The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Models for oral uptake of nanoparticles in consumer products
Open accessAbstract
Presently, many consumer products contain nano-sized materials (NMs) to improve material properties, product quality and ease of use. NMs in food additives and in cosmetic articles (e.g., tooth paste) may be taken up by the oral route. As adverse effects of environmental nanoparticles, like ultrafine particles, have been reported, consumers worry about potential risks when using products containing NMs. The review focuses on metal and metal oxide NMs as common additives in tooth paste and in food industry and exposure by the oral route. Testing of NMs for oral exposure is very complex because differences in the diet, in mucus secretion and composition, in pH, in gastrointestinal transit time and in gastrointestinal flora influence NM uptake. Acellular (mucus, saliva) and epithelial layer of the orogastrointestinal barrier are described. Expected exposure doses, interaction of the NMs with mucus and permeation through the epithelium as well as in vivo data are mentioned. The role of in vitro models for the study of parameters relevant for ingested NMs is discussed.
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Toxicity of Silver Nanoparticles to Chlamydomonas reinhardtii
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Metadata
- Authors
- Fröhlich, E., & Roblegg, E.
- Venue
- Toxicology
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 291
- Issue
- 1-3
- Pages
- 10-17
- ISSN
- 0300-483X (ISSN-L)
- OpenAlex
- W2007730359
- Cited by
- 295
- References
- 109
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
