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How relevant are flavonoids as antioxidants in plants?

Hernández, Iker, Alegre, Leonor, Van Breusegem, Frank, Munné-Bosch, Sergi·2009·Trends in Plant Science

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Research works printed but not linked: 55

  1. Williams, 2004, Anthocyanins and other flavonoids, Nat. Prod. Rep., 21, 539, 10.1039/b311404j · DOI · Paper page
  2. Butelli, 2008, Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors, Nat. Biotechnol., 26, 1301, 10.1038/nbt.1506 · DOI · Paper page
  3. Winkel-Shirley, 2001, It takes a garden. How work on diverse plant species has contributed to an understanding of flavonoid metabolism, Plant Physiol., 127, 1399, 10.1104/pp.010675 · DOI · Paper page
  4. Winkel-Shirley, 2002, Biosynthesis of flavonoids and effects of stress, Curr. Opin. Plant Biol., 5, 218, 10.1016/S1369-5266(02)00256-X · DOI · Paper page
  5. Dixon, 1995, Stress induced phenylpropanoid metabolism, Plant Cell, 7, 1085, 10.2307/3870059 · DOI · Paper page
  6. Asada, 2006, Production and scavenging of reactive oxygen species in chloroplasts and their functions, Plant Physiol., 141, 391, 10.1104/pp.106.082040 · DOI · Paper page
  7. Van Breusegem, 2006, Reactive oxygen species in plant cell death, Plant Physiol., 141, 384, 10.1104/pp.106.078295 · DOI · Paper page
  8. Mittler, 2004, The reactive oxygen gene network in plants, Trends Plant Sci., 9, 490, 10.1016/j.tplants.2004.08.009 · DOI · Paper page
  9. Rice-Evans, 1997, Antioxidant properties of phenolic compounds, Trends Plant Sci., 2, 152, 10.1016/S1360-1385(97)01018-2 · DOI · Paper page
  10. Pourcel, 2006, Flavonoid oxidation in plants: from biochemical properties to physiological functions, Trends Plant Sci., 12, 29, 10.1016/j.tplants.2006.11.006 · DOI · Paper page
  11. Bayrakçeken, 2003, High resolution electronic absorption spectra of anisole and phenoxyl radical, Spectrochim. Acta [A], 59, 135, 10.1016/S1386-1425(02)00143-9 · doi:10.1016/s1386-1425(02)00143-9
  12. Hernández, 2006, Enhanced oxidation of flavan-3-ols and proanthocyanidin accumulation in water-stressed tea plants, Phytochemistry, 67, 1120, 10.1016/j.phytochem.2006.04.002 · DOI
  13. Awad, 2001, Structure–activity study on the quinone/quinone methide chemistry of flavonoids, Chem. Res. Toxicol., 14, 398, 10.1021/tx000216e · DOI · Paper page
  14. Awad, 2002, The regioselectivity of glutathione adduct formation with flavonoid quinone/quinone methides is pH-dependent, Chem. Res. Toxicol., 15, 343, 10.1021/tx010132l · DOI
  15. Torres, 2005, Conjugation of catechins with cysteine generates antioxidant compounds with enhanced neuroprotective activity, Phytochemistry, 66, 2032, 10.1016/j.phytochem.2004.12.003 · DOI
  16. Kanakis, 2005, DNA interaction with naturally occurring antioxidant flavonoids quercetin, kaempferol, and delphinidin, J. Biomol. Struct. Dyn., 22, 719, 10.1080/07391102.2005.10507038 · doi:10.1080/07391102.2005.10507038
  17. Martinoia, 2007, Vacuolar transporters and their essential role in plant metabolism, J. Exp. Bot., 58, 83, 10.1093/jxb/erl183 · DOI · Paper page
  18. Dixon, 2005, Proanthocyanidins – a final frontier in flavonoid research?, New Phytol., 165, 9, 10.1111/j.1469-8137.2004.01217.x · DOI · Paper page
  19. Hernández, 2004, Drought-induced changes in flavonoids and other low molecular weight antioxidants in Cistus clusii grown under Mediterranean field conditions, Tree Physiol., 24, 1303, 10.1093/treephys/24.11.1303 · DOI · Paper page
  20. Kirakosyan, 2003, Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (hawthorn) subjected to drought and cold stress, J. Agric. Food Chem., 51, 3973, 10.1021/jf030096r · doi:10.1021/jf030096r
  21. Hrazdina, 1985, Metabolic pathways as enzyme complexes: evidence for the synthesis of phenylpropanoids and flavonoids on membrane associated enzyme complexes, Arch. Biochem. Biophys., 237, 88, 10.1016/0003-9861(85)90257-7 · DOI
  22. Grotewold, 2008, Trafficking and sequestration of anthocyanins, Nat. Prod. Comm., 3, 1251
  23. Debeaujon, 2001, The TRANSPARENT TESTA12 gene of Arabidopsis encodes a multidrug secondary transporter-like protein required for flavonoid sequestration in vacuoles of the seed coat endothelium, Plant Cell, 13, 853, 10.1105/tpc.13.4.853 · DOI · Paper page
  24. Erlejman, 2004, The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects, Free Radic. Res., 38, 1311, 10.1080/10715760400016105 · DOI · Paper page
  25. Caturla, 2003, The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes, Free Radic. Biol. Med., 34, 648, 10.1016/S0891-5849(02)01366-7 · DOI · Paper page
  26. Saffari, 2004, Green tea metabolite EGCG protects membranes against oxidative damage in vitro, Life Sci., 74, 1513, 10.1016/j.lfs.2003.08.019 · DOI
  27. Galati, 2002, Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics, Toxicology, 177, 91, 10.1016/S0300-483X(02)00198-1 · DOI · Paper page
  28. Mehler, 1951, Studies on reactions of illuminated chloroplasts. I. Mechanism of the reduction of oxygen and other Hill reagents, Arch. Biochem. Biophys., 33, 65, 10.1016/0003-9861(51)90082-3 · DOI · Paper page
  29. Saunders, 1976, The distribution of flavonoids in chloroplasts of twenty five species of vascular plants, Phytochemistry, 15, 809, 10.1016/S0031-9422(00)94452-2 · doi:10.1016/s0031-9422(00)94452-2
  30. Zaprometov, 2003, Chloroplasts isolated from kidney bean leaves are capable of phenolic compound biosynthesis, Russ. J. Plant Physiol., 50, 623, 10.1023/A:1025683922953 · doi:10.1023/a:1025683922953
  31. Takahama, 1983, Redox reactions between kaempferol and illuminated chloroplasts, Plant Physiol., 71, 598, 10.1104/pp.71.3.598 · doi:10.1104/pp.71.3.598
  32. Takahama, 1984, Hydrogen peroxide-dependent oxidation of flavonols by intact spinach chloroplasts, Plant Physiol., 74, 852, 10.1104/pp.74.4.852 · DOI
  33. Vanderauwera, 2005, Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis, Plant Physiol., 139, 806, 10.1104/pp.105.065896 · DOI · Paper page
  34. Agati, 2007, Chloroplast-located flavonoids can scavenge singlet oxygen, New Phytol., 174, 77, 10.1111/j.1469-8137.2007.01986.x · DOI · Paper page
  35. Bienert, 2006, Membrane transport of hydrogen peroxide, Biochim. Biophys. Acta, 1758, 994, 10.1016/j.bbamem.2006.02.015 · DOI · Paper page
  36. Gould, 2002, Do anthocyanins function as antioxidants in leaves? Imaging of H2O2 in red and green leaves after mechanical injury, Plant Cell Environ., 25, 1261, 10.1046/j.1365-3040.2002.00905.x · DOI · Paper page
  37. Feucht, 2004, Flavanol binding of nuclei from tree species, Plant Cell Rep., 22, 430, 10.1007/s00299-003-0705-7 · DOI
  38. Saslowsky, 2005, Nuclear localization of flavonoid enzymes in Arabidopsis, J. Biol. Chem., 280, 23735, 10.1074/jbc.M413506200 · DOI · Paper page
  39. Melidou, 2005, Protection against nuclear DNA damage offered by flavonoids in cells exposed to hydrogen peroxide: the role of iron chelation, Free Radic. Biol. Med., 39, 1591, 10.1016/j.freeradbiomed.2005.08.009 · DOI · Paper page
  40. Polster, 2006, Flavonoids in plant nuclei: detection by laser microdissection and pressure catapulting (LMPC), in vivo staining, and UV-visible spectroscopic titration, Physiol. Plant., 128, 163, 10.1111/j.1399-3054.2006.00721.x · DOI
  41. Polster, 2003, Are histones the targets for flavan-3-ols (catechins) in nuclei?, Biol. Chem., 384, 997, 10.1515/BC.2003.112 · doi:10.1515/bc.2003.112
  42. Constantinou, 1995, Flavonoids as DNA topoisomerase antagonists and poisons: structure–activity relationships, J. Nat. Prod., 58, 217, 10.1021/np50116a009 · DOI · Paper page
  43. Tomás-Barberán, 1988, Antifungal epicuticular methylated flavonoids from Helichrysum nitens, Phytochemistry, 27, 753, 10.1016/0031-9422(88)84087-1 · doi:10.1016/0031-9422(88)84087-1
  44. Alcerito, 2002, Foliar epicuticular wax of Arrabidaea brachypoda: flavonoids and antifungal activity, Biochem. Syst. Ecol., 30, 677, 10.1016/S0305-1978(01)00149-1 · DOI
  45. Asada, 1999, The water–water cycle in chloroplasts: scavenging of active oxygens and dissipation of excess photons, Annu. Rev. Plant Physiol. Plant Mol. Biol., 50, 601, 10.1146/annurev.arplant.50.1.601 · DOI · Paper page
  46. Munné-Bosch, 2002, The function of tocopherols and tocotrienols in plants, Crit. Rev. Plant Sci., 21, 31, 10.1080/0735-260291044179 · doi:10.1080/0735-260291044179 · Paper page
  47. Yamasaki, 1997, Flavonoid-peroxidase reaction as a detoxification mechanism of plant cells against H2O2, Plant Physiol., 115, 1405, 10.1104/pp.115.4.1405 · DOI · Paper page
  48. Pérez, 2002, Ascorbic acid and flavonoid-peroxidase reaction as a detoxifying system of H2O2 in grapevine leaves, Phytochemistry, 60, 573, 10.1016/S0031-9422(02)00146-2 · doi:10.1016/s0031-9422(02)00146-2
  49. Yamasaki, 1998, EPR detection of phytophenoxyl radicals stabilized by zinc ions: evidence for the redox coupling of plant phenolics with ascorbate in the H2O2-peroxidase system, FEBS Lett., 422, 377, 10.1016/S0014-5793(98)00048-9 · DOI
  50. Sakihama, 2000, Reduction of phenoxyl radicals mediated by monodehydroascorbate reductase, Biochem. Biophys. Res. Commun., 279, 949, 10.1006/bbrc.2000.4053 · DOI
  51. Munné-Bosch, 2002, Interplay between ascorbic acid and lipophilic antioxidant defences in chloroplasts of water-stressed Arabidopsis plants, FEBS Lett., 524, 145, 10.1016/S0014-5793(02)03041-7 · DOI
  52. Caretto, 2002, Ascorbate and glutathione metabolism in two sunflower cell lines of differing α-tocopherol biosynthetic capability, Plant Physiol. Biochem., 40, 509, 10.1016/S0981-9428(02)01419-5 · DOI
  53. Grotewold, 2005, Plant metabolic diversity: a regulatory perspective, Trends Plant Sci., 10, 57, 10.1016/j.tplants.2004.12.009 · DOI
  54. Mackova, 2006, Distribution of isoflavonoids in non-leguminous taxa – an update, Phytochemistry, 67, 849, 10.1016/j.phytochem.2006.01.020 · DOI
  55. Prior, 2005, Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements, J. Agric. Food Chem., 53, 4290, 10.1021/jf0502698 · DOI · Paper page

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Metadata

Authors
Hernández, I., Alegre, L., Van Breusegem, F., & Munné-Bosch, S.
Venue
Trends in Plant Science
Publisher
Elsevier BV
Published
2009-03
Volume
14
Issue
3
Pages
125-132
ISSN
1360-1385 (ISSN-L)
OpenAlex
W2084640360
Cited by
703
References
1
FWCI
4.47
Type
journal article
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)

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Hernández, I., Alegre, L., Van Breusegem, F., & Munné-Bosch, S. (2009). How relevant are flavonoids as antioxidants in plants? Trends in Plant Science. https://doi.org/10.1016/j.tplants.2008.12.003

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