The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Arterial stiffness, atherosclerosis and cardiovascular risk: Pathophysiologic mechanisms and emerging clinical indications
Open accessAbstract
Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix proteins and in the mechanical properties of the vessel wall related to arterial stiffening may activate number of mechanisms involved also in the process of atherosclerosis. Several noninvasive methods are now available to estimate large artery stiffness in the clinical setting, including carotid-femoral pulse wave velocity, the reference for aortic stiffness estimate, and local distensibility measures of superficial arteries, namely carotid and femoral. An independent predictive value of arterial stiffness for cardiovascular events has been demonstrated in general as well as in selected populations, and reference values adjusted for age and blood pressure have been established. Thus, arterial stiffness is emerging as an interesting tissue biomarker for cardiovascular risk stratification and estimation of the individual "biological age". This paper overviews the mechanisms accounting for development and progression of arterial stiffness and for associations between arterial stiffness, atherosclerotic burden and incident cardiovascular events, summarizes the evidence and caveat for clinical use of stiffness as surrogate marker of cardiovascular risk, and briefly outlines some emerging methods for large artery stiffness characterization.
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Cites
Expert consensus document on arterial stiffness: methodological issues and clinical applications
Laurent, S., Cockcroft, J., Van Bortel, L., Boutouyrie, P., Giannattasio, C., Hayoz, D., Pannier, B., Vlachopoulos, C., Wilkinson, I., Struijker-Boudier, H., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl254 · Cited by 6,077
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Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856
Impact of Aortic Stiffness on Survival in End-Stage Renal Disease
Blacher, J., Guerin, A. P., Pannier, B., Marchais, S. J., Safar, M. E., & London, G. M. (1999) · Circulation · doi:10.1161/01.cir.99.18.2434 · Cited by 2,138
Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction
Ben-Shlomo, Y., Spears, M., Boustred, C., May, M., Anderson, S. G., Benjamin, E. J., Boutouyrie, P., Cameron, J., Chen, C.-H., Cruickshank, J. K., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.063 · Cited by 1,835
Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation
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Cited by
Lim, H. Y., Lim, S. Y., Tan, C. K., Thiam, C. H., Goh, C. C., Carbajo, D., Chew, S. H. S., See, P., Chakarov, S., Wang, X. N., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.06.008 · Cited by 384
Senescent cells: a therapeutic target for cardiovascular disease
Childs, B. G., Li, H., & van Deursen, J. M. (2018) · Journal of Clinical Investigation · doi:10.1172/jci95146 · Cited by 192
Biophysical regulation of macrophages in health and disease
Meli, V. S., Veerasubramanian, P. K., Atcha, H., Reitz, Z., Downing, T. L., & Liu, W. F. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.mr0318-126r · Cited by 133
Mechanosensing in macrophages and dendritic cells in steady-state and disease
Lee, M., Du, H., Winer, D. A., Clemente-Casares, X., & Tsai, S. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1044729 · Cited by 99
Walker, M. A., Bailey, T. G., McIlvenna, L., Allen, J. D., Green, D. J., & Askew, C. D. (2019) · Nutrients · doi:10.3390/nu11050954 · Cited by 61
Metadata
- Authors
- Palombo, C., & Kozakova, M.
- Venue
- Vascular Pharmacology
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 77
- Pages
- 1-7
- ISSN
- 1537-1891 (ISSN-L)
- OpenAlex
- W2178867594
- Cited by
- 476
- References
- 6
- FWCI
- 18.74
- Type
- journal article
- Language
- en
- Open access
- green
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- Palombo, C., & Kozakova, M. (2016). Arterial stiffness, atherosclerosis and cardiovascular risk: Pathophysiologic mechanisms and emerging clinical indications. Vascular Pharmacology. https://doi.org/10.1016/j.vph.2015.11.083
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
