The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Thermo activated persulfate oxidation of antibiotic sulfamethoxazole and structurally related compounds
Abstract
The widespread occurrence of sulfonamides (e.g., sulfamethoxazole) in natural environment has raised growing concerns due to their potential to induce antibiotic-resistant genes. In this study, the degradation of SMX and related sulfonamides by thermo activated persulfate (PS) oxidation was investigated. Experimental results demonstrated that SMX degradation followed pseudo-first-order reaction kinetics. The pseudo-first-order rate constant (k(obs)) was increased markedly with increasing temperature and pH. The presence of bicarbonate manifested promoting effect on SMX degradation while fulvic acid reduced it. Radical scavenging tests revealed that the predominant oxidizing species was SO4(•-) at neutral pH. Aniline moiety in SMX molecule was confirmed to be the primary reactive site for SO4(•-) attack by comparison with substructural analogues. Reaction products were enriched by solid phase extraction (SPE) and analyzed by liquid chromatography-electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS). A total of 7 products derived from hydroxylation, sulfonamide S-N bond cleavage, aniline moiety oxidation and coupling reaction were identified, and transformation pathways of SMX oxidation were proposed. Degradation of sulfonamides was appreciably influenced by the heterocyclic ring present in the molecules. Results reveal that thermo activated PS oxidation could be an efficient approach for remediation of water contaminated by SMX and related sulfonamides.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Degradation increased from 50% to 99% withHCO 3 - ions”
From Advanced Oxidation Processes for Degradation of Water Pollutants—Ambivalent Impact of Carbonate Species: A Review (2023) · cites this paper as [68]
Citations
Cites
Antibiotics in the aquatic environment – A review – Part I
Kümmerer, K. (2009) · Chemosphere · doi:10.1016/j.chemosphere.2008.11.086 · Cited by 4,485
Pignatello, J. J., Oliveros, E., & MacKay, A. (2006) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643380500326564 · Cited by 4,133
Rate Constants for Reactions of Inorganic Radicals in Aqueous Solution
Neta, P., Huie, R. E., & Ross, A. B. (1988) · Journal of Physical and Chemical Reference Data · doi:10.1063/1.555808 · Cited by 3,651
Sarmah, A. K., Meyer, M. T., & Boxall, A. B. A. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2006.03.026 · Cited by 3,326
Radical Generation by the Interaction of Transition Metals with Common Oxidants
Anipsitakis, G. P., & Dionysiou, D. D. (2004) · Environmental Science & Technology · doi:10.1021/es035121o · Cited by 3,088
Rizzo, L., Manaia, C., Merlin, C., Schwartz, T., Dagot, C., Ploy, M. C., Michael, I., & Fatta-Kassinos, D. (2013) · Science of The Total Environment · doi:10.1016/j.scitotenv.2013.01.032 · Cited by 2,493
Michael, I., Rizzo, L., McArdell, C. S., Manaia, C. M., Merlin, C., Schwartz, T., Dagot, C., & Fatta‐Kassinos, D. (2012) · Water Research · doi:10.1016/j.watres.2012.11.027 · Cited by 2,025
Emerging organic contaminants in groundwater: A review of sources, fate and occurrence
Lapworth, D. J., Baran, N., Stuart, M. E., & Ward, R. S. (2012) · Environmental Pollution · doi:10.1016/j.envpol.2011.12.034 · Cited by 1,995
Pharmaceuticals and endocrine disrupting compounds in U.S. drinking water
Benotti, M. J., Trenholm, R. A., Vanderford, B. J., Holady, J. C., Stanford, B. D., & Snyder, S. A. (2009) · Environmental Science & Technology · doi:10.1021/es801845a · Cited by 1,681
Oxidation of Pharmaceuticals during Ozonation and Advanced Oxidation Processes
Huber, M. M., Canonica, S., Park, G.-Y., & von Gunten, U. (2003) · Environmental Science & Technology · doi:10.1021/es025896h · Cited by 1,619
Flagged first, then by citations
Cited by
Sorted by citations
Items 401–439 of 439
A review on the use of persulfate activation in treating antibiotics-contaminated wastewater
Wang, Y. (2024) · Highlights in Science Engineering and Technology · doi:10.54097/w9cg5202 · Cited by 1
Xu, Q., Yang, Q., Xie, Y., Wen, X.-J., Fei, Z., & You, H. (2024) · Water Cycle · doi:10.1016/j.watcyc.2024.12.001 · Cited by 1
Hu, C., Yang, X., Hu, L., Liu, H., Chen, J., Gao, L.-M., & Dong, Z.-Y. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.115365 · Cited by 1
Investigation of amoxicillin removal efficiency from aqueous solutions using US/PS/CuO-Fe3O4 process
Nazari, S. B., Fazlzadeh, M., Parastar, S., Aaligadri, M., Rashtbari, Y., & Poureshgh, Y. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42618 · Cited by 1
Lv, S., Ni, Z., Liu, L., Jiang, S., Shan, M., Cong, Y., Lv, S., Wang, G., Xu, J. J., & Zhang, Y. (2025) · Applied Surface Science · doi:10.1016/j.apsusc.2025.163312 · Cited by 1
Research Progress on Persulfate Activation Technology for Removing Antibiotic Wastewater
王, 杰. (2025) · Advances in Environmental Protection · doi:10.12677/aep.2025.157115 · Cited by 1
Kuna, S., Patlola, M., Bhoomandla, S., Pandiri, S., Akarapu, P., & Allaka, T. R. (2025) · Russian Journal of General Chemistry · doi:10.1134/s1070363225603035 · Cited by 1
Jiang, W., Lao, W., Xu, Z., Feng, Y., & Ruan, J. (2025) · Environmental Science Nano · doi:10.1039/d5en00701a · Cited by 1
Yi, J., Wan, J., Alemán, J., & Wang, Y. (2025) · Environmental Research · doi:10.1016/j.envres.2025.123437 · Cited by 1
Jia, J., Wang, W., Liang, Y., Pan, Z., & Li, C. Y. (2026) · Toxics · doi:10.3390/toxics14010073 · Cited by 1
Chen, K., Wang, J., Cheng, X., Zhang, W., Huang, J., Luo, C., Luo, X., Li, P., Jin, Y., Wu, D., et al. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.141439 · Cited by 1
Self-citationMadhusudhan, A., Gowrisankaran, S., Zažímal, F., Satrapinskyy, L., Roch, T., Homola, T., Dvoranová, D., Brigante, M., & Monfort, O. (2026) · Inorganic Chemistry Frontiers · doi:10.1039/d5qi02441b · Cited by 1
An, S., Kim, T. H., Kim, J. Y., Miller, K. J., Jung, J., Choong, C. E., Jun, B.-M., Park, C. M., Jang, M., Yoon, Y., et al. (2026) · Applied Catalysis B: Environmental · doi:10.1016/j.apcatb.2026.126700 · Cited by 1
Hinal, A. B., Lekshmi, G. S. S., & Gandhimathi, R. (2026) · Journal of Environmental Science and Health Part A · doi:10.1080/10934529.2026.2679385 · Cited by 1
Wang, S., Wu, E.-N., Meng, L., Wang, Z., & Wang, T. (2023) · NANO · doi:10.1142/s1793292023501102 · Cited by 1
Li, Y., Luo, J., Liao, X., Cao, H., Pan, J., & Li, H. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.165840 · Cited by 1
Yao, L., Huang, A., Yang, G., & Wu, S. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.119860 · Cited by 1
Moosavi, S. J., Pazira, A., Tabatabaie, T., Jaafarzadeh, N., & Jorfi, S. (2021) · Desalination and Water Treatment · doi:10.5004/dwt.2021.26862 · Cited by 1
Chen, X. D. (2020) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/136926
Wang, S., & Wang, J. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3969610
Chen, J., Zhu, H., Ren, Q., Chen, S., Ding, Y., Xiong, C., Guo, W., & Jia, X. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3992533
Chen, X., Ma, Y., Zhu, J., Shen, S., Yang, L., Tang, J., & Zhang, Z. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4122139
Destruction of Pharmaceuticals
Lunn, G., & Sansone, E. B. (2023) · Wiley eBooks · doi:10.1002/9781119848851.ch3
Procedures Classified by Method
Lunn, G., & Sansone, E. B. (2023) · doi:10.1002/9781119848851.ch4
Nascimento, C. D. O. C., Palácio, S. M., Veit, M. T., Borba, F. H., Zorzo, C. F., & Amado, D. A. V. (2024) · International Journal of Environmental Studies · doi:10.1080/00207233.2024.2322896
Chen, M., Yang, T., Lei, Q., Gan, X. H., Mao, S., & Zhao, H. (2024) · Angewandte Chemie · doi:10.1002/ange.202416921
Zhang, Z., Zhao, L., Tian, J., Ren, S., & Zhang, W. (2024) · Water · doi:10.3390/w16213109
Chen, S., Huang, Z., Song, Z., Mao, Y., Liu, H., Dou, Y., Kang, H., Jin, H., Huang, Q., & Duan, X. (2025) · ChemistrySelect · doi:10.1002/slct.202404631
Yi, J., Wan, J., Ma, Y., & Ye, G. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5510378
Xu, W., Zhang, C., Shi, W., Zhao, S., & Zhang, B. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.140836
Rehman, F., Khan, M. Y., Sayed, M., Qarni, A. A., Akhtar, N., Al‐Anazi, A., Khan, J. A., Shah, N. S., Ali, F., Razzak, N. R. B., et al. (2026) · International Journal of Chemical Engineering · doi:10.1155/ijce/8004405
Yu, H., Yuan, A., Liu, S., & Yang, L. (2026) · Food Control · doi:10.1016/j.foodcont.2026.112256
Wang, T. C., Shan, Y., Yao, X., Ai, F., Du, W., Sun, Y. W., Wu, J., & Guo, H. (2026) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2026.123631
Heat-activated persulfate degradation of phthalic acid esters: From aqueous to soil systems
Uzamurera, A. G., Zhang, C., Wang, Y., Liu, J., Shan, Y., Jiao, W., & Liu, B. (2026) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2026.124283
Yu, H., Luo, J., Hu, T., Zhang, M., Chai, L., & Qi, C. (2026) · Separation and Purification Technology · doi:10.1016/j.seppur.2026.139996
Studziński, W., Gackowska, A., Kudlek, E., & Przybyłek, M. (2026) · Molecules · doi:10.3390/molecules31183220
Metadata
- Authors
- Ji, Y., Fan, Y., Liu, K., Kong, D., & Lu, J.
- Affiliations
- Nanjing Agricultural University (CN)
- Ministry of Ecology and Environment (CN)
- Corresponding author
- Lu, Junhe
- Venue
- Water Research
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 87
- Pages
- 1-9
- ISSN
- 0043-1354 (ISSN-L)
- OpenAlex
- W1409743805
- Cited by
- 439
- References
- 82
- Citations by year
- 2026: 15 · 2025: 42 · 2024: 38 · 2023: 47 · 2022: 58 · 2021: 49 · 2020: 46 · 2019: 54 · 2018: 44 · 2017: 29 · 2016: 16 · 2015: 1
- FWCI
- 19.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Water Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- China Postdoctoral Research Funds (2015M570454)
- Jiangsu Planned Projects for Postdoctoral Research Funds (1402013A)
- Priority Academic Program Development (PAPD)
- Topics
- Physical Sciences › Environmental Science › Water Science and Technology › Advanced oxidation water treatment
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Environmental Science › Environmental Engineering › Environmental remediation with nanomaterials
- Keywords
- sulfamethoxazole, sulfonamides, sulfate radicals, antibiotic degradation, antibiotic resistance genes, transformation pathways, pseudo-first-order kinetics, water remediation
- MeSH terms
- Aniline Compounds, Anti-Bacterial Agents, Hot Temperature, Kinetics, Oxidation-Reduction, Sulfamethoxazole, Sulfates, Water Pollutants, Chemical
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review