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Cited by 244

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Endothelial cell-cell adhesion and signaling

Open access
Cerutti, Camilla, Ridley, Anne J.·2017·Experimental Cell Research

Abstract

Endothelial cells line blood vessels and provide a dynamic interface between the blood and tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during inflammation and infections. Here we compare the signaling networks that contribute to endothelial permeability and leukocyte transendothelial migration, focusing particularly on signals mediated by small GTPases that regulate cell adhesion and the actin cytoskeleton. Rho and Rap GTPase signaling is important for both processes, but they differ in that signals are activated locally under leukocytes, whereas endothelial permeability is a wider event that affects the whole cell. Some molecules play a unique role in one of the two processes, and could therefore be targeted to selectively alter either endothelial permeability or leukocyte transendothelial migration.

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Metadata

Authors
Cerutti, C., & Ridley, A. J.
Venue
Experimental Cell Research
Publisher
Elsevier BV
Published
2017-09
Volume
358
Issue
1
Pages
31-38
ISSN
0014-4827 (ISSN-L)
OpenAlex
W2623250711
Cited by
244
References
6
FWCI
13.21
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Endothelial cell-cell adhesion and signaling. https://app.cochat.ai/papers/10.1016/j.yexcr.2017.06.003
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Cerutti, C., & Ridley, A. J. (2017). Endothelial cell-cell adhesion and signaling. Experimental Cell Research. https://doi.org/10.1016/j.yexcr.2017.06.003

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.