Resolution of canine ocular thelaziosis in avermectin-sensitive Border Collies from Spain
Abstract
Ocular thelaziosis by Thelazia callipaeda is an emerging disease that affects primarily dogs, but also cats, foxes and other wild carnivores, as well as humans. Three clinical cases of unilateral conjunctivitis caused by Thelazia nematodes were detected in Border Collie, a dog breed intolerant to the macrocyclic lactones. Animals came from southwestern Spain, on the border with Portugal. Eight worms were collected and identified molecularly as T. callipaeda by amplification and sequencing of partial cytochrome c oxidase subunit 1 gene. Oral treatment with mebendazole 20mg/kg (Telmin(®)) was effective in curing the infection.
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Mebendazole (20 mg/kg daily for 3 days) was shown to be effective for cure of thelaziasis infection in dogs.
“mebendazole (20 mg/kg daily for 3 days) was also shown to be effective for cure of the infection in dogs [151]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [151]
Cites
Thelazia callipaeda: infection in dogs: a new parasite for Spain
Miró, G., Montoya, A., Hernández, L., Dado, D., Vázquez, M. V., Benito, M., Villagrasa, M., Brianti, E., & Otranto, D. (2011) · Parasites & Vectors · doi:10.1186/1756-3305-4-148 · Cited by 99 · see citing works
Self-citationFirst report of canine ocular thelaziosis by Thelazia callipaeda in Portugal
Vieira, L., Rodrigues, F. T., Costa, Á., Diz-Lopes, D., Machado, J., Coutinho, T., Tuna, J., Latrofa, M. S., Cardoso, L., & Otranto, D. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-124 · Cited by 61 · see citing works
Self-citationLia, R. P., Traversa, D., Agostini, A., & Otranto, D. (2004) · Veterinary Record · doi:10.1136/vr.154.5.143 · Cited by 38 · see citing works
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Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286 · see citing works
- Authors
- Calero-Bernal, R., Sánchez-Murillo, J. M., Alarcón-Elbal, P. M., Sánchez-Moro, J., Latrofa, M. S., Dantas-Torres, F., & Otranto, D.
- Affiliations
- University of Bari Aldo Moro (IT)
- Venue
- Veterinary Parasitology
- Publisher
- Elsevier BV
- Published
- 2014-02
- Volume
- 200
- Issue
- 1-2
- Pages
- 203-206
- ISSN
- 0304-4017 (ISSN-L)
- OpenAlex
- W1968004962
- Cited by
- 14
- References
- 3
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2016: 2 · 2015: 2 · 2014: 2
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Veterinary Parasitology (publishedVersion)
- PubMed (publishedVersion)
- Arca - Repositório Institucional da Fiocruz (submittedVersion)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion)
- Funders
- Regional Government of Extremadura
- European Social Fund
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Keywords
- Thelazia callipaeda, Border Collie, conjunctivitis, mebendazole, cytochrome c oxidase subunit I, molecular identification, emerging zoonotic diseases
- MeSH terms
- Animals, Antinematodal Agents, Dog Diseases, Dogs, Female, Male, Mebendazole, Spain, Thelazioidea, Treatment Outcome, Spirurida Infections
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