Gonadotrophin-releasing hormone in winter flounder (Pseudopleuronectes americanus): Molecular characterization, distribution and effects of fasting

Tuziak, Sarah M.; Volkoff, Hélène

doi:10.1016/j.ygcen.2012.12.010

Cited by 20Hypothalamic control of reproductive hormonesReproductive biology and impacts on aquatic speciesNeuropeptides and Animal Physiology

Gonadotrophin-releasing hormone in winter flounder (Pseudopleuronectes americanus): Molecular characterization, distribution and effects of fasting

Tuziak, Sarah M., Volkoff, Hélène·2013·General and Comparative Endocrinology

DOI 10.1016/j.ygcen.2012.12.010

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Abstract

Gonadotrophin-releasing hormone (GnRH) is primarily related to reproductive processes in vertebrates. However other physiological roles, including functions in food intake regulation and energy status, have been demonstrated for GnRH in animals. The ten amino acid active peptide is relatively conserved throughout chordates, more specifically in fish species. Teleosts generally have at least two variants of GnRH present in their genomes. GnRH2 (commonly termed chicken-GnRH) is common to all fish, whereas other prevalent forms include GnRH1 and/or GnRH3 (also known as salmon-GnRH). The mRNAs of all three forms were identified in winter flounder (Pseudopleuronectes americanus). Winter flounder GnRH1 appears to be ubiquitously and strongly expressed throughout the brain. GnRH2 mRNA is highly expressed in the optic tectum/thalamus. Finally, GnRH3 mRNA is expressed throughout the brain, but not in the pituitary, with apparent highest expression in the telencephalon/preoptic area. Flounder GnRH1 mRNA is found in most peripheral tissues examined, including the foregut, midgut and gonads. GnRH2 mRNA appears to be expressed throughout the periphery, with apparent highest transcript expression in male gonads. Finally, winter flounder GnRH3 transcript is found at low levels in the skin, heart, and gonads. The effect of fasting on the expression of each of the three isoforms was assessed. Fasting reduces GnRH2 and GnRH3 mRNA expression in the optic tectum/thalamus and hypothalamus, and telencephalon/preoptic area, respectively, compared with fed fish. GnRH1 mRNA expression does not appear to be altered by feeding status. GnRH mRNAs do not seem to regulate food intake peripherally through the gut based on our preliminary findings. Our preliminary results suggest that the GnRH system could play a central role in food intake regulation of winter flounder.

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Gnrh genes are down-regulated in animals exposed to fasting or food restriction.
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MUSCLE: multiple sequence alignment with high accuracy and high throughput
Edgar, R. C. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh340 · Cited by 44,662 · see citing works
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Tamura, K., Dudley, J. T., Nei, M., & Kumar, S. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm092 · Cited by 28,734 · see citing works
OligoCalc: an online oligonucleotide properties calculator
Kibbe, W. A. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm234 · Cited by 1,300 · see citing works
Neuroendocrinology of reproduction in teleost fish
Zohar, Y., Muñoz‐Cueto, J. A., Elizur, A., & Kah, O. (2009) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2009.04.017 · Cited by 892 · see citing works
Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species.
Miyamoto, K., Hasegawa, Y., Nomura, M., Igarashi, M., Kangawa, K., & Matsuo, H. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.12.3874 · Cited by 457 · see citing works
Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat.
Adelman, J. P., Mason, A. J., Hayflick, J. S., et al. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.1.179 · Cited by 354 · see citing works
Gonadotropin-Releasing Hormone Genes: Phylogeny, Structure, and Functions
Fernald, R. D., & White, R. B. (1999) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1999.0181 · Cited by 298 · see citing works
Structural and functional evolution of gonadotropin‐releasing hormone in vertebrates
Okubo, K., & Nagahama, Y. (2008) · Acta Physiologica · doi:10.1111/j.1748-1716.2008.01832.x · Cited by 271 · see citing works
Structure of chicken hypothalamic luteinizing hormone-releasing hormone. II. Isolation and characterization.
King, J. A., & Millar, R. P. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33883-3 · Cited by 230 · see citing works
Structure of chicken hypothalamic luteinizing hormone-releasing hormone. I. Structural determination on partially purified material.
King, J. A., & Millar, R. P. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33882-1 · Cited by 220 · see citing works
The telencephalon and hypothalamus of the bluegill (Lepomis macrochirus): Evoked feeding, aggressive and reproductive behavior with representative frontal sections
Demski, L. S., & Knigge, K. M. (1971) · The Journal of Comparative Neurology · doi:10.1002/cne.901430102 · Cited by 205 · see citing works
Evolutionary aspects of gonadotropin-releasing hormone and its receptor
King, J. A., & Millar, R. P. (1995) · Cellular and Molecular Neurobiology · doi:10.1007/bf02069556 · Cited by 177 · see citing works
Three Forms of Gonadotropin-Releasing Hormone in a Perciform Fish (Sparus Aurata): Complementary Deoxyribonucleic Acid Characterization and Brain Localization1
Gothilf, Y., Muñoz‐Cueto, J. A., Sagrillo, C. A., et al. (1996) · Biology of Reproduction · doi:10.1095/biolreprod55.3.636 · Cited by 172 · see citing works
Immunohistochemical localization of three different prepro‐GnRHs in the brain and pituitary of the European sea bass (Dicentrarchus labrax) using antibodies to the corresponding GnRH‐associated peptides
González-Martı́nez, D., Zmora, N., Mañanós, E. L., Saligaut, D., Zanuy, S., Zohar, Y., Elizur, A., Kah, O., & Muñoz‐Cueto, J. A. (2002) · The Journal of Comparative Neurology · doi:10.1002/cne.10190 · Cited by 148 · see citing works
Origins of Gonadotropin-Releasing Hormone (GnRH) in Vertebrates: Identification of a Novel GnRH in a Basal Vertebrate, the Sea Lamprey
Kavanaugh, S. I., Nozaki, M., & Sower, S. A. (2008) · Endocrinology · doi:10.1210/en.2008-0184 · Cited by 129 · see citing works
Multiple gonadotropin‐releasing hormone (GnRH)‐immunoreactive systems in the brain of the dwarf gourami,Colisa lalia: Immunohistochemistry and radioimmunoassay
Yamamoto, N., Oka, Y., Amano, M., et al. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903550303 · Cited by 122 · see citing works
A Novel Form of Gonadotropin-Releasing Hormone in the Medaka, Oryzias latipes
Okubo, K., Amano, M., Yoshiura, Y., et al. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3476 · Cited by 114 · see citing works
Presence and Differential Distribution of Distinct Forms of Immunoreactive Gonadotropin-Releasing Hormone in the Musk Shrew Brain
Dellovade, T., King, J. A., Millar, R. P., et al. (2008) · Neuroendocrinology · doi:10.1159/000126529 · Cited by 106 · see citing works
Inhibitory effect of chicken gonadotropin-releasing hormone II on food intake in the goldfish, Carassius auratus
Matsuda, K., Nakamura, K., Shimakura, S.-I., Miura, T., Kageyama, H., Uchiyama, M., Shioda, S., & Ando, H. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.01.011 · Cited by 96 · see citing works
Evidence that chicken hypothalamic luteinizing hormone- releasing hormone is [Gln8]-LHRH
Miyamoto, K., Hasegawa, Y., Igarashi, M., et al. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90808-1 · Cited by 96 · see citing works
Interactions between gonadotropin-releasing hormone (GnRH) and orexin in the regulation of feeding and reproduction in goldfish (Carassius auratus)
Hoskins, L. J., Xu, M., & Volkoff, H. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.04.011 · Cited by 94 · see citing works
Self-citation
Effects of photoperiod on sexual maturation and somatic growth in male Atlantic halibut (Hippoglossus hippoglossus L.)
Norberg, B., Weltzien, F., Karlsen, Ø., et al. (2001) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(01)00320-7 · Cited by 92 · see citing works
Brain distribution of radioimmunoassayable gonadotropin-releasing hormone in female goldfish: Seasonal variation and periovulatory changes
Yu, K. L., Nahorniak, C. S., Peter, R. E., et al. (1987) · General and Comparative Endocrinology · doi:10.1016/0016-6480(87)90153-5 · Cited by 87 · see citing works
GnRH and GnRH receptors: distribution, function and evolution
Chen, C., & Fernald, R. D. (2008) · Journal of Fish Biology · doi:10.1111/j.1095-8649.2008.01936.x · Cited by 86 · see citing works
Two gonadotropin-releasing hormones in the African catfish, Clarias gariepinus: localization, pituitary receptor binding, and gonadotropin release activity
Schulz, R. W., Bosma, P. T., Zandbergen, M. A., der Sanden, M. C. V., van Dijk, W., Peute, J., Bogerd, J., & Goos, H. J. T. (1993) · Endocrinology · doi:10.1210/endo.133.4.8404596 · Cited by 78 · see citing works
Two molecular forms of gonadotropin-releasing hormone from the brain of the frog, Rana ribibunda: purification, characterization, and distribution
Conlon, J. M., Collin, F. X. E. O., Chiang, Y. C., Sower, S. A., & Vaudry, H. (1993) · Endocrinology · doi:10.1210/endo.132.5.8477660 · Cited by 78 · see citing works
The Evolutionarily Conserved Gonadotropin-Releasing Hormone II Modifies Food Intake
Kauffman, A. S., & Rissman, E. F. (2003) · Endocrinology · doi:10.1210/en.2003-1150 · Cited by 76 · see citing works
Comparative distribution of mammalian GnRH (gonadotrophin‐releasing hormone) and chicken GnRH‐II in the brain of the immature siberian sturgeon (Acipenser baeri)
Leprêtre, E., Anglade, I., Williot, P., et al. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903370404 · Cited by 75 · see citing works
The Brain and Feeding Behavior* *The unpublished results reported were supported by a grant from the National Research Council of Canada to the author.
Peter, R. E. (1979) · Fish physiology · doi:10.1016/s1546-5098(08)60026-6 · Cited by 70 · see citing works
Food deprivation explains effects of mouthbrooding on ovaries and steroid hormones, but not brain neuropeptide and receptor mRNAs, in an African cichlid fish
Grone, B. P., Carpenter, R. E., Lee, M., Maruska, K. P., & Fernald, R. D. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.04.012 · Cited by 70 · see citing works
Isolation, characterization and expression of cDNAs encoding the catfish‐type and chicken‐II‐type gonadotropin‐releasing‐hormone precursors in the African catfish
Bogerd, J., Zandbergen, T., Andersson, E., et al. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb18896.x · Cited by 69 · see citing works
Distribution of Variant Forms of Immunoreactive Gonadotropin-Releasing Hormone and β-Gonadotropins I and II in the Platyfish, Xiphophorus maculatus, from Birth to Sexual Maturity
Magliulo-Cepriano, L., Schreibman, M. P., & Blüm, V. (1994) · General and Comparative Endocrinology · doi:10.1006/gcen.1994.1067 · Cited by 65 · see citing works
Three GnRH systems in the brain and pituitary of a pleuronectiform fish, the barfin flounder Verasper moseri
Amano, M., Oka, Y., Yamanome, T., et al. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0594-z · Cited by 64 · see citing works
Multiple molecular forms of gonadotropin-releasing hormone in teleost fish brain
King, J. A., & Millar, R. P. (1985) · Peptides · doi:10.1016/0196-9781(85)90173-1 · Cited by 58 · see citing works
Chromosomal Organization, Evolutionary Relationship, and Expression of Zebrafish GnRH Family Members
Kuo, M., Lou, S.-W., Postlethwait, J. H., & Chung, B. (2005) · Journal of Biomedical Science · doi:10.1007/s11373-005-7457-z · Cited by 55 · see citing works
The frog gonadotropin-releasing hormone-I (GnRH-I) gene has a mammalian- like expression pattern and conserved domains in GnRH-associated peptide, but brain onset is delayed until metamorphosis
Hayes, W. P., Wray, S., & Battey, J. F. (1994) · Endocrinology · doi:10.1210/endo.134.4.8137750 · Cited by 54 · see citing works
Induced spawning of catfish, Heteropneustes fossilis (Bloch), using d-Lys6 salmon gonadotropin-releasing hormone analog
Deoraj, A., Krishnan, T. S., Talwar, G. P., et al. (1993) · Aquaculture · doi:10.1016/0044-8486(93)90366-7 · Cited by 51 · see citing works
Isolation, cloning, and expression of three prepro‐GnRH mRNAs in Atlantic croaker brain and pituitary
Mohamed, J. S., Thomas, P., & Khan, I. A. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20596 · Cited by 50 · see citing works
Expression of Two Gonadotropin-Releasing Hormone (GnRH) Precursor Genes in Various Tissues of the Japanese Eel and Evolution of GnRH
Okubo, K., Suetake, H., & Aida, K. (1999) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.16.471 · Cited by 50 · see citing works
Gonadotropin-releasing hormone-immunoreactive neuronal structures in the brain and pituitary of the African catfish, Clarias gariepinus (Burchell)
Goos, H. J. T., Leeuw, R. D., de Zoeten-Kamp, C., Peute, J., & Blähser, S. (1985) · Cell and Tissue Research · doi:10.1007/bf00214580 · Cited by 46 · see citing works
Characterization of the cDNAs Encoding Three GnRH Forms in the Pejerrey Fish Odontesthes bonariensis (Atheriniformes) and the Evolution of GnRH Precursors
Guilgur, L. G., Ortı́, G., Strobl‐Mazzulla, P. H., Fernandino, J. I., Miranda, L. A., & Somoza, G. M. (2007) · Journal of Molecular Evolution · doi:10.1007/s00239-006-0125-8 · Cited by 44 · see citing works
Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish
Hildahl, J., Sandvik, G. K., Edvardsen, R. B., et al. (2011) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2011.04.010 · Cited by 44 · see citing works
Localization of salmon gonadotropin‐releasing hormone mRNA and peptide in the brain of atlantic salmon and rainbow trout
Bailhache, T., Arazam, A., Klungland, H., et al. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903470310 · Cited by 43 · see citing works
Chicken GnRH II occurs together with mammalian GnRH in a South American species of marsupial (Monodelphis domestica)
King, J. A., Hinds, L. A., MEHL, A. E. I., et al. (1990) · Peptides · doi:10.1016/0196-9781(90)90053-8 · Cited by 42 · see citing works
Gonadotropin-Releasing Hormone-II Messenger Ribonucleic Acid and Protein Content in the Mammalian Brain Are Modulated by Food Intake
Kauffman, A. S., Bojkowska, K., Wills, A., & Rissman, E. F. (2006) · Endocrinology · doi:10.1210/en.2006-0615 · Cited by 42 · see citing works
The Effect of Food Intake from 2 to 24 Weeks of Age on LHRH-I Content in the Median Eminence and Gonadotrophin Levels in Pituitary and Plasma in Female Broiler Breeder Chickens
Bruggeman, V., Dhondt, E., Berghman, L., et al. (1998) · General and Comparative Endocrinology · doi:10.1006/gcen.1998.7165 · Cited by 39 · see citing works
Cultured pituitary cell GtH response to GnRH at different stages of rainbow trout oogenesis and influence of steroid hormones
Weil, C., & Marcuzzi, O. (1990) · General and Comparative Endocrinology · doi:10.1016/0016-6480(90)90079-2 · Cited by 37 · see citing works
Induced spawning of maturing milkfish (Chanos chanos Forsskal) with gonadotropin-releasing hormone (GnRH) analogues administered in various ways
Marte, C. L., Sherwood, N. M., Crim, L. W., et al. (1987) · Aquaculture · doi:10.1016/0044-8486(87)90295-x · Cited by 36 · see citing works
Differential regional distribution of gonadotropin-releasing hormones in amphibian (clawed toad, Xenopus laevis) brain
King, J. A., Steneveld, A. A., & Millar, R. P. (1994) · Regulatory Peptides · doi:10.1016/0167-0115(94)90008-6 · Cited by 35 · see citing works
Immunological Characterization and Distribution of Three GnRH Forms in the Brain and Pituitary Gland of Chub Mackerel (Scomber japonicus)
Selvaraj, S., Kitano, H., Fujinaga, Y., et al. (2009) · ZOOLOGICAL SCIENCE · doi:10.2108/zsj.26.828 · Cited by 35 · see citing works
The Population of GnRH-Containing Neurons Showing Socially Mediated Size Changes Project to the Pituitary in a Teleost, Hapiochromis burtoni
Bushnik, T., & Fernald, R. D. (2008) · Brain Behavior and Evolution · doi:10.1159/000113287 · Cited by 33 · see citing works
Identification and characterization of the reptilian GnRH-II gene in the leopard gecko, Eublepharis macularius, and its evolutionary considerations
Ikemoto, T., & Park, M. K. (2003) · Gene · doi:10.1016/s0378-1119(03)00758-3 · Cited by 31 · see citing works
Effects of Photoperiod on Salmon GnRH mRNA Levels in Brain of Castrated Underyearling Precocious Male Masu Salmon
Amano, M., Ikuta, K., Kitamura, S., et al. (1999) · General and Comparative Endocrinology · doi:10.1006/gcen.1999.7286 · Cited by 30 · see citing works
A new member of the gonadotropin-releasing hormone family in teleosts: Catfish gonadotropin-releasing hormone
Sherwood, N. M., Leeuw, R. D., & Goos, H. J. T. (1989) · General and Comparative Endocrinology · doi:10.1016/0016-6480(89)90178-0 · Cited by 30 · see citing works
A comparative study of the brains in pleuronectidae
Evans, H. M. (1937) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1937.0027 · Cited by 30 · see citing works
Localization and characterization of gonadotropin-releasing hormones in the brain, gonads, and plasma of a dipnoi (lungfish, Protopterus annectens)
King, J. A., Millar, R. P., Vallarino, M., et al. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00025-7 · Cited by 26 · see citing works
Distribution of salmon gonadotrophin releasing-hormone in the brain and pituitary of the sea bass (Dicentrarchus labrax)
Kah, O., Zanuy, S., Ma�anos, E., et al. (1991) · Cell and Tissue Research · doi:10.1007/bf00678719 · Cited by 26 · see citing works
Presence and distribution of radioimmunoassayable LHRH in the european eel, Anguilla anguilla
Dufour, S., Pasqualini, C., Kerdelhué, B., et al. (1982) · Neuropeptides · doi:10.1016/0143-4179(82)90011-7 · Cited by 25 · see citing works
Identification of Gln8-GnRH and His5,Trp7,Tyr8-GnRH in the hypothalamus and extrahypothalamic brain of the ostrich (Struthio camelus).
Powell, R. C., Jach, H., Millar, R., & King, J. A. (1987) · Peptides · doi:10.1016/0196-9781(87)90185-9 · Cited by 22 · see citing works
Immunocytochemical localization of GnRH (gonadotropin releasing hormone) systems in the brain of a marine teleost fish, the sole
Rodrìguez, J. N., Kah, O., Breton, B., et al. (1985) · Cellular and Molecular Life Sciences · doi:10.1007/bf01964814 · Cited by 22 · see citing works
Immunoreactive Gonadotropin-Releasing Hormone (GnRH) Is Detected Only in the Form of Chicken GnRH-II within the Brain of the Green Anole,Anolis carolinensis
Lescheid, D. W., Rosen, G. J., Bridge, A. E. A., et al. (1997) · General and Comparative Endocrinology · doi:10.1006/gcen.1997.6970 · Cited by 21 · see citing works
Acute Re-Feeding Reverses Food Restriction-Induced Hypothalamic-Pituitary-Gonadal Axis Deficits1
Temple, J. L., & Rissman, E. F. (2000) · Biology of Reproduction · doi:10.1095/biolreprod63.6.1721 · Cited by 21 · see citing works
Cultured pituitary cell GtH response to GnRH at different stages of rainbow trout spermatogenesis and influence of steroid hormones
Weil, C., & Marcuzzi, O. (1990) · General and Comparative Endocrinology · doi:10.1016/0016-6480(90)90080-6 · Cited by 21 · see citing works
Activation of Salmon GnRH mRNA Expression Prior to Differentiation of Precocious Males in Masu Salmon
Amano, M., Kitamura, S., Ikuta, K., et al. (1997) · General and Comparative Endocrinology · doi:10.1006/gcen.1996.6838 · Cited by 20 · see citing works
Seabream GnRH immunoreactivity in brain and pituitary of XX and XY Nile tilapia, Oreochromis niloticus during early development
Swapna, I., Sudhakumari, C. C., Sakai, F., et al. (2008) · Journal of Experimental Zoology Part A Ecological Genetics and Physiology · doi:10.1002/jez.467 · Cited by 19 · see citing works
Immunohistochemical localization of three GnRH systems in brain and pituitary of Japanese flounder
Pham, K. X., Amano, M., Amiya, N., et al. (2007) · Fisheries Science · doi:10.1111/j.1444-2906.2007.01443.x · Cited by 17 · see citing works
Cloning and functional analysis of the proximal promoter region of the three GnRH genes from the silver sea bream (Sparus sarba)
Hu, S., Chen, M. H., Lin, Y., et al. (2008) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2008.06.015 · Cited by 16 · see citing works
Patterns of proopiomelanotropin and proopiocortin gene expression and of immunohistochemistry for gonadotropin-releasing hormones (lGnRH-I and III) during the life cycle of a nonparasitic lamprey: Relationship to this adult life history type
Youson, J. H., Heinig, J. A., Khanam, S., et al. (2006) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2005.10.015 · Cited by 14 · see citing works
GnRH immunodetection in the brain of the holocephalan fish Chimaera monstrosa L.: Correlation to oocyte maturation
Masini, M. A., Prato, P., Vacchi, M., et al. (2008) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2008.02.016 · Cited by 9 · see citing works
Distribution of gonadotropin releasing-hormone-II in the house sparrow brain (Passer domesticus).
Stevenson, T. J., Arckens, L., & MacDougall-Shackleton, S. (2007) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2006.07.015 · Cited by 9 · see citing works
Molecular cloning and brain distribution of three types of gonadotropin‐releasing hormone from mummichog Fundulus heteroclitus
Ohkubo, M., Aranishi, F., & Shimizu, A. (2010) · Journal of Fish Biology · doi:10.1111/j.1095-8649.2009.02509.x · Cited by 9 · see citing works
Expression of gonadotrophin-releasing hormone binding sites in somatic tissues of the gilthead seabream (Sparus aurata): a quantitative autoradiographic study.
González-Martínez, D. A., Sarasquete, C., Pascual, E., et al. (2006) · PubMed · doi:10.14670/hh-21.1065 · Cited by 7 · see citing works
Immunohistochemical Localization of Gonadotropin-Releasing Hormone and Somatolactin During Sexual Maturation and Spawning of Lates niloticus
Khalil, N. A., El-Gama, A. E.-H. E., Gaber, S. A., et al. (2007) · Journal of Biological Sciences · doi:10.3923/jbs.2007.1102.1111 · Cited by 5 · see citing works
Neurosecretory neurons of the nucleus preopticus (NPO) express salmon GnRH mRNA and show reproduction phase-related variation in the female Indian major carp, Cirrhinus cirrhosus
Sakharkar, A. J., Mazumdar, M., Singru, P. S., et al. (2008) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2008.07.005 · Cited by 2 · see citing works

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Pieper, D. R., Gala, R. R., Schiff, M. A., et al. (1984) · Endocrinology · doi:10.1210/endo-115-3-1190 · Cited by 30 · see citing works
Reduction of Luteinzing Hormone Secretion Induced by Long‐Term Feed Restriction in Male Rats Is Associated with Increased Expression of GABA‐Synthesizing Enzymes Without Alterations of GnRH Gene Expression
Leonhardt, Shahab, S., Luft, Wuttke, & Jarry (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00377.x · Cited by 52 · see citing works
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Authors: Tuziak, S. M., & Volkoff, H.
Affiliations: Memorial University of Newfoundland (CA)
Corresponding author: Volkoff, Hélène
ORCID: Volkoff, Hélène
Venue: General and Comparative Endocrinology
Publisher: Elsevier BV
Published: 2013-04
Volume: 184
Pages: 9-21
ISSN: 0016-6480 (ISSN-L)
DOI: 10.1016/j.ygcen.2012.12.010
OpenAlex: W2005381202
Cited by: 20
References: 74
Citations by year: 2026: 2 · 2024: 1 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 1
FWCI: 2.01
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: General and Comparative Endocrinology (publishedVersion)
PubMed (publishedVersion)
Funders: Natural Sciences and Engineering Research Council of Canada
Topics: Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords: gonadotropin-releasing hormone, winter flounder, GnRH1, GnRH2, GnRH3, gene expression, fasting, food intake regulation, brain, optic tectum, hypothalamus, preoptic area, teleost reproduction
MeSH terms: Animals, Brain, Fasting, Flounder, Gonadotropin-Releasing Hormone, RNA, Messenger

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Gonadotrophin-releasing hormone in winter flounder (Pseudopleuronectes americanus): Molecular characterization, distribution and effects of fasting

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