The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Potential Role of Oxidative Stress in Ocular Surface Inflammation and Dry Eye Disease
Open accessAbstract
Reactive oxygen species (ROS) are produced as a by-product during the mitochondrial respiration of the oxygen and potentially able to damage the tissues. Oxidative stress occurs as a result of the disruption of the balance between the anti-oxidant system and the pro-oxidant system found in cells. It has been accepted that overexpression of ROS can be induced in the ocular surface as a result of many acute and chronic diseases and even in normal aging. Recent studies demonstrated that oxidative stress damages the ocular surface and plays an important role in the mechanism of dry eye disease. There is a need to investigate the therapeutic modalities employing topical/systemic use of antioxidants in dry eye disease. This review will summarize the recent studies showing the important relationship between oxidative stress and dry eye disease.
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Cites
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Cited by
Pisoschi, A. M., Pop, A., Iordache, F., Stanca, L., Predoi, G., & Serban, A. I. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112891 · Cited by 816
Antioxidant Nutraceutical Strategies in the Prevention of Oxidative Stress Related Eye Diseases
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Ling, J., Chan, C.-L., Ho, C.-Y., Gao, X., Tsang, S.-M., Leung, P.-C., Hu, J.-M., & Wong, C.-K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911195 · Cited by 31
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Li, X., Meng, F., Li, H., Hua, X., Wu, L., & Yuan, X. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4283 · Cited by 20
Metadata
- Authors
- Dogru, M., Kojima, T., Simsek, C., & Tsubota, K.
- Venue
- Investigative Opthalmology & Visual Science
- Published
- 2018-11-27
- Volume
- 59
- Issue
- 14
- Pages
- DES163
- ISSN
- 0146-0404 (ISSN-L)
- 1552-5783
- OpenAlex
- W2902388601
- Cited by
- 257
- References
- 32
- FWCI
- 15.86
- Type
- journal article
- Language
- en
- Open access
- gold
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