The DOI matches its Crossref record; 155 of the 155 references it cites were found in a registry or an index.
Tight Junctions as a Key for Pathogens Invasion in Intestinal Epithelial Cells
Open accessAbstract
Tight junctions play a major role in maintaining the integrity and impermeability of the intestinal barrier. As such, they act as an ideal target for pathogens to promote their translocation through the intestinal mucosa and invade their host. Different strategies are used by pathogens, aimed at directly destabilizing the junctional network or modulating the different signaling pathways involved in the modulation of these junctions. After a brief presentation of the organization and modulation of tight junctions, we provide the state of the art of the molecular mechanisms leading to permeability breakdown of the gut barrier as a consequence of tight junctions’ attack by pathogens, including bacteria, viruses, fungi, and parasites.
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Cites
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Tight junctions: from simple barriers to multifunctional molecular gates
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Capaldo, C. T., & Nusrat, A. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.08.027 · Cited by 718
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
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Junction Adhesion Molecule Is a Receptor for Reovirus
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Cited by
Intestinal Barrier in Human Health and Disease
Di Tommaso, N., Gasbarrini, A., & Ponziani, F. R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312836 · Cited by 533
Gieryńska, M., Szulc-Dąbrowska, L., Struzik, J., Mielcarska, M. B., & Gregorczyk-Zboroch, K. P. (2022) · Animals · doi:10.3390/ani12020145 · Cited by 299
Buchynskyi, M., Kamyshna, I., Halabitska, I., Petakh, P., Kunduzova, O., Oksenych, V., & Kamyshnyi, O. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1577724 · Cited by 30
Metadata
- Authors
- Paradis, T., Bègue, H., Basmaciyan, L., Dalle, F., & Bon, F.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2021-03-02
- Volume
- 22
- Issue
- 5
- Pages
- 2506
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3134851704
- Cited by
- 266
- References
- 155
- FWCI
- 13.26
- Type
- journal article
- Language
- en
- Open access
- gold
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- Paradis, T., Bègue, H., Basmaciyan, L., Dalle, F., & Bon, F. (2021). Tight Junctions as a Key for Pathogens Invasion in Intestinal Epithelial Cells. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22052506
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
