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Btrim: A fast, lightweight adapter and quality trimming program for next-generation sequencing technologies
Open accessAbstract
Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples. Based on a modified Myers's bit-vector dynamic programming algorithm, Btrim can handle indels in adapters and barcodes. It removes low quality regions and trims off adapters at both or either end of the reads. A typical trimming of 30M reads with two sets of adapter pairs can be done in about a minute with a small memory footprint. Btrim is a versatile stand-alone tool that can be used as the first step in virtually all next-generation sequence analysis pipelines. The program is available at http://graphics.med.yale.edu/trim/.
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Metadata
- Authors
- Kong, Y.
- Venue
- Genomics
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 98
- Issue
- 2
- Pages
- 152-153
- ISSN
- 0888-7543 (ISSN-L)
- OpenAlex
- W2080958324
- Cited by
- 579
- References
- 0
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kong, Y. (2011). Btrim: A fast, lightweight adapter and quality trimming program for next-generation sequencing technologies. Genomics. https://doi.org/10.1016/j.ygeno.2011.05.009
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
