane Terra Ferreira Carreira, Rafael Willain Lopes, Gabriel Blacher Grossman, Ronaldo de Souza Leão Lima · 2020 · PubMed Central
  59. Novel Indications for Benzodiazepine Antagonist Flumazenil in GABA Mediated Pathological Conditions of the Central Nervous System
    Gary Kenneth Hulse, Erin A. Kelty, Sean D. Hood, Amanda F. Norman, Maria Basso, Albert Stuart Reece · 2015 · Current Pharmaceutical Design
  60. Editorial: P2X7 as Common Therapeutic Target in Brain Diseases
    Tobías Engel, Annette Nicke, Jan M. Deussing, Beáta Sperlágh, Miguel Dı́az-Hernández · 2021 · Frontiers in Molecular Neuroscience
  61. Beyond monoamines: II. Novel applications for PET imaging in psychiatric disorders
    Sarah K. Royse, Brian J. Lopresti, Chester A. Mathis, Savannah Tollefson, Rajesh Narendran · 2022 · Journal of Neurochemistry
  62. A-Raf and C-Raf differentially regulate mechanobiological response of osteoblasts to guide mechanical stress-induced differentiation
    Qi Zhang, Hiroyuki Matsui, Hisanori Horiuchi, Xing Liang, Keiichi Sasaki · 2016 · Biochemical and Biophysical Research Communications
  63. The role of polycyclic frameworks in modulating P2X7 receptor function
    Timothy B. Callis, Tristan A. Reekie, James O’Brien-Brown, Erick C.N. Wong, Eryn L. Werry, Nabiha Elias, William T. Jorgensen, John Tsanaktsidis, Louis M. Rendina, Michael Kassiou · 2017 · Tetrahedron
  64. Emerging roles of the P2X7 receptor in cancer pain
    Ping Wu, Yin Wang, Yansong Liu, Yan Liu, Guohua Zhou, Xiaoqi Wu, Qingping Wen · 2022 · Purinergic Signalling
  65. Identification of glia phenotype modulators based on select glial function regulatory signaling pathways
    Sun Hwa Lee, Kyoungho Suk · 2018 · Expert Opinion on Drug Discovery
  66. Exploring P2X receptor activity: A journey from cellular impact to electrophysiological profiling
    Calvin Dunker, Laura Vinnenberg, Andreas Isaak, Elif Karabatak, Petra Hundehege, Thomas Budde, Kazuhiro Murakami, Anna Junker · 2024 · Biochemical Pharmacology
  67. Purinergic modulation of major depressive disorder: Experimental findings, pathogenesis and therapeutic opportunities
    Xing-Ying Ren, Patrizia Rubini, Tobías Engel, Yong Tang, Péter Illés · 2025 · Pharmacological Research
  68. P2X7-dependent constitutive Interleukin-1β release from pyramidal neurons of the normal mouse hippocampus: Evidence for a role in maintenance of the innate seizure threshold
    Spandita Seouli Dutta, Antoaneta A. Andonova, Torsten Wöellert, Sandra J. Hewett, James A. Hewett · 2022 · Neurobiology of Disease
  69. Synthesis and biological evaluation of carboxamide and quinoline derivatives as P2X7R antagonists
    Qasim Shah, Zahid Hussain, Bilal Ahmad Khan, Kenneth A. Jacobson, Jamshed Iqbal · 2023 · Bioorganic Chemistry
  70. Association of Hypomorphic P2X7 Receptor Genotype With Age
    Juana María Sanz, Simonetta Falzoni, Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani, Francesco Di Virgilio · 2020 · Frontiers in Molecular Neuroscience
  71. PET Imaging of Neuroinflammation
    Aisling M. Chaney, Emily M. Deal, Isaac M. Jackson, Michelle Louise James · 2021 · Elsevier eBooks
  72. Cocktail Effect of Endocrine Disrupting Chemicals: Application to Chlorpyrifos in Lavender Essential Oils
    Sophie Fouyet, Elodie Olivier, Pascale Leproux, Sabrina Boutefnouchet, Mélody Dutot, Patrice Rat · 2022 · International Journal of Environmental Research and Public Health
  73. Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks
    Stefanie M. A. Willekens, Donatienne Van Weehaeghe, Philip Van Damme, Koen Van Laere · 2016 · European Journal of Nuclear Medicine and Molecular Imaging
  74. Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations
    Makiko Fujiwara, Kenshi Ohbori, Akihiro Ohishi, Kentaro Nishida, Yoshinobu Uozumi, Kazuki Nagasawa · 2017 · Biological and Pharmaceutical Bulletin
  75. Functional role of P2X7 purinergic receptor in cancer and cancer-related pain
    Yongsheng Xu, Jun Xiang, Sijian Lin · 2024 · Purinergic Signalling
  76. Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction
    Juan Sierra‐Marquez, Lena Schaller, Lukas Sassenbach, Antonio Ramírez-Fernández, Philipp Alt, Björn Rissiek, Béla Zimmer, Johann Schredelseker, Julia Hector, Tobias Stähler et al. · 2024 · Frontiers in Immunology
  77. Astrocytic P2X7 receptor regulates depressive-like behavioral reactions of mice in response to acute stressful stimulation
    Xin-Yi Cheng, Wen-Jing Ren, Xuan Li, Jan M. Deussing, Péter Illés, Yong Tang, Patrizia Rubini · 2024 · Purinergic Signalling
  78. The role of maternal infections in neurodevelopmental psychiatric disorders: focus on the P2X7/NLRP3/IL-1β signalling pathway
    Dorottya Szabó, Lilla Otrokocsi, Beáta Sperlágh · 2025 · Journal of Neuroinflammation
  79. Purinergic and extracellular vesicle signaling in alcohol-induced blood–brain barrier breakdown and neuroimmune activation
    Namdev S. Togre, Priyanka S. Bhoj, Naveen Kumar Mekala, Rebecca Hancock, Jayshil Trivedi, Yuri Persidsky · 2025 · Brain Behavior and Immunity
  80. Scrutinizing the Therapeutic Promise of Purinergic Receptors Targeting Depression
    Priyanshi Sikka, Tapan Behl, Parteek Chandel, Aayush Sehgal, Sukhbir Singh, Hafiz Antar Makeen, Mohammed Albratty, Hassan A. Alhazmi, Abdulkarim M. Meraya · 2022 · Neurotoxicity Research
  81. Role of the P2 × 7 receptor in neurodegenerative diseases and its pharmacological properties
    Ziyan Hu, Yifan Luo, Jinxi Zhu, Danling Jiang, Zhenzhong Luo, Lidong Wu, Li Jin, Shengliang Peng, Jialing Hu · 2023 · Cell & Bioscience
  82. Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus
    Muhammad Tahir Khan, Juan Liu, Jana Nerlich, Yong Tang, Heike Franke, Péter Illés · 2018 · Neuropharmacology
  83. Diabetes-induced damage of gastric nitric oxide neurons mediated by P2X7R in diabetic mice
    Chunmei Zhang, Xu Huang, Hongli Lu, Xiangmin Meng, Nina Song, Lu Chen, Youngchul Kim, Jie Chen, Wen‐Xie Xu · 2019 · European Journal of Pharmacology
  84. The role of vitamin D and P2X7R in multiple sclerosis
    Veronica Tsin Fong Voo, Terence John O'Brien, Helmut Butzkueven, Mastura Monif · 2019 · Journal of Neuroimmunology
  85. Antagonistic Roles of P2X7 and P2Y2 Receptors in Neurodegenerative Diseases
    Talita Glaser, Ágatha Oliveira‐Giacomelli, Lyvia Lintzmaier Petiz, Deidiane Elisa Ribeiro, Roberta Andrejew, Henning Ulrich · 2021 · Frontiers in Pharmacology
  86. Free-labelled fluorescent method for ATP detection assisted by T4 DNA ligase
    Hongyun Huang, Shui Fu, Yan Huang, Jianniao Tian, Yanchun Zhao, Shulin Zhao · 2017 · Analytical Methods
  87. P2X7 and A2A receptor endogenous activation protects against neuronal death caused by CoCl2‐induced photoreceptor toxicity in the zebrafish retina
    Matías P. Medrano, Antonella Pisera-Fuster, Ramón Bernabeu, María Paula Faillace · 2020 · The Journal of Comparative Neurology
  88. Role of purinergic receptors in cardiac sympathetic nerve injury in diabetes mellitus.
    Qi-Xing Hu, Gui-Lin Li · 2022 · Neuropharmacology
  89. Embers of the Past: Early Childhood Traumas Interact with Variation in P2RX7 Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk
    Zsüliet Kristóf, Zsófia Gál, Dóra Török, Nóra Eszlári, Sára Sütöri, Beáta Sperlágh, Ian Muir Anderson, J.F.W. Deakin, György Bagdy, Gabriella Juhász et al. · 2024 · International Journal of Molecular Sciences
  90. Targeting calciumopathy for neuroprotection: focus on calcium channels Cav1, Orai1 and P2X7
    Myriam Torres-Rico, Virginia García-Calvo, Adrián Gironda-Martínez, Jorge Pascual-Guerra, Antonio G. Garcı́a, Victoria Maneu · 2024 · Cell Calcium
  91. NADPH acts as an endogenous P2X7 receptor modulator to gate neuroinflammatory responses of microglia
    Yu-jie Mou, Feng-min Li, Jun-tong Lou, Hai‐Yue Tu, Yi Zhun Zhu, Rui Sheng, Zhong-ling Zhang, Yuzheng Zhao, Fuhai Ji, Junchao Wu et al. · 2025 · Acta Pharmacologica Sinica
  92. Effects of probenecid and brilliant blue G on rat enteric glial cells following intestinal ischemia and reperfusion
    Cristina Eusébio Mendes, Kelly Palombit, Thaira Thalita Alves Pereira, Henrique Inhauser Riceti Magalhães, Marcos Antônio Ferreira Caetano, Patrícia Castelucci · 2022 · Acta Histochemica
  93. Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes
    Jaideep Kesavan, Orla Watters, Laura de Diego-García, Aida Menéndez Méndez, Mariana Alves, Klaus Dinkel, Michael Hamacher, Jochen H.M. Prehn, David Clifford Henshall, Tobías Engel · 2023 · Purinergic Signalling
  94. Purinergic modulation of frog electroretinographic responses: The role of the ionotropic receptor P2X7
    Petia Kupenova, E. Popova, Lily Alexandrova Vitanova · 2017 · Visual Neuroscience
  95. P2X7 receptors and pannexin1 hemichannels shape presynaptic transmission
    Nathalia Vitureira, Alberto Rafael, Verónica Abudara · 2023 · Purinergic Signalling
  96. Focus on P2X7R in microglia: its mechanism of action and therapeutic prospects in various neuropathic pain models
    Kai Zhang, Rui Ran, Chengjun Zhang, Linna Wang, Haihong Zhang · 2025 · Frontiers in Pharmacology
  97. Targeting the P2X7 receptor signaling pathway: Unlocking therapeutic strategies for autism spectrum disorder
    Chetana G. Ahire, Ginpreet Kaur · 2025 · Brain Behavior & Immunity - Health
  98. Age-Dependent Activation of Purinergic Transmission Contributes to the Development of Epileptogenesis in ADSHE Model Rats
    Kouji Fukuyama, Eishi Motomura, Motohiro Okada · 2024 · Biomolecules
  99. CLADIN- CLADribine and INnate immune response in multiple sclerosis – A phase IV prospective study
    Mastura Monif, Richard P. Sequeira, Andrea M. Muscat, Sian Stuckey, Paul Gerard Sanfilippo, Viet Bui Minh, Naomi Loftus, Veronica Tsin Fong Voo, Katherine Fazzolari, Melinda Moss et al. · 2024 · Clinical Immunology
  100. P2X7 receptors modulate acquisition of cue fear extinction and contextual background memory generalization in male mice
    Luana Barreto Domingos, Antonio Furtado da Silva-Júnior, Cassiano R.A.F. Diniz, Jéssica Rosa, Ana Luisa B. Terzian, Leonardo B.M. Resstel · 2024 · Neuropharmacology