The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration
Open accessAbstract
Age-related Macular Degeneration (AMD) is the leading cause of blindness among the elderly. While excellent treatment has emerged for neovascular disease, treatment for early AMD is lacking due to an incomplete understanding of the early molecular events. Cigarette smoking is the strongest epidemiologic risk factor, yet we do not understand how smoking contributes to AMD. Smoking related oxidative damage during the early phases of AMD may play an important role. This review explores how cigarette smoking and oxidative stress to the retinal pigmented epithelium (RPE) might contribute to AMD, and how the transcription factor Nrf2 can activate a cytoprotective response.
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Cites
Complement factor H polymorphism in age-related macular degeneration
Klein, R. J., Zeiss, C., Chew, E. Y., Tsai, J.-Y., Sackler, R. S., Haynes, C., Henning, A. K., SanGiovanni, J. P., Mane, S. M., Mayne, S. T., et al. (2005) · Science · doi:10.1126/science.1109557 · Cited by 4,492
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Complement factor H polymorphism and age-related macular degeneration
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Complement factor H variant increases the risk of age-related macular degeneration
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Nrf2–Keap1 defines a physiologically important stress response mechanism
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Cited by
The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD
Datta, S., Cano, M., Ebrahimi, K., Wang, L., & Handa, J. T. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.03.002 · Cited by 802
Self-citationLight-emitting diodes (LED) for domestic lighting: Any risks for the eye?
Behar-Cohen, F., Martinsons, C., Viénot, F., Zissis, G., Barlier-Salsi, A., Cesarini, J. P., Enouf, O., Garcia, M., Picaud, S., & Attia, D. (2011) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2011.04.002 · Cited by 416
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Self-citationReinisalo, M., Kårlund, A., Koskela, A., Kaarniranta, K., & Karjalainen, R. O. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/340520 · Cited by 284
Potential Role of Oxidative Stress in Ocular Surface Inflammation and Dry Eye Disease
Dogru, M., Kojima, T., Simsek, C., & Tsubota, K. (2018) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.17-23402 · Cited by 257
Metadata
- Authors
- Cano, M., Thimmalappula, R., Fujihara, M., Nagai, N., Sporn, M., Wang, A. L., Neufeld, A. H., Biswal, S., & Handa, J. T.
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 50
- Issue
- 7
- Pages
- 652-664
- ISSN
- 0042-6989 (ISSN-L)
- OpenAlex
- W2024116613
- Cited by
- 184
- References
- 26
- FWCI
- 9.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration. https://app.cochat.ai/papers/10.1016/j.visres.2009.08.018
- The paper
- Cano, M., Thimmalappula, R., Fujihara, M., Nagai, N., Sporn, M., Wang, A. L., Neufeld, A. H., Biswal, S., & Handa, J. T. (2010). Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration. Vision Research. https://doi.org/10.1016/j.visres.2009.08.018
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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