The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The human papillomavirus E7 oncoprotein
Open accessAbstract
The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins always expressed in HPV-associated cancers, E7 plays a central role in both the viral life cycle and carcinogenic transformation. In the HPV viral life cycle, E7 disrupts the intimate association between cellular differentiation and proliferation in normal epithelium, allowing for viral replication in cells that would no longer be in the dividing population. This function is directly reflected in the transforming activities of E7, including tumor initiation and induction of genomic instability.
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Cites
pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest
Hannon, G. J., & Beach, D. (1994) · Nature · doi:10.1038/371257a0 · Cited by 1,950
Zhang, Y., Xiong, Y., & Yarbrough, W. G. (1998) · Cell · doi:10.1016/s0092-8674(00)81401-4 · Cited by 1,626
Frisch, S. M., & Screaton, R. A. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00251-9 · Cited by 1,249
Cited by
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Lau, L., Gray, E. E., Brunette, R. L., & Stetson, D. B. (2015) · Science · doi:10.1126/science.aab3291 · Cited by 453
Historical review of the causes of cancer
Blackadar, C. B. (2016) · World Journal of Clinical Oncology · doi:10.5306/wjco.v7.i1.54 · Cited by 389
Moody, C. A., & Laimins, L. A. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000605 · Cited by 371
The landscape of viral expression and host gene fusion and adaptation in human cancer
Tang, K.-W., Alaei-Mahabadi, B., Samuelsson, T., Lindh, M., & Larsson, E. (2013) · Nature Communications · doi:10.1038/ncomms3513 · Cited by 301
Honegger, A., Schilling, D., Bastian, S., Sponagel, J., Kuryshev, V., Sültmann, H., Scheffner, M., Hoppe-Seyler, K., & Hoppe-Seyler, F. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1004712 · Cited by 222
Metadata
- Authors
- McLaughlin-Drubin, M. E., & Münger, K.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 384
- Issue
- 2
- Pages
- 335-344
- ISSN
- 0042-6822 (ISSN-L)
- OpenAlex
- W1975728570
- Cited by
- 391
- References
- 3
- FWCI
- 15.33
- Type
- journal article
- Language
- en
- Open access
- bronze
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- McLaughlin-Drubin, M. E., & Münger, K. (2009). The human papillomavirus E7 oncoprotein. Virology. https://doi.org/10.1016/j.virol.2008.10.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
