Cited by 227Influenza Virus Research StudiesEvolution and Genetic DynamicsRespiratory viral infections research

The DOI matches its Crossref record; 47 of the 48 references it cites were found in a registry or an index.

Vaccination and antigenic drift in influenza

Open access

Boni, Maciej F.·2008·Vaccine

DOI 10.1016/j.vaccine.2008.04.011PMC PMC2603026

Open this paper in CoChat — free account

Abstract

The relationship between influenza antigenic drift and vaccination lies at the intersection of evolutionary biology and public health, and it must be viewed and analyzed in both contexts simultaneously. In this paper, 1 review what is known about the effects of antigenic drift on vaccination and the effects of vaccination on antigenic drift, and I suggest some simple ways to detect the presence of antigenic drift in seasonal influenza data. If antigenic drift occurs on the time scale of a single influenza season, it may be associated with the presence of herd immunity at the beginning of the season and may indicate a need to monitor for vaccine updates at the end of the season. The relationship between antigenic drift and vaccination must also be viewed in the context of the global circulation of influenza strains and the seeding of local and regional epidemics. In the data sets I consider--from New Zealand, New York, and France--antigenic drift can be statistically detected during some seasons, and seeding of epidemics appears to be endogenous sometimes and exogenous at other times. Improved detection of short-term antigenic drift and epidemic seeding would significantly benefit influenza monitoring efforts and vaccine selection.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.vaccine.2008.04.011

Cites

47 of 47 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Evolution and ecology of influenza A viruses
Webster, R. G., Bean, W. J., Gorman, O. T., Chambers, T. M., & Kawaoka, Y. (1992) · Microbiological Reviews · doi:10.1128/mr.56.1.152-179.1992 · Cited by 4,739
Mapping the Antigenic and Genetic Evolution of Influenza Virus
Smith, D. J., Lapedes, A. S., de Jong, J. C., Bestebroer, T. M., Rimmelzwaan, G. F., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2004) · Science · doi:10.1126/science.1097211 · Cited by 1,868
Unifying the Epidemiological and Evolutionary Dynamics of Pathogens
Grenfell, B. T., Pybus, O. G., Gog, J. R., Wood, J. L. N., Daly, J. M., MUMFORD, J. A., & Holmes, E. C. (2004) · Science · doi:10.1126/science.1090727 · Cited by 1,370
Herd Immunity: History, Theory, Practice
Fine, P. (1993) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036121 · Cited by 906
Global Epidemiology of Influenza: Past and Present
Cox, N. J., & Subbarao, K. (2000) · Annual Review of Medicine · doi:10.1146/annurev.med.51.1.407 · Cited by 838
Synchrony, Waves, and Spatial Hierarchies in the Spread of Influenza
Viboud, C. G., Bjørnstad, O. N., Smith, D. L., Simonsen, L., Miller, M. A., & Grenfell, B. T. (2006) · Science · doi:10.1126/science.1125237 · Cited by 832
The theory of gene frequencies
Wright, S. (1969) · University of Chicago Press eBooks · Cited by 755
Ecological and immunological determinants of influenza evolution.
Ferguson, N. M., Galvani, A. P., & Bush, R. M. (2003) · Nature · doi:10.1038/nature01509 · Cited by 746
Structural Basis of Immune Recognition of Influenza Virus Hemagglutinin
Wilson, I. A., & Cox, N. J. (1990) · Annual Review of Immunology · doi:10.1146/annurev.iy.08.040190.003513 · Cited by 571
The annual production cycle for influenza vaccine
Gerdil, C. (2003) · Vaccine · doi:10.1016/s0264-410x(03)00071-9 · Cited by 529

Show all 48 references

Sorted by citations

mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Chaudhary, N., Weissman, D., & Whitehead, K. A. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00283-5 · Cited by 1,555
An Exact Nonparametric Method for Inferring Mosaic Structure in Sequence Triplets
Boni, M. F., Posada, D., & Feldman, M. W. (2007) · Genetics · doi:10.1534/genetics.106.068874 · Cited by 765
Self-citation
Exploitation of glycosylation in enveloped virus pathobiology
Watanabe, Y., Bowden, T. A., Wilson, I. A., & Crispin, M. (2019) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2019.05.012 · Cited by 489
Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus
Pu, J., Wang, S., Yin, Y., Zhang, G., Carter, R. A., Wang, J., Xu, G., Sun, H., Wang, M., Wen, C., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1422456112 · Cited by 371
Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition
Kwon, P. S., Ren, S., Kwon, S., Kizer, M. E., Kuo, L., Xie, M., Zhu, D., Zhou, F., Zhang, F., Kim, D., et al. (2019) · Nature Chemistry · doi:10.1038/s41557-019-0369-8 · Cited by 317
Nanoparticle-Based Vaccines Against Respiratory Viruses
Soultan, A. H., Gauthier, L., Arpin, D., Bourgault, S., & Archambault, D. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00022 · Cited by 304
Viral shape-shifting: norovirus evasion of the human immune system
Donaldson, E., Lindesmith, L. C., LoBue, A. D., & Baric, R. S. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2296 · Cited by 276
2009 H1N1 Influenza
Sullivan, S. J., Jacobson, R. M., Dowdle, W. R., & Poland, G. A. (2009) · Mayo Clinic Proceedings · doi:10.4065/mcp.2009.0588 · Cited by 228
An Overview of Influenza Viruses and Vaccines
Nuwarda, R. F., Alharbi, A. A., & Kayser, V. (2021) · Vaccines · doi:10.3390/vaccines9091032 · Cited by 201
The Evolution and Biology of SARS-CoV-2 VariantsPreprint
Telenti, A., Hodcroft, E. B., & Robertson, D. L. (2022) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041390 · Cited by 191
Microbial antigenic variation mediated by homologous DNA recombination
Vink, C., Rudenko, G., & Seifert, H. S. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00321.x · Cited by 136
Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant strains
Rella, S. A., Kulikova, Y. A., Dermitzakis, E. T., & Kondrashov, F. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-95025-3 · Cited by 139
The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction
Jackson, A. P., Otto, T. D., Darby, A. C., Ramaprasad, A., Xia, D., Echaide, I. E., Farber, M. D., Gahlot, S., Gamble, J. A., Gupta, D. K., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku322 · Cited by 130
The Double-Edged Sword: How Evolution Can Make or Break a Live-Attenuated Virus Vaccine
Hanley, K. A. (2011) · Evolution Education and Outreach · doi:10.1007/s12052-011-0365-y · Cited by 125
Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
Du, X., Dong, L., Lan, Y., Peng, Y., Wu, A., Zhang, Y., Huang, W., Wang, D., Wang, M., Guo, Y., et al. (2012) · Nature Communications · doi:10.1038/ncomms1710 · Cited by 115
Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method
Li, X.-B., Wang, S., Xu, W., Wang, R., & Chou, K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028111 · Cited by 107
Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity
Budimir, N., Varga, S. M., Badovinac, V. P., & Harty, J. T. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.08.073 · Cited by 104
Variable seasonal influenza vaccine effectiveness across geographical regions, age groups and levels of vaccine antigenic similarity with circulating virus strains: A systematic review and meta-analysis of the evidence from test-negative design studies after the 2009/10 influenza pandemic
Okoli, G. N., Racovitan, F., Abdulwahid, T., Righolt, C. H., & Mahmud, S. M. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.01.032 · Cited by 87
A Systematic Review of Recent Advances in Equine Influenza Vaccination
Paillot, R. (2014) · Vaccines · doi:10.3390/vaccines2040797 · Cited by 90
The local stability of a modified multi-strain SIR model for emerging viral strains
Fudolig, M. A., & Howard, R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243408 · Cited by 89
RETRACTED: Two Birds with One Stone? Possible Dual-Targeting H1N1 Inhibitors from Traditional Chinese Medicine
Chang, S., Huang, H.-J., & Chen, C. Y. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002315 · Cited by 83
Retracted
Guidelines for Identifying Homologous Recombination Events in Influenza A Virus
Boni, M. F., de Jong, M. D., van Doorn, H. R., & Holmes, E. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010434 · Cited by 88
Self-citation
Perspectives on influenza evolution and the role of research
Forrest, H. L., & Webster, R. G. (2010) · Animal Health Research Reviews · doi:10.1017/s1466252310000071 · Cited by 90
Genetic analysis and antigenic characterization of swine origin influenza viruses isolated from humans in the United States, 1990–2010
Shu, B., Garten, R. J., Emery, S. L., Balish, A. L., Cooper, L. A., Sessions, W. M., Deyde, V., Smith, C., Berman, L., Klimov, A. I., et al. (2011) · Virology · doi:10.1016/j.virol.2011.10.016 · Cited by 81
Evaluation of the protective efficacy of a commercial vaccine against different antigenic groups of H9N2 influenza viruses in chickens
Sun, Y., Pu, J., Fan, L., Sun, H., Wang, J., Zhang, Y., Liu, L., & Liu, J. (2011) · Veterinary Microbiology · doi:10.1016/j.vetmic.2011.10.003 · Cited by 75
Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections
Chen, J.-R., Yu, Y., Tseng, Y.-C., Chiang, W.-L., Chiang, M.-F., Ko, Y., Chiu, Y.-K., Ma, H., Wu, C., Jan, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323954111 · Cited by 73
Advances in therapeutic applications of silver nanoparticles
Kaushal, A., Khurana, I., Yadav, P., Allawadhi, P., Banothu, A. K., Neeradi, D., Thalugula, S., Barani, P. J., Navik, U., Navik, U., et al. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110590 · Cited by 71
Breathing and Tilting: Mesoscale Simulations Illuminate Influenza Glycoprotein Vulnerabilities
Casalino, L., Seitz, C., Lederhofer, J., Tsybovsky, Y., Wilson, I. A., Kanekiyo, M., & Amaro, R. E. (2022) · ACS Central Science · doi:10.1021/acscentsci.2c00981 · Cited by 73
Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method
Dou, D., Hernández-Neuta, I., Wang, H., Østbye, H., Qian, X., Thiele, S., Resa‐Infante, P., Kouassi, N. M., Sender, V., Hentrich, K., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.06.021 · Cited by 64
Infection of HLA-DR1 Transgenic Mice with a Human Isolate of Influenza A Virus (H1N1) Primes a Diverse CD4 T-Cell Repertoire That Includes CD4 T Cells with Heterosubtypic Cross-Reactivity to Avian (H5N1) Influenza Virus
Richards, K. A., Chaves, F. A., & Sant, A. J. (2009) · Journal of Virology · doi:10.1128/jvi.00302-09 · Cited by 65
Pandemic preparedness through vaccine development for avian influenza viruses
Faccin, F. C., & Perez, D. R. (2024) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2024.2347019 · Cited by 60
A Novel Subnucleocapsid Nanoplatform for Mucosal Vaccination against Influenza Virus That Targets the Ectodomain of Matrix Protein 2
Hervé, P., Raliou, M., Bourdieu, C., Dubuquoy, C., Petit‐Camurdan, A., Bertho, N., Eléouët, J., Chevalier, C., & Riffault, S. (2013) · Journal of Virology · doi:10.1128/jvi.01141-13 · Cited by 55
Conjunction of factors triggering waves of seasonal influenza
Chattopadhyay, I., Kıcıman, E., Elliott, J. W., Shaman, J. L., & Rzhetsky, A. (2018) · eLife · doi:10.7554/elife.30756 · Cited by 55
Vaccines in Veterinary Medicine: A Brief Review of History and Technology
McVey, S., & Shi, J. N. (2010) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2010.02.001 · Cited by 54
Darwinian interventions: taming pathogens through evolutionary ecology
Williams, P. D. (2009) · Trends in Parasitology · doi:10.1016/j.pt.2009.11.009 · Cited by 54
Reassortment with Dominant Chicken H9N2 Influenza Virus Contributed to the Fifth H7N9 Virus Human Epidemic
Pu, J., Yin, Y., Liu, J., Wang, X., Zhou, Y., Wang, Z., Sun, Y., Sun, H., Li, F., Song, J., et al. (2021) · Journal of Virology · doi:10.1128/jvi.01578-20 · Cited by 53
Estimating reassortment rates in co-circulating Eurasian swine influenza viruses
Lycett, S., Baillie, G. J., Coulter, E., Bhatt, S., Kellam, P., McCauley, J. W., Wood, J. L. N., Brown, I. H., Pybus, O. G., & Brown, A. (2012) · Journal of General Virology · doi:10.1099/vir.0.044503-0 · Cited by 52
Universal influenza vaccines: from viruses to nanoparticles
Wang, Y., Deng, L., Kang, S., & Wang, B. (2018) · Expert Review of Vaccines · doi:10.1080/14760584.2018.1541408 · Cited by 49
Antibody specificity and promiscuity
Jain, D., & Salunke, D. M. (2019) · Biochemical Journal · doi:10.1042/bcj20180670 · Cited by 47
Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009–2013 and selection of a candidate vaccine strain with broad cross-reactivity
Wei, Y., Xu, G., Zhang, G., Wen, C., Anwar, F., Wang, S., Lemmon, G., Wang, J., Carter, R., Wang, M., et al. (2015) · Veterinary Microbiology · doi:10.1016/j.vetmic.2015.10.031 · Cited by 47
Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview
Mehra, R., & Kepp, K. P. (2021) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.1c00433 · Cited by 45
Strain-specific protective immunity following vaccination against experimental Trypanosoma cruzi infection
Haolla, F. A., Claser, C., de Alencar, B. C., Tzelepis, F., Vasconcelos, J. R., de Oliveira, G., Silvério, J. C., Machado, A. V., Lannes-Vieira, J., Bruña–Romero, O., et al. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.07.013 · Cited by 44
Beyond the Pandemic Era: Recent Advances and Efficacy of SARS-CoV-2 Vaccines Against Emerging Variants of Concern
Saha, A., Roy, S. G., Dwivedi, R., Tripathi, P., Kumar, K., Nambiar, S. M., & Pathak, R. (2025) · Vaccines · doi:10.3390/vaccines13040424 · Cited by 47
Response of Gray Foxes to Modified Live-Virus Canine Distemper Vaccines
Halbrooks, R. D., Swango, L. J., Schnurrenberger, P. R., Mitchell, F. E., & Hill, E. P. (1981) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1981.179.11.1170 · Cited by 42
Herbal Medicine Additives as Powerful Agents to Control and Prevent Avian Influenza Virus in Poultry – A Review
Gado, A. R., Ellakany, H. F., Elbestawy, A. R., El-Hack, M. E. A., Khafaga, A. F., Taha, A. E.-S., Arif, M. A., & Mahgoub, S. A. (2019) · Annals of Animal Science · doi:10.2478/aoas-2019-0043 · Cited by 40
Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highly Pathogenic H5N1
Abdelwhab, E. M., & Hafez, H. (2012) · Viruses · doi:10.3390/v4113179 · Cited by 40
Emerged HA and NA Mutants of the Pandemic Influenza H1N1 Viruses with Increasing Epidemiological Significance in Taipei and Kaohsiung, Taiwan, 2009–10
Kao, C., Chan, T., Tsai, C.-H., Chu, K.-Y., Chuang, S.-F., Lee, C., Li, Z.-R. T., Wu, K.-W., Chang, L., Shen, Y.-H., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031162 · Cited by 38
Viral evolution and transmission effectiveness
Rodpothong, P. (2012) · World Journal of Virology · doi:10.5501/wjv.v1.i5.131 · Cited by 38
OpenFluDB, a database for human and animal influenza virus
Liechti, R., Gleizes, A., Kuznetsov, D. A., Bougueleret, L., Mercier, P. L., Bairoch, A., & Xénarios, I. (2010) · Database · doi:10.1093/database/baq004 · Cited by 38
Addition of N-glycosylation sites on the globular head of the H5 hemagglutinin induces the escape of highly pathogenic avian influenza A H5N1 viruses from vaccine-induced immunity
Hervé, P., Lorin, V., Jouvion, G., Costa, B. D., & Escriou, N. (2015) · Virology · doi:10.1016/j.virol.2015.08.033 · Cited by 36
Substantial Antigenic Drift in the Hemagglutinin Protein of Swine Influenza A Viruses
Ryt‐Hansen, P., Pedersen, A. G., Larsen, I., Kristensen, C. S., Krog, J. S., Wacheck, S., & Larsen, L. E. (2020) · Viruses · doi:10.3390/v12020248 · Cited by 35
The Role of Gut Microbiota in the Modulation of Pulmonary Immune Response to Viral Infection Through the Gut-Lung Axis
Chen, N., Li, L., Han, Y., & Chen, Z. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s525880 · Cited by 41
Utilization of serologic assays to support efficacy of vaccines in nonclinical and clinical trials: Meeting at the Crossroads
Madore, D. V., Meade, B. D., Rubin, F. A., Deal, C. D., & Lynn, F. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.04.094 · Cited by 33
Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?
Zhan, W., Muhuri, M., Tai, P. W. L., & Gao, G. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.673699 · Cited by 35
Influenza vaccine: a review on current scenario and future prospects
Gupta, D., & Mohan, S. (2023) · Journal of Genetic Engineering and Biotechnology · doi:10.1186/s43141-023-00581-y · Cited by 32
Aptamers for Detection and Diagnostics (ADD): Can mobile systems process optical data from aptamer sensors to identify molecules indicating presence of SARS-CoV-2 virus? Should healthcare explore aptamers as drugs for prevention as well as its use as adjuvants with antibodies and vaccines?Preprint
Datta, S. (2020) · ChemRxiv · doi:10.26434/chemrxiv.13102877 · Cited by 31
The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity
Richards, K. A., Chaves, F. A., & Sant, A. J. (2011) · Immunology · doi:10.1111/j.1365-2567.2011.03435.x · Cited by 31
Vaccination with recombinant 4×M2e.HSP70c fusion protein as a universal vaccine candidate enhances both humoral and cell-mediated immune responses and decreases viral shedding against experimental challenge of H9N2 influenza in chickens
Dabaghian, M., Latifi, A. M., Tebianian, M., Nili, H., Ranjbar, A. R. T., Mirjalili, A., Mohammadi, M., Banihashemi, R., & Ebrahimi, S. M. (2014) · Veterinary Microbiology · doi:10.1016/j.vetmic.2014.09.009 · Cited by 31
CAF01 Potentiates Immune Responses and Efficacy of an Inactivated Influenza Vaccine in Ferrets
Martel, C. J., Agger, E. M., Poulsen, J. J., Jensen, T. H., Andresen, L. O., Christensen, D., Nielsen, L. P., Blixenkrone-Møller, M., Andersen, P. L., & Aasted, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022891 · Cited by 30
Convolutional Neural Network Based Approach to In Silico Non-Anticipating Prediction of Antigenic Distance for Influenza Virus
Forghani, M., & Khachay, M. (2020) · Viruses · doi:10.3390/v12091019 · Cited by 27
Age profile of immunity to influenza: Effect of original antigenic sin
Kucharski, A. J., & Gog, J. R. (2011) · Theoretical Population Biology · doi:10.1016/j.tpb.2011.12.006 · Cited by 27
Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines
Subramanian, R., Graham, A. L., Grenfell, B. T., & Arinaminpathy, N. (2016) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005204 · Cited by 28
Passage Adaptation Correlates With the Reduced Efficacy of the Influenza Vaccine
Chen, H., Alvarez, J. J. S., Ng, S. H., Nielsen, R., & Zhai, W. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy1065 · Cited by 28
Structural Basis for the Development of Avian Virus Capsids That Display Influenza Virus Proteins and Induce Protective Immunity
Pascual, E., Mata, C. P., Gómez-Blanco, J., Moreno, N., Bárcena, J., Blanco, E., Rodríguez-Frandsen, A., Nieto, A., Carrascosa, J. L., & Castón, J. R. (2014) · Journal of Virology · doi:10.1128/jvi.03025-14 · Cited by 27
Heterosubtypic protection conferred by combined vaccination with M2e peptide and split influenza vaccine
Wu, F., Yuan, X., Huang, W., & Chen, Y. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.11.037 · Cited by 26
1918 Grip Pandemisi Kıssasından COVID-19 Pandemisine Hisseler
TEMEL, M. K., & Ertin, H. (2020) · Anadolu Kliniği Tıp Bilimleri Dergisi · doi:10.21673/anadoluklin.716868 · Cited by 24
Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing
Poelvoorde, L. A. E. V., Delcourt, T., Coucke, W., Herman, P., Keersmaecker, S. C. J. D., Saelens, X., Roosens, N. H. C., & Vanneste, K. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.747458 · Cited by 26
The Role of Social Contacts and Original Antigenic Sin in Shaping the Age Pattern of Immunity to Seasonal Influenza
Kucharski, A. J., & Gog, J. R. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002741 · Cited by 26
Decline in Seasonal Influenza Vaccine Effectiveness With Vaccination Program Maturation: A Systematic Review and Meta-analysis
Okoli, G. N., Racovitan, F., Abdulwahid, T., Hyder, S. K., Lansbury, L., Righolt, C. H., Mahmud, S. M., & Nguyen‐Van‐Tam, J. S. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab069 · Cited by 27
Trafficking and retention of protein antigens across systems and immune cell types
Doan, T. A., Forward, T. S., & Tamburini, B. A. J. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04303-4 · Cited by 24
Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions
Hsiung, K. C., Chiang, H.-J., Reinig, S., & Shih, S. (2024) · Vaccines · doi:10.3390/vaccines12121345 · Cited by 25
Antigenicity, pathogenicity and immunosuppressive effect caused by a South American isolate of infectious bursal disease virus belonging to the “distinct” genetic lineage
Tomás, G., Marandino, A. E., Courtillon, C., Amelot, M., Keïta, A., Pikuła, A., Hernández, M. A., Hernández, D., Vagnozzi, A. E., Panzera, Y., et al. (2019) · Avian Pathology · doi:10.1080/03079457.2019.1572867 · Cited by 24
Timing of Pathogen Adaptation to a Multicomponent Treatment
Bourget, R., Chaumont, L., & Sapoukhina, N. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071926 · Cited by 23
Navigating the Devious Course of Evolution: The Importance of Mechanistic Models for Identifying Eco-Evolutionary Dynamics in Nature
Luo, S., & Koelle, K. (2013) · The American Naturalist · doi:10.1086/669952 · Cited by 19
Molecular evolution of the hemagglutinin and neuraminidase genes of pandemic (H1N1) 2009 influenza viruses in Sendai, Japan, during 2009–2011
Khandaker, I., Suzuki, A. K., Kamigaki, T., Tohma, K., Odagiri, T., Okada, T., Ohno, A., Otani, K., Sawayama, R., Kawamura, K., et al. (2013) · Virus Genes · doi:10.1007/s11262-013-0980-5 · Cited by 21
Effects of vaccination and population structure on influenza epidemic spread in the presence of two circulating strains
Alexander, M. E., & Kobes, R. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-s1-s8 · Cited by 21
Development of mRNA vaccines and their prophylactic and therapeutic applications
Lee, K., Kim, M., Seo, Y., & Lee, H. (2018) · Nano Research · doi:10.1007/s12274-018-2095-8 · Cited by 23
Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8+ T cells
Mix, M. R., van de Wall, S., Heidarian, M., Escue, E., Fain, C. E., Pewe, L. L., Hancox, L. S., Arumugam, S. A., Sievers, C. M., Badovinac, V. P., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115247 · Cited by 18
Effect of seasonal vaccination on the selection of influenza A/H3N2 epidemic variants
Chong, Y., & Ikematsu, H. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.11.084 · Cited by 17
Influential factors inducing suboptimal humoral response to vector-based influenza immunisation in Thoroughbred foals
Fougerolle, S., Legrand, L. J., Garrett, D., Birand, I., Foursin, M., D'Ablon, X., Bayssat, P., Newton, R. J., Pronost, S. L., & Paillot, R. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.05.068 · Cited by 17
Broadly Protective Neuraminidase-Based Influenza Vaccines and Monoclonal Antibodies: Target Epitopes and Mechanisms of Action
Abbadi, N., & Mousa, J. J. (2023) · Viruses · doi:10.3390/v15010200 · Cited by 17
Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub
Jung, S.-M., Loo, S. L., Howerton, E., Contamin, L., Smith, C. P., Carcelén, E. C., Yan, K., Bents, S. J., Levander, J. D., Espino, J. U., et al. (2024) · PLoS Medicine · doi:10.1371/journal.pmed.1004387 · Cited by 15
A mathematical model simulating the adaptive immune response in various vaccines and vaccination strategies
Xu, Z., Song, J. H., Zhang, H., Wei, Z., Wei, D., Guangyu, Y., Jacques Demongeot, A., & Zeng, Q. (2024) · Scientific Reports · doi:10.1038/s41598-024-74221-x · Cited by 15
The Perspective on Bio-Nano Interface Technology for Covid-19
Kamaraj, S. (2020) · Frontiers in Nanotechnology · doi:10.3389/fnano.2020.586250 · Cited by 15
Optimal Design of the Seasonal Influenza Vaccine with Manufacturing Autonomy
Özaltın, O. Y., Prokopyev, O. A., & Schaefer, A. J. (2018) · INFORMS journal on computing · doi:10.1287/ijoc.2017.0786 · Cited by 14
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants
Yan, Q., Gao, X., Liu, B., Hou, R., He, P., Ma, Y., Zhang, Y., Zhang, Y., Li, Z., Chen, Q., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51770-3 · Cited by 15
Molecular Characterization of Seasonal Influenza A and B from Hospitalized Patients in Thailand in 2018–2019
Boonnak, K., Mansanguan, C., Schuerch, D., Boonyuen, U., Lerdsamran, H., Jiamsomboon, K., Wang, F. S., Huntrup, A., Prasertsopon, J., Kosoltanapiwat, N., et al. (2021) · Viruses · doi:10.3390/v13060977 · Cited by 14
Intestinal microbiota analysis and network pharmacology reveal the mechanism by which Lianhua Qingwen capsule improves the immune function of mice infected with influenza A virus
Xu, P., Yang, Z., Du, S., Hong, Z., & Zhong, S. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1035941 · Cited by 14
Statistical identifiability and sample size calculations for serial seroepidemiology
Vinh, D. N., & Boni, M. F. (2015) · Epidemics · doi:10.1016/j.epidem.2015.02.005 · Cited by 11
Self-citation
Genotypic evolution and antigenicity of H9N2 influenza viruses in Shanghai, China
Ge, F., Li, X., Ju, H., Yang, D., Liu, J., Qi, X., Wang, J., Yang, X., Qiu, Y., Liu, P., et al. (2016) · Archives of Virology · doi:10.1007/s00705-016-2767-1 · Cited by 14
CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age
Menon, T., Illing, P. T., Chaurasia, P., McQuilten, H. A., Shepherd, C. M., Rowntree, L. C., Petersen, J., Littler, D. R., Khuu, G., Huang, Z., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47576-y · Cited by 13
RETRACTED ARTICLE: Comparing Moderna’s mRNA-1083 and Pfizer’s dual-target mRNA vaccines for influenza and COVID-19
Akingbola, A., Christopher, A. A., Adegoke, K., Idahor, C. O., Mariaria, P. K., Peters, F., Salami, R. A., Ojo, O., Nwaeze, E., Abdullahi, O., et al. (2025) · npj Vaccines · doi:10.1038/s41541-025-01145-6 · Cited by 16
Retracted
An Antigenic Thrift-Based Approach to Influenza Vaccine Design
Bolton, J. S., Klim, H., Wellens, J., Edmans, M. D., Obolski, U., & Thompson, C. (2021) · Vaccines · doi:10.3390/vaccines9060657 · Cited by 13
A Review on Equine Influenza from a Human Influenza Perspective
Whitlock, F., Murcia, P. R., & Newton, J. R. (2022) · Viruses · doi:10.3390/v14061312 · Cited by 13
Influenza vaccine effectiveness assessment through sentinel virological data in three post-pandemic seasons
Torner, N., Martı́nez, A., Basile, L., Marcos, M. Á., Antón, A., Mosquera, M., Isanta, R., Cabezas, C., Jané, M., Domı́nguez, Á., et al. (2014) · Human Vaccines & Immunotherapeutics · doi:10.4161/hv.36155 · Cited by 13
The evolutionary dynamics of receptor binding avidity in influenza A: a mathematical model for a new antigenic drift hypothesis
Yuan, H., & Koelle, K. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0204 · Cited by 13
Structural basis of fitness of emerging SARS-COV-2 variants and considerations for screening, testing and surveillance strategy to contain their threatPreprint
Islam, S. R., Prusty, D., & Manna, S. K. (2021) · medRxiv · doi:10.1101/2021.01.28.21250666 · Cited by 13
Lung cell fates during influenza
Jarboe, B., Shubina, M., Langlois, R. A., Boyd, D. F., & Balachandran, S. (2025) · Cell Research · doi:10.1038/s41422-025-01163-y · Cited by 15
Influenza A genomic diversity during human infections underscores the strength of genetic drift and the existence of tight transmission bottlenecks
Martin, M. A., Berg, N., & Koelle, K. (2024) · Virus Evolution · doi:10.1093/ve/veae042 · Cited by 12
Antigenicity and transmissibility of a novel clade 2.3.2.1 avian influenza H5N1 virus
Xu, L., Bao, L., Yuan, J., Li, F., Lv, Q., Deng, W., Xu, Y., Yao, Y., Yü, P., Chen, H., et al. (2013) · Journal of General Virology · doi:10.1099/vir.0.057778-0 · Cited by 12

Authors: Boni, M. F.
Affiliations: Resources For The Future (US)
Corresponding author: Boni, Maciej F.
ORCID: Boni, Maciej F.
Venue: Vaccine
Publisher: Elsevier BV
Published: 2008-07
Volume: 26
Pages: C8-C14
ISSN: 0264-410X (ISSN-L)
DOI: 10.1016/j.vaccine.2008.04.011
PMC: PMC2603026
OpenAlex: W2023224232
Cited by: 226
References: 48
Citations by year: 2026: 11 · 2025: 13 · 2024: 13 · 2023: 8 · 2022: 14 · 2021: 47 · 2020: 19 · 2019: 9 · 2018: 10 · 2017: 8 · 2016: 9 · 2015: 4 · 2014: 8 · 2013: 10 · 2012: 8
FWCI: 1.18
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Vaccine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Human Genome Research Institute (F32HG000205, HG000205, P01HG000205)
National Institute of General Medical Sciences (GM28016, R01GM028016)
Topics: Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
Keywords: influenza vaccination, seasonal influenza, herd immunity, vaccine update, vaccine selection
MeSH terms: Antigenic Variation, Biological Evolution, Humans, Influenza, Human, Influenza Vaccines, Vaccination, Virulence, Genetic Drift, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Vaccination and antigenic drift in influenza

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks