Analytical problems and the need for sample preparation in the determination of pharmaceuticals and their metabolites in aqueous environmental matrices
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Sample preparation is the most challenging step regarding the green parameters of a method and consumes large amounts of toxic conventional solvents.
“Upon considering the impact of analytical procedures to the environment, sample preparation was found to be the most challenging step regarding the green parameters of a method.It consumes large amount of toxic conventional solvents [3].”
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El-Deen, A. K., & Shimizu, K. (2021) · Molecules · doi:10.3390/molecules26237406 · Cited by 58 · see citing works
“It consumes large amount of toxic conventional solvents [3].”
Background
- Authors
- Kostopoulou, M., & Nikolaou, A.
- Affiliations
- University of the Aegean (GR)
- Corresponding author
- Nikolaou, Anastasia
- ORCID
- Nikolaou, Anastasia
- Venue
- TrAC Trends in Analytical Chemistry
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 27
- Issue
- 11
- Pages
- 1023-1035
- ISSN
- 0165-9936 (ISSN-L)
- OpenAlex
- W1976910059
- Cited by
- 83
- References
- 68
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 4 · 2022: 4 · 2021: 6 · 2020: 2 · 2018: 5 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 10 · 2013: 5 · 2012: 12
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- TrAC Trends in Analytical Chemistry (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Life Sciences › Agricultural and Biological Sciences › Food Science › Pesticide Residue Analysis and Safety
- Keywords
- pharmaceuticals, drug metabolites, aquatic environment, sample preparation, trace analysis, environmental pollutants, water analysis, gas chromatography-mass spectrometry, LC-MS
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