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Revisiting Astrocytic Roles in Methylmercury Intoxication

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Human Oligodendrocytes and Myelin In Vitro to Evaluate Developmental Neurotoxicity

Chesnut, M., Härtung, T., Högberg, H. T., & Pamies, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157929 · Cited by 29 · see citing works

Simple and Inexpensive Paper-Based Astrocyte Co-culture to Improve Survival of Low-Density Neuronal Networks

Aebersold, M. J., Thompson‐Steckel, G., Joutang, A., Schneider, M., Burchert, C., Forró, C., Weydert, S., Han, H., & Vörös, J. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00094 · Cited by 23 · see citing works

Mass Generation, Neuron Labeling, and 3D Imaging of Minibrains

Govindan, S., Batti, L., Osterop, S. F., Stoppini, L., & Roux, A. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.582650 · Cited by 25 · see citing works

Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq

de Leeuw, V. C., van Oostrom, C. T. M., Wackers, P. F. K., Pennings, J. L. A., Hodemaekers, H. M., Piersma, A. H., & Hessel, E. V. S. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.135298 · Cited by 23 · see citing works

Human-Based New Approach Methodologies in Developmental Toxicity Testing: A Step Ahead from the State of the Art with a Feto–Placental Organ-on-Chip Platform

Luconi, M., Sogorb, M. A., Markert, U. R., Benfenati, E., May, T., Wolbank, S., Roncaglioni, A., Schmidt, A., Straccia, M., & Tait, S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192315828 · Cited by 23 · see citing works

Studying Heterotypic Cell–Cell Interactions in the Human Brain Using Pluripotent Stem Cell Models for Neurodegeneration

Song, L., Yan, Y., Marzano, M., & Li, Y. (2019) · Cells · doi:10.3390/cells8040299 · Cited by 21 · see citing works

Human Pluripotent Stem Cells as Tools for Predicting Developmental Neural Toxicity of Chemicals: Strategies, Applications, and Challenges

Liang, S., Yin, N., & Faiola, F. (2019) · Stem Cells and Development · doi:10.1089/scd.2019.0007 · Cited by 21 · see citing works

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

Chesnut, M., Munoz-Arcos, L. S., Harris, G., Freeman, D. M., Gama, L., Pardo, C. A., & Pamies, D. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00223 · Cited by 20 · see citing works

Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity

Acharya, P., Shrestha, S., Joshi, P., Choi, N. Y., Lekkala, V. K. R., Kang, S., Ni, G., & Lee, M. (2024) · Biofabrication · doi:10.1088/1758-5090/ad867e · Cited by 14 · see citing works

An efficient neuron-astrocyte differentiation protocol from human embryonic stem cell-derived neural progenitors to assess chemical-induced developmental neurotoxicity

de Leeuw, V. C., van Oostrom, C. T. M., Westerink, R. H. S., Piersma, A. H., Heusinkveld, H. J., & Hessel, E. V. S. (2020) · Reproductive Toxicology · doi:10.1016/j.reprotox.2020.09.003 · Cited by 13 · see citing works

Generation of a Triple-Transgenic Zebrafish Line for Assessment of Developmental Neurotoxicity during Neuronal Differentiation

Koiwa, J., Shiromizu, T., Adachi, Y., Ikejiri, M., Nakatani, K., Tanaka, T., & Nishimura, Y. (2019) · Pharmaceuticals · doi:10.3390/ph12040145 · Cited by 11 · see citing works

Andrographolide induce human embryonic stem cell apoptosis by oxidative stress response

Huang, H., Cao, H., Xing, C., Hua, Y., Zhang, M., & Jin, L. (2019) · Molecular & Cellular Toxicology · doi:10.1007/s13273-019-0024-x · Cited by 10 · see citing works

An engineered mouse embryonic stem cell model with survivin as a molecular marker and EGFP as the reporter for high throughput screening of embryotoxic chemicals in vitro

Zang, R., Xin, X., Zhang, F., Li, D., & Yang, S. (2019) · Biotechnology and Bioengineering · doi:10.1002/bit.26977 · Cited by 7 · see citing works

Neural organoids as advanced tools for neurotoxicity modeling

Majumder, J., & Murphy, W. L. (2025) · Current Research in Toxicology · doi:10.1016/j.crtox.2025.100249 · Cited by 7 · see citing works

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity_suppl

Bal‐Price, A. (2018) · ALTEX · doi:10.14573/altex.1712081s · Cited by 4 · see citing works

Modelling the human brain in vitro : biofabrication approaches for neural tissue engineering

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Alternative methods to animal experimentation for testing developmental toxicity

Pamies, D., Estevan, C., Vilanova, E., & Sogorb, M. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89773-0.00007-2 · Cited by 2 · see citing works

Neurotoxicology and Disease Modelling

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The Future of Neurotoxicology: A Neuroelectrophysiological Viewpoint

Herr, D. W. (2021) · Frontiers in Toxicology · doi:10.3389/ftox.2021.729788 · Cited by 1 · see citing works

Enhanced electrophysiological activity and neurotoxicity screening of environmental chemicals using 3D neurons from human neural precursor cells purified with PSA-NCAM

Choi, M., Park, S., Kim, S., Jegal, H., Lee, H., Han, H., Yoon, S., Kim, S. K., & Oh, J. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116516 · Cited by 1 · see citing works

Human neural stem cells in developmental neurotoxicology: Current scenario and future prospects

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Central Nervous System Toxicity Biomarkers

Costa, L. G. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814655-2.00010-4 · Cited by 1 · see citing works

Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leading to impairment of learning and memory

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Human Cerebral Organoids in Pillar/Perfusion Plates for Modeling Neurodevelopmental Disorders

Acharya, P. (2024) · doi:10.12794/metadc2332637

Utilization of human stem cells to examine neurotoxic impacts on differentiation

de Leeuw, V. C., & Hessel, E. V. S. (2024) · Advances in neurotoxicology · doi:10.1016/bs.ant.2024.08.001

Consolidated and next-generation models in DDS nanotoxicology assessment: Where do we stand

D’Intino, E., Stacchini, F. R., Fabiano, M. G., Marianecci, C., & Carafa, M. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108598

Review of in vitro approaches for assessing the toxicity of chemical stressors across diverse physiological systems

Mukherjee, R., Mudalige, C. P., Khan, A. H., Gonzalez-Acosta, M. F., Hong, M. S., & Desforges, J.-P. W. (2026) · Toxicological Sciences · doi:10.1093/toxsci/kfag097

Protein-repellent superhydrophobic aluminum mesh biointerfaces direct topography-guided neural stem cell spheroid formation

Jun, I., Kang, J. K., Park, H., Jang, G., Moon, D., Kim, Y. J., & Gwak, S. (2026) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2026.116280

Human neural stem cell culture and other in vitro model for prediction of embryotoxicity and neurotoxicity

Al-Rubai, A.-J. F. (2016) · Nottingham ePrints (University of Nottingham)

Novel scalable 3D cell based model for in vitro neurotoxicity testing: Combining human differentiated neurospheres with gene expression and functional endpoints

Terrasso, A. P., Pinto, C., Serra, M., Filipe, A., Almeida, S., Ferreira, A. L. A., Pedroso, P., Brito, C., & Alves, P. M. (2015) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.12.011 · Cited by 27 · see citing works

A human pluripotent carcinoma stem cell‐based model for in vitro developmental neurotoxicity testing: Effects of methylmercury, lead and aluminum evaluated by gene expression studies

Laurenza, I., Pallocca, G., Mennecozzi, M., Scelfo, B., Pamies, D., & Bal‐Price, A. (2013) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2013.03.002 · Cited by 42 · see citing works

Use of human pluripotent stem cells and their progeny to develop in vitro models for neurotoxicity testing

Hölting, L. (2015)

Human pluripotent stem cell-derived neural tissue models for neurotoxicity screening

Schwartz, M. P., Zhonggang, H., Propson, N. E., Zhang, J., Pellett, S., Eric, J. S., James, T., & Murphy, W. L. (2016) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/conf.fbioe.2016.01.00877