Cited by 391Stress Responses and CortisolMemory and Neural MechanismsNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

Corticosteroid hormones in the central stress response: Quick-and-slow

de Kloet, E. Ronald, Karst, Henk, Joëls, Marian·2008·Frontiers in Neuroendocrinology

DOI 10.1016/j.yfrne.2007.10.002

Open this paper in CoChat — free account

Abstract

Recent evidence shows that corticosteroid hormones exert rapid non-genomic effects on neurons in the hypothalamus and the hippocampal CA1 region. The latter depend on classical mineralocorticoid receptors which are accessible from the outside of the plasma membrane and display a 10-fold lower affinity for corticosterone than the nuclear version involved in neuroprotection. Consequently, this 'membrane' receptor could play an important role while corticosteroid levels are high, i.e. during the initial phase of the stress response. We propose that during this phase corticosterone promotes hippocampal excitability and amplifies the effect of other stress hormones. These permissive non-genomic effects may contribute to fast behavioral effects and encoding of stress-related information. The fast effects are complemented by slower glucocorticoid receptor-mediated effects which facilitate suppression of temporary raised excitability, recovery from the stressful experience and storage of information for future use.

Integrity signals

Registry

Crossref · 10.1016/j.yfrne.2007.10.002

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Physiology and neurobiology of stress and adaptation: central role of the brain
McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429 · cited 1×
“In concert with other stress mediators, the stress-induced rise in glucocorticoid concentration facilitates adaptation to stress and restores homeostasis, (among other things) by enhancing emotional arousal and promoting motivational and cognitive processes [6,17,26].”
Background
Stress and the brain: from adaptation to disease
de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621
Self-citation
Stress and glucocorticoids impair retrieval of long-term spatial memory
de Quervain, D. J.-F., Roozendaal, B., & McGaugh, J. L. (1998) · Nature · doi:10.1038/29542 · Cited by 1,182 · cited 1×
“Moreover, corticosteroid effects were observed on cognitive operations in appraisal of novel situations [29,30], extinction processes [2] and more recently on retrieval processes [7,35].”
Background
Learning under stress: how does it work?
Joëls, M., Pu, Z., Wiegert, O., Oitzl, M. S., & Krugers, H. J. (2006) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.02.002 · Cited by 947
Self-citation
Stress and memory: opposing effects of glucocorticoids on memory consolidation and memory retrieval
Roozendaal, B. (2002) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2002.4080 · Cited by 838
Nongenomic Glucocorticoid Inhibition via Endocannabinoid Release in the Hypothalamus: A Fast Feedback Mechanism
Di, S., Malcher‐Lopes, R., Halmos, K. C., & Tasker, J. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-04850.2003 · Cited by 820
Role of adrenal stress hormones in forming lasting memories in the brain
McGaugh, J. L., & Roozendaal, B. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00306-9 · Cited by 818
Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone
Karst, H., Berger, S., Turiault, M., Tronche, F., Schütz, G., & Joëls, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507572102 · Cited by 774
Self-citation
The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law
Diamond, D. M., Campbell, A. M., Park, C. R., Halonen, J., & Zoladz, P. R. (2007) · Neural Plasticity · doi:10.1155/2007/60803 · Cited by 762 · cited 1×
“It will therefore be very important to also examine rapid effects in other limbic areas important for the central stress response, like amygdalar nuclei or subareas of the prefrontal cortex [10,19,25].”
Background
Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning.
Oitzl, M. S., & de Kloet, E. R. (1992) · Behavioral Neuroscience · doi:10.1037//0735-7044.106.1.62 · Cited by 649

Show all 43 references

Sorted by citations

Items 201–300 of 387

Increased brain glucocorticoid actions following social defeat in rats facilitates the long-term establishment of social subordination
Weger, M., Sevelinges, Y., Grosse, J., de Suduiraut, I. G., Zanoletti, O., & Sandi, C. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.01.008 · Cited by 24
Glucocorticoid exerts its non‐genomic effect on IPSC by activation of a phospholipase C‐dependent pathway in prefrontal cortex of rats
Teng, Z., Zhang, M., Zhao, M., & Zhang, W. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.254961 · Cited by 24
Gene Expression of ACTH, Glucocorticoid Receptors, 11βHSD Enzymes, LH‐, FSH‐, GH Receptors and Aromatase in Equine Epididymal and Testicular Tissue
Herrera-Luna, C. V., Budik, S., & Aurich, C. (2012) · Reproduction in Domestic Animals · doi:10.1111/j.1439-0531.2012.01993.x · Cited by 24
Changes in HPA reactivity and noradrenergic functions regulate spatial memory impairments at delayed time intervals following cerebral ischemia
Milot, M. R., & Plamondon, H. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.02.017 · Cited by 24
Glucocorticoids, Aerobic Physiology, and Locomotor Behavior in California Mice
Dlugosz, E. M., Harris, B. N., Wendy Saltzman, A., & Chappell, M. A. (2012) · Physiological and Biochemical Zoology · doi:10.1086/667809 · Cited by 24
Developmental pathways to attention-deficit/hyperactivity disorder and disruptive behavior disorders: Investigating the impact of the stress response on executive functioning
Johnson, A. C. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.12.001 · Cited by 27
Lasting Impact of Chronic Adolescent Stress and Glucocorticoid Receptor Selective Modulation in Male and Female Rats
Cotella, E. M., Morano, R. L., Wulsin, A. C., Martelle, S. E., Lemen, P. M., Fitzgerald, M. E., Packard, B. A., Moloney, R. D., & Herman, J. P. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104490 · Cited by 22
Dissociated neural effects of cortisol depending on threat escapability
Montoya, E. R., van Honk, J., Bos, P. A., & Terburg, D. (2015) · Human Brain Mapping · doi:10.1002/hbm.22918 · Cited by 24
Low-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats
Gill, D. A., Perry, M. A., McGuire, E. P., Pérez‐Gómez, A., & Tasker, R. A. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.02.036 · Cited by 23
Expression of glucocorticoid and mineralocorticoid receptors in hippocampus of rats exposed to various modes of hypobaric hypoxia: Putative role in hypoxic preconditioning
Rybnikova, E. A., Glushchenko, T., Churilova, A. V., Пивина, С. Г., & Samoilov, M. O. (2011) · Brain Research · doi:10.1016/j.brainres.2011.01.005 · Cited by 22
Peptidergic Edinger–Westphal neurons and the energy-dependent stress response
Xu, L., Scheenen, W. J. J. M., Roubos, E. W., & Kozicz, T. (2011) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2011.11.039 · Cited by 22
The Relationship between Dehydroepiandrosterone (DHEA), Working Memory and Distraction – A Behavioral and Electrophysiological Approach
do Vale, S., Selinger, L., Martins, J. M., Gomes, A. C., Bicho, M., do Carmo, I., & Escera, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104869 · Cited by 24
The CRF1 receptor antagonist SSR125543 prevents stress-induced cognitive deficit associated with hippocampal dysfunction: Comparison with paroxetine and d-cycloserine
Philbert, J., Belzung, C., & Griebel, G. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3020-1 · Cited by 24
A translational approach to clinical practice via stress-responsive glucocorticoid receptor signaling
Juruena, M. F., Agustini, B., Cleare, A. J., & Young, A. H. (2017) · Stem Cell Investigation · doi:10.21037/sci.2017.02.01 · Cited by 20
Early social experience has life-long effects on baseline but not stress-induced cortisol levels in a cooperatively breeding fish
Antunes, D. F., Reyes‐Contreras, M., Glauser, G., & Taborsky, B. (2020) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104910 · Cited by 22
Prenatal Stress and Peripubertal Stimulation of the Endocannabinoid System Differentially Regulate Emotional Responses and Brain Metabolism in Mice
Macrì, S., Ceci, C., Canese, R., & Laviola, G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041821 · Cited by 20
Interindividual and sex differences in resilience and vulnerability to post-traumatic stress disorder (PTSD): insights from animal models
Mancini, G. F., Torrisi, S. A., Viho, E. M. G., Meijer, O. C., Leggio, G. M., & Campolongo, P. (2025) · Biology of Sex Differences · doi:10.1186/s13293-025-00732-5 · Cited by 25
What a difference timing makes: Cortisol effects on neural underpinnings of emotion regulation
Pan, D., Jentsch, V. L., Langer, K., Hagedorn, B., Höffken, O., Wolf, O. T., & Merz, C. J. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100544 · Cited by 23
The Impact of Acute Psychosocial Stress on Magnetoencephalographic Correlates of Emotional Attention and Exogenous Visual Attention
Elling, L., Schupp, H. T., Bayer, J., Bröckelmann, A., Steinberg, C., Dobel, C., & Junghöfer, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035767 · Cited by 23
Genetic variants in serotonin and corticosteroid systems modulate neuroendocrine and cardiovascular responses to intense stress
Taylor, M. K., Larson, G. E., & Lauby, M. D. H. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.004 · Cited by 21
Mineralocorticoid receptors in the ventral tegmental area regulate dopamine efflux in the basolateral amygdala during the expression of conditioned fear
de Oliveira, A. R., Reimer, A. E., & Brandão, M. L. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.02.010 · Cited by 21
Repeated adrenocorticotropic hormone administration alters adrenal and thyroid hormones in free-ranging elephant seals
McCormley, M. C., Champagne, C. D., Deyarmin, J. S., Stephan, A. P., Crocker, D. E., Houser, D. S., & Khudyakov, J. I. (2018) · Conservation Physiology · doi:10.1093/conphys/coy040 · Cited by 20
Inhibition of expression of glucocorticoids receptors may contribute to postpartum depression
Wang, J., Yun, Q., Ma, S.-F., Song, H.-R., Guo, M., & Zhang, W. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.12.040 · Cited by 20
Disrupted upregulation of salience network connectivity during acute stress in siblings of schizophrenia patients
van Leeuwen, J. M. C., Vinkers, C. H., Vink, M., Kahn, R. S., Joëls, M., & Hermans, E. J. (2020) · Psychological Medicine · doi:10.1017/s0033291719004033 · Cited by 21
Self-citation
Programming effects of peripubertal stress on spatial learning
Tzanoulinou, S., Gantelet, E., Sandi, C., & Márquez, C. (2020) · Neurobiology of Stress · doi:10.1016/j.ynstr.2020.100282 · Cited by 20
Maternal Brain Adaptations in Pregnancy
Brunton, P. J., & Russell, J. A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00044-2 · Cited by 18
Nongenomic, glucocorticoid receptor-mediated regulation of serotonin transporter cell surface expression in embryonic stem cell derived serotonergic neurons
Lau, T., Heimann, F., Bartsch, D., Schloss, P. D., & Weber, T. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.08.070 · Cited by 18
High-Fat Feeding Influences the Endocrine Responses of Pubertal Rats to an Acute Stress
Boukouvalas, G., Gerozissis, K., Markaki, E. M., & Kitraki, E. (2010) · Neuroendocrinology · doi:10.1159/000321393 · Cited by 18
Elucidating the Complex Interactions between Stress and Epileptogenic Pathways
Friedman, A. R., Cacheaux, L. P., Ivens, S., & Kaufer, D. (2011) · Cardiovascular Psychiatry and Neurology · doi:10.1155/2011/461263 · Cited by 17
Blood-Brain Barrier Breakdown and Blood-Brain Communication in Neurological and Psychiatric Diseases
Friedman, A., & Kaufer, D. (2011) · Cardiovascular Psychiatry and Neurology · doi:10.1155/2011/431470 · Cited by 18
A Biobehavioral Validation of the Taylor Aggression Paradigm in Female Adolescents
Rinnewitz, L., Parzer, P., Koenig, J., Bertsch, K., Brunner, R. M., Resch, F., & Kaess, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-43456-4 · Cited by 18
Acute restraint stress alters food-foraging behavior in rats: Taking the easier Way while suffered
Tu, B.-X., Wang, L.-F., Zhong, X., Hu, Z., Cao, W.-Y., Cui, Y., Li, S.-J., Zou, G.-J., Liu, Y., Zhou, S.-F., et al. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.04.021 · Cited by 20
Membrane Associated Synaptic Mineralocorticoid and Glucocorticoid Receptors Are Rapid Regulators of Dendritic Spines
Russo, M. F., Loy, S. R. A., Battle, A. R., & Johnson, L. R. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00161 · Cited by 19
[Retracted] Rhodiola Rosea Extract Counteracts Stress in an Adaptogenic Response Curve Manner via Elimination of ROS and Induction of Neurite Outgrowth
Agapouda, A., Grimm, A., Lejri, I., & Eckert, A. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/5647599 · Cited by 16
Retracted
Participation of endocannabinoids in rapid suppression of stress responses by glucocorticoids in neonates
Buwembo, A., Long, H., & Walker, C. D. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.10.057 · Cited by 16
Acute effects of hydrocortisone on the metabolic response to a glucose load: increase in the first-phase insulin secretion
Vila, G., Krebs, M., Riedl, M., Baumgartner-Parzer, S. M., Clodi, M., Maier, C., Pacini, G., & Luger, A. (2010) · European Journal of Endocrinology · doi:10.1530/eje-10-0282 · Cited by 16
Analyzing Stress as a Multivariate Phenotype
Telemeco, R. S., & Gangloff, E. J. (2020) · Integrative and Comparative Biology · doi:10.1093/icb/icaa005 · Cited by 16
Possible antidepressant mechanism of acupuncture: targeting neuroplasticity
Xu, N., He, Y., Wei, Y.-N., Bai, L., & Wang, L. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1512073 · Cited by 20
A proposed role for glucocorticoids in mediating dopamine-dependent cue-reward learning
Lopez, S. A., & Flagel, S. B. (2020) · Stress · doi:10.1080/10253890.2020.1768240 · Cited by 16
Phenotypically driven subgroups of ASD display distinct metabolomic profiles
Prince, N., Chu, S. H., Chen, Y., Mendez, K. M., Hanson, E. M., Green‐Snyder, L., Brooks, E. A., Korrick, S., Lasky-Su, J. A., & Kelly, R. S. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.03.026 · Cited by 14
Defensive coping and renovascular disease risk — Adrenal fatigue in a cohort of Africans and Caucasians: The SABPA study
de Kock, A., Malan, L., Hamer, M., Cockeran, M., & Malan, N. T. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.04.033 · Cited by 14
The Hippocampus as a Neural Link between Negative Affect and Vulnerability for Psychostimulant Relapse
Barr, J. L., Bray, B., & Forster, G. L. (2018) · InTech eBooks · doi:10.5772/intechopen.70854 · Cited by 13
Inflammatory responses associated with hyposaline stress in gill epithelial cells of the spotted scat Scatophagus argus
Zhong, Y., Duan, Z., Su, M., Lin, Y., & Zhang, J. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.04.023 · Cited by 14
Self‐Regulation and Developmental Psychopathology: Experiential Canalization of Brain and Behavior
Blair, C., Raver, C. C., & Finegood, E. D. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy213 · Cited by 16
Stress Detection During Motor Activity: Comparing Neurophysiological Indices in Older Adults
Karthikeyan, R., McDonald, A. D., & Mehta, R. K. (2022) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2022.3148234 · Cited by 15
Stress increases sperm respiration and motility in mice and men
Moon, N., Morgan, C. P., Marx-Rattner, R., Jeng, A., Johnson, R. L., Chikezie, I., Mannella, C. A., Sammel, M. D., Epperson, C. N., & Bale, T. L. (2024) · Nature Communications · doi:10.1038/s41467-024-52319-0 · Cited by 15
Prenatal Hypoxia-Induced Adverse Reaction to Mild Stress is Associated with Depressive-Like Changes in the Glucocorticoid System of Rats
Vetrovoy, O. V., Stratilov, V. A., Lomert, E. V., & Tyulkova, E. I. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03837-0 · Cited by 13
Stress-evoked increases in serotonin in the auditory midbrain do not directly result from elevations in serum corticosterone
Hall, I. C., Sell, G. L., Chester, E. M., & Hurley, L. M. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.08.042 · Cited by 13
Neuroendocrine responses in neonatal mother-deprived rabbits
Brecchia, G., Bonanno, A., Dall'Aglio, C., Mercati, F., Zerani, M., Grigoli, A. D., & Boiti, C. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.057 · Cited by 13
MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors
Tanaka, T., Shimizu, S., Ueno, M., Fujihara, Y., Ikawa, M., & Miyata, S. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.03.018 · Cited by 12
Corticosterone regulates fear memory via Rac1 activity in the hippocampus
Gan, P., Ding, Z.-Y., Gan, C., Mao, R., Zhou, H., Xu, L., & Zhou, Q. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.05.011 · Cited by 14
Neuroactive Steroids in Acute Ischemic Stroke: Association with Cognitive, Functional, and Neurological Outcomes
Casas, S., Deniselle, M. C. G., Gargiulo-Monachelli, G. M., Perez, A., Tourreilles, M., Mattiazzi, M., Ojeda, C., Polesel, D. L., & Nicola, A. F. D. (2016) · Hormone and Metabolic Research · doi:10.1055/s-0042-119201 · Cited by 13
Stress-induced cortisol is associated with generation of non-negative interpretations during cognitive reappraisal
Tsumura, H., Sensaki, J., & Shimada, H. (2015) · BioPsychoSocial Medicine · doi:10.1186/s13030-015-0049-x · Cited by 12
The role of neuroactive steroids in psychiatric and neurological disorders: Neurobiology and therapeutic perspectives
Pinna, G., & Bortolato, M. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106438 · Cited by 12
Cortisol rapidly increases baroreflex sensitivity of heart rate control, but does not affect cardiac modulation of startle
Schulz, A., Richter, S., de Sá, D. S. F., Vögele, C., & Schächinger, H. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112792 · Cited by 13
Corticosteroid responses following hypoxic preconditioning provide neuroprotection against subsequent hypoxic‐ischemic brain injury in the newborn rats
Feng, Y., & Bhatt, A. (2015) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2015.04.010 · Cited by 11
Gynostemmaï¿½pentaphyllum is neuroprotective in a rat model of cardiopulmonary resuscitation
Keilhoff, G., Esser, T., Titze, M., Ebmeyer, U., & Schild, L. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5315 · Cited by 11
Acute stress enhances pupillary responses to erotic nudes: Evidence for differential effects of sympathetic activation and cortisol
Finke, J. B., Behrje, A., & Schächinger, H. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2018.07.005 · Cited by 13
Brain Mineralocorticoid Receptors and Resilience to Stress
Kanatsou, S., Joëls, M., & Krugers, H. J. (2018) · Vitamins and hormones · doi:10.1016/bs.vh.2018.11.001 · Cited by 14
Self-citation
Intrahypothalamic effects of oxytocin on PVN CRH neurons in response to acute stress
Pati, D., Krause, E. G., & Frazier, C. J. (2022) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2022.100382 · Cited by 10
Expression of 11β‐Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptors in Reproductive Tissue of Male Horses at Different Stages of Sexual Maturity
Herrera-Luna, C. V., Budik, S., Helmreich, M., Walter, I., & Aurich, C. (2012) · Reproduction in Domestic Animals · doi:10.1111/j.1439-0531.2012.02137.x · Cited by 10
Distinct Amygdalar AMPAergic/GABAergic Mechanisms Promote Anxiolitic-Like Effects in an Unpredictable Stress Model of the Hamster
Alò, R., Mele, M., Avolio, E., Fazzari, G., & Canonaco, M. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0386-4 · Cited by 10
The role of hormones in the pathogenesis and treatment mechanisms of delirium in ICU: The past, the present, and the future
Cao, Y., Song, Y., Ding, Y., Ni, J., Zhu, B., Shen, J., & Miao, L. (2023) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2023.106356 · Cited by 10
Association of violence with urban points of interest
Redfern, J., Sidorov, K. A., Rosin, P. L., Corcoran, P., Moore, S., & Marshall, D. (2020) · PLoS ONE · doi:10.1371/journal.pone.0239840 · Cited by 11
Anesthesia can alter the levels of corticosterone and the phosphorylation of signaling molecules
Pereira, G. C., Mônico‐Neto, M., Antunes, H. K. M., Lee, K. S., & da Luz, M. H. M. (2021) · BMC Research Notes · doi:10.1186/s13104-021-05763-w · Cited by 10
Fat Feeding of Rats During Pubertal Growth Leads to Neuroendocrine Alterations in Adulthood
Boukouvalas, G., Gerozissis, K., & Kitraki, E. (2009) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-009-9434-y · Cited by 10
Role of nitric oxide on purinergic signalling in the cochlea
Harada, N. (2010) · Purinergic Signalling · doi:10.1007/s11302-010-9186-7 · Cited by 10
The insula mediates the effects of glucocorticoids in anxiety
Bahamonde, T., Quintana-Donoso, D., Linsambarth, S., Jerez-Baraona, J. M., Peña, F., Tamburini, G., Verdugo, D. A., Lemunao-Inostroza, Y., Ogaz, F., Díaz-Galarce, R., et al. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109620 · Cited by 9
The relationship between family function and the incidence of overweight/obesity in children and adolescents in Chengdu city, Sichuan province of China: based on latent profile analysis
Jiang, X., Zhao, X., Zhou, J., Zhang, X., Song, Y., & Zhao, L. (2023) · BMC Public Health · doi:10.1186/s12889-023-17143-z · Cited by 9
Molecular and functional mapping of the neuroendocrine hypothalamus: a new era begins
Lee, T. H., Nicolas, J.-C., & Quarta, C. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-024-02411-5 · Cited by 12
Neurobiología del estrés agudo y crónico: su efecto en el eje hipotálamohipófisis- adrenal y la memoria
Rodríguez-Fernández, J. M., García-Acero, M., & Franco, P. (2013) · Universitas Médica · doi:10.11144/javeriana.umed54-4.neac · Cited by 9
Individual and interactive sex-specific effects of acute restraint and systemic IFN-γ treatment on neurochemistry
Litteljohn, D., Rudyk, C., Razmjou, S., Dwyer, Z., Syed, S., & Hayley, S. P. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.11.005 · Cited by 9
Biological Pathways to Stress-Related Disease Vulnerability in Educators
Bellingrath, S., & Kudielka, B. M. (2017) · Aligning perspectives on health, safety and well-being · doi:10.1007/978-3-319-53053-6_4 · Cited by 10
Prenatal Stress as a Factor of the Development of Addictive States
Stratilov, V. A., Tyulkova, E. I., & Vetrovoy, O. V. (2020) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093020060010 · Cited by 9
Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress
Harada, H., Mori, M., Murata, Y., Kawanabe, S., Terada, K., Matsumoto, T., Ohe, K., & Enjoji, M. (2023) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2202043 · Cited by 9
Adult Consequences of Post-weaning High Fat Feeding on the Limbic—HPA Axis of Female Rats
Boukouvalas, G., Gerozissis, K., & Kitraki, E. (2009) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-009-9476-1 · Cited by 8
Role of oxidative stress in disrupting the function of negative glucocorticoid response element in daily amphetamine-treated rats
Chu, S., Yu, C., Chen, P., Hsieh, Y., & Kuo, D. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.04.025 · Cited by 8
Effects of Adrenalectomy on Neuronal Substrate Fuel Transporter and Energy Transducer Gene Expression in Hypothalamic and Hindbrain Metabolic Monitoring Sites
Cherian, A. K., & Briski, K. P. (2009) · Neuroendocrinology · doi:10.1159/000264919 · Cited by 8
Gender dependent contribution of muscarinic receptors in memory retrieval under sub-chronic stress
Rashid, H., & Ahmed, T. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.05.024 · Cited by 8
Stress, Corticosterone, and Hippocampal Plasticity
Maggio, N., & Segal, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813146-6.00008-4 · Cited by 7
Glucocorticoid Receptor in Health and Disease
Dundjerski, J., & Matić, G. M. (2009) · Journal of Medical Biochemistry · doi:10.2478/v10011-009-0022-y · Cited by 7
Effect of acute heat stress on cognitive performance of chickens in a feed-related discriminant task
Iyasere, O. S., Oyetunji, D. E., Wheto, M., Durosaro, S. O., Adigun, T. T., Muraina, H. A., Akinyemi, O. O., & Daramola, J. O. (2021) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2021.102914 · Cited by 7
An Advanced Transcriptional Response to Corticosterone After Single Prolonged Stress in Male Rats
Ding, J., Chen, X., Han, F., & Meijer, O. C. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.756903 · Cited by 7
Two-year course of non-suicidal self-injury in an adolescent clinical cohort: The role of childhood adversity in interaction with cortisol secretion
Reichl, C., Schär, S., Lerch, S., Hedinger, N., Brunner, R. M., Koenig, J., & Kaess, M. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107093 · Cited by 6
Stress effects on the top-down control of visuospatial attention: Evidence from cue-dependent alpha oscillations
Larra, M. F., Zhang, X., Finke, J. B., Schächinger, H., Wascher, E., & Arnau, S. (2022) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-022-00994-1 · Cited by 7
Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology
Цейликман, В. Э., Евгеньевич, А. А., Shevelev, O. B., Khotskina, А. S., Kontsevaya, G. V., Moshkin, M. P., Fedotova, J., Pashkov, A. A., Tseilikman, O. B., Agletdinov, E. F., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169151 · Cited by 6
Summarizing studies using constitutive genetic deficiency to investigate behavioural influences of uptake 2 monoamine transporters
Weber, B. L., Beaver, J. N., & Gilman, T. L. (2022) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13810 · Cited by 6
Non-genomic action of beclomethasone dipropionate on bronchoconstriction caused by leukotriene C4 in precision cut lung slices in the horse
Fugazzola, M. C., Barton, A. K., Niedorf, F., Kietzmann, M., & Ohnesorge, B. (2012) · BMC Veterinary Research · doi:10.1186/1746-6148-8-160 · Cited by 6
Chronic systemic administration of serotonergic ligands flibanserin and 8-OH-DPAT enhance HPA axis responses to restraint in female marmosets
Aubert, Y., Bohl, M. A., Lange, J. R., Diol, N. R., Allers, K. A., Sommer, B., Datson, N. A., & Abbott, D. H. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.05.011 · Cited by 6
[Intrauterine stress impairs spatial learning in the progeny of Wistar rats].
González-Pérez, Ó., Gutiérrez-Smith, Y., Guzmán‐Muñiz, J., & López, N. A. M. (2011) · PubMed · Cited by 6
Pharmacological Suppression of Endogenous Glucocorticoid Synthesis Attenuated Blood Pressure and Heart Rate Response to Acute Restraint in Wistar Rats
Bencze, M., Vavřínová, A., Zicha, J., & Behuliak, M. (2020) · Physiological Research · doi:10.33549/physiolres.934432 · Cited by 6
Corticosteroid-binding-globulin (CBG)-deficient mice show high pY216-GSK3β and phosphorylated-Tau levels in the hippocampus
Gulfo, J., Román, J. P. D. S., Ledda, A., Junyent, F., Ramírez, M. J., Gil-Bea, F. J., Esteve, M., & Grasa, M. (2021) · PLoS ONE · doi:10.1371/journal.pone.0246930 · Cited by 6
Litter characteristics and helping context during early life shape the responsiveness of the stress axis in a wild cooperative breeder
Cohas, A., Bichet, C., Garcia, R., Pardonnet, S., Lardy, S., & Rey, B. (2021) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-021-03108-y · Cited by 6
The effects of cortisol on emotion
Sudheimer, K. D. (2009) · Deep Blue (University of Michigan) · Cited by 6
Immediate and Delayed Salivary Cytokine Responses during Repeated Exposures to Cold Pressor Stress
Larra, M. F., Capellino, S., Schwendich, E., von Haugwitz, L., Reinders, J., & Wascher, E. (2023) · NeuroImmunoModulation · doi:10.1159/000529625 · Cited by 6
Early positive tactile stimulation reverses the increase of anxiety and decrease of sociality induced by early chronic mechanical pain in mandarin voles
Sun, Y., Xiao, J., Luoman, L. I., Niu, H., Yiting, Z. H. U., Li, L., Qian, W., Yin, L. I., Zhang, L., Qu, Y., et al. (2024) · Integrative Zoology · doi:10.1111/1749-4877.12907 · Cited by 4
Pränatale Entwicklung und neurobiologische Grundlagen der psychischen Entwicklung
Roth, G., & Strüber, N. (2011) · Springer eBooks · doi:10.1007/978-3-642-20296-4_1 · Cited by 5
Endocannabinoid Signaling and Synaptic Plasticity During Stress
Gray, J. M., Vecchiarelli, H. A., & Hill, M. N. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1056-4_6 · Cited by 5
Somatic Health Issues in Trauma-Related Disorders: Effects on Psychobiological Axes Affecting Mental and Physical Health
King, A. P. J. (2018) · Integrating psychiatry and primary care · doi:10.1007/978-3-319-74736-1_10 · Cited by 6
BPA Effects In Vivo: Evidence from Animal Studies
Kitraki, E. (2013) · Springer eBooks · doi:10.1007/978-3-642-29687-1_4 · Cited by 5

Authors: de Kloet, E. R., Karst, H., & Joëls, M.
Affiliations: Leiden University Medical Center (NL)
University of Amsterdam (NL)
ORCID: de Kloet, E. Ronald
Karst, Henk
Joëls, Marian
Venue: Frontiers in Neuroendocrinology
Publisher: Elsevier BV
Published: 2008-05
Volume: 29
Issue: 2
Pages: 268-272
ISSN: 0091-3022 (ISSN-L)
DOI: 10.1016/j.yfrne.2007.10.002
OpenAlex: W2137942121
Cited by: 391
References: 43
Citations by year: 2026: 6 · 2025: 9 · 2024: 7 · 2023: 11 · 2022: 17 · 2021: 16 · 2020: 21 · 2019: 14 · 2018: 25 · 2017: 17 · 2016: 27 · 2015: 23 · 2014: 38 · 2013: 22 · 2012: 31
FWCI: 1.59
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Frontiers in Neuroendocrinology (publishedVersion)
PubMed (publishedVersion)
UvA-DARE (University of Amsterdam) (submittedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: corticosteroids, non-genomic steroid effects, glucocorticoid receptor, hypothalamus, hippocampal CA1, hippocampal excitability, stress response, corticosterone, neuroprotection
MeSH terms: Adrenal Cortex Hormones, Animals, Hippocampus, Humans, Hypothalamus, Neurons, Receptors, Glucocorticoid, Stress, Physiological, Time Factors, Genome, Receptors, Mineralocorticoid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Corticosteroid hormones in the central stress response: Quick-and-slow

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks