The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Endothelial cell-cell adhesion and signaling
Open accessAbstract
Endothelial cells line blood vessels and provide a dynamic interface between the blood and tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during inflammation and infections. Here we compare the signaling networks that contribute to endothelial permeability and leukocyte transendothelial migration, focusing particularly on signals mediated by small GTPases that regulate cell adhesion and the actin cytoskeleton. Rho and Rap GTPase signaling is important for both processes, but they differ in that signals are activated locally under leukocytes, whereas endothelial permeability is a wider event that affects the whole cell. Some molecules play a unique role in one of the two processes, and could therefore be targeted to selectively alter either endothelial permeability or leukocyte transendothelial migration.
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Cites
Getting to the site of inflammation: the leukocyte adhesion cascade updated
Ley, K., Laudanna, C., Cybulsky, M. I., & Nourshargh, S. (2007) · Nature Reviews Immunology · doi:10.1038/nri2156 · Cited by 4,354
Crossing the endothelial barrier during metastasis
Reymond, N., d'Água, B. B., & Ridley, A. J. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3628 · Cited by 922
Self-citationZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation
Tornavaca, O., Chia, M., Dufton, N., Almagro, L. O., Conway, D. E., Randi, A. M., Schwartz, M. A., Matter, K., & Balda, M. S. (2015) · Journal of Cell Biology · doi:10.1083/jcb.201404140 · Cited by 585
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Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells
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The Role of VE-Cadherin in Vascular Morphogenesis and Permeability Control
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Cited by
Passing the Vascular Barrier: Endothelial Signaling Processes Controlling Extravasation
Wettschureck, N., Strilic, B., & Offermanns, S. (2019) · Physiological Reviews · doi:10.1152/physrev.00037.2018 · Cited by 286
Tight Junctions as a Key for Pathogens Invasion in Intestinal Epithelial Cells
Paradis, T., Bègue, H., Basmaciyan, L., Dalle, F., & Bon, F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052506 · Cited by 266
Oxygen Regulation in Development: Lessons from Embryogenesis towards Tissue Engineering
Fathollahipour, S., Patil, P. S., & Leipzig, N. D. (2018) · Cells Tissues Organs · doi:10.1159/000493162 · Cited by 101
Javed, Z., Papageorgiou, M., Madden, L. A., Rigby, A. S., Kilpatrick, E. S., Atkin, S. L., & Sathyapalan, T. (2020) · Endocrine Connections · doi:10.1530/ec-20-0173 · Cited by 24
Metadata
- Authors
- Cerutti, C., & Ridley, A. J.
- Venue
- Experimental Cell Research
- Publisher
- Elsevier BV
- Published
- 2017-09
- Volume
- 358
- Issue
- 1
- Pages
- 31-38
- ISSN
- 0014-4827 (ISSN-L)
- OpenAlex
- W2623250711
- Cited by
- 244
- References
- 6
- FWCI
- 13.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.